Mutations of pre-core and basal core promoter before and after hepatitis B e antigen seroconversion.

abstract：:The paper provides a basic review of intestinal microflora and its importance in liver diseases. The intestinal microflora has many important functions, above all to maintain the microbial barrier against established as well as potential pathogens. Furthermore, it influences the motility and perfusion of the intestina...

journal_title：World journal of gastroenterology

authors： Lata J,Jurankova J,Kopacova M,Vitek P

更新日期：2011-06-28 00:00:00

abstract：AIM:To assess the outcome of patients, who underwent transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) and subsequently liver transplantation (OLT) irrespective of tumor size when no tumor progression was observed. METHODS:Records, imaging studies and pathology of 84 patients with HCC were revi...

journal_title：World journal of gastroenterology

authors： Obed A,Beham A,Püllmann K,Becker H,Schlitt HJ,Lorf T

更新日期：2007-02-07 00:00:00

abstract：AIM:To compare the clinical efficacy of the second-generation H2RA lafutidine with that of lansoprazole in Japanese patients with mild gastroesophageal reflux disease (GERD). METHODS:Patients with symptoms of GERD and a diagnosis of grade A reflux esophagitis (according to the Los Angeles classification) were randomiz...

journal_title：World journal of gastroenterology

authors： Takenaka R,Okada H,Kawano S,Komazawa Y,Yoshinaga F,Nagata S,Inoue M,Komatsu H,Onogawa S,Kushiyama Y,Mukai S,Todo H,Okanobu H,Manabe N,Tanaka S,Haruma K,Kinoshita Y

更新日期：2016-06-21 00:00:00

abstract：AIM:To test whether ethanol feeding could induce Toll-like receptor 4 (TLR4) responses, assess the hepatoprotective effect of betaine and its inhibitive effect on TLR4 in animal models of alcoholic liver injury. METHODS:Forty-eight female Sprague-Dawley rats were randomly divided into four groups as control, model, lo...

journal_title：World journal of gastroenterology

authors： Shi QZ,Wang LW,Zhang W,Gong ZJ

更新日期：2010-02-21 00:00:00

abstract：:Reduction of low-density lipoprotein-cholesterol through statin therapy has only modestly decreased coronary heart disease (CHD)-associated mortality in developed countries, which has prompted the search for alternative therapeutic strategies for CHD. Major efforts are now focused on therapies that augment high-densit...

journal_title：World journal of gastroenterology

authors： Temel RE,Brown JM

更新日期：2010-12-21 00:00:00

abstract：AIM:To estimate the effect of a therapeutic vaccine against pancreatic carcinoma based on dendritic cell (DC) vaccine modified with tumor lysate and Interleukin-18 gene. METHODS:The BALB/C mice model of pancreatic carcinoma was induced with DMBA. DC vaccine was constructed through pulsed with tumor lysate and transfec...

journal_title：World journal of gastroenterology

authors： Tang ZH,Qiu WH,Wu GS,Yang XP,Zou SQ,Qiu FZ

更新日期：2002-10-01 00:00:00

abstract：AIM:To compare the therapeutic effects of proton pump inhibitors vs H₂ receptor antagonists for upper gastrointestinal bleeding in patients after successful endoscopy. METHODS:We searched the Cochrane library, MEDLINE, EMBASE and PubMed for randomized controlled trials until July 2014 for this study. The risk of bias ...

journal_title：World journal of gastroenterology

authors： Zhang YS,Li Q,He BS,Liu R,Li ZJ

更新日期：2015-05-28 00:00:00

abstract：AIM:To analyze the effect of intralesional steroid injections in addition to endoscopic dilation of benign refractory esophageal strictures. METHODS:A comprehensive search was performed in three databases from inception to 10 April 2017 to identify trials, comparing the efficacy of endoscopic dilation to dilation comb...

journal_title：World journal of gastroenterology

authors： Szapáry L,Tinusz B,Farkas N,Márta K,Szakó L,Meczker Á,Hágendorn R,Bajor J,Vincze Á,Gyöngyi Z,Mikó A,Csupor D,Hegyi P,Erőss B

更新日期：2018-06-07 00:00:00

abstract：AIM:To investigate the mechanisms of chloride intracellular channel 1 (CLIC1) in the metastasis of colon cancer under hypoxia-reoxygenation (H-R) conditions. METHODS:Fluorescent probes were used to detect reactive oxygen species (ROS) in LOVO cells. Wound healing assay and transwell assay were performed to examine the...

journal_title：World journal of gastroenterology

authors： Wang P,Zeng Y,Liu T,Zhang C,Yu PW,Hao YX,Luo HX,Liu G

更新日期：2014-02-28 00:00:00

abstract：AIM:To investigate the prognostic value of vascular endothelial growth factor messenger RNA (VEGF mRNA) in the peripheral blood (PB) of patients with hepatocellular carcinoma (HCC) undergoing curative resection. METHODS:Using a reverse-transcription polymerase chain reaction (RT-PCR)-based assay, VEGF mRNA in the PB w...

journal_title：World journal of gastroenterology

authors： Jeng KS,Sheen IS,Wang YC,Gu SL,Chu CM,Shih SC,Wang PC,Chang WH,Wang HY

更新日期：2004-03-01 00:00:00

abstract：:In this paper, we summarize the main progresses made in our group in the field of the mechanism of pigment gallstone formation. It was found that after treatment with free radicals, bilirubin (BR) was changed into free radical itself, and a semiquinone free radical and a superoxide free radical bound with metal were r...

journal_title：World journal of gastroenterology

authors： Liu XT,Hu J

更新日期：2002-06-01 00:00:00

abstract：:Mesenteric venous thrombosis (MVT) is a rare but life threatening form of bowel ischemia. It is implicated in 6%-9% of all cases of acute mesenteric ischemia. The proportion of patients with primary (or idiopathic) MVT varies from 0% to 49%, with a decrease in frequency secondary to more recent availability of newer i...

journal_title：World journal of gastroenterology

authors： Karmacharya P,Aryal MR,Donato A

更新日期：2013-11-21 00:00:00

abstract：AIM:To study the expression of trefoil factor 1 (TFF1) and TFF2 in precancerous condition and gastric cancer and to explore the relationship between TFFs and tumorigenesis, precancerous condition and gastric cancer. METHODS:The expression of TFF1 and TFF2 was immunohistochemically analyzed in paraffin-embedded samples...

journal_title：World journal of gastroenterology

authors： Shi SQ,Cai JT,Yang JM

更新日期：2006-05-21 00:00:00

abstract：AIM:To determine whether a specific adenosine A(2A) receptor agonist (ATL-146e) can ameliorate aspirin-induced gastric mucosal lesions in rats, and reduce neutrophil accumulation and production of pro-inflammatory cytokines. METHODS:Gastric lesions were produced by oral gavage of aspirin (200 mg/kg) and HCl (0.15 mol/...

journal_title：World journal of gastroenterology

authors： Odashima M,Otaka M,Jin M,Komatsu K,Wada I,Horikawa Y,Matsuhashi T,Hatakeyama N,Oyake J,Ohba R,Watanabe S,Linden J

更新日期：2006-01-28 00:00:00

abstract：AIM:To evaluate the predictive value of tissue transglutaminase (tTG) antibodies for villous atrophy in adult and pediatric populations to determine if duodenal biopsy can be avoided. METHODS:A total of 324 patients with celiac disease (CD; 97 children and 227 adults) were recruited prospectively at two tertiary cente...

journal_title：World journal of gastroenterology

authors： Vivas S,Ruiz de Morales JG,Riestra S,Arias L,Fuentes D,Alvarez N,Calleja S,Hernando M,Herrero B,Casqueiro J,Rodrigo L

更新日期：2009-10-14 00:00:00

abstract：AIM:To investigate the safety and feasibility of needlescopic grasper-assisted single-incision laparoscopic common bile duct exploration (nSIL-CBDE) by comparing the surgical outcomes of this technique with those of conventional laparoscopic CBDE (CL-CBDE). METHODS:We retrospectively analyzed the clinical data of pati...

journal_title：World journal of gastroenterology

authors： Kim SJ,Kim KH,An CH,Kim JS

更新日期：2015-12-07 00:00:00

abstract：:Intestinal capillariasis caused by Capillaria philippinensis appeared first in the Philippines and subsequently in Thailand, Japan, Iran, Egypt and Taiwan; major outbreaks have occurred in the Philippines and Thailand. This article reviews the epidemiology, history and sources of C. philippinensis infection in Thailan...

journal_title：World journal of gastroenterology

authors： Saichua P,Nithikathkul C,Kaewpitoon N

更新日期：2008-01-28 00:00:00

abstract：AIM:To discuss the expression of human leukocyte antigen (HLA) class I antigens in gastric cancer and correlate these with pathologic type and TNM stage. METHODS:The expression of HLA class I antigen was detected by immunohistochemistry in 185 specimens of gastric cancer, 20 gastric cancer specimens with lymphatic met...

journal_title：World journal of gastroenterology

authors： Shen YQ,Zhang JQ,Miao FQ,Zhang JM,Jiang Q,Chen H,Shan XN,Xie W

更新日期：2005-06-21 00:00:00

abstract：AIM:To investigate the microRNA expression profile in esophageal neosquamous epithelium from patients who had undergone ablation of Barrett's esophagus. METHODS:High throughput screening using TaqMan® Array Human MicroRNA quantitative PCR was used to determine expression levels of 754 microRNAs in distal esophageal mu...

journal_title：World journal of gastroenterology

authors： Sreedharan L,Mayne GC,Watson DI,Bright T,Lord RV,Ansar A,Wang T,Kist J,Astill DS,Hussey DJ

更新日期：2017-08-14 00:00:00

abstract：:Confocal laser endomicroscopy (CLE) is a newly introduced procedure that provide real-time, high-resolution imaging of the gastrointestinal mucosa during endoscopy, allowing the visualization of the pathology of the mucosal epithelium with its cellular and subcellular structures. Recently, the use of CLE was reported ...

journal_title：World journal of gastroenterology

authors： De Palma GD,Rispo A

更新日期：2013-09-14 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) represents the sixteenth most frequent cancer in Argentina. The rise of new therapeutic modalities in intermediate-advanced HCC opens up a new paradigm for the treatment of HCC. AIM:To describe real-life treatments performed in patients with intermediate-advanced HCC before th...

journal_title：World journal of gastroenterology

authors： Piñero F,Marciano S,Fernández N,Silva J,Anders M,Zerega A,Ridruejo E,Romero G,Ameigeiras B,D'Amico C,Gaite L,Bermúdez C,Reggiardo V,Colombato L,Gadano A,Silva M

更新日期：2019-07-21 00:00:00

abstract：AIM:To identify new diagnostic markers and drug targets, the gene expression profiles of pancreatic cancer were compared with that of adjacent normal tissues utilizing cDNA microarray analysis. METHODS:cDNA probes were prepared by labeling mRNA from samples of six pancreatic carcinoma tissues with Cy5-dUTP and mRNA fr...

journal_title：World journal of gastroenterology

authors： Tan ZJ,Hu XG,Cao GS,Tang Y

更新日期：2003-04-01 00:00:00

abstract：AIM:To review the cases reported in the literature, examined their clinicopathological features, and evaluated the efficacy of different therapeutic modalities for this rare condition. METHODS:A search of the MEDLINE database revealed 16 cases of pericarditis carcinomatosa (PC) originating from GC reported in the lite...

journal_title：World journal of gastroenterology

authors： Kobayashi M,Okabayashi T,Okamoto K,Namikawa T,Araki K

更新日期：2005-11-28 00:00:00

abstract：AIM:To characterize AXL receptor tyrosine kinase (AXL) expression in relationship to tumor protein P53 (TP53 gene, p53 protein) and its role in tumor invasion and response to therapy. METHODS:We used 14 cell lines, including 3 isogenic pairs carrying mutant/knockout p53, to gain insight into the relationship between A...

journal_title：World journal of gastroenterology

authors： Abdel-Rahman WM,Al-Khayyal NA,Nair VA,Aravind SR,Saber-Ayad M

更新日期：2017-05-21 00:00:00

abstract：:Chronic intestinal pseudo-obstruction (CIPO) is a rare disease due to a severe gastrointestinal motility disorder which may mimic, on both clinical and radiological grounds, mechanical obstruction. We report a case of a 26-year-old woman who presented to our institution for plain abdominal radiography for referred lon...

journal_title：World journal of gastroenterology

authors： Camera L,Calabrese M,Sarnelli G,Longobardi M,Rocco A,Cuomo R,Salvatore M

更新日期：2011-06-28 00:00:00

abstract：AIM:To elucidate the role and alterations of syndecan-1 and E-cadherin expression in different cellular phenotypes of differentiated-type gastric cancers (DGCs). METHODS:A total of 120 DGCs at an early stage, and their adjacent mucosa, were studied both by immunohistochemistry. Syndecan-1 and E-cadherin were assessed ...

journal_title：World journal of gastroenterology

authors： Huang MF,Zhu YQ,Chen ZF,Xiao J,Huang X,Xiong YY,Yang GF

更新日期：2005-05-21 00:00:00

abstract：AIM:The prognosis of early gastric carcinoma (EGC) is generally excellent after surgery. The presence or absence of lymph node metastasis in EGC is an important prognostic factor. The survival and recurrence rates of node-negative EGC are much better than those of node-positive EGC. This study examined the factors rela...

journal_title：World journal of gastroenterology

authors： Kim DY,Joo JK,Ryu SY,Kim YJ,Kim SK

更新日期：2004-03-01 00:00:00

abstract：:The management of intraductal papillary mucinous neoplasms (IPMN) is presently evolving as a result of the improved understanding of the natural history and biological behavior of the different pancreatic cystic neoplasms; and better preoperative diagnosis of these neoplasms due to advancement in preoperative diagnost...

journal_title：World journal of gastroenterology

authors： Goh BK

更新日期：2015-09-14 00:00:00

abstract：AIM:To analyze small intestinal bacterial overgrowth in school-aged children and the relationship between hydrogen and methane production in breath tests. METHODS:This transversal study included 85 children residing in a slum and 43 children from a private school, all aged between 6 and 10 years, in Osasco, Brazil. Fo...

journal_title：World journal of gastroenterology

authors： Mello CS,Tahan S,Melli LC,Rodrigues MS,de Mello RM,Scaletsky IC,de Morais MB

更新日期：2012-11-07 00:00:00

abstract：AIM:To investigate the expression and activity of leukotriene C4 (LTC4) synthesis enzymes and their underlying relationship with cysteinyl leukotriene (cys-LT) generation in a rat fulminant hepatic failure (FHF) model induced by D-galactosamine/lipopolysaccharide (D-GalN/ LPS). METHODS:Rats were treated with D-GalN (3...

journal_title：World journal of gastroenterology

authors： Ma KF,Yang HY,Chen Z,Qi LY,Zhu DY,Lou YJ

更新日期：2008-05-07 00:00:00