Therapeutic proteasome inhibition in experimental acute pancreatitis.

abstract：AIM:To demonstrate that caudate lobectomy is a valid treatment in cases of hepatocellular carcinoma (HCC) rupture in the caudate lobe based on our experience with the largest case series reported to date. METHODS:A retrospective study of eight patients presenting with spontaneous rupture and hemorrhage of HCC in the c...

journal_title：World journal of gastroenterology

authors： Hong DF,Liu YB,Peng SY,Pang JZ,Wang ZF,Cheng J,Shen GL,Zhang YB

更新日期：2015-07-14 00:00:00

abstract：AIM:To study the influence of redox environment of Escherichia coli (E. coli) cytoplasm on disulfide bond formation of recombinant proteins. METHODS:Bovine fibroblast growth factor (BbFGF) was selected as a model of simple proteins with a single disulfide bond and free cysteines. Anti-HBsAg single-chain Fv (HBscFv), a...

journal_title：World journal of gastroenterology

authors： Xiong S,Wang YF,Ren XR,Li B,Zhang MY,Luo Y,Zhang L,Xie QL,Su KY

更新日期：2005-02-21 00:00:00

abstract：AIM:To evaluate the effect of long-term treatment with leukocyte natural α-interferon (ln-α-IFN) plus ribavirin (RBV). METHODS:Forty-six patients with hepatitis C virus (HCV) recurrence received 3 MU three times a week of ln-α-IFN plus RBV for 1 mo; then, patients with good tolerability (n = 30) were switched to daily...

journal_title：World journal of gastroenterology

authors： Tamè M,Buonfiglioli F,Del Gaudio M,Lisotti A,Cecinato P,Colecchia A,Azzaroli F,D'Errico A,Arena R,Calvanese C,Quarneti C,Ballardini G,Pinna AD,Mazzella G

更新日期：2013-08-28 00:00:00

abstract：:Gastrointestinal duplication is an uncommon congenital abnormality in two-thirds of cases manifesting before the age of 2 years. Ileal duplication is common while colonic duplication, either cystic or tubular, is a rather unusual clinical entity that remains asymptomatic and undiagnosed in most cases. Mostly occurring...

journal_title：World journal of gastroenterology

authors： Fotiadis C,Genetzakis M,Papandreou I,Misiakos EP,Agapitos E,Zografos GC

更新日期：2005-08-28 00:00:00

abstract：AIM:To examine fibrinogen-like protein 2 (fgl2) expression during taurocholate-induced acute pancreatitis progression in rats and its correlation with pancreatic injury severity. METHODS:Forty-eight male Sprague-Dawley rats were randomly divided into the severe acute pancreatitis (SAP) group (n = 24) and the sham oper...

journal_title：World journal of gastroenterology

authors： Ye XH,Chen TZ,Huai JP,Lu GR,Zhuge XJ,Chen RP,Chen WJ,Wang C,Huang ZM

更新日期：2013-04-28 00:00:00

abstract：AIM:To determine the prevalence, histologic types and clinical features of primary epithelial tumours of the vermiform appendix in a predominantly black population. METHODS:All cases of primary tumours of the appendix identified by review of the histopathology records at the University of the West Indies between Janua...

journal_title：World journal of gastroenterology

authors： Graham RP,Williams NP,West KA

更新日期：2009-03-28 00:00:00

abstract：AIM:To investigate whether illness severity has an impact on gastric residual volume (GRV) in medical critically ill patients. METHODS:Medical intensive care unit (ICU) patients requiring nasogastric feeding were enrolled. Sequential Organ Failure Assessment (SOFA) score was assessed immediately preceding the start of...

journal_title：World journal of gastroenterology

authors： Hsu CW,Sun SF,Lee DL,Lin SL,Wong KF,Huang HH,Li HJ

更新日期：2011-04-21 00:00:00

abstract：:Barrett's esophagus (BE) is characterized by intestinal metaplasia with the differentiated epithelium replaced by another type of epithelium morphologically similar to normal intestinal epithelium. The metaplasia is preceded by bile and acid reflux into the esophagus. BE is a premalignant condition associated with inc...

journal_title：World journal of gastroenterology

authors： Zhao J,Gregersen H

更新日期：2013-05-14 00:00:00

abstract：AIM:To elucidate the relationship between the microvessel count (MVC) by CD34 analyzed by immunohistochemical method and prognosis in hepatocellular carcinoma (HCC) patients who underwent hepatectomy based on our preliminary study. METHODS:We examined relationships between MVC and clinicopathological factors in 128 HC...

journal_title：World journal of gastroenterology

authors： Nanashima A,Nakayama T,Sumida Y,Abo T,Takeshita H,Shibata K,Hidaka S,Sawai T,Yasutake T,Nagayasu T

更新日期：2008-08-21 00:00:00

abstract：AIM:To study the outcome of patients undergoing surgical resection of the bowel for sustained radiation-induced damage intractable to conservative management. METHODS:During a 7-year period we operated on 17 cases (5 male, 12 female) admitted to our surgical department with intestinal radiation injury (IRI). They were...

journal_title：World journal of gastroenterology

authors： Perrakis N,Athanassiou E,Vamvakopoulou D,Kyriazi M,Kappos H,Vamvakopoulos NC,Nomikos I

更新日期：2011-09-21 00:00:00

abstract：AIM:To assess the importance of preoperative diagnosis and presentation of left-sided gallbladder using ultrasound (US), CT and angiography. METHODS:Retrospective review of 1482 patients who underwent enhanced CT scanning was performed. Left-sided gallbladder was diagnosed if a right-sided ligamentum teres was present...

journal_title：World journal of gastroenterology

authors： Hsu SL,Chen TY,Huang TL,Sun CK,Concejero AM,Tsang LL,Cheng YF

更新日期：2007-12-21 00:00:00

abstract：:Enzymatic metabolism of the 20C polyunsaturated fatty acid (PUFA) arachidonic acid (AA) occurs via the cyclooxygenase (COX) and lipoxygenase (LOX) pathways, and leads to the production of various bioactive lipids termed eicosanoids. These eicosanoids have a variety of functions, including stimulation of homeostatic re...

journal_title：World journal of gastroenterology

authors： Tuncer S,Banerjee S

更新日期：2015-11-07 00:00:00

abstract：:AIM:To explore the expression and changes of hepatoma specific alkaline phospatase (ALP) in rats during canceration.METHODS:The ALPs and isoenzymes of rat livers and sera were investigated in SD hepatomas induced with 0.05% 2-fluoenylacetamide (2-FAA).RESULTS: By pathological examination and biochemical analysis. ALPs...

journal_title：World journal of gastroenterology

authors： Xiao MB,Yao DF,Zhang H,Qiang H,Huang JF,Wei Q,Jiang F

更新日期：1998-08-01 00:00:00

abstract：AIM:To analyze the Hepatitis C virus (HCV) genotype distribution and transmission risk factors in a population of unselected patients in Luxembourg. METHODS:Epidemiological information (gender, age and transmission risks) were collected from 802 patients newly diagnosed for hepatitis C and living in Luxembourg, among ...

journal_title：World journal of gastroenterology

authors： Roman F,Hawotte K,Struck D,Ternes AM,Servais JY,Arendt V,Hoffman P,Hemmer R,Staub T,Seguin-Devaux C,Schmit JC

更新日期：2008-02-28 00:00:00

abstract：AIM:To find out whether a newly designed big cup nitinol stent is suitable for treatment of patients with gastric outlet obstruction resulting from gastric cancer. METHODS:The new stent is composed of a proximal big cup segment (20 mm in length and 48-55 mm in diameter), a middle part (60 mm in length and 20 mm in dia...

journal_title：World journal of gastroenterology

authors： Shi D,Liao SH,Geng JP

更新日期：2010-09-07 00:00:00

abstract：:Repeated surveys from Europe, the United States, Australia, and New Zealand have shown that adherence to an evidence-based perioperative care protocol, such as Enhanced Recovery After Surgery (ERAS), has been generally low. It is of great importance to support the implementation of the ERAS protocol as it has been sho...

journal_title：World journal of gastroenterology

authors： Segelman J,Nygren J

更新日期：2014-11-28 00:00:00

abstract：AIM:To assess the role of IgM and IgG immunohistochemistry (IHC) in the evaluation of autoimmune liver conditions--autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC). METHODS:Forty one biopsies from untreated patients diagnosed with autoimmune liver disease (AIH, n = ...

journal_title：World journal of gastroenterology

authors： Moreira RK,Revetta F,Koehler E,Washington MK

更新日期：2010-01-28 00:00:00

abstract：AIM:To investigate the effects of KAI1/CD82 on biological behavior of colorectal carcinoma cells. METHODS:KAI1 cDNA was transfected into highly malignant colorectal carcinoma cell line, LoVo, which had low level of endogenous KAI1 expression, and established stable transfectant clones with high KAI1/CD82 expression. T...

journal_title：World journal of gastroenterology

authors： Liu L,Wu DH,Li ZG,Yang GZ,Ding YQ

更新日期：2003-06-01 00:00:00

abstract：AIM:To clarify the strategy for early diagnosis of pancreaticobiliary maljunction (PBM) without biliary dilatation and to pathologically examine gallbladder before cancer develops. METHODS:The anatomy of the union of the pancreatic and bile ducts was assessed by using endoscopic retrograde cholangiopancreatography (ER...

journal_title：World journal of gastroenterology

authors： Takuma K,Kamisawa T,Tabata T,Hara S,Kuruma S,Inaba Y,Kurata M,Honda G,Tsuruta K,Horiguchi S,Igarashi Y

更新日期：2012-07-14 00:00:00

abstract：:Bone metastases from gastric cancer (GC) are considered a relatively uncommon finding; however, they are related to poorer prognosis. Both primary GC and its metastatic progression rely on angiogenesis. Several lines of evidence from GC patients strongly support the involvement of mast cells (MCs) positive to tryptase...

journal_title：World journal of gastroenterology

authors： Leporini C,Ammendola M,Marech I,Sammarco G,Sacco R,Gadaleta CD,Oakley C,Russo E,De Sarro G,Ranieri G

更新日期：2015-10-07 00:00:00

abstract：:Duodenal polyps or lesions are uncommonly found on upper endoscopy. Duodenal lesions can be categorized as subepithelial or mucosally-based, and the type of lesion often dictates the work-up and possible therapeutic options. Subepithelial lesions that can arise in the duodenum include lipomas, gastrointestinal stromal...

journal_title：World journal of gastroenterology

authors： Gaspar JP,Stelow EB,Wang AY

更新日期：2016-01-14 00:00:00

abstract：:AIM:To study the clinical significance of the diagnosis and catheterized interventional treatment of digital subtraction angiography (DSA) for pancreatic tumors.METHODS: Ninety-two patients with pancreatic tumor, 69 males and 23 females, aged from 41 to 70 years (mean 57.1 years) were diagnosed with DSA. Sixty-one pat...

journal_title：World journal of gastroenterology

authors： Xu HB,Zhang YJ,Wei WJ,Li WM,Tu XQ

更新日期：1998-02-01 00:00:00

abstract：AIM:To determine the frequencies of HGV and TTV infections in serum and saliva samples of non-hepatitis patients with oral diseases in Hangzhou area, and to understand the correlation between detected results of HGV RNA and/or TTV DNA in sera and in saliva from the same patients. METHODS:RT-nested PCR for HGV RNA dete...

journal_title：World journal of gastroenterology

authors： Yan J,Chen LL,Lou YL,Zhong XZ

更新日期：2002-10-01 00:00:00

abstract：AIM:To characterize the expression and dynamic changes of bone morphogenetic protein (BMP)-2 in hepatocytes in the regenerating liver in rats after partial hepatectomy (PH), and examine the effects of BMP-2 on proliferation of human Huh7 hepatoma cells. METHODS:Fifty-four adult male Wistar rats were randomly divided i...

journal_title：World journal of gastroenterology

authors： Xu CP,Ji WM,van den Brink GR,Peppelenbosch MP

更新日期：2006-12-21 00:00:00

abstract：:Direct acting antivirals (DAAs) have revolutionized the treatment of hepatitis C virus (HCV) infection, achieving high rates (≥ 95%) of sustained virological response, with a good safety profile and high compliance rates. Consequently, it had been expected that viral clearance will reduce morbidity and mortality rates...

journal_title：World journal of gastroenterology

authors： Muzica CM,Stanciu C,Huiban L,Singeap AM,Sfarti C,Zenovia S,Cojocariu C,Trifan A

更新日期：2020-11-21 00:00:00

abstract：:The KRAS oncogene is mutated in approximately 35%-45% of colorectal cancers, and KRAS mutational status testing has been highlighted in recent years. The most frequent mutations in this gene, point substitutions in codons 12 and 13, were validated as negative predictors of response to anti-epidermal growth factor rece...

journal_title：World journal of gastroenterology

authors： Tan C,Du X

更新日期：2012-10-07 00:00:00

abstract：AIM:To cure typically life-threatening esophagogastric anastomosis in rats, lacking anastomosis healing and sphincter function rescue, in particular. METHODS:Because we assume esophagogastric fistulas represent a particular NO-system disability, we attempt to identify the benefits of anti-ulcer stable gastric pentadec...

journal_title：World journal of gastroenterology

authors： Djakovic Z,Djakovic I,Cesarec V,Madzarac G,Becejac T,Zukanovic G,Drmic D,Batelja L,Zenko Sever A,Kolenc D,Pajtak A,Knez N,Japjec M,Luetic K,Stancic-Rokotov D,Seiwerth S,Sikiric P

更新日期：2016-11-07 00:00:00

abstract：AIM:To investigate the effects of small interference RNA (siRNA) targeting of Cdx2 on human gastric cancer MGC-803 cells in vitro and in vivo. METHODS:The recombinant pSilencer 4.1-Cdx2 siRNA plasmids were constructed and transfected into gastric cancer MGC-803 cells in vitro. The stable transfectants were selected. T...

journal_title：World journal of gastroenterology

authors： Wang XT,Xie YB,Xiao Q

更新日期：2012-04-28 00:00:00

abstract：AIM:To investigate the systemic hemodynamic effects of two surgical procedures largely employed for treatment of schistosomal portal hypertension. METHODS:Thirty-six patients undergoing elective surgical treatment of portal hypertension due to hepatosplenic mansonic schistosomiasis were prospectively evaluated. All pa...

journal_title：World journal of gastroenterology

authors： de Cleva R,Herman P,D'albuquerque LA,Pugliese V,Santarem OL,Saad WA

更新日期：2007-11-07 00:00:00

abstract：AIM:To evaluate the effect of preoperative transcatheter arterial chemoembolization (TACE) on proliferation of hepatocellular carcinoma (HCC) cells. METHODS:A total of 136 patients with HCC underwent liver resection. Of 136 patients, 79 patients received 1 to 5 courses of TACE prior to liver resection (TACE group), wh...

journal_title：World journal of gastroenterology

authors： Xiao EH,Li JQ,Huang JF

更新日期：2007-09-07 00:00:00