Wireless capsule endoscopy in detecting small-intestinal polyps in familial adenomatous polyposis.

Abstract:

AIM:To detect the prevalence of small bowel polyps by wireless capsule endoscopy (WCE) in patients with familial adenomatous polyposis (FAP). METHODS:We examined prospectively 14 patients with FAP to assess the location, size and number of small-intestinal polyps. Patients' age, sex, years of observation after surgery, type of surgery, duodenal polyps and colorectal cancer at surgery were analyzed. RESULTS:During WCE, polyps were detected in 9/14 (64.3%) patients. Duodenal adenomatous polyps were found in nine (64.3%) patients, and jejunal and ileal polyps in seven (50%) and eight (57.1%), respectively. The Spigelman stage of duodenal polyposis was associated with the presence of jejunal and ileal polyps. Identification of the ampulla of Vater was not achieved with WCE. Importantly, the findings of WCE had no immediate impact on the further clinical management of FAP patients. No procedure-related complications were observed in the patients. CONCLUSION:WCE is a promising noninvasive new method for the detection of small-intestinal polyps. Further investigation is required to determine which phenotype of FAP is needed for surveillance with WCE.

journal_name

World J Gastroenterol

authors

Katsinelos P,Kountouras J,Chatzimavroudis G,Zavos C,Pilpilidis I,Fasoulas K,Paroutoglou G

doi

10.3748/wjg.15.6075

subject

Has Abstract

pub_date

2009-12-28 00:00:00

pages

6075-9

issue

48

eissn

1007-9327

issn

2219-2840

journal_volume

15

pub_type

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