Diagnosis and evaluation of gastric cancer by positron emission tomography.

Abstract:

:Gastric cancer is the second leading cause of cancer mortality worldwide. The diagnosis of gastric cancer has been significantly improved with the broad availability of gastrointestinal endoscopy. Effective technologies for accurate staging and quantitative evaluation are still in demand to merit reasonable treatment and better prognosis for the patients presented with advanced disease. Preoperative staging using conventional imaging tools, such as computed tomography (CT) and endoscopic ultrasonography, is inadequate. Positron emission tomography (PET), using (18)F-fluorodeoxyglucose (FDG) as a tracer and integrating CT for anatomic localization, holds a promise to detect unsuspected metastasis and has been extensively used in a variety of malignancies. However, the value of FDG PET/CT in diagnosis and evaluation of gastric cancer is still controversial. This article reviews the current literature in diagnosis, staging, response evaluation, and relapse monitoring of gastric cancer, and discusses the current understanding, improvement, and future prospects in this area.

journal_name

World J Gastroenterol

authors

Wu CX,Zhu ZH

doi

10.3748/wjg.v20.i16.4574

subject

Has Abstract

pub_date

2014-04-28 00:00:00

pages

4574-85

issue

16

eissn

1007-9327

issn

2219-2840

journal_volume

20

pub_type

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