Abstract:
AIM:To assess the utility of contrast-enhanced ultrasonography (CEUS) with a second-generation contrast medium in the differential diagnosis between mass-forming pancreatitis and pancreatic carcinoma. METHODS:From our radio-pathology database, we retrieved all the patients affected by mass-forming pancreatitis or pancreatic carcinoma who underwent CEUS. We evaluated the results of CEUS in the study of the 173 pancreatic masses considering the possibilities of a differential diagnosis between mass-forming pancreatitis and pancreatic tumor by identifying the "parenchymographic" enhancement during the dynamic phase of CEUS, which was considered diagnostic for mass-forming pancreatitis. RESULTS:At CEUS, 94% of the mass-forming pancreatitis showed intralesional parenchymography. CEUS allowed diagnosis of mass-forming pancreatitis with sensitivity of 88.6%, specificity of 97.8%, positive predictive value of 91.2%, negative predictive value of 97.1%, and overall accuracy of 96%. CEUS significantly increased the diagnostic confidence in the differential diagnosis between mass-forming pancreatitis and pancreatic carcinoma, with receiver operating characteristic curve areas from 0.557 (P = 0.1608) for baseline US to 0.956 (P < 0.0001) for CEUS. CONCLUSION:CEUS allowed diagnosis of mass-forming pancreatitis with diagnostic accuracy of 96%. CEUS significantly increases the diagnostic confidence with respect to basal US in discerning mass-forming pancreatitis from pancreatic neoplasm.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
D'Onofrio M,Zamboni G,Tognolini A,Malago R,Faccioli N,Frulloni L,Pozzi Mucelli Rdoi
10.3748/wjg.v12.i26.4181subject
Has Abstractpub_date
2006-07-14 00:00:00pages
4181-4issue
26eissn
1007-9327issn
2219-2840journal_volume
12pub_type
杂志文章abstract:AIM:To investigate the expression of tumor suppressor gene p27 and spindle checkpoint gene Mad2 and to demonstrate their expression difference in colorectal cancer and normal mucosa and to evaluate its clinical significance. METHODS:Immunohistochemical staining was used for detection of expression of Mad2 and p27 in c...
journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v10.i21.3218
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journal_title:World journal of gastroenterology
pub_type: 社论,评审
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pub_type: 社论
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doi:10.3748/wjg.v20.i1.258
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doi:10.3748/wjg.v18.i30.3997
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doi:10.3748/wjg.v22.i19.4685
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,多中心研究
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doi:10.3748/wjg.v18.i48.7319
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更新日期:2014-05-14 00:00:00
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更新日期:1999-10-01 00:00:00
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pub_type: 杂志文章
doi:10.3748/wjg.v16.i2.210
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.15.3631
更新日期:2009-08-07 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v21.i5.1675
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journal_title:World journal of gastroenterology
pub_type: 信件
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v20.i40.14904
更新日期:2014-10-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
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更新日期:2016-08-14 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v16.i17.2100
更新日期:2010-05-07 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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更新日期:2008-10-07 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,meta分析,评审
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更新日期:2015-08-21 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 临床试验,杂志文章
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更新日期:2014-12-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 临床试验,杂志文章
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更新日期:2006-09-21 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2019-09-28 00:00:00