Inhibition of hepatitis C virus replication by single-stranded RNA structural mimics.

abstract：AIM:To identify the susceptible gene (s) for type 2 diabetes in the previously mapped region, 1p36.33-p36.23, in Han population of North China using single nucleotide polymorphisms (SNPs) and to analyze the haplotypes of the gene (s) related to type 2 diabetes. METHODS:Twenty three SNPs located in 10 candidate genes i...

journal_title：World journal of gastroenterology

authors： Li YF,Sun HX,Wu GD,Du WN,Zuo J,Shen Y,Qiang BQ,Yao ZJ,Wang H,Huang W,Chen Z,Xiong MM,Meng Y,Fang FD

更新日期：2003-09-01 00:00:00

abstract：AIM:To investigate the differences in injury patterns caused by arterial, venous or arteriovenous mesenteric occlusion. METHODS:Male Wistar rats were separated equally into four groups. Occlusion was performed by clamping the superior mesenteric artery (A), the mesenteric vein (V) or both (AV) for 30 min, followed by ...

journal_title：World journal of gastroenterology

authors： Guzmán-de la Garza FJ,Cámara-Lemarroy CR,Alarcón-Galván G,Cordero-Pérez P,Muñoz-Espinosa LE,Fernández-Garza NE

更新日期：2009-08-21 00:00:00

abstract：AIM:To compare the therapeutic effects of proton pump inhibitors vs H₂ receptor antagonists for upper gastrointestinal bleeding in patients after successful endoscopy. METHODS:We searched the Cochrane library, MEDLINE, EMBASE and PubMed for randomized controlled trials until July 2014 for this study. The risk of bias ...

journal_title：World journal of gastroenterology

authors： Zhang YS,Li Q,He BS,Liu R,Li ZJ

更新日期：2015-05-28 00:00:00

abstract：:A 83-year-old woman was admitted to our hospital because of intermittent abdominal colicky pain and vomiting for 26 h. The pain localized over the periumbilical area with radiation along the medial side of the thigh. Computed tomography scan with three-dimensional reconstruction revealed a loop of small bowel protrudi...

journal_title：World journal of gastroenterology

authors： Zhang H,Cong JC,Chen CS

更新日期：2010-01-07 00:00:00

abstract：AIM:To evaluate the effect of the shunting branch of the portal vein (PV) (left or right) and the initial stent position (optimal or suboptimal) of a transjugular intrahepatic portosystemic shunt (TIPS). METHODS:We retrospectively reviewed 307 consecutive cirrhotic patients who underwent TIPS placement for variceal bl...

journal_title：World journal of gastroenterology

authors： Bai M,He CY,Qi XS,Yin ZX,Wang JH,Guo WG,Niu J,Xia JL,Zhang ZL,Larson AC,Wu KC,Fan DM,Han GH

更新日期：2014-01-21 00:00:00

abstract：:The occurrence of adult intussusception from small intestinal lymphoma is quite rare. We present an 82-year-old man with a two-month history of intermittent abdominal pain, nausea and fatigue. Clinical symptoms included moderate abdominal tenderness in the right lower abdomen. Computed tomography scan of the abdomen r...

journal_title：World journal of gastroenterology

authors： Xu XQ,Hong T,Li BL,Liu W

更新日期：2013-12-07 00:00:00

abstract：:The normal esophageal mucosa creates a protective epithelial barrier that constrains the acidic reflux in the esophageal lumen. Microscopic findings and functional studies indicate that this barrier might be impaired in patients with non erosive reflux disease (NERD) but not in patients with functional heartburn (FH)....

journal_title：World journal of gastroenterology

authors： Triantos C,Koukias N,Karamanolis G,Thomopoulos K

更新日期：2015-05-21 00:00:00

abstract：AIM:To detect the anomaly in the persistent right umbilical vein (PRUV) of portal vein (PV) with deviation of the ligamentum tere and left-sided gallbladder. METHODS:A total of 5783 candidates for routine analysis were evaluated for hepatic vascular abnormalities by ultrasonography. RESULTS:Ten candidates (0.17%) had...

journal_title：World journal of gastroenterology

authors： Nakanishi S,Shiraki K,Yamamoto K,Koyama M,Nakano T

更新日期：2005-02-28 00:00:00

abstract：AIM:To evaluate safety and effect on hepatitis B virus (HBV) suppression of a long-term treatment with lamivudine (LAM) at standard (100 mg/d) or double (200 mg/d) dose in chronic hepatitis B. METHODS:This was a case study with matched controls (1:3) in patients with chronic hepatitis B with anti-HBe antibodies. RESU...

journal_title：World journal of gastroenterology

authors： Stornaiuolo G,Stanzione M,Brancaccio G,Cuomo G,Precone V,Di Biase S,Felaco FM,Piccinino F,Gaeta GB

更新日期：2007-11-14 00:00:00

abstract：:Proteus syndrome is an extremely rare congenital disorder that produces multifocal overgrowth of tissue. This report presents a surgical case of a large lipoma in the abdominal wall of a patient with Proteus syndrome. She was diagnosed with Proteus syndrome based on certain diagnostic criteria. The neoplasm increased ...

journal_title：World journal of gastroenterology

authors： Nakayama Y,Kusuda S,Nagata N,Yamaguchi K

更新日期：2009-07-14 00:00:00

abstract：AIM:To evaluate the safety of lamivudine (LAM) treatment for chronic hepatitis B in early pregnancy. METHODS:A total of 92 pregnant women who received LAM treatment either before pregnancy or in early pregnancy were enrolled in this study. All of the pregnant women volunteered to take lamivudine during pregnancy and w...

journal_title：World journal of gastroenterology

authors： Yi W,Liu M,Cai HD

更新日期：2012-12-07 00:00:00

abstract：:Non-HFE hereditary haemochromatosis (HH) refers to a genetically heterogeneous group of iron overload disorders that are unlinked to mutations in the HFE gene. The four main types of non-HFE HH are caused by mutations in the hemojuvelin, hepcidin, transferrin receptor 2 and ferroportin genes. Juvenile haemochromatosis...

journal_title：World journal of gastroenterology

authors： Wallace DF,Subramaniam VN

更新日期：2007-09-21 00:00:00

abstract：:The prevalence of non-alcoholic fatty liver disease (NAFLD) is rising exponentially worldwide. The spectrum of NAFLD includes non-alcoholic fatty liver, non-alcoholic steatohepatitis, liver cirrhosis, and even hepatocellular carcinoma. Evidence shows that microbial metabolites play pivotal roles in the onset and progr...

journal_title：World journal of gastroenterology

authors： Zhou D,Fan JG

更新日期：2019-05-07 00:00:00

abstract：BACKGROUND:Computed tomography (CT), liver stiffness measurement (LSM), and magnetic resonance imaging (MRI) are non-invasive diagnostic methods for esophageal varices (EV) and for the prediction of high-bleeding-risk EV (HREV) in cirrhotic patients. However, the clinical use of these methods is controversial. AIM:To ...

journal_title：World journal of gastroenterology

authors： Li Y,Li L,Weng HL,Liebe R,Ding HG

更新日期：2020-05-14 00:00:00

abstract：AIM:To investigate the fluid shear stress induced changes of (Ca(2+))i in neutrophils in pancreatic microcirculation of experimental acute pancreatitis (AP). METHODS:Wistar rats (n = 36) were randomized into three groups. A model of AP was established by subcutaneous injection of caerulein. Low-shear 30 viscometer was...

journal_title：World journal of gastroenterology

authors： Zhou ZG,Chen YQ,Liu XB,Hu WM,Tian BL,Chen HQ

更新日期：2004-11-01 00:00:00

abstract：:In order to have an adequate view of the whole small intestine during capsule endoscopy, the preparation recommended consists of a clear liquid diet and an overnight fast. However, visualization of the small bowel during video capsule endoscopy can be impaired by intestinal contents. To improve mucosal visualization, ...

journal_title：World journal of gastroenterology

authors： Pons Beltrán V,Carretero C,Gonzalez-Suárez B,Fernandez-Urien I,Muñoz-Navas M

更新日期：2008-10-07 00:00:00

abstract：:Gastrointestinal cancers represent a major cause of morbidity and mortality, with incomplete response to chemotherapy in the advanced stages and poor prognosis. Angiogenesis plays a crucial part in tumor growth and metastasis, with most gastrointestinal cancers depending strictly on the development of a new and devote...

journal_title：World journal of gastroenterology

authors： Gheonea DI,Cârţână T,Ciurea T,Popescu C,Bădărău A,Săftoiu A

更新日期：2011-01-07 00:00:00

abstract：:We have described a previously unreported entity of an intussuscepted neuroendocrine carcinoma of the appendix. Our patient was a 70-year-old man whose only complaint was insipient weight loss. Colonoscopy showed a malignant cecal "polyp", and an extended right hemicolectomy was performed. We have reviewed the literat...

journal_title：World journal of gastroenterology

authors： Thomas RE,Maude K,Rotimi O

更新日期：2006-02-14 00:00:00

abstract：AIM:To detect the prevalence of small bowel polyps by wireless capsule endoscopy (WCE) in patients with familial adenomatous polyposis (FAP). METHODS:We examined prospectively 14 patients with FAP to assess the location, size and number of small-intestinal polyps. Patients' age, sex, years of observation after surgery...

journal_title：World journal of gastroenterology

authors： Katsinelos P,Kountouras J,Chatzimavroudis G,Zavos C,Pilpilidis I,Fasoulas K,Paroutoglou G

更新日期：2009-12-28 00:00:00

abstract：AIM:To investigate the effects and mechanisms of melatonin on immunological liver injury in mice. METHODS:A model of liver injury was induced by tail vein injection of Bacillus Calmette Guerin (BCG) and lipopolysaccharide (LPS) in mice. Kupffer cells and hepatocytes were isolated and cultured according to a modified t...

journal_title：World journal of gastroenterology

authors： Wang H,Wei W,Shen YX,Dong C,Zhang LL,Wang NP,Yue L,Xu SY

更新日期：2004-09-15 00:00:00

abstract：:Patients with advanced gastric cancer (AGC) can be treated with multiple lines of chemotherapy. Although several randomized trials have demonstrated the benefit of second-line chemotherapy compared with best supportive care, there is no evidence that further lines of chemotherapy will result in substantial prolongatio...

journal_title：World journal of gastroenterology

authors： Kim SM,Park SH

更新日期：2015-08-07 00:00:00

abstract：AIM:To elucidate the relationship between the microvessel count (MVC) by CD34 analyzed by immunohistochemical method and prognosis in hepatocellular carcinoma (HCC) patients who underwent hepatectomy based on our preliminary study. METHODS:We examined relationships between MVC and clinicopathological factors in 128 HC...

journal_title：World journal of gastroenterology

authors： Nanashima A,Nakayama T,Sumida Y,Abo T,Takeshita H,Shibata K,Hidaka S,Sawai T,Yasutake T,Nagayasu T

更新日期：2008-08-21 00:00:00

abstract：AIM:To evaluate the feasibility of using multiphoton microscopy (MPM) to assess a tumor regression grading (TRG) system. METHODS:Fresh specimens from seven patients with colorectal carcinoma undergoing neoadjuvant radiochemotherapy at the Fujian Medical University Union Hospital were obtained immediately after proctec...

journal_title：World journal of gastroenterology

authors： Li LH,Chen ZF,Wang XF,Zhuo SM,Li HS,Jiang WZ,Guan GX,Chen JX

更新日期：2015-04-14 00:00:00

abstract：:Celiac disease (CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. The disease is featured by a variable combination of clinical signs, specific antibodies, HLA-DQ2 and HLA-DQ8 haplotypes, and enteropathy. Vaccination is the most poten...

journal_title：World journal of gastroenterology

authors： Anania C,Olivero F,Spagnolo A,Chiesa C,Pacifico L

更新日期：2017-05-14 00:00:00

abstract：AIM:Heat shock protein (HSP)70 is over-expressed in human gastric cancer and plays an important role in the progression of this cancer. We investigated the effects of antisense HSP70 oligomer on human gastric cancer cell line SGC-7901, and its potential role in gene therapy for this cancer. METHODS:Human gastric cance...

journal_title：World journal of gastroenterology

authors： Zhao ZG,Shen WL

更新日期：2005-01-07 00:00:00

abstract：AIM:To check the efficacy of the PERFACT procedure in highly complex fistula-in-ano. METHODS:The PERFACT procedure (proximal superficial cauterization, emptying regularly fistula tracts and curettage of tracts) entails two steps: superficial cauterization of mucosa at and around the internal opening and keeping all th...

journal_title：World journal of gastroenterology

authors： Garg P,Garg M

更新日期：2015-04-07 00:00:00

abstract：AIM:To study the inhibitory effect of mononuclear bone marrow cell (BMC) transplantation on carbon tetrachloride (CCl(4)) -induced liver fibrosis in rats. METHODS:Rat liver fibrosis models were induced by CCl(4) and alcohol administration. After 8 wk, twenty rats were randomly allocated into treatment group (n = 10) a...

journal_title：World journal of gastroenterology

authors： Cao BQ,Lin JZ,Zhong YS,Huang SB,Lin N,Tang ZF,Chen R,Xiang P,Xu RY

更新日期：2007-03-28 00:00:00

abstract：AIM:To investigate whether the apoptotic activities of 8-bromo-7-methoxychrysin (BrMC) involve reactive oxygen species (ROS) generation and c-Jun N-terminal kinase (JNK) activation in human hepatocellular carcinoma cells (HCC). METHODS:HepG2, Bel-7402 and L-02 cell lines were cultured in vitro and the apoptotic effect...

journal_title：World journal of gastroenterology

authors： Yang XH,Zheng X,Cao JG,Xiang HL,Liu F,Lv Y

更新日期：2010-07-21 00:00:00

abstract：AIM:To develop a novel method for the rapid and efficient extraction of exosomes secreted by tumor cells. METHODS:Unlike the traditional extraction method, the supernatants of cell cultures were concentrated, and the exosomes were isolated promptly and effectively using a novel nanomaterial called ExoQuick. Coomassie ...

journal_title：World journal of gastroenterology

authors： Zhu L,Qu XH,Sun YL,Qian YM,Zhao XH

更新日期：2014-06-07 00:00:00

abstract：AIM:To investigate the relationship of changes in expression of marker genes in functional categories or molecular networks comprising one functional category or multiple categories in progression of hepatic fibrosis in hepatitis C (HCV) patients. METHODS:Marker genes were initially identified using DNA microarray dat...

journal_title：World journal of gastroenterology

authors： Takahara Y,Takahashi M,Zhang QW,Wagatsuma H,Mori M,Tamori A,Shiomi S,Nishiguchi S

更新日期：2008-04-07 00:00:00