Prognostic factors in patients with advanced cholangiocarcinoma: role of surgery, chemotherapy and body mass index.

abstract：AIM:To investigate changes in vasoactive intestinal polypeptide (VIP) and corticotrophin releasing factor (CRF) in the plasma and duodenum of chronic stress-induced depressed rats and the effects of fluoxetine hydrochloride (fluoxetine) treatment on depression-induced changes in VIP and CRF. METHODS:A Sprague-Dawley r...

journal_title：World journal of gastroenterology

authors： Huang YL,Yu JP,Wang GH,Chen ZH,Wang Q,Xiao L

更新日期：2007-12-07 00:00:00

abstract：:As among persons with normal anatomy, occasional patients with situs inversus develop malignant tumors. Recently, several laparoscopic operations have been reported in patients with situs inversus. We describe laparoscopic hemicolectomy with radical lymphadenectomy in such a patient. Careful consideration of the mirro...

journal_title：World journal of gastroenterology

authors： Fujiwara Y,Fukunaga Y,Higashino M,Tanimura S,Takemura M,Tanaka Y,Osugi H

更新日期：2007-10-07 00:00:00

abstract：AIM:To study the response to infliximab in pediatric inflammatory bowel disease (IBD), as reflected in fecal calprotectin levels. METHODS:Thirty-six pediatric patients with IBD [23 Crohn's disease (CD), 13 ulcerative colitis (UC); median age 14 years] were treated with infliximab. Fecal calprotectin was measured at ba...

journal_title：World journal of gastroenterology

authors： Hämäläinen A,Sipponen T,Kolho KL

更新日期：2011-12-21 00:00:00

abstract：AIM:To characterise the viral kinetics of enterovirus 71 (EV71). METHODS:In this study, human rhabdomyosarcoma (RD) cells were infected with EV71 at different multiplicity of infection (MOI). After infection, the cytopathic effect (CPE) was monitored and recorded using a phase contrast microscope associated with a CCD...

journal_title：World journal of gastroenterology

authors： Lu J,He YQ,Yi LN,Zan H,Kung HF,He ML

更新日期：2011-09-28 00:00:00

abstract：:Non celiac gluten sensitivity (NCGS) is a syndrome characterized by a cohort of symptoms related to the ingestion of gluten-containing food in subjects who are not affected by celiac disease (CD) or wheat allergy. The possibility of systemic manifestations in this condition has been suggested by some reports. In most ...

journal_title：World journal of gastroenterology

authors： Losurdo G,Principi M,Iannone A,Amoruso A,Ierardi E,Di Leo A,Barone M

更新日期：2018-04-14 00:00:00

abstract：AIM:To investigate the gastrin secreting cells (G cells) and the somatostatin secreting cells (D cells) of antral mucosa in rats at the ultrastructural level. METHODS:Revised immunoelectron microscopic technique was used to detect the G cells and D cells in rat antral mucosa through gastrin and somatostatin antibodies...

journal_title：World journal of gastroenterology

authors： Sun FP,Song YG

更新日期：2003-12-01 00:00:00

abstract：AIM:To evaluate the pharmaceutical safety of a Chinese herbal formula, chunggan extract (CGX), traditionally prescribed as a hepatotherapeutic drug via systemic acute and subacute toxicological study. METHODS:Twenty male dogs and 20 female dogs were fed doses 50 times and 4 times greater than the clinically-recommende...

journal_title：World journal of gastroenterology

authors： Choi WJ,Shin JW,Son JY,Seo DS,Park HS,Han SH,Sung HJ,Cho JH,Cho CK,Yoo HS,Lee YW,Son CG

更新日期：2006-12-14 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) in children is becoming a major health concern. A "multiple-hit" pathogenetic model has been suggested to explain the progressive liver damage that occurs among children with NAFLD. In addition to the accumulation of fat in the liver, insulin resistance (IR) and oxidative stre...

journal_title：World journal of gastroenterology

authors： Clemente MG,Mandato C,Poeta M,Vajro P

更新日期：2016-09-28 00:00:00

abstract：:Neonatal pneumoperitoneum is a surgical emergency indicative of gastrointestinal perforation that requires immediate treatment to prevent death. There have been non-surgical conditions secondary to neonatal pneumoperitoneum (e.g., mechanical ventilation, pulmonary diseases and pneumatosis cystoides intestinalis) that ...

journal_title：World journal of gastroenterology

authors： He TZ,Xu C,Ji Y,Sun XY,Liu M

更新日期：2015-05-28 00:00:00

abstract：:Tumors of the minor papilla of the duodenum are quite rare. We successfully and safely treated an 18-mm adenoma of the minor papilla associated with pancreas divisum using endoscopic papillectomy. A 64-year-old man was admitted to our hospital for treatment of an asymptomatic mass in the minor papilla detected by uppe...

journal_title：World journal of gastroenterology

authors： Kanamori A,Kumada T,Kiriyama S,Sone Y,Tanikawa M,Hisanaga Y,Toyoda H,Kawashima H,Itoh A,Hirooka Y,Goto H

更新日期：2009-03-07 00:00:00

abstract：AIM:To investigate the possible mechanism by which hepatitis B virus X protein (HBx) mediates apoptosis of HepG2 cells. METHODS:HBx expression vector pcDNA3.1-X was transfected into HepG2 cells to establish an HBx high-expression cellular model as pcDNA3.1-X transfected group. The pcDNA3.1-X and pSilencer3.1-shHBX (HB...

journal_title：World journal of gastroenterology

authors： Tang RX,Kong FY,Fan BF,Liu XM,You HJ,Zhang P,Zheng KY

更新日期：2012-04-07 00:00:00

abstract：:Multiple pathogenic mechanisms have been implicated in autoimmune hepatitis, but they have not fully explained susceptibility, triggering events, and maintenance or escalation of the disease. Furthermore, they have not identified a critical defect that can be targeted. The goals of this review are to examine the diver...

journal_title：World journal of gastroenterology

authors： Czaja AJ

更新日期：2019-12-07 00:00:00

abstract：AIM:To examine the effects of aspirin and enoxaparin on liver function, coagulation index and histopathology in a rat model of liver fibrosis. METHODS Forty-five male Sprague-Dawley rats were randomly divided into the control group (n = 5) and model group (n = 40). Thioacetamide (TAA) was used to induce liver fibrosis ...

journal_title：World journal of gastroenterology

authors： Li CJ,Yang ZH,Shi XL,Liu DL

更新日期：2017-09-21 00:00:00

abstract：AIM:To investigate markers for high-grade dysplasia for the optimal timing of liver transplantation in patients with primary sclerosing cholangitis (PSC). METHODS:Earlier data support a dysplasia-carcinoma sequence, even low- to high-grade dysplasia, in PSC-associated cholangiocarcinoma (CCA). Surveillance using endos...

journal_title：World journal of gastroenterology

authors： Boyd S,Vannas M,Jokelainen K,Isoniemi H,Mäkisalo H,Färkkilä MA,Arola J

更新日期：2017-09-07 00:00:00

abstract：:Treatment of chronic pancreatitis has been exclusively surgical for a long time. Recently, endoscopic therapy has become widely used as a primary therapeutic option. Initially performed for drainage of pancreatic cysts and pseudocysts, endoscopic treatments were adapted to biliary and pancreatic ducts stenosis. Pancre...

journal_title：World journal of gastroenterology

authors： Heyries L,Sahel J

更新日期：2007-12-14 00:00:00

abstract：:Chronic radiation proctopathy occurs in 5%-20% of patients following pelvic radiotherapy. Although many cases resolve spontaneously, some lead to chronic symptoms including diarrhea, tenesmus, urgency and persistent rectal bleeding with iron deficiency anemia requiring blood transfusions. Treatments for chronic radiat...

journal_title：World journal of gastroenterology

authors： Rustagi T,Mashimo H

更新日期：2011-11-07 00:00:00

abstract：AIM:To study the expression of ether à go-go (Eag1) potassium channel in colorectal cancer and the relation-ship between their expression and clinico-pathological features. METHODS:The expression levels of Eag1 protein were determined in 76 cancer tissues with paired non-cancerous matched tissues as well as 9 colorect...

journal_title：World journal of gastroenterology

authors： Ding XW,Yan JJ,An P,Lü P,Luo HS

更新日期：2007-02-28 00:00:00

abstract：:Gastric cancer and liver cancer are among the most common malignancies and the leading causes of death worldwide, due to late detection and high recurrence rates. Today, these cancers have a heavy socioeconomic burden, for which a full understanding of their pathophysiological features is warranted to search for promi...

journal_title：World journal of gastroenterology

authors： Cao DX,Li ZJ,Jiang XO,Lum YL,Khin E,Lee NP,Wu GH,Luk JM

更新日期：2012-08-14 00:00:00

abstract：:We report a rare case of a 74-year-old man with metachronous gallbladder cancer and bile duct cancer who underwent curative resection twice, with the operations nine years apart. At the age of 65 years, the patient underwent a cholecystectomy and resection of the liver bed for gallbladder cancer. This was a well-diffe...

journal_title：World journal of gastroenterology

authors： Joo HJ,Kim GH,Jeon WJ,Chae HB,Park SM,Youn SJ,Choi JW,Sung R

更新日期：2009-07-21 00:00:00

abstract：AIM:Intrabiliary rupture (IBR) is a common and serious complication of hepatic hydatid cyst. The incidence varies from 1% to 25%. The treatment of IBR is still controversial. We aimed to design an algorithm for the treatment of hepatic hydatidosis with IBR by reviewing our cases. METHODS:Eight cases of IBR were analyz...

journal_title：World journal of gastroenterology

authors： Erzurumlu K,Dervisoglu A,Polat C,Senyurek G,Yetim I,Hokelek M

更新日期：2005-04-28 00:00:00

abstract：:We report a case of hepatocellular carcinoma (HCC) occurring in a patient with Crohn's disease (CD) without chronic hepatitis or liver cirrhosis, and review the clinicopathological features of HCC in CD patients. A 37-year-old Japanese man with an 8-year history of CD and a medication history of azathioprine underwent...

journal_title：World journal of gastroenterology

authors： Ishida M,Naka S,Shiomi H,Tsujikawa T,Andoh A,Nakahara T,Saito Y,Kurumi Y,Takikita-Suzuki M,Kojima F,Hotta M,Tani T,Fujiyama Y,Okabe H

更新日期：2010-07-07 00:00:00

abstract：AIM:To investigate the effect of regulatory peptides bombesin (BBS) and neurotensin (NT) on intestinal barrier function in partially hepatectomized rats. METHODS:Ninety male Wistar rats were randomly divided into five groups: I (n=0): controls, II (n= 20): sham operated, III (n=20): partial hepatectomy 70% (PHx), IV (...

journal_title：World journal of gastroenterology

authors： Assimakopoulos SF,Alexandris IH,Scopa CD,Mylonas PG,Thomopoulos KC,Georgiou CD,Nikolopoulou VN,Vagianos CE

更新日期：2005-11-21 00:00:00

abstract：AIM:To explore the influence of polymorphisms in genes encoding for the chemokines Stromal cell-Derived Factor-1 (SDF-1)/CXCL12 and Monocyte Chemotactic Protein-1 (MCP-1)/CCL2, or for the chemokine receptor CCR5 on the risks of liver-related death and hepatocellular carcinoma (HCC) occurrence in hepatitis C virus (HCV)...

journal_title：World journal of gastroenterology

authors： Nahon P,Sutton A,Rufat P,Simon C,Trinchet JC,Gattegno L,Beaugrand M,Charnaux N

更新日期：2008-02-07 00:00:00

abstract：:The number of patients with gastric cancer has more than doubled since 1985 in developing countries. Thus, the questions of whether it can be predicted from gastritis morphology, who is at risk and who has a lower risk of developing gastric carcinoma are raised. H pylori-infection leads to erosions, ulcerations, carci...

journal_title：World journal of gastroenterology

authors： Vieth M,Stolte M

更新日期：2006-10-14 00:00:00

abstract：AIM:To investigate the risk indicators, pattern of clinical presentation and treatment strategy of superior mesenteric artery syndrome (SMAS) after scoliosis surgery. METHODS:From July 1997 to October 2003, 640 patients with adolescent scoliosis who had undergone surgical treatment were evaluated prospectively, and am...

journal_title：World journal of gastroenterology

authors： Zhu ZZ,Qiu Y

更新日期：2005-06-07 00:00:00

abstract：:Gut microbiota plays a key role in the pathogenesis of alcoholic liver disease (ALD). Consumption of alcohol leads to increased gut permeability, small intestinal bacterial overgrowth, and enteric dysbiosis. These factors contribute to the increased translocation of microbial products to the liver via the portal tract...

journal_title：World journal of gastroenterology

authors： Sung H,Kim SW,Hong M,Suk KT

更新日期：2016-08-07 00:00:00

abstract：AIM:To investigate the potential therapeutic effect of exopolysaccharide (EPS)-producing Streptococcus thermophilus (S. thermophilus) CRL 1190 fermented milk on chronic gastritis in Balb/c mice. METHODS:Balb/c mice were fed with the fermented milk for 7 d after inducing gastritis with acetyl-salicylic acid (ASA, 400 m...

journal_title：World journal of gastroenterology

authors： Rodríguez C,Medici M,Mozzi F,Font de Valdez G

更新日期：2010-04-07 00:00:00

abstract：AIM:To investigate the mechanisms of anti-liver fibrosis actions of Fuzheng Huayu (FZHY) decoction, which acts to strengthen the body's resistance and promote blood circulation. METHODS:Ito cells were isolated from rats and cultured. Serum samples were collected from healthy (normal) rats after administration of FZHY ...

journal_title：World journal of gastroenterology

authors： Liu CH,Liu C,Liu P,Xu LM

更新日期：1997-12-15 00:00:00

abstract：AIM:To investigate the role of pre-core and basal core promoter (BCP) mutations before and after hepatitis B e antigen (HBeAg) seroconversion. METHODS:The proportion of pre-core (G1896A) and basal core promoter (A1762T and G1764A) mutant viruses and serum levels of hepatitis B virus (HBV) DNA, hepatitis B surface anti...

journal_title：World journal of gastroenterology

authors： Kamijo N,Matsumoto A,Umemura T,Shibata S,Ichikawa Y,Kimura T,Komatsu M,Tanaka E

更新日期：2015-01-14 00:00:00

abstract：AIM:To explore the quantitative analysis of diffusion-weighted magnetic resonance imaging (DWMRI) in differential diagnosis of focal hepatic lesions. METHODS:DWMRI was performed in 149 hepatic lesions, including hepatocellular carcinoma (34 cases), hepatic metastases (37 cases), cavernous hemangioma (42 cases), hepati...

journal_title：World journal of gastroenterology

authors： Sun XJ,Quan XY,Huang FH,Xu YK

更新日期：2005-11-07 00:00:00