Segregation analysis of hepatocellular carcinoma in a moderately high-incidence area of East China.

abstract：:Following the international guidelines criteria an adequate "diagnostic conclusion" of inflammatory bowel disease (IBD) can be achieved only if clinical, endoscopic and laboratory findings, together with sample technical adequacy and unequivocal histomorphological signs of the disease are available. Thus, a conclusive...

journal_title：World journal of gastroenterology

authors： Canavese G,Bassotti G,Astegiano M,Castellano I,Cassoni P,Sapino A,Villanacci V

更新日期：2013-01-21 00:00:00

abstract：AIM:To investigate the expression of cancer related genes in gastric carcinoma (GC) through the use of Atlas Human Cancer Array membranes with 588 well-characterized human genes related to cancer and tumor biology. METHODS:Hybridization of cDNA blotting membrane was performed with (32)P-labeled cDNA probes synthesized...

journal_title：World journal of gastroenterology

authors： Liu LX,Liu ZH,Jiang HC,Qu X,Zhang WH,Wu LF,Zhu AL,Wang XQ,Wu M

更新日期：2002-08-01 00:00:00

abstract：AIM:To observe the kinetics of D (-)-lactate alteration in both portal and systemic circulation systems, and its relationship with intestinal injury in rats subjected to acute intestinal ischemia-reperfusion. METHODS:Anesthetized rats underwent a 75-min superior mesenteric artery occlusion followed by a 6-h reperfusio...

journal_title：World journal of gastroenterology

authors： Yao YM,Yu Y,Wu Y,Lu LR,Sheng ZY

更新日期：1997-12-15 00:00:00

abstract：AIM:To investigate the characteristic radiologic findings of cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) which can be differentiated from other similar bowel disease and to assess their clinical behavior. METHODS:Twenty pathologically and clinically confirmed CMUSE patients (males:females = 8:12; mean ...

journal_title：World journal of gastroenterology

authors： Hwang J,Kim JS,Kim AY,Lim JS,Kim SH,Kim MJ,Kim MS,Song KD,Woo JY

更新日期：2017-07-07 00:00:00

abstract：AIM:To examine the effects of combined treatment of oxaliplatin and phosphatidylinositol 3'-kinase inhibitor, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) for gastric cancer. METHODS:Cell viability was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Apoptotic cells were ...

journal_title：World journal of gastroenterology

authors： Liu J,Fu XQ,Zhou W,Yu HG,Yu JP,Luo HS

更新日期：2011-01-14 00:00:00

abstract：:Primary sclerosing cholangitis (PSC) is a disease of the biliary tract, which has been documented in the literature since 1867. This disease has a strong predilection for affecting men and can be seen in individuals as young as 2 years of age. PSC has a strong associated with inflammatory bowel disease, more commonly ...

journal_title：World journal of gastroenterology

authors： Gidwaney NG,Pawa S,Das KM

更新日期：2017-04-14 00:00:00

abstract：AIM:To establish the therapeutic potential of proteasome inhibition, we examined the therapeutic effects of MG132 (Z-Leu-Leu-Leu-aldehyde) in an experimental model of acute pancreatitis. METHODS:Pancreatitis was induced in rats by two hourly intraperitoneal (ip) injections of cholecystokinin octapeptide (CCK; 2 x 100 ...

journal_title：World journal of gastroenterology

authors： Letoha T,Fehér LZ,Pecze L,Somlai C,Varga I,Kaszaki J,Tóth G,Vizler C,Tiszlavicz L,Takács T

更新日期：2007-09-07 00:00:00

abstract：AIM:To elucidate the role and alterations of syndecan-1 and E-cadherin expression in different cellular phenotypes of differentiated-type gastric cancers (DGCs). METHODS:A total of 120 DGCs at an early stage, and their adjacent mucosa, were studied both by immunohistochemistry. Syndecan-1 and E-cadherin were assessed ...

journal_title：World journal of gastroenterology

authors： Huang MF,Zhu YQ,Chen ZF,Xiao J,Huang X,Xiong YY,Yang GF

更新日期：2005-05-21 00:00:00

abstract：AIM:To evaluate the risk factors for ampullary adenoma and ampullary cancer. METHODS:This case-control study included ampullary tumor patients referred to Peking Union Medical College Hospital. Controls were randomly selected from an existing database of healthy individuals at the Health Screening Center of the same h...

journal_title：World journal of gastroenterology

authors： He XD,Wu Q,Liu W,Hong T,Li JJ,Miao RY,Zhao HT

更新日期：2014-07-28 00:00:00

abstract：BACKGROUND:Acute severe ulcerative colitis unresponsive to systemic steroid treatment is a life-threatening medical condition requiring hospitalization and often colectomy. Despite the increasing choice of medical therapy options for ulcerative colitis, the condition remains a great challenge in the field of inflammato...

journal_title：World journal of gastroenterology

authors： Hoffmann P,Wehling C,Krisam J,Pfeiffenberger J,Belling N,Gauss A

更新日期：2019-04-07 00:00:00

abstract：AIM:To describe the learning curves of hand-assisted laparoscopic D2 radical gastrectomy (HALG) for the treatment of gastric cancer. METHODS:The HALG surgical procedure consists of three stages: surgery under direct vision via the port for hand assistance, hand-assisted laparoscopic surgery, and gastrointestinal tract...

journal_title：World journal of gastroenterology

authors： Gong JQ,Cao YK,Wang YH,Zhang GH,Wang PH,Luo GD

更新日期：2015-02-07 00:00:00

abstract：:Gastric cancer and liver cancer are among the most common malignancies and the leading causes of death worldwide, due to late detection and high recurrence rates. Today, these cancers have a heavy socioeconomic burden, for which a full understanding of their pathophysiological features is warranted to search for promi...

journal_title：World journal of gastroenterology

authors： Cao DX,Li ZJ,Jiang XO,Lum YL,Khin E,Lee NP,Wu GH,Luk JM

更新日期：2012-08-14 00:00:00

abstract：AIM:To describe the bowel habits and the prevalence of irritable bowel syndrome (IBS) and to investigate the influence of health behavior and social factors on IBS prevalence in university students. METHODS:This cross-sectional study was conducted at five major universities in Greater Beirut and its suburbs, between F...

journal_title：World journal of gastroenterology

authors： Costanian C,Tamim H,Assaad S

更新日期：2015-03-28 00:00:00

abstract：AIM:To determine whether any changes have occurred on the patterns of colorectal cancer in China. METHODS:Data from 21 Chinese articles published from 1980 to 1999, were used to analyze the time trend of colorectal cancer according to the patients' age at diagnosis, sex, the site of the tumor, stage, and the pathology...

journal_title：World journal of gastroenterology

authors： Li M,Gu J

更新日期：2005-08-14 00:00:00

abstract：AIM:To investigate the prognostic value of vascular endothelial growth factor messenger RNA (VEGF mRNA) in the peripheral blood (PB) of patients with hepatocellular carcinoma (HCC) undergoing curative resection. METHODS:Using a reverse-transcription polymerase chain reaction (RT-PCR)-based assay, VEGF mRNA in the PB w...

journal_title：World journal of gastroenterology

authors： Jeng KS,Sheen IS,Wang YC,Gu SL,Chu CM,Shih SC,Wang PC,Chang WH,Wang HY

更新日期：2004-03-01 00:00:00

abstract：:Two-dimensional shear wave elastography (2D-SWE) is a rapid, simple and novel noninvasive method that has been proposed for assessing hepatic fibrosis in patients with chronic liver diseases (CLDs) based on measurements of liver stiffness. 2D-SWE can be performed easily at the bedside or in an outpatient clinic and yi...

journal_title：World journal of gastroenterology

authors： Xie LT,Yan CH,Zhao QY,He MN,Jiang TA

更新日期：2018-03-07 00:00:00

abstract：:The combination of either boceprevir or telaprevir with ribavirin and interferon (triple therapy) has been shown to be more effective than ribavirin+interferon (dual therapy) for the treatment of genotype 1 hepatitis C. Since the benefit of these treatments takes place after years, simulation models are needed to pred...

journal_title：World journal of gastroenterology

authors： Messori A,Fadda V,Maratea D,Trippoli S

更新日期：2012-06-21 00:00:00

abstract：AIM:H101, an E1B 55 kD gene deleted adenovirus, has been shown to possess oncolysis activity experimentally and proved to be safe in preliminary phase I study. The current study was designed to evaluate its anti-tumor activity and toxicity in combination with chemotherapy in patients with late stage cancers. METHODS:H...

journal_title：World journal of gastroenterology

authors： Lu W,Zheng S,Li XF,Huang JJ,Zheng X,Li Z

更新日期：2004-12-15 00:00:00

abstract：AIM:To study the blood-brain barrier integrity, brain edema, animal behavior and ammonia plasma levels in prehepatic portal hypertensive rats with and without acute liver intoxication. METHODS:Adults male Wistar rats were divided into four groups. Group I: sham operation; II: Prehepatic portal hypertension, produced b...

journal_title：World journal of gastroenterology

authors： Scorticati C,Prestifilippo JP,Eizayaga FX,Castro JL,Romay S,Fernández MA,Lemberg A,Perazzo JC

更新日期：2004-05-01 00:00:00

abstract：AIM:To investigate whether the patatin-like phospholipase domain containing-3 gene (PNPLA3) I148M polymorphism is associated with steatosis, fibrosis stage, and cirrhosis in hereditary hemochromatosis (HH). METHODS:We studied 174 consecutive unrelated homozygous for the C282Y HFE mutation of HH (C282Y+/+ HH) patients ...

journal_title：World journal of gastroenterology

authors： Valenti L,Maggioni P,Piperno A,Rametta R,Pelucchi S,Mariani R,Dongiovanni P,Fracanzani AL,Fargion S

更新日期：2012-06-14 00:00:00

abstract：AIM:Various side effects have been reported in patients infected with hepatitis C virus (HCV) who were treated with interferon-alpha (IFN-alpha), including the appearance or exacerbation of underlying autoimmune diseases and the development of a variety of organ and non-organ specific autoantibodies (NOSA). However, ve...

journal_title：World journal of gastroenterology

authors： Gatselis NK,Georgiadou SP,Tassopoulos N,Zachou K,Liaskos C,Hatzakis A,Dalekos GN

更新日期：2005-01-28 00:00:00

abstract：AIM:To study the factors that may affect survival of cholangiocarcinoma in Lebanon. METHODS:A retrospective review of the medical records of 55 patients diagnosed with cholangio-carcinoma at the American University of Beirut between 1990 and 2005 was conducted. Univariate and multivariate analyses were performed to de...

journal_title：World journal of gastroenterology

authors： Farhat MH,Shamseddine AI,Tawil AN,Berjawi G,Sidani C,Shamseddeen W,Barada KA

更新日期：2008-05-28 00:00:00

abstract：AIM:To investigate the tumor-suppressive effect of the phosphatase and tensin homologue deleted from chromosome (PTEN) in human gastric cancer cells that were wild type for PTEN. METHODS:Adenoviruses expressing PTEN or luciferase as a control were introduced into gastric cancer cells. The effect of exogenous PTEN gene...

journal_title：World journal of gastroenterology

authors： Hang Y,Zheng YC,Cao Y,Li QS,Sui YJ

更新日期：2005-04-21 00:00:00

abstract：AIM:To determine whether aspirin or non-aspirin non-steroidal anti-inflammatory drugs (NA-NSAIDs) prevent colorectal cancer (CRC) in patients with inflammatory bowel disease (IBD). METHODS:We performed a systematic review and meta-analysis. We searched for articles reporting the risk of CRC in patients with IBD relate...

journal_title：World journal of gastroenterology

authors： Burr NE,Hull MA,Subramanian V

更新日期：2016-04-07 00:00:00

abstract：AIM:To investigate genetic factors that might help define which Crohn's disease (CD) patients are likely to benefit from anti-tumor necrosis factor (TNF) therapy. METHODS:This was a prospective cohort study. Patients were recruited from a university digestive disease practice database. We included CD patients who rece...

journal_title：World journal of gastroenterology

authors： Netz U,Carter JV,Eichenberger MR,Dryden GW,Pan J,Rai SN,Galandiuk S

更新日期：2017-07-21 00:00:00

abstract：:Celiac disease (CD) is manifested by a variety of clinical signs and symptoms that may begin either in childhood or adult life. Neurological symptoms without signs of malabsorption have been observed for a long time in CD. In this report, an 8-year-old girl with CD presented with rarely seen dilated cardiomyopathy and...

journal_title：World journal of gastroenterology

authors： Doğan M,Peker E,Cagan E,Akbayram S,Acikgoz M,Caksen H,Uner A,Cesur Y

更新日期：2010-05-14 00:00:00

abstract：AIM:To compare the therapeutic effects of proton pump inhibitors vs H₂ receptor antagonists for upper gastrointestinal bleeding in patients after successful endoscopy. METHODS:We searched the Cochrane library, MEDLINE, EMBASE and PubMed for randomized controlled trials until July 2014 for this study. The risk of bias ...

journal_title：World journal of gastroenterology

authors： Zhang YS,Li Q,He BS,Liu R,Li ZJ

更新日期：2015-05-28 00:00:00

abstract：:Deficiencies in vitamins or other factors (B6, B12, folic acid, betaine) and genetic disorders for the metabolism of the non-protein amino acid-homocysteine (Hcy) lead to hyperhomocysteinemia (HHcy). HHcy is an integral component of several disorders including cardiovascular disease, neurodegeneration, diabetes and al...

journal_title：World journal of gastroenterology

authors： Ji C,Kaplowitz N

更新日期：2004-06-15 00:00:00

abstract：AIM:To investigate the role of SCCA2 and other SCCA1 molecules in the process of hepatitis B virus (HBV) binding to mammalian cells. METHODS:SCCA1 and SCCA2 were isolated from HepG2. Binding protein (BP) genes were obtained through PCR. Recombinant baculoviruses expressing SCCA1, SCCA2, BP, and different mutants were ...

journal_title：World journal of gastroenterology

authors： Chen M,Cheng T,Xu CY,Wu T,Ou SH,Zhang T,Zhang J,Xia NS

更新日期：2005-05-21 00:00:00

abstract：:While therapeutic strategies able to change the natural history of the disease are developing, it is of major importance to have available predictive factors for aggressive disease to try and target these therapeutic strategies. Clinical predictors have probably been the most broadly studied. In both Crohn's disease (...

journal_title：World journal of gastroenterology

authors： Louis E,Belaiche J,Reenaers C

更新日期：2010-06-07 00:00:00