Abstract:
AIM:To evaluate the long-term efficacy of endoscopic resection (ER) for small (≤ 4.0 cm) gastric gastrointestinal stromal tumors (GISTs) originating from the muscularis propria layer. METHODS:Between June 2005 and February 2015, we retrospectively analyzed 229 consecutive patients with gastric MP-GISTs who underwent ER with a follow-up at least 36 mo. The main outcome measurements included complete resection rate, complications, and long-term follow-up outcomes. RESULTS:ER included endoscopic muscularis excavation in 179 cases, endoscopic full-thickness resection in 32 cases, and submucosal tunneling endoscopic resection in 18 cases. The median size of GISTs was 1.90 cm. Of the 229 GISTs, 147 were very low risk, 72 were low risk, 8 were intermediate risk, and 2 were high risk. Short-term outcomes showed the complete resection rate was 96.5%, and 8 patients (3.5%) had complications. Of the 8 patients with complications, only one patient required surgical intervention. Long-term outcomes showed 225 patients were actively followed-up until composition of this manuscript. The remaining 4 patients were lost because of unrelated death. During the follow-up period (median, 57 mo), no residual, recurrent lesions, or distant metastasis were detected in any patients. Binary logistic regression analysis showed tumor size was a risk factor associated with a high mitotic index (≥ 5/50 HPF) of GISTs (P = 0.002). CONCLUSION:ER seems to be an effective and safe method for gastric MP-GISTs ≤ 4.0 cm, and, for some intermediate or high risk GISTs, adjuvant therapy and/or additional surgery might be required to reduce the risk of recurrence or metastasis.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Zhang Y,Mao XL,Zhou XB,Yang H,Zhu LH,Chen G,Ye LPdoi
10.3748/wjg.v24.i27.3030subject
Has Abstractpub_date
2018-07-21 00:00:00pages
3030-3037issue
27eissn
1007-9327issn
2219-2840journal_volume
24pub_type
杂志文章abstract:AIM:To systematically review literature addressing three key psychologically-oriented controversies associated with gastroparesis. METHODS:A comprehensive search of PubMed, CINAHL, and PsycINFO databases was performed to identify literature addressing the relationship between gastroparesis and psychological factors. T...
journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v23.i7.1298
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abstract::Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and leading cause of death among patients with cirrhosis. Treatment guidelines are based according to the Barcelona Clinic Liver Cancer staging system. The choice among therapeutic options that include liver resection, liver transplantation, loco...
journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v20.i30.10223
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v19.i4.516
更新日期:2013-01-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v4.i4.323
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pub_type: 社论,评审
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doi:10.3748/wjg.v20.i46.17468
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journal_title:World journal of gastroenterology
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doi:10.3748/wjg.v13.i39.5273
更新日期:2007-10-21 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v17.i2.249
更新日期:2011-01-14 00:00:00
abstract::Toxic hepatitis or drug-induced liver injury encompasses a spectrum of clinical disease ranging from mild biochemical abnormalities to acute liver failure. The advantages of a long half-life, wide spectrum, high tissue penetration rate, and a good safety profile, make ceftriaxone, a third-generation cephalosporin, a f...
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pub_type: 杂志文章
doi:10.3748/wjg.15.2669
更新日期:2009-06-07 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2014-03-21 00:00:00
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pub_type: 杂志文章
doi:10.3748/wjg.v11.i2.171
更新日期:2005-01-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,随机对照试验
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更新日期:2010-01-07 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2014-09-21 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v18.i28.3681
更新日期:2012-07-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v12.i43.6909
更新日期:2006-11-21 00:00:00
abstract::We review the case of a 74-year-old patient with advanced colon cancer who suffered recurrent bouts of hypoglycemia. A state of inappropriate, non-suppressed hyperinsulinism in the presence of severe hypoglycemia was diagnosed. We finally discuss the known mechanisms behind fasting hypoglycemia in patients with advanc...
journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.14.1952
更新日期:2008-03-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v16.i18.2235
更新日期:2010-05-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.14.1370
更新日期:2008-03-07 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v11.i5.760
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pub_type: 杂志文章,评审
doi:10.3748/wjg.v26.i43.6770
更新日期:2020-11-21 00:00:00
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pub_type: 杂志文章,评审
doi:10.3748/wjg.v19.i42.7292
更新日期:2013-11-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v17.i42.4682
更新日期:2011-11-14 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2012-09-21 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v18.i4.340
更新日期:2012-01-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v26.i45.7242
更新日期:2020-12-07 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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更新日期:2000-02-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2015-04-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v17.i15.2007
更新日期:2011-04-21 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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更新日期:2015-08-07 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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更新日期:2004-09-01 00:00:00