Expression and location of Smad2, 4 mRNAs during and after liver fibrogenesis of rats.

abstract：AIM:To examine the effect of Fusobacterium nucleatum (F. nucleatum) on the microenvironment of colonic neoplasms and the expression of inflammatory mediators and microRNAs (miRNAs). METHODS:Levels of F. nucleatum DNA, cytokine gene mRNA (TLR2, TLR4, NFKB1, TNF, IL1B, IL6 and IL8), and potentially interacting miRNAs (m...

journal_title：World journal of gastroenterology

authors： Proença MA,Biselli JM,Succi M,Severino FE,Berardinelli GN,Caetano A,Reis RM,Hughes DJ,Silva AE

更新日期：2018-12-21 00:00:00

abstract：AIM:To analyze the available evidence about the risk of extrapancreatic malignancies and pancreatic ductal adenocarcinoma associated to pancreatic intraductal papillary mucinous tumors (IPMNs). METHODS:A systematic search of literature was undertaken using MEDLINE, EMBASE, Cochrane and Web-of-Science libraries. No lim...

journal_title：World journal of gastroenterology

authors： Baiocchi GL,Molfino S,Frittoli B,Pigozzi G,Gheza F,Gaverini G,Tarasconi A,Ricci C,Bertagna F,Grazioli L,Tiberio GA,Portolani N

更新日期：2015-06-21 00:00:00

abstract：:We have read with interest the paper by Roman C. and colleagues discussing the relationship between gastroesophageal reflux disease and atrial fibrillation. The review is presenting the available evidence for the common pathogenic mechanisms. However, from a cardiologist perspective, some available data were not highl...

journal_title：World journal of gastroenterology

authors： Floria M,Drug VL

更新日期：2015-03-14 00:00:00

abstract：:Gastric intramural hematoma is a rare injury of the stomach, and is most often seen in patients with underlying disease. Such injury following endoscopic therapy is even rarer, and there are no universally accepted guidelines for its treatment. In this case report, we describe a gastric intramural hematoma which occur...

journal_title：World journal of gastroenterology

authors： Sun P,Tan SY,Liao GH

更新日期：2012-12-21 00:00:00

abstract：:Hepatic encephalopathy (HE) is a neuropsychiatric complication of cirrhosis or acute liver failure. Currently, HE is regarded as a continuous cognitive impairment ranging from the mildest stage, minimal HE to overt HE. Hyperammonaemia and neuroinflammation are two main underlying factors which contribute to the neurol...

journal_title：World journal of gastroenterology

authors： Zhang XD,Zhang LJ,Wu SY,Lu GM

更新日期：2014-08-28 00:00:00

abstract：AIM:To present our experience with tuberculous peritonitis treated in our hospital from 2002-2007. METHODS:We reviewed the medical records of 9 children with tuberculous peritonitis. RESULTS:Nine patients (5 boys, 4 girls) of mean age 14.2 years were diagnosed with peritoneal tuberculosis. All patients presented with...

journal_title：World journal of gastroenterology

authors： Dinler G,Sensoy G,Helek D,Kalayci AG

更新日期：2008-12-21 00:00:00

abstract：AIM:To determine whether local antibiotic resistance involves P-glycoprotein (Pgp)-mediated active drug out-pumping during Helicobacter pylori (H pylori) infection treatment with classic antibiotic therapy. METHODS:Pgp activity was determined in gastric mucosa biopsy specimens obtained from 53 patients with pathohisto...

journal_title：World journal of gastroenterology

authors： Babic Z,Svoboda-Beusan I,Kucisec-Tepes N,Dekaris D,Troskot R

更新日期：2005-05-14 00:00:00

abstract：AIM:To investigate disease-specific gene expression profiles of peripheral blood mononuclear cells (PBMCs) from Crohn's disease (CD) patients in clinical remission. METHODS:Patients with CD in clinical remission or with very low disease activity according to the Crohn's disease activity index were genotyped regarding ...

journal_title：World journal of gastroenterology

authors： Schäffler H,Rohde M,Rohde S,Huth A,Gittel N,Hollborn H,Koczan D,Glass Ä,Lamprecht G,Jaster R

更新日期：2018-03-21 00:00:00

abstract：:We report a unique case of intramucosal carcinoma in a tubulovillous adenoma arising from a single diverticulum. Endoscopic mucosal resection (EMR) was carried out successfully and completely with the assistance of laparoscopy. A 71-year-old man was admitted to our hospital because of melena and anemia. Emergent colon...

journal_title：World journal of gastroenterology

authors： Fu KI,Hamahata Y,Tsujinaka Y

更新日期：2010-03-28 00:00:00

abstract：:Chronic radiation proctopathy occurs in 5%-20% of patients following pelvic radiotherapy. Although many cases resolve spontaneously, some lead to chronic symptoms including diarrhea, tenesmus, urgency and persistent rectal bleeding with iron deficiency anemia requiring blood transfusions. Treatments for chronic radiat...

journal_title：World journal of gastroenterology

authors： Rustagi T,Mashimo H

更新日期：2011-11-07 00:00:00

abstract：AIM:To investigate the rate of Helicobacter pylori (H. pylori) resistance to clarithromycin among ethnic minority patients in Guangxi, explore the underlying mechanisms, and analyze factors influencing genotype distribution of H. pylori isolates. METHODS:H. pylori strains were isolated, cultured and subjected to drug ...

journal_title：World journal of gastroenterology

authors： Zhao LJ,Huang YQ,Chen BP,Mo XQ,Huang ZS,Huang XF,Wei LD,Wei HY,Chen YH,Tang HY,Huang GR,Qin YC,Li XH,Wang LY

更新日期：2014-04-28 00:00:00

abstract：AIM:To evaluate the protective effect and mechanism of glutamine on the intestinal barrier function in total parenteral nutrition (TPN) rats with trauma or endotoxemia. METHODS:To perform prospective, randomized and controlled animal experimentation of rats with surgical trauma, TPN and endotoxemia, thirty-four male, ...

journal_title：World journal of gastroenterology

authors： Ding LA,Li JS

更新日期：2003-06-01 00:00:00

abstract：AIM:To study the role of gastric mucosal ascorbic acid (AA) in the progression of acute gastric mucosal lesions induced by compound 48/80 (C48/80), a mast cell degranulator, in rats. METHODS:C48/80 (0.75 mg/kg) was intraperitoneally injected to fasted Wistar rats. Oral administration of AA (10, 50 or 100 mg/kg) was pe...

journal_title：World journal of gastroenterology

authors： Kamiya Y,Ohta Y,Imai Y,Arisawa T,Nakano H

更新日期：2005-03-07 00:00:00

abstract：AIM:To explore the relationship between dynamic expression of high mobility group box-3 (HMGB3) and malignant transformation of hepatocytes. METHODS:Expression of HMGB family proteins were observed in rat hepatocarcinogenesis models induced with 2-acetylaminofluorene. Alterations of HMGB3 were analyzed at the mRNA lev...

journal_title：World journal of gastroenterology

authors： Zheng WJ,Yao M,Fang M,Wang L,Dong ZZ,Yao DF

更新日期：2018-08-28 00:00:00

abstract：AIM:Hepatitis B virus (HBV) re-activation often occurs spontaneously or after withdrawal of immunosuppressive therapy in patients with chronic hepatitis B. Severe exacerbation, sometimes developing into fulminant hepatic failure, is at high risk of mortality. The efficacy of corticosteroid therapy in "clinically severe...

journal_title：World journal of gastroenterology

authors： Fujiwara K,Yokosuka O,Kojima H,Kanda T,Saisho H,Hirasawa H,Suzuki H

更新日期：2005-02-28 00:00:00

abstract：:We report a case of two pseudolymphomas of the liver in a 63-year-old Japanese woman with primary biliary cirrhosis. One of the lesions was found incidentally during a medical examination, presenting as a 10 mm hypodense nodule that revealed hyperdensity in the early phase and hypodensity in the late phase in computed...

journal_title：World journal of gastroenterology

authors： Okada T,Mibayashi H,Hasatani K,Hayashi Y,Tsuji S,Kaneko Y,Yoshimitsu M,Tani T,Zen Y,Yamagishi M

更新日期：2009-09-28 00:00:00

abstract：BACKGROUND:Understanding the treatment landscape of inflammatory bowel diseases (IBD) is essential for improving disease management and patient outcomes. Brazil is the largest Latin American country, and it presents socioeconomic and health care differences across its geographical regions. This country has the highest ...

journal_title：World journal of gastroenterology

authors： Zaltman C,Parra RS,Sassaki LY,Santana GO,Ferrari MLA,Miszputen SJ,Amarante HMBS,Kaiser Junior RL,Flores C,Catapani WR,Parente JML,Bafutto M,Ramos O,Gonçalves CD,Guimaraes IM,da Rocha JJR,Feitosa MR,Feres O,Saad-Hossne

更新日期：2021-01-14 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer and has a 5-year survival of < 5%. Only about 15% of the patients present with a resectable PDAC with potential to undergo "curative" surgery. After surgery, local and systemic recurrence, is though very common. The median survival ...

journal_title：World journal of gastroenterology

authors： Ansari D,Gustafsson A,Andersson R

更新日期：2015-03-21 00:00:00

abstract：BACKGROUND:Autophagy is an evolutionarily conserved biological process in eukaryotic cells that involves lysosomal-mediated degradation and recycling of related cellular components. Recent studies have shown that autophagy plays an important role in the pathogenesis of Crohn's disease (CD). Herbal cake-partitioned moxi...

journal_title：World journal of gastroenterology

authors： Wang SY,Zhao JM,Zhou CL,Zheng HD,Huang Y,Zhao M,Zhang ZY,Wu LY,Wu HG,Liu HR

更新日期：2020-10-21 00:00:00

abstract：AIM:To investigate the predictive clinical value of in vitro 3-(4,5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide (MTT) assay for directing chemosensitivity in patients with gastric cancer. METHODS:Results of a total of 353 consecutive patients with gastric cancer treated with MTT-directed chemotherapy or phys...

journal_title：World journal of gastroenterology

authors： Wu B,Zhu JS,Zhang Y,Shen WM,Zhang Q

更新日期：2008-05-21 00:00:00

abstract：AIM:To evaluate a laparoscopic approach to gallbladder lesions including polyps, wall-thickening lesions, and suspected T1 and T2 gallbladder cancer (GBC). METHODS:We performed 50 cases of laparoscopic whole-layer cholecystectomy (LCWL) and 13 cases of laparoscopic gallbladder bed resection (LCGB) for those gallbladde...

journal_title：World journal of gastroenterology

authors： Ome Y,Hashida K,Yokota M,Nagahisa Y,Okabe M,Kawamoto K

更新日期：2017-04-14 00:00:00

abstract：AIM:To identify preoperative predictive factors associated with malignancy of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. METHODS:Between April 1995 and April 2010, 129 patients underwent surgical resection for IPMNs at our institute and had confirmed pathologic diagnoses. The medical records wer...

journal_title：World journal of gastroenterology

authors： Lee JH,Lee KT,Park J,Bae SY,Lee KH,Lee JK,Jang KT,Heo JS,Choi SH,Choi DW,Rhee JC

更新日期：2010-11-14 00:00:00

abstract：:Weight loss supplements often contain powerful pharmacoactive ingredients with the potential to cause harm. Trials used to determine product safety and effectiveness, meanwhile, tend to be small, of short duration, and frequently lack financial conflict of interest disclosures. These factors could conspire to place co...

journal_title：World journal of gastroenterology

authors： Lobb A

更新日期：2010-10-14 00:00:00

abstract：AIM:To explore the mode of inheritance of hepatocellular carcinoma (HCC) in a moderately high-incidence area of East China. METHODS:A pedigree survey was conducted in 210 families (3315 individuals) ascertained through 210 HCC probands in Haimen, Jiangsu Province. Simple segregation analysis was conducted using SEGRAN...

journal_title：World journal of gastroenterology

authors： Cai RL,Meng W,Lu HY,Lin WY,Jiang F,Shen FM

更新日期：2003-11-01 00:00:00

abstract：:Alterations of normal function of interstitial cells of Cajal (ICC) are reported in many intestinal disorders. Diagnosis of their involvement is rare (infrequent), but necessary to propose a specific treatment. This article reviews the place of ICC in the pathogenesis of achalasia, gastroesophageal reflux disease, inf...

journal_title：World journal of gastroenterology

authors： Negreanu LM,Assor P,Mateescu B,Cirstoiu C

更新日期：2008-11-07 00:00:00

abstract：AIM:To observe the frequent complications of stent placement for stricture of the gastrointestinal tract and to find proper treatment. METHODS:A total number of 140 stents were inserted in 138 patients with benign stricture of the gastrointestinal tract. The procedure was completed under fluoroscopy in all of the pati...

journal_title：World journal of gastroenterology

authors： Cheng YS,Li MH,Chen WX,Chen NW,Zhuang QX,Shang KZ

更新日期：2004-01-15 00:00:00

abstract：AIM:To investigate the role of nuclear factor-kappaB (NF-kappaB) inhibitor caffeic acid phenethy1 ester (CAPE) in the proliferation, collagen synthesis and apoptosis of hepatic stellate cells (HSCs) of rats. METHODS:The HSCs from rats were isolated and cultured in Dulbecco's Modified Eagle's Medium (DMEM) and treated ...

journal_title：World journal of gastroenterology

authors： Zhao WX,Zhao J,Liang CL,Zhao B,Pang RQ,Pan XH

更新日期：2003-06-01 00:00:00

abstract：AIM:To investigate a suitable long-term culture system and optimal cryopreservation of intestinal organoid to improve organoid-based therapy by acquiring large numbers of cells. METHODS:Crypts were isolated from jejunum of C57BL/6 mouse. Two hundred crypts were cultured in organoid medium with either epidermal growth ...

journal_title：World journal of gastroenterology

authors： Han SH,Shim S,Kim MJ,Shin HY,Jang WS,Lee SJ,Jin YW,Lee SS,Lee SB,Park S

更新日期：2017-02-14 00:00:00

abstract：AIM:To detect the expression of DPC4 in malignant and non-malignant specimens of human pancreas, and observe the inhibition of retroviral pLXSN containing DPC4 on pancreatic carcinoma cells in vitro. METHODS:The expression of DPC4 was determined in 40 pancreatic adenocarcinoma and 36 non-malignant pancreatic specimens...

journal_title：World journal of gastroenterology

authors： Shen W,Tao GQ,Li DC,Zhu XG,Bai X,Cai B

更新日期：2008-10-28 00:00:00

abstract：AIM:To study the inhibitory effects of a Shuangling Fuzheng anticancer preparation (SFAP) on the human gastric cancer cell line SGC-7901 in vitro as well as its immune-modulated effects in a cyclophosphamide-treated murine model. METHODS:MTT experiments and immunocytochemistry ABC experiments were performed for detect...

journal_title：World journal of gastroenterology

authors： Chen HS,Chen J,Cui DL,Zheng YY,Xu AH,Chen G,Jia LC

更新日期：2007-12-28 00:00:00