Current management of hepatocellular carcinoma.

abstract：:Chronic hepatitis B virus (HBV) infection is a critical risk factor for the carcinogenesis and progression of hepatocellular carcinoma (HCC). It promotes HCC development by inducing liver fibrogenesis, genetic and epigenetic alterations, and the expression of active viral-coded proteins. Effective antiviral treatments...

journal_title：World journal of gastroenterology

authors： Zhang YQ,Guo JS

更新日期：2015-04-07 00:00:00

abstract：:Repeated surveys from Europe, the United States, Australia, and New Zealand have shown that adherence to an evidence-based perioperative care protocol, such as Enhanced Recovery After Surgery (ERAS), has been generally low. It is of great importance to support the implementation of the ERAS protocol as it has been sho...

journal_title：World journal of gastroenterology

authors： Segelman J,Nygren J

更新日期：2014-11-28 00:00:00

abstract：AIM:To clarify the expression and role of Ephrin receptor A4 (EphA4) in gastric cancer in relation to clinicopathological characteristics and the expression of fibroblast growth factor receptor 1 (FGFR1) and ephrin ligands. METHODS:Eleven gastric carcinoma cell lines, 24 paired surgical fresh specimens of gastric aden...

journal_title：World journal of gastroenterology

authors： Oki M,Yamamoto H,Taniguchi H,Adachi Y,Imai K,Shinomura Y

更新日期：2008-10-07 00:00:00

abstract：AIM:To study the differential protein profile in serum of hepatitis B patients. METHODS:Serum samples were obtained from patients with chronic hepatitis B who were receiving peginterferon alfa-2b. The serum samples were subjected to albumin depletion and analyzed by two-dimensional gel electrophoresis (2-DE). Differen...

journal_title：World journal of gastroenterology

authors： Kuakarn S,SomParn P,Tangkijvanich P,Mahachai V,Thongboonkerd V,Hirankarn N

更新日期：2013-08-21 00:00:00

abstract：AIM:Quasispecies of hepatitis C virus (HCV) are the foundation for rapid sequence evolution of HCV to evade immune surveillance of hosts. The consensus sequence evolution of a segment of HCV NS3 region, which encompasses putative cytotoxic T cell epitopes, was evaluated. METHODS:Three male patients, infected with HCV ...

journal_title：World journal of gastroenterology

authors： Guo HZ,Yin Y,Wang WL,Zhang CS,Wang T,Wang Z,Zhang J,Cheng H,Wang HT

更新日期：2004-03-15 00:00:00

abstract：AIM:To investigate the effect of Chaiqinchengqi decoction (CQCQD) on sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) mRNA expression of pancreatic tissues in acute pancreatitis (AP) rats. METHODS:Thirty Sprague-Dawley (SD) rats were randomized into control group, AP group and CQCQD group (n = 3 x 10). The rats in the ...

journal_title：World journal of gastroenterology

authors： Xue P,Deng LH,Zhang ZD,Yang XN,Xia Q,Xiang DK,Huang L,Wan MH

更新日期：2008-04-21 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease that might affect up to one-third of the adult population in industrialised countries. NAFLD incorporates histologically and clinically different non-alcoholic entities; fatty liver (NAFL, steatosis hepatis) and steatohepatitis (NASH-characterised by...

journal_title：World journal of gastroenterology

authors： Firneisz G

更新日期：2014-07-21 00:00:00

abstract：BACKGROUND:Accumulating evidence has revealed that several long non-coding ribonucleic acids (lncRNAs) are crucial in the progress of hepatocellular carcinoma (HCC). AIM:To classify a long non-coding RNA, i.e., lncRNA W5, and to determine the clinical significance and potential roles of lncRNA W5 in HCC. METHODS:The ...

journal_title：World journal of gastroenterology

authors： Lei GL,Fan HX,Wang C,Niu Y,Li TL,Yu LX,Hong ZX,Yan J,Wang XL,Zhang SG,Ren MJ,Yang PH

更新日期：2021-01-07 00:00:00

abstract：AIM:To analyze the clinicopathologic features and the prognosis of primary intestinal lymphoma. METHODS:Patients were included in the study based on standard diagnostic criteria for primary gastrointestinal lymphoma, and were treated at Sun Yat-sen University Cancer Centre between 1993 and 2008. RESULTS:The study com...

journal_title：World journal of gastroenterology

authors： Wang GB,Xu GL,Luo GY,Shan HB,Li Y,Gao XY,Li JJ,Zhang R

更新日期：2011-11-07 00:00:00

abstract：AIM:To investigate the antibacterial effects of a crude extract of maggots against Escherichia coli (E. coli) and the underlying mechanisms, and to separate and purify the crude extract of maggots to assess the antibacterial effects of the active ingredients in the crude extract. METHODS:Different concentrations of th...

journal_title：World journal of gastroenterology

authors： Ge QS,Zhang HM,Liu X,Wang SY,Lv DC,Li XD

更新日期：2015-02-07 00:00:00

abstract：:The aetiology of primary sclerosing cholangitis (PSC) is not known and controversy exists as to whether PSC should be denominated an autoimmune disease. A large number of autoantibodies have been detected in PSC patients, but the specificity of these antibodies is generally low, and the frequencies vary largely betwee...

journal_title：World journal of gastroenterology

authors： Hov JR,Boberg KM,Karlsen TH

更新日期：2008-06-28 00:00:00

abstract：AIM:To study the relationship between Helicobacter pylori (H. pylori) and gastric carcinoma and its possible pathogenesis by H. pylori. METHODS:DNEL technique and immunohistochemical technique were used to study the state of apoptosis, proliferation and p53 gene expression. A total of 100 gastric mucosal biopsy specim...

journal_title：World journal of gastroenterology

authors： Zhang Z,Yuan Y,Gao H,Dong M,Wang L,Gong YH

更新日期：2001-12-01 00:00:00

abstract：AIM:To evaluate the effects of protein deprivation on the myenteric plexus of the esophagus of weanling rats. METHODS:Pregnant female Wistar rats were divided into 2 groups: nourished (N), receiving normal diet, and undernourished (D), receiving a protein-deprived diet, which continued after birth. At twenty-one days ...

journal_title：World journal of gastroenterology

authors： Liberti EA,Fontes RB,Fuggi VM,Maifrino LB,Souza RR

更新日期：2007-07-14 00:00:00

abstract：AIM:To investigate the possible involvement of 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase [1alpha-25(OH) (2) D(3)] in butyrate-induced differentiation in human intestinal cell line Caco-2 cells. METHODS:Caco-2 cells were incubated either with 3 mmol/L butyrate and 1 micromol/L 25(OH) (2) D(3) or with 1 micromol/L 1al...

journal_title：World journal of gastroenterology

authors： Schröder O,Turak S,Daniel C,Gaschott T,Stein J

更新日期：2005-12-07 00:00:00

abstract：AIM:To analyze small intestinal bacterial overgrowth in school-aged children and the relationship between hydrogen and methane production in breath tests. METHODS:This transversal study included 85 children residing in a slum and 43 children from a private school, all aged between 6 and 10 years, in Osasco, Brazil. Fo...

journal_title：World journal of gastroenterology

authors： Mello CS,Tahan S,Melli LC,Rodrigues MS,de Mello RM,Scaletsky IC,de Morais MB

更新日期：2012-11-07 00:00:00

abstract：AIM:To discuss the rationality of extended radical resection (ERR) and to guide the surgical treatment of rectal cancer. METHODS:Total 211 patients who underwent ERR from 1981 to 1987 (follow-up rate of 94.8 %) were selected to study the patterns of lymphatic metastasis and therapeutic effect. The control group was ma...

journal_title：World journal of gastroenterology

authors： Dong XS,Xu HT,Yu ZW,Liu M,Cu BB,Zhao P,Wang XS

更新日期：2003-05-01 00:00:00

abstract：AIM:To evaluate the predictive value of preoperative predictors for portal vein thrombosis (PVT) after splenectomy with periesophagogastric devascularization. METHODS:In this prospective study, 69 continuous patients with portal hypertension caused by hepatitis B cirrhosis underwent splenectomy with periesophagogastri...

journal_title：World journal of gastroenterology

authors： Zhang Y,Wen TF,Yan LN,Yang HJ,Deng XF,Li C,Wang C,Liang GL

更新日期：2012-04-21 00:00:00

abstract：AIM:To investigate the intestinal anti-inflammatory effect and mechanism of a probiotic Lactobacillus salivarius ssp. salivarius CECT5713 in the TNBS model of rat colitis. METHODS:Female Wistar rats (180-200 g) were used in this study. A group of rats were administered orally the probiotic L. salivarius ssp. salivariu...

journal_title：World journal of gastroenterology

authors： Peran L,Camuesco D,Comalada M,Nieto A,Concha A,Diaz-Ropero MP,Olivares M,Xaus J,Zarzuelo A,Galvez J

更新日期：2005-09-07 00:00:00

abstract：AIM:To assess the utility of contrast-enhanced ultrasonography (CEUS) with a second-generation contrast medium in the differential diagnosis between mass-forming pancreatitis and pancreatic carcinoma. METHODS:From our radio-pathology database, we retrieved all the patients affected by mass-forming pancreatitis or panc...

journal_title：World journal of gastroenterology

authors： D'Onofrio M,Zamboni G,Tognolini A,Malago R,Faccioli N,Frulloni L,Pozzi Mucelli R

更新日期：2006-07-14 00:00:00

abstract：AIM:To analyze the current available evidence of Kudo's pit pattern classification for diagnosing colorectal neoplasms. METHODS:A search was performed on Pubmed/Embase to identify studies reporting the outcomes of the pit pattern classification in colorectal polyps. Retrieved records were evaluated and selected by two...

journal_title：World journal of gastroenterology

authors： Li M,Ali SM,Umm-a-OmarahGilani S,Liu J,Li YQ,Zuo XL

更新日期：2014-09-21 00:00:00

abstract：AIM:To describe the trend in duodenal biopsy performance during routine upper gastrointestinal endoscopy in an adult Spanish population, and to analyze its value for the diagnosis of celiac disease in clinical practice. METHODS:A 15 year-trend (1990 to 2004) in duodenal biopsy performed when undertaking upper gastroin...

journal_title：World journal of gastroenterology

authors： Riestra S,Domínguez F,Fernández-Ruiz E,García-Riesco E,Nieto R,Fernández E,Rodrigo L

更新日期：2006-08-21 00:00:00

abstract：:The search for biomarkers that characterize specific aspects of inflammatory bowel disease (IBD), has received substantial interest in the past years and is moving forward rapidly with the help of modern technologies. Nevertheless, there is a direct demand to identify adequate biomarkers for predicting and evaluating ...

journal_title：World journal of gastroenterology

authors： Quetglas EG,Mujagic Z,Wigge S,Keszthelyi D,Wachten S,Masclee A,Reinisch W

更新日期：2015-11-28 00:00:00

abstract：AIM:To clone and express the antigen of monoclonal antibody (MAb) PD4 for further investigation of its function. METHODS:MGC803 cDNA expression library was constructed and screened with PD4 as probes to clone the antigen. After failed in the library screening, immunoprecipitation and SDS-polyacrylamide gel electrophor...

journal_title：World journal of gastroenterology

authors： Ning JY,Sun GX,Huang S,Ma H,An P,Meng L,Song SM,Wu J,Shou CC

更新日期：2003-10-01 00:00:00

abstract：AIM:To investigate the safety and efficacy of the formulation HD-03/ES capsules in the management of patients with chronic hepatitis B infection. METHODS:A total of 25 patients were recruited to the study and were given HD-03/ES, two capsules twice daily for six months. Clinical assessment of symptoms and signs were d...

journal_title：World journal of gastroenterology

authors： Rajkumar JS,Sekar MG,Mitra SK

更新日期：2007-08-14 00:00:00

abstract：:Autoimmune hepatitis (AIH) is a rare chronic inflammatory disease of the liver, which affects a group of patients who lost their immunological tolerance to antigens of the liver. It is clinically characterized by hypergammaglobulinemia, elevated liver enzymes, presence of autoantibodies and histological changes. Altho...

journal_title：World journal of gastroenterology

authors： Ferri Liu PM,de Miranda DM,Fagundes ED,Ferreira AR,Simões e Silva AC

更新日期：2013-07-28 00:00:00

abstract：:The incidence of gastric cancer remains high in South Korea. Upper gastrointestinal (GI) endoscopy, i.e., esophagogastroduodenoscopy (EGD), has a higher diagnostic specificity and sensitivity than the upper GI series. Additionally, EGD has the ability to biopsy, through taking a tissue of the pathologic lesion. Succes...

journal_title：World journal of gastroenterology

authors： Lee SH,Park YK,Cho SM,Kang JK,Lee DJ

更新日期：2015-01-21 00:00:00

abstract：AIM:To investigate the mechanisms of aspirin increasing the susceptibility of Helicobacter pylori (H pylori) to metronidazole. METHODS:H pylori reference strain 26695 and two metronidazole-resistant isolates of H pylori were included in this study. Strains were incubated in Brucella broth with or without aspirin (1 mm...

journal_title：World journal of gastroenterology

authors： Zhang XP,Wang WH,Tian Y,Gao W,Li J

更新日期：2009-02-28 00:00:00

abstract：:Transient thrombocytopenia is a common phenomenon after liver transplantation. After liver transplantation (LT), platelet count decreases and reaches a nadir on postoperative days 3-5, with an average reduction in platelet counts of 60%; platelet count recovers to preoperative levels approximately two weeks after LT. ...

journal_title：World journal of gastroenterology

authors： Takahashi K,Nagai S,Safwan M,Liang C,Ohkohchi N

更新日期：2018-04-07 00:00:00

abstract：AIM:To investigate the effect of a fat rich diet on non-steroidal anti-inflammatory drug (NSAID)-induced mucosal damage in the murine small intestine. METHODS:C57BL6 mice were fed 4 types of diets with or without indomethacin. One group was fed standard laboratory chow. The other groups were fed a fat diet consisting ...

journal_title：World journal of gastroenterology

authors： Ueda T,Hokari R,Higashiyama M,Yasutake Y,Maruta K,Kurihara C,Tomita K,Komoto S,Okada Y,Watanabe C,Usui S,Nagao S,Miura S

更新日期：2015-01-07 00:00:00

abstract：AIM:To study the expression of trefoil factor 1 (TFF1) and TFF2 in precancerous condition and gastric cancer and to explore the relationship between TFFs and tumorigenesis, precancerous condition and gastric cancer. METHODS:The expression of TFF1 and TFF2 was immunohistochemically analyzed in paraffin-embedded samples...

journal_title：World journal of gastroenterology

authors： Shi SQ,Cai JT,Yang JM

更新日期：2006-05-21 00:00:00