Abstract:
:Alverine citrate is a commonly used smooth muscle relaxant agent. A MEDLINE search on January 2004 revealed only 1 report implicating the hepatotoxicity of this agent. A 34-year-old woman was investigated because of the finding of elevated liver function tests on biochemical screening. Other etiologies of hepatitis were appropriately ruled out and elevated enzymes were ascribed to alverine citrate treatment. Although alverine citrate hepatotoxicity was related to an immune mechanism in the first case, several features such as absence of predictable dose-dependent toxicity of alverine citrate in a previous study and absence of hypersensitivity manifestations in our patient are suggestive of a metabolic type of idiosyncratic toxicity.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Arhan M,Koklu S,Koksal AS,Yolcu OF,Koruk S,Koruk I,Kayacetin Edoi
10.3748/wjg.v10.i15.2303keywords:
subject
Has Abstractpub_date
2004-08-01 00:00:00pages
2303-4issue
15eissn
1007-9327issn
2219-2840journal_volume
10pub_type
杂志文章abstract::A variety of hepatic and biliary tract disorders may complicate the clinical course of celiac disease. Some of these have been hypothesized to share common genetic factors or have a common immunopathogenesis, such as primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune forms of hepatitis or cholang...
journal_title:World journal of gastroenterology
pub_type: 社论,评审
doi:10.3748/wjg.v12.i10.1503
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journal_title:World journal of gastroenterology
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pub_type: 杂志文章,meta分析
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journal_title:World journal of gastroenterology
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doi:10.3748/wjg.v4.i1.18
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journal_title:World journal of gastroenterology
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pub_type: 杂志文章
doi:10.3748/wjg.v12.i10.1577
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v13.i9.1449
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pub_type: 杂志文章,评审
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.v12.i20.3265
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pub_type: 杂志文章
doi:10.3748/wjg.v16.i23.2926
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journal_title:World journal of gastroenterology
pub_type: 评论,信件
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pub_type: 杂志文章
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pub_type: 社论,评审
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.14.574
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v20.i1.326
更新日期:2014-01-07 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v19.i32.5278
更新日期:2013-08-28 00:00:00
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.v21.i10.2926
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pub_type: 杂志文章,评审
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
doi:10.3748/wjg.14.3328
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
doi:10.3748/wjg.14.6881
更新日期:2008-11-28 00:00:00
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pub_type: 社论,评审
doi:10.3748/wjg.v17.i15.1927
更新日期:2011-04-21 00:00:00