"Rescue" regimens after Helicobacter pylori treatment failure.

abstract：AIM:To explore the inducing effect of human mutant p27 gene on the apoptosis of the human gastric cancer cell line MKN-45 and its associated mechanisms. METHODS:The recombinant adenovirus Ad-p27mt was constructed to infect the human gastric cancer cell line MKN-45. Using flow cytometry, TUNEL assay and DNA fragment an...

journal_title：World journal of gastroenterology

authors： Zhu JS,Wang L,Cheng GQ,Li Q,Zhu ZM,Zhu L

更新日期：2005-12-21 00:00:00

abstract：:Gluten-sensitive enteropathy, also known as coeliac disease (CD), is an autoimmune disorder occurring in genetically susceptible individuals that damages the small intestine and interferes with the absorption of other nutrients. As it is triggered by dietary gluten and related prolamins present in wheat, rye and barle...

journal_title：World journal of gastroenterology

authors： Sziksz E,Pap D,Veres G,Fekete A,Tulassay T,Vannay Á

更新日期：2014-06-07 00:00:00

abstract：AIM:To assess the efficacy and safety of a new treatment modality, cellular immune therapy based on personalized peptide vaccination (PPV-DC-CTL) combined with radiotherapy, for treating advanced hepatocellular carcinoma (HCC). METHODS:A total of nine patients with advanced HCC were enrolled. Multidisciplinary consult...

journal_title：World journal of gastroenterology

authors： Shen J,Wang LF,Zou ZY,Kong WW,Yan J,Meng FY,Chen FJ,Du J,Shao J,Xu QP,Ren HZ,Li RT,Wei J,Qian XP,Liu BR

更新日期：2017-08-07 00:00:00

abstract：:Significant disparities exist between genders for the development and progression of several gastro-intestinal (GI) diseases including cancer. Differences in incidence between men vs women for colon, gastric and hepatocellular cancers suggest a role for steroid sex hormones in regulation of GI carcinogenesis. Involvem...

journal_title：World journal of gastroenterology

authors： Sukocheva OA,Li B,Due SL,Hussey DJ,Watson DI

更新日期：2015-05-28 00:00:00

abstract：AIM:To investigate the designation, synthesis and biological activity of against vascular endothelial growth factor165 (VEGF165) ribozyme. METHODS:The ribozyme against VEGF165 was designed with computer. The transcriptional vector was constructed which included the anti-VEGF165 ribozyme and 5', 3' self-splicing ribozy...

journal_title：World journal of gastroenterology

authors： Gu ZP,Wang YJ,Wu Y,Li JG,Chen NA

更新日期：2004-05-15 00:00:00

abstract：AIM:To investigate whether alphastatin could inhibit human gastric cancer growth and furthermore whether sphingosine kinase (SPK) activity is involved in this process. METHODS:Using migration assay, MTT assay and Matrigel assay, the effect of alphastatin on vascular endothelial cells (ECs) was evaluated in vitro. SPK ...

journal_title：World journal of gastroenterology

authors： Chen L,Li T,Li R,Wei B,Peng Z

更新日期：2006-07-14 00:00:00

abstract：AIM:To observe expression of CD14 protein and CD14 gene in rat liver sinusoidal endothelial cells (LSECs) during endotoxemia, and the role of CD14 protein in the activation of lipopolysaccharide (LPS)-induced LSECs. METHODS:Wistar rat endotoxemia model was established first by injection of a dose of LPS (5mg/kg, Esche...

journal_title：World journal of gastroenterology

authors： Gong JP,Dai LL,Liu CA,Wu CX,Shi YJ,Li SW,Li XH

更新日期：2002-06-01 00:00:00

abstract：:Bowel preparation is a core issue in colonoscopy, as it is closely related to the quality of the procedure. Patients often find that bowel preparation is the most unpleasant part of the examination. It is widely accepted that the quality of cleansing must be excellent to facilitate detecting neoplastic lesions. In spi...

journal_title：World journal of gastroenterology

authors： Parra-Blanco A,Ruiz A,Alvarez-Lobos M,Amorós A,Gana JC,Ibáñez P,Ono A,Fujii T

更新日期：2014-12-21 00:00:00

abstract：:High-quality data remains scarce in terms of optimal management strategies in the elderly inflammatory bowel disease (IBD) population. Indeed, available trials have been mostly retrospective, of small sample size, likely owing to under-representation of such a population in the major randomized controlled trials. Howe...

journal_title：World journal of gastroenterology

authors： LeBlanc JF,Wiseman D,Lakatos PL,Bessissow T

更新日期：2019-08-14 00:00:00

abstract：AIM:To perform a meta-analysis of observational studies to further elucidate the relationship between oral bisphosphonate use and gastrointestinal cancer risk. METHODS:Systematic literature search was conducted in MEDLINE, EMBASE, and the Cochrane Library to identify studies through January 2011. Search terms were "bi...

journal_title：World journal of gastroenterology

authors： Oh YH,Yoon C,Park SM

更新日期：2012-10-28 00:00:00

abstract：:Two major types of cancer occur in the esophagus: squamous cell carcinoma, which is associated with chronic smoking and alcohol consumption, and adenocarcinoma, which typically arises in gastric reflux-associated Barrett's esophagus. Although there is increasing incidence of esophageal adenocarcinoma in Western counti...

journal_title：World journal of gastroenterology

authors： Sasaki Y,Tamura M,Koyama R,Nakagaki T,Adachi Y,Tokino T

更新日期：2016-02-21 00:00:00

abstract：:The importance of the safety of healthy living liver donors is widely recognized during donor hepatectomy which is associated with blood loss, transfusion, and subsequent post-operative morbidity. Although the low central venous pressure (CVP) technique can still be effective, it may not be advantageous concerning the...

journal_title：World journal of gastroenterology

authors： Choi SS,Kim SH,Kim YK

更新日期：2015-12-07 00:00:00

abstract：AIM:To investigate the effect of a fat rich diet on non-steroidal anti-inflammatory drug (NSAID)-induced mucosal damage in the murine small intestine. METHODS:C57BL6 mice were fed 4 types of diets with or without indomethacin. One group was fed standard laboratory chow. The other groups were fed a fat diet consisting ...

journal_title：World journal of gastroenterology

authors： Ueda T,Hokari R,Higashiyama M,Yasutake Y,Maruta K,Kurihara C,Tomita K,Komoto S,Okada Y,Watanabe C,Usui S,Nagao S,Miura S

更新日期：2015-01-07 00:00:00

abstract：:The incidence of colorectal cancer (CRC) is on the rise, and the prognosis for patients with recurrent or metastatic disease is extremely poor. Although chemotherapy and radiation therapy can improve survival rates, it is imperative to integrate alternative strategies such as immunotherapy to improve outcomes for pati...

journal_title：World journal of gastroenterology

authors： Koido S,Ohkusa T,Homma S,Namiki Y,Takakura K,Saito K,Ito Z,Kobayashi H,Kajihara M,Uchiyama K,Arihiro S,Arakawa H,Okamoto M,Gong J,Tajiri H

更新日期：2013-12-14 00:00:00

abstract：AIM:To investigate the risk association and compare the onset age of hepatocellular carcinoma (HCC) patients in Taiwan with different genotypes of MDM2-SNP309. METHODS:We analyzed MDM2-SNP309 genotypes from 58 patients with HCC and 138 cancer-free healthy controls consecutively. Genotyping of MDM2-SNP309 was conducted...

journal_title：World journal of gastroenterology

authors： Leu JD,Lin IF,Sun YF,Chen SM,Liu CC,Lee YJ

更新日期：2009-11-28 00:00:00

abstract：AIM:To investigate the growth inhibitory mechanism of four caged xanthones from Garcinia hanburyi in cholangiocarcinoma (CCA) KKU-100 and KKU-M156 cells. METHODS:Four caged xanthones, selected on the basis of their anticancer potency and chemical structure diversities (i.e. isomorellin, isomorellinol, forbesione and g...

journal_title：World journal of gastroenterology

authors： Hahnvajanawong C,Boonyanugomol W,Nasomyon T,Loilome W,Namwat N,Anantachoke N,Tassaneeyakul W,Sripa B,Namwat W,Reutrakul V

更新日期：2010-05-14 00:00:00

abstract：AIM:To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs) therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a systematic search of MEDLINE/PubMed and seven other databases through January 1990 to March 2017 for published studies that evaluated the associatio...

journal_title：World journal of gastroenterology

authors： Trifan A,Stanciu C,Girleanu I,Stoica OC,Singeap AM,Maxim R,Chiriac SA,Ciobica A,Boiculese L

更新日期：2017-09-21 00:00:00

abstract：AIM:To evaluate the feasibility and utility of confocal laser endomicroscopy (CLE) in the description of normal gastrointestinal (GI) mucosa and in the diagnosis of GI disorders in children, in comparison to histology. METHODS:Forty-four patients (19 female) median age 10.9 years (range 0.7-16.6 years) with suspected ...

journal_title：World journal of gastroenterology

authors： Venkatesh K,Cohen M,Evans C,Delaney P,Thomas S,Taylor C,Abou-Taleb A,Kiesslich R,Thomson M

更新日期：2009-05-14 00:00:00

abstract：AIM:To investigate the effects of exogenous melatonin on bacterial translocation and apoptosis in a rat ulcerative colitis model. METHODS:Rats were randomly assigned to three groups: group I: control, group II: experimental colitis, group III: colitis plus melatonin treatment. On d 11 after colitis, plasma tumor necro...

journal_title：World journal of gastroenterology

authors： Akcan A,Kucuk C,Sozuer E,Esel D,Akyildiz H,Akgun H,Muhtaroglu S,Aritas Y

更新日期：2008-02-14 00:00:00

abstract：AIM:To evaluate the utility of local tumor therapy combined with percutaneous transhepatic biliary drainage (PTBD) for malignant obstructive biliary disease. METHODS:A total of 233 patients with malignant biliary obstruction were treated in our hospital with PTBD by placement of metallic stents and/or plastic tubes. A...

journal_title：World journal of gastroenterology

authors： Qian XJ,Zhai RY,Dai DK,Yu P,Gao L

更新日期：2006-01-14 00:00:00

abstract：:A 36-year-old male Asian immigrant with a history of hepatitis B and hepatitis C related unresectable hepatocellular carcinoma in the left lobe of the liver presented with hematemesis and severe anemia. He was diagnosed with a liver mass that was resected 8 years ago described as a benign tumor in his home country. He...

journal_title：World journal of gastroenterology

authors： Sayana H,Yousef O,Clarkston WK

更新日期：2013-11-14 00:00:00

abstract：:Endoscopic mucosal resection (EMR) allows the removal of flat or sessile lesions, laterally spreading tumors, and carcinoma of the colon or the rectum limited to the mucosa or the superficial submucosa. Acute appendicitis is the most common abdominal emergency requiring emergency surgery, and it is also a rare complic...

journal_title：World journal of gastroenterology

authors： Nemoto Y,Tokuhisa J,Shimada N,Gomi T,Maetani I

更新日期：2015-07-21 00:00:00

abstract：:The small intestine is approximately 5-6 m long and occupies a large area in the abdominal cavity. These factors preclude the use of ordinary endoscopy and X-ray to thoroughly examine the small intestine for bleeding of vascular malformations. Thus, the diagnosis of intestinal bleeding is very difficult. A 47-year-old...

journal_title：World journal of gastroenterology

authors： Cui J,Huang LY,Lin SJ,Yi LZ,Wu CR,Zhang B

更新日期：2014-10-14 00:00:00

abstract：AIM:To explore the preliminary identification of serum protein pattern models that may be novel potential biomarkers in the detection of gastric cancer. METHODS:A total of 130 serum samples, including 70 from patients with gastric cancer and 60 from healthy adults, were detected by surface-enhanced laser desorption an...

journal_title：World journal of gastroenterology

authors： Qian HG,Shen J,Ma H,Ma HC,Su YH,Hao CY,Xing BC,Huang XF,Shou CC

更新日期：2005-10-28 00:00:00

abstract：BACKGROUND:The management strategies for recurrent ampullary adenoma after endoscopic papillectomy are still controversial. Patients with the recurrent papillary lesions need to receive repetitive endoscopic interventions due to the limitations of conventional endoscopic techniques. AIM:To assess the feasibility, effi...

journal_title：World journal of gastroenterology

authors： Wang ZK,Liu F,Wang Y,Wang XD,Tang P,Li W

更新日期：2020-10-07 00:00:00

abstract：:Based on reviews of the literature and experts' consensus, the Chinese Society of Hepatology developed guidelines for the diagnosis and treatment of liver cirrhosis, in order to improve clinical practice. In addition to what has been covered in previously published guidelines on the management of cirrhosis complicatio...

journal_title：World journal of gastroenterology

authors： Xu XY,Ding HG,Li WG,Xu JH,Han Y,Jia JD,Wei L,Duan ZP,Ling-Hu EQ,Zhuang H

更新日期：2020-12-07 00:00:00

abstract：:The prognosis of patients with HCC still remains dismal. The life expectancy of HCC patients is hard to predict because of the high possibility of postoperative recurrence. Many factors, such as patient's general conditions, macroscopic tumor morphology, as well as tumor histopathology features, have been proven of pr...

journal_title：World journal of gastroenterology

authors： Qin LX,Tang ZY

更新日期：2002-04-01 00:00:00

abstract：AIM:To investigate long-term outcome in obscure gastrointestinal bleeding (OGIB) after negative capsule endoscopy (CE) and identify risk factors for rebleeding. METHODS:A total of 113 consecutive patients underwent CE for OGIB from May 2003 to June 2010 at Seoul National University Hospital. Ninety-five patients (84.1...

journal_title：World journal of gastroenterology

authors： Koh SJ,Im JP,Kim JW,Kim BG,Lee KL,Kim SG,Kim JS,Jung HC

更新日期：2013-03-14 00:00:00

abstract：:Cytomegalovirus (CMV) infection is a common complication after liver transplantation, and it is associated with multiple direct and indirect effects. Management of CMV infection and disease has evolved over the years, and clinical guidelines have been recently updated. Universal antiviral prophylaxis and a pre-emptive...

journal_title：World journal of gastroenterology

authors： Marcelin JR,Beam E,Razonable RR

更新日期：2014-08-21 00:00:00

abstract：:The search for biomarkers that characterize specific aspects of inflammatory bowel disease (IBD), has received substantial interest in the past years and is moving forward rapidly with the help of modern technologies. Nevertheless, there is a direct demand to identify adequate biomarkers for predicting and evaluating ...

journal_title：World journal of gastroenterology

authors： Quetglas EG,Mujagic Z,Wigge S,Keszthelyi D,Wachten S,Masclee A,Reinisch W

更新日期：2015-11-28 00:00:00