Prognostic implication of isolated tumor cells and micrometastases in regional lymph nodes of gastric cancer.

abstract：BACKGROUND:Identifying predictors of therapeutic response is the cornerstone of personalized medicine. AIM:To identify predictors of long-term mucosal healing (MH) in patients with Crohn's disease (CD) treated with tumor necrosis factor α (TNF-α) inhibitors. METHODS:Prospective single center study. Consecutive patien...

journal_title：World journal of gastroenterology

authors： Alfaro I,Masamunt MC,Planell N,López-García A,Castro J,Gallego M,Barastegui R,Giner A,Vara A,Salas A,Ricart E,Panés J,Ordás I

更新日期：2019-04-14 00:00:00

abstract：AIM:To investigate the implication of the hypoxia inducible factor HIF-1alpha mRNA in gastric carcinoma and its relation to the expression of vascular endothelial growth factor (VEGF) protein, tumor angiogenesis invasion/metastasis and the patient's survival. METHODS:In situ hybridization was used to examine expressio...

journal_title：World journal of gastroenterology

authors： Ma J,Zhang L,Ru GQ,Zhao ZS,Xu WJ

更新日期：2007-03-21 00:00:00

abstract：:This issue presents different new techniques aiming to increase our understanding of the gastrointestinal system and to improve treatment. The technologies cover selected methods to evoke and assess gut pain, new methods for imaging and physiological measurements, histochemistry, pharmacological modelling etc. There i...

journal_title：World journal of gastroenterology

authors： Drewes AM,Gregersen H

更新日期：2009-01-14 00:00:00

abstract：:Peritoneal carcinomatosis (PC) is one manifestation of metastatic colorectal cancer (CRC). Tumor growth on intestinal surfaces and associated fluid accumulation eventually result in bowel obstruction and incapacitating levels of ascites, which profoundly affect the quality of life for affected patients. PC appears res...

journal_title：World journal of gastroenterology

authors： Klaver YL,Lemmens VE,Nienhuijs SW,Luyer MD,de Hingh IH

更新日期：2012-10-21 00:00:00

abstract：:The paper provides a basic review of intestinal microflora and its importance in liver diseases. The intestinal microflora has many important functions, above all to maintain the microbial barrier against established as well as potential pathogens. Furthermore, it influences the motility and perfusion of the intestina...

journal_title：World journal of gastroenterology

authors： Lata J,Jurankova J,Kopacova M,Vitek P

更新日期：2011-06-28 00:00:00

abstract：:Acute pancreatitis is one of the most common diseases in the everyday's practise of gastroenterologists and surgeons. However, the physicians' therapeutic armamentarium is very limited. The present letter to the editor briefly describes the recent evidence from the literature with the aim to optimize a conservative ma...

journal_title：World journal of gastroenterology

authors： Petrov MS

更新日期：2008-10-14 00:00:00

abstract：:The liver is one of the most important organs in the body, performing a fundamental role in the regulation of diverse processes, among which the metabolism, secretion, storage, and detoxification of endogenous and exogenous substances are prominent. Due to these functions, hepatic diseases continue to be among the mai...

journal_title：World journal of gastroenterology

authors： Madrigal-Santillán E,Madrigal-Bujaidar E,Álvarez-González I,Sumaya-Martínez MT,Gutiérrez-Salinas J,Bautista M,Morales-González Á,García-Luna y González-Rubio M,Aguilar-Faisal JL,Morales-González JA

更新日期：2014-10-28 00:00:00

abstract：AIM:To assess the efficacy and safety of TECA type hybrid artificial liver support system (TECA-HALSS) in providing liver function of detoxification, metabolism and physiology by treating the patients with acute liver failure (ALF). METHODS:The porcine liver cells (1-2) x 10(10) were separated from the Chinese small s...

journal_title：World journal of gastroenterology

authors： Xue YL,Zhao SF,Luo Y,Li XJ,Duan ZP,Chen XP,Li WG,Huang XQ,Li YL,Cui X,Zhong DG,Zhang ZY,Huang ZQ

更新日期：2001-12-01 00:00:00

abstract：:We report a case of intraductal papillary neoplasm of the bile duct (IPNB) that developed in a patient with primary sclerosing cholangitis. A 46-year-old woman was admitted to our hospital with obstructive jaundice. The liver function tests demonstrated increased serum liver enzyme levels. Computed tomography showed d...

journal_title：World journal of gastroenterology

authors： Hachiya H,Kita J,Shiraki T,Iso Y,Shimoda M,Kubota K

更新日期：2014-11-14 00:00:00

abstract：AIM:To evaluate the diagnostic efficiency of endoscopic ultrasound (EUS) as the main imaging modality in patients with moderate suspicion of common bile duct stones (CBDS). METHODS:55 patients with moderate clinical suspicion of CBDS were prospectively included to the study and evaluated with EUS. This study was done ...

journal_title：World journal of gastroenterology

authors： Kohut M,Nowak A,Nowakowska-Dulawa E,Marek T,Kaczor R

更新日期：2003-03-01 00:00:00

abstract：:Colorectal anastomotic leakage (CAL) remains a major complication after colorectal surgery. Despite all efforts during the last decades, the incidence of CAL has not decreased. In this review, we summarize the available strategies regarding prevention, prediction and intervention of CAL and categorize them into three ...

journal_title：World journal of gastroenterology

authors： Sparreboom CL,Wu ZQ,Ji JF,Lange JF

更新日期：2016-08-28 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the major causes of morbidity and mortality in patients with chronic liver disease. Transarterial chemoembolization (TACE) can significantly improve the survival rate of patients with HCC and is the first treatment choice for patients who are not suitable for surgical resection...

journal_title：World journal of gastroenterology

authors： Yang K,Zhang XM,Yang L,Xu H,Peng J

更新日期：2016-05-28 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is one of the most common comorbidities associated with overweight and metabolic syndrome (MetS). Importantly, NAFLD is one of its most dangerous complications because it can lead to severe liver pathologies, including fibrosis, cirrhosis and hepatic cellular carcinoma. Given ...

journal_title：World journal of gastroenterology

authors： Mikolasevic I,Milic S,Turk Wensveen T,Grgic I,Jakopcic I,Stimac D,Wensveen F,Orlic L

更新日期：2016-11-21 00:00:00

abstract：AIM:To investigate the rate of Helicobacter pylori (H. pylori) resistance to clarithromycin among ethnic minority patients in Guangxi, explore the underlying mechanisms, and analyze factors influencing genotype distribution of H. pylori isolates. METHODS:H. pylori strains were isolated, cultured and subjected to drug ...

journal_title：World journal of gastroenterology

authors： Zhao LJ,Huang YQ,Chen BP,Mo XQ,Huang ZS,Huang XF,Wei LD,Wei HY,Chen YH,Tang HY,Huang GR,Qin YC,Li XH,Wang LY

更新日期：2014-04-28 00:00:00

abstract：AIM:To evaluate the clinical advantages of single-port laparoscopic hepatectomy (SPLH) compare to multi-port laparoscopic hepatectomy (MPLH). METHODS:We retrospectively reviewed the medical records of 246 patients who underwent laparoscopic liver resection between January 2008 and December 2015 at our hospital. We div...

journal_title：World journal of gastroenterology

authors： Han JH,You YK,Choi HJ,Hong TH,Kim DG

更新日期：2018-01-21 00:00:00

abstract：AIM:To investigate the relationship between Helicobacter pylori (H. pylori) and mucin expression in gastric mucosa. METHODS:English Medical literature searches were conducted for gastric mucin expression in H. pylori infected people vs uninfected people. Searches were performed up to December 31(th) 2014, using MEDLIN...

journal_title：World journal of gastroenterology

authors： Niv Y

更新日期：2015-08-21 00:00:00

abstract：AIM:To discuss the rationality of extended radical resection (ERR) and to guide the surgical treatment of rectal cancer. METHODS:Total 211 patients who underwent ERR from 1981 to 1987 (follow-up rate of 94.8 %) were selected to study the patterns of lymphatic metastasis and therapeutic effect. The control group was ma...

journal_title：World journal of gastroenterology

authors： Dong XS,Xu HT,Yu ZW,Liu M,Cu BB,Zhao P,Wang XS

更新日期：2003-05-01 00:00:00

abstract：AIM:To evaluate the efficacy and safety of traditional Chinese surgical treatment for anal fistulae with secondary tracks and abscess. METHODS:Sixty patients with intersphincteric or transsphincteric anal fistulas with secondary tracks and abscess were randomly divided into study group [suture dragging combined with p...

journal_title：World journal of gastroenterology

authors： Wang C,Lu JG,Cao YQ,Yao YB,Guo XT,Yin HQ

更新日期：2012-10-28 00:00:00

abstract：:Helicobacter pylori (H. pylori) infection has been clearly linked to peptic ulcer disease and some gastrointestinal malignancies. Increasing evidence demonstrates possible associations to disease states in other organ systems, known as the extraintestinal manifestations of H. pylori. Different conditions associated wi...

journal_title：World journal of gastroenterology

authors： Wong F,Rayner-Hartley E,Byrne MF

更新日期：2014-09-14 00:00:00

abstract：AIM:To prospectively explore the role of carcinoembryonic antigen (CEA) in gallbladder bile in patients with colorectal carcinoma and the morphological and clinical features of neoplasia and the occurrence of hepatic metastases. METHODS:CEA levels in the gallbladder and peripheral blood were studied in 44 patients wit...

journal_title：World journal of gastroenterology

authors： Waisberg J,Palma RT,Neto LC,Martins LC,Oliveira MS,Nagashima CA,Godoy AC,Goffi FS

更新日期：2003-07-01 00:00:00

abstract：:Gastric cancer and liver cancer are among the most common malignancies and the leading causes of death worldwide, due to late detection and high recurrence rates. Today, these cancers have a heavy socioeconomic burden, for which a full understanding of their pathophysiological features is warranted to search for promi...

journal_title：World journal of gastroenterology

authors： Cao DX,Li ZJ,Jiang XO,Lum YL,Khin E,Lee NP,Wu GH,Luk JM

更新日期：2012-08-14 00:00:00

abstract：:Liver regeneration after major surgery may activate occult micrometastases and facilitate tumor growth, leading to liver tumor recurrence. Molecular changes during liver regeneration can provide a microenvironment that stimulates intrahepatic tumor propagation through alterations in cellular signaling pathways, where ...

journal_title：World journal of gastroenterology

authors： Shi JH,Line PD

更新日期：2014-11-21 00:00:00

abstract：AIM:To develop a potent and safe gene therapy for esophageal cancer. METHODS:An expression vector carrying fusion suicide gene (yCDglyTK) and shRNA against vascular endothelial growth factor (VEGF) was constructed and delivered into EC9706 esophageal cancer cells by calcium phosphate nanoparticles (CPNP). To achieve t...

journal_title：World journal of gastroenterology

authors： Liu T,Wu HJ,Liang Y,Liang XJ,Huang HC,Zhao YZ,Liao QC,Chen YQ,Leng AM,Yuan WJ,Zhang GY,Peng J,Chen YH

更新日期：2016-06-21 00:00:00

abstract：:The anti-tumor necrosis factor (TNF)alpha medications demonstrate efficacy in the induction of remission and its maintenance in numerous chronic inflammatory conditions. With the increasing number of patients receiving anti-TNFalpha agents, however, less common adverse reactions will occur. Cutaneous eruptions complic...

journal_title：World journal of gastroenterology

authors： Salama M,Lawrance IC

更新日期：2009-09-21 00:00:00

abstract：AIM:To determine whether local antibiotic resistance involves P-glycoprotein (Pgp)-mediated active drug out-pumping during Helicobacter pylori (H pylori) infection treatment with classic antibiotic therapy. METHODS:Pgp activity was determined in gastric mucosa biopsy specimens obtained from 53 patients with pathohisto...

journal_title：World journal of gastroenterology

authors： Babic Z,Svoboda-Beusan I,Kucisec-Tepes N,Dekaris D,Troskot R

更新日期：2005-05-14 00:00:00

abstract：AIM:To investigate the gastric emptying after bowel preparation to allow general anaesthesia. METHODS:A prospective, non-comparative, and non-randomized trial was performed and registered on Eudra CT database (2011-002953-80) and on www.trial.gov (NCT01398098). All patients had a validated indication for colonoscopy a...

journal_title：World journal of gastroenterology

authors： Coriat R,Polin V,Oudjit A,Henri F,Dhooge M,Leblanc S,Delchambre C,Esch A,Tabouret T,Barret M,Prat F,Chaussade S

更新日期：2014-10-07 00:00:00

abstract：AIM:To explore the preliminary identification of serum protein pattern models that may be novel potential biomarkers in the detection of gastric cancer. METHODS:A total of 130 serum samples, including 70 from patients with gastric cancer and 60 from healthy adults, were detected by surface-enhanced laser desorption an...

journal_title：World journal of gastroenterology

authors： Qian HG,Shen J,Ma H,Ma HC,Su YH,Hao CY,Xing BC,Huang XF,Shou CC

更新日期：2005-10-28 00:00:00

abstract：:We review the case of a 74-year-old patient with advanced colon cancer who suffered recurrent bouts of hypoglycemia. A state of inappropriate, non-suppressed hyperinsulinism in the presence of severe hypoglycemia was diagnosed. We finally discuss the known mechanisms behind fasting hypoglycemia in patients with advanc...

journal_title：World journal of gastroenterology

authors： Díaz R,Aparicio J,Mendizábal A,Faus M,Fleitas T,Aparisi F,Martín M

更新日期：2008-03-28 00:00:00

abstract：BACKGROUND:The digestive tract is the maximal immunizing tissue in the body, and mucosal integrity and functional status of the gut is very important to maintain a healthy organism. Severe infection is one of the most common causes of gastrointestinal dysfunction, and the pathogenesis is closely related to endotoxemia ...

journal_title：World journal of gastroenterology

authors： Wang W,Sun M,Zheng YL,Sun LY,Qu SQ

更新日期：2019-06-21 00:00:00

abstract：AIM:To construct pcDNA3.1-Egr.1p-p16 recombinant plasmid and investigate the expression of p16 in pancreatic cancer JF305 cells induced by radiation and the feasibility of gene radiotherapy for pancreatic carcinoma. METHODS:Human p16 cDNA was ligated to the downstream of Egr-1 promotor to construct pcDNA3.1-Egr.1p-p16...

journal_title：World journal of gastroenterology

authors： Ma HB,Wang XJ,Di ZL,Xia H,Li Z,Liu J,Ma J,Kang HF,Wu CM,Bai MH

更新日期：2007-08-21 00:00:00