Abstract:
AIM:To determine the prevalence of gastrointestinal neoplasia among dermatomyositis patients who underwent an esophagogastroduodenoscopy and/or colonoscopy. METHODS:A cross-sectional study examining the results of upper endoscopy and colonoscopy in adults with dermatomyositis at an urban, university hospital over a ten year period was performed. Chart review was performed to confirm the diagnosis of dermatomyositis. Findings on endoscopy were collected and statistical analyses stratified by age and presence of symptoms were performed. RESULTS:Among 373 adult patients identified through a code based search strategy, only 163 patients had dermatomyositis confirmed by chart review. Of the 47 patients who underwent upper endoscopy, two cases of Barrett's esophagus without dysplasia were identified and there were no cases of malignancy. Of the 67 patients who underwent colonoscopy, no cases of malignancy were identified and an adenoma was identified in 15% of cases. No significant differences were identified in the yield of endoscopy when stratified by age or presence of symptoms. CONCLUSION:The yield of endoscopy is low in patients with dermatomyositis and is likely similar to the general population; we identified no cases of malignancy. A code based search strategy is inaccurate for the diagnosis of dermatomyositis, calling into question the results of prior population-based studies. Larger studies with rigorously validated search strategies are necessary to understand the risk of gastrointestinal malignancy in patients with dermatomyositis.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Kidambi TD,Schmajuk G,Gross AJ,Ostroff JW,Terdiman JP,Lee JKdoi
10.3748/wjg.v23.i26.4788subject
Has Abstractpub_date
2017-07-14 00:00:00pages
4788-4795issue
26eissn
1007-9327issn
2219-2840journal_volume
23pub_type
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journal_title:World journal of gastroenterology
pub_type: 临床试验,杂志文章
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更新日期:2007-04-07 00:00:00
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