Microbial metabolites in non-alcoholic fatty liver disease.

Abstract:

:The prevalence of non-alcoholic fatty liver disease (NAFLD) is rising exponentially worldwide. The spectrum of NAFLD includes non-alcoholic fatty liver, non-alcoholic steatohepatitis, liver cirrhosis, and even hepatocellular carcinoma. Evidence shows that microbial metabolites play pivotal roles in the onset and progression of NAFLD. In this review, we discuss how microbe-derived metabolites, such as short-chain fatty acids, endogenous ethanol, bile acids and so forth, contribute to the pathogenesis of NAFLD.

journal_name

World J Gastroenterol

authors

Zhou D,Fan JG

doi

10.3748/wjg.v25.i17.2019

subject

Has Abstract

pub_date

2019-05-07 00:00:00

pages

2019-2028

issue

17

eissn

1007-9327

issn

2219-2840

journal_volume

25

pub_type

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