Abstract:
:Mesenteric venous thrombosis (MVT) is a rare but life threatening form of bowel ischemia. It is implicated in 6%-9% of all cases of acute mesenteric ischemia. The proportion of patients with primary (or idiopathic) MVT varies from 0% to 49%, with a decrease in frequency secondary to more recent availability of newer investigations for hypercoagulability. The presence of factor V Leiden (FVL) and prothrombin G20210A mutations (PGM) have been well documented in these cases. However, there have been scarce case reports describing MVT in heterozygotes of both these mutations occurring simultaneously and its implications on long term management. Our case describes acute MVT in a previously asymptomatic young patient with no prior history of venous thromboembolism. The patient was found to be heterozygous for FVL and PGM and treated with lifelong anticoagulation with warfarin (goal international normalized ratio: 2-3) and avoidance of hormonal contraceptives.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Karmacharya P,Aryal MR,Donato Adoi
10.3748/wjg.v19.i43.7813subject
Has Abstractpub_date
2013-11-21 00:00:00pages
7813-5issue
43eissn
1007-9327issn
2219-2840journal_volume
19pub_type
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