Endoscopy is of low yield in the identification of gastrointestinal neoplasia in patients with dermatomyositis: A cross-sectional study.

Abstract:

AIM:To determine the prevalence of gastrointestinal neoplasia among dermatomyositis patients who underwent an esophagogastroduodenoscopy and/or colonoscopy. METHODS:A cross-sectional study examining the results of upper endoscopy and colonoscopy in adults with dermatomyositis at an urban, university hospital over a ten year period was performed. Chart review was performed to confirm the diagnosis of dermatomyositis. Findings on endoscopy were collected and statistical analyses stratified by age and presence of symptoms were performed. RESULTS:Among 373 adult patients identified through a code based search strategy, only 163 patients had dermatomyositis confirmed by chart review. Of the 47 patients who underwent upper endoscopy, two cases of Barrett's esophagus without dysplasia were identified and there were no cases of malignancy. Of the 67 patients who underwent colonoscopy, no cases of malignancy were identified and an adenoma was identified in 15% of cases. No significant differences were identified in the yield of endoscopy when stratified by age or presence of symptoms. CONCLUSION:The yield of endoscopy is low in patients with dermatomyositis and is likely similar to the general population; we identified no cases of malignancy. A code based search strategy is inaccurate for the diagnosis of dermatomyositis, calling into question the results of prior population-based studies. Larger studies with rigorously validated search strategies are necessary to understand the risk of gastrointestinal malignancy in patients with dermatomyositis.

journal_name

World J Gastroenterol

authors

Kidambi TD,Schmajuk G,Gross AJ,Ostroff JW,Terdiman JP,Lee JK

doi

10.3748/wjg.v23.i26.4788

subject

Has Abstract

pub_date

2017-07-14 00:00:00

pages

4788-4795

issue

26

eissn

1007-9327

issn

2219-2840

journal_volume

23

pub_type

杂志文章
  • Innovative technique of needlescopic grasper-assisted single-incision laparoscopic common bile duct exploration: A comparative study.

    abstract:AIM:To investigate the safety and feasibility of needlescopic grasper-assisted single-incision laparoscopic common bile duct exploration (nSIL-CBDE) by comparing the surgical outcomes of this technique with those of conventional laparoscopic CBDE (CL-CBDE). METHODS:We retrospectively analyzed the clinical data of pati...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i45.12857

    authors: Kim SJ,Kim KH,An CH,Kim JS

    更新日期:2015-12-07 00:00:00

  • Diagnostic value of gadobenate dimeglumine-enhanced hepatocyte-phase magnetic resonance imaging in evaluating hepatic fibrosis and hepatitis.

    abstract:AIM:To evaluate the diagnostic value of gadobenate dimeglumine (Gd-BOPTA)-enhanced hepatocyte-phase magnetic resonance imaging (MRI) in evaluating hepatic fibrosis and hepatitis. METHODS:Hepatocyte-phase images of Gd-BOPTA-enhanced MRI were retrospectively evaluated in 76 patients with chronic liver disease. These pat...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.v23.i17.3133

    authors: Li XM,Chen Z,Xiao EH,Shang QL,Ma C

    更新日期:2017-05-07 00:00:00

  • NF-kappaB and ERK-signaling pathways contribute to the gene expression induced by cag PAI-positive-Helicobacter pylori infection.

    abstract:AIM:To elucidate the sequential gene expression profile in AGS cells co-cultured with wild-type Helicobacter pylori (H pylori) as a model of H pylori-infected gastric epithelium, and to further examine the contribution of cag-pathogenicity islands (cagPAI)-coding type IV secretion system and the two pathways, nuclear f...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i39.6134

    authors: Shibata W,Hirata Y,Yoshida H,Otsuka M,Hoshida Y,Ogura K,Maeda S,Ohmae T,Yanai A,Mitsuno Y,Seki N,Kawabe T,Omata M

    更新日期:2005-10-21 00:00:00

  • Fourth-generation quinolones in the treatment of Helicobacter pylori infection: A meta-analysis.

    abstract:AIM:To assess the efficacy and safety of fourth-generation quinolones for Helicobacter pylori (H. pylori) eradication, we conducted this systematic review and meta-analysis of randomized clinical trials. METHODS:Major literature databases (PubMed, EMBASE and the Cochrane Central Register of Controlled Trials) were sea...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.3748/wjg.v24.i29.3302

    authors: An Y,Wang Y,Wu S,Wang YH,Qian X,Li Z,Fu YJ,Xie Y

    更新日期:2018-08-07 00:00:00

  • Association of NOD1 (CARD4) insertion/deletion polymorphism with susceptibility to IBD: a meta-analysis.

    abstract:AIM:To find evidences about whether NOD1/CARD4 insertion/deletion polymorphism is associated with inflammatory bowel disease by meta-analysis. METHODS:We surveyed the studies on the association of NOD1/CARD4 insertion/deletion polymorphism with inflammatory bowel disease in PubMed. Meta-analysis was performed for geno...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.3748/wjg.v16.i34.4348

    authors: Lu WG,Zou YF,Feng XL,Yuan FL,Gu YL,Li X,Li CW,Jin C,Li JP

    更新日期:2010-09-14 00:00:00

  • Perforated midgut diverticulitis: revisited.

    abstract:AIM:To study and provide data on the evolution of medical procedures and outcomes of patients suffering from perforated midgut diverticulitis. METHODS:Three data sources were used: the Medline and Google search engines were searched for case reports on one or more patients treated for perforated midgut diverticulitis ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i34.4714

    authors: Spasojevic M,Naesgaard JM,Ignjatovic D

    更新日期:2012-09-14 00:00:00

  • NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease.

    abstract:AIM:To assess whether polymorphisms in NOD2 and ATG16L1 affect cytokine responses and mycobacterium avium subspecies paratuberculosis (MAP) survival in monocytes from Crohn's disease (CD) patients. METHODS:Monocytes were isolated from peripheral blood of CD patients of known genotype for common single nucleotide polym...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i23.2829

    authors: Glubb DM,Gearry RB,Barclay ML,Roberts RL,Pearson J,Keenan JI,McKenzie J,Bentley RW

    更新日期:2011-06-21 00:00:00

  • Effect of Chaiqinchengqi decoction on sarco/endoplasmic reticulum Ca2+-ATPase mRNA expression of pancreatic tissues in acute pancreatitis rats.

    abstract:AIM:To investigate the effect of Chaiqinchengqi decoction (CQCQD) on sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) mRNA expression of pancreatic tissues in acute pancreatitis (AP) rats. METHODS:Thirty Sprague-Dawley (SD) rats were randomized into control group, AP group and CQCQD group (n = 3 x 10). The rats in the ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.2343

    authors: Xue P,Deng LH,Zhang ZD,Yang XN,Xia Q,Xiang DK,Huang L,Wan MH

    更新日期:2008-04-21 00:00:00

  • Management of psoriasis patients with hepatitis B or hepatitis C virus infection.

    abstract::The systemic therapies available for the management of Psoriasis (PsO) patients who cannot be treated with more conservative options, such as topical agents and/or phototherapy, with the exception of acitretin, can worsen or reactivate a chronic infection. Therefore, before administering immunosuppressive therapies wi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i28.6444

    authors: Bonifati C,Lora V,Graceffa D,Nosotti L

    更新日期:2016-07-28 00:00:00

  • Hepatocellular carcinoma with chronic B-type hepatitis complicated by autoimmune hemolytic anemia: a case report.

    abstract::A 57-year-old man consulted a local hospital because of a persistent slight fever. At the age of 37 years he was diagnosed having B-type hepatitis, but left the liver dysfunction untreated. Twenty years later, he was diagnosed having chronic hepatitis B, hepatocellular carcinoma (HCC) and macrocytic anemia, and referr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i32.4401

    authors: Okada T,Kubota K,Kita J,Kato M,Sawada T

    更新日期:2007-08-28 00:00:00

  • Microbial metabolites in non-alcoholic fatty liver disease.

    abstract::The prevalence of non-alcoholic fatty liver disease (NAFLD) is rising exponentially worldwide. The spectrum of NAFLD includes non-alcoholic fatty liver, non-alcoholic steatohepatitis, liver cirrhosis, and even hepatocellular carcinoma. Evidence shows that microbial metabolites play pivotal roles in the onset and progr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v25.i17.2019

    authors: Zhou D,Fan JG

    更新日期:2019-05-07 00:00:00

  • Detection of hepatitis B virus genotypes using oligonucleotide chip among hepatitis B virus carriers in Eastern China.

    abstract:AIM:To determine the genotype distribution of hepatitis B virus (HBV) with a newly oligonucleotide chip assay among the HBV carriers in Eastern China. METHODS:An assay using oligonucleotide chip was developed for detection of HBV genotypes in serum samples from HBV DNA-positive patients in Eastern China. This method i...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v13.i13.1975

    authors: Tang XR,Zhang JS,Zhao H,Gong YH,Wang YZ,Zhao JL

    更新日期:2007-04-07 00:00:00

  • Expression of protein S100A4 is a predictor of recurrence in colorectal cancer.

    abstract:AIM:To investigate the prognostic significance of S100A4 expression in colorectal cancer and its correlation with expression of E-cadherin and p53. METHODS:A cohort of archival formalin-fixed paraffin-embedded specimens was selected from 127 patients with colorectal cancer who underwent surgical resection between Apri...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i31.3897

    authors: Kwak JM,Lee HJ,Kim SH,Kim HK,Mok YJ,Park YT,Choi JS,Moon HY

    更新日期:2010-08-21 00:00:00

  • Letter to the editor: Diagnosis of erythropoietic protoporphyria with severe liver injury - a case report.

    abstract::Erythropoietic protoporphyria (EPP) is an extremely rare disease which is often unrecognized as diagnosis. In the recent article Lui et al describe a patient with a new diagnosis of EPP with severe liver injury. Approximately 5%-20% of patients with EPP develop liver manifestations. The most severe complication of EPP...

    journal_title:World journal of gastroenterology

    pub_type: 评论,信件

    doi:10.3748/wjg.v25.i30.4292

    authors: Wensink D,Wagenmakers MA,Wilson JP,Langendonk JG

    更新日期:2019-08-14 00:00:00

  • Robot-assisted one-stage resection of rectal cancer with liver and lung metastases.

    abstract::The Da Vinci Surgical System may help to overcome some of the difficulties of laparoscopy for complicated abdominal surgery. The authors of this article present a case of robot-assisted, one-stage radical resection of three tumors, including robotic anterior resection for rectal cancer, segmental hepatectomy for liver...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i9.2848

    authors: Xu JM,Wei Y,Wang XY,Fan H,Chang WJ,Ren L,Jiang W,Fan J,Qin XY

    更新日期:2015-03-07 00:00:00

  • Role of Salmonella enterica exposure in Chilean Crohn's disease patients.

    abstract:AIM:To study the association between exposure to Salmonella enterica (SE) and Crohn's disease (CD) and its clinical implications in Chilean patients. METHODS:Ninety-four unrelated Chilean CD patients from CAREI (Active Cohort Registry of Inflammatory Bowel Disease) presenting to a single inflammatory bowel disease (IB...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i35.5855

    authors: Alvarez-Lobos M,Pizarro DP,Palavecino CE,Espinoza A,Sebastián VP,Alvarado JC,Ibañez P,Quintana C,Díaz O,Kalergis AM,Bueno SM

    更新日期:2013-09-21 00:00:00

  • Bile acid increases expression of the histamine-producing enzyme, histidine decarboxylase, in gastric cells.

    abstract:AIM:To investigate the effect of bile acid on the expression of histidine decarboxylase (HDC), which is a major enzyme involved in histamine production, and gene expression of gastric transcription factors upon cooperative activation. METHODS:HDC expression was examined by immunohistochemistry, reverse transcriptase p...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i1.175

    authors: Ku HJ,Kim HY,Kim HH,Park HJ,Cheong JH

    更新日期:2014-01-07 00:00:00

  • Effect of a nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester on invasion of human colorectal cancer cell line SL-174T.

    abstract:AIM:To investigate the effect and mechanism of action of the nitric oxide synthase (NOS) inhibitor NG-nitro-L-arginine methyl ester (L-NAME) on invasion and metastasis of human colorectal cancer cell line SL-174T. METHODS:Human colorectal cancer cell line SL-174T was cultured and treated separately with four different...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i40.6385

    authors: Yu LB,Dong XS,Sun WZ,Zhao DL,Yang Y

    更新日期:2005-10-28 00:00:00

  • Early colon cancer within a diverticulum treated by magnifying chromoendoscopy and laparoscopy.

    abstract::We report a unique case of intramucosal carcinoma in a tubulovillous adenoma arising from a single diverticulum. Endoscopic mucosal resection (EMR) was carried out successfully and completely with the assistance of laparoscopy. A 71-year-old man was admitted to our hospital because of melena and anemia. Emergent colon...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i12.1545

    authors: Fu KI,Hamahata Y,Tsujinaka Y

    更新日期:2010-03-28 00:00:00

  • Comparative study of omeprazole, lansoprazole, pantoprazole and esomeprazole for symptom relief in patients with reflux esophagitis.

    abstract:AIM:To clarify whether there is any difference in the symptom relief in patients with reflux esophagitis following the administration of four Proton pump inhibitors (PPIs). METHODS:Two hundred and seventy-four patients with erosive reflux esophagitis were randomized to receive 8 wk of 20 mg omeprazole (n = 68), 30 mg ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3748/wjg.15.990

    authors: Zheng RN

    更新日期:2009-02-28 00:00:00

  • Cholesterol crystal binding of biliary immunoglobulin A: visualization by fluorescence light microscopy.

    abstract:AIM:To assess potential contributions of biliary IgA for crystal agglomeration into gallstones, we visualized cholesterol crystal binding of biliary IgA. METHODS:Crystal binding biliary proteins were extracted from human gallbladder bile using lectin affinity chromatography.Biliary IgA was isolated from the bound prot...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v7.i2.198

    authors: Lammert F,Südfeld S,Busch N,Matern S

    更新日期:2001-04-01 00:00:00

  • Upregulation of 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase by butyrate in Caco-2 cells.

    abstract:AIM:To investigate the possible involvement of 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase [1alpha-25(OH) (2) D(3)] in butyrate-induced differentiation in human intestinal cell line Caco-2 cells. METHODS:Caco-2 cells were incubated either with 3 mmol/L butyrate and 1 micromol/L 25(OH) (2) D(3) or with 1 micromol/L 1al...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i45.7136

    authors: Schröder O,Turak S,Daniel C,Gaschott T,Stein J

    更新日期:2005-12-07 00:00:00

  • Small intestinal vascular malformation bleeding: a case report with imaging findings.

    abstract::The small intestine is approximately 5-6 m long and occupies a large area in the abdominal cavity. These factors preclude the use of ordinary endoscopy and X-ray to thoroughly examine the small intestine for bleeding of vascular malformations. Thus, the diagnosis of intestinal bleeding is very difficult. A 47-year-old...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i38.14076

    authors: Cui J,Huang LY,Lin SJ,Yi LZ,Wu CR,Zhang B

    更新日期:2014-10-14 00:00:00

  • Preventive treatments for recurrence after curative resection of hepatocellular carcinoma--a literature review of randomized control trials.

    abstract::To review the inhibitory effect of preventive approaches on recurrence after operation in patients with hepatocellular carcinoma (HCC), we summarized all available publications reporting randomized control trial indexed in PubMed. The treatment approaches presented above included pre-operative transcatheter arterial c...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v9.i4.635

    authors: Sun HC,Tang ZY

    更新日期:2003-04-01 00:00:00

  • Therapeutic advances: single incision laparoscopic hepatopancreatobiliary surgery.

    abstract::Single-port laparoscopic surgery (SPLS) is proposed to be a step towards minimizing the invasiveness of surgery, and has since gained popularity in several surgical sub-specialties including hepatopancreatobiliary surgery. SPLS has since been applied to cholecystectomy, liver resection as well as pancreatectomy for a ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i39.14329

    authors: Chang SK,Lee KY

    更新日期:2014-10-21 00:00:00

  • Effect of probiotics on pro-inflammatory cytokines and NF-kappaB activation in ulcerative colitis.

    abstract:AIM:To demonstrate the therapeutic effect of probiotics in patients with ulcerative colitis (UC), and their effect on inflammatory mediators and nuclear factor (NF)-kappaB activation in these patients. METHODS:Thirty patients with mild to moderate UC were randomly classified into two groups: sulfasalazine group, who r...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3748/wjg.v16.i33.4145

    authors: Hegazy SK,El-Bedewy MM

    更新日期:2010-09-07 00:00:00

  • Recent developments on the role of Clostridium difficile in inflammatory bowel disease.

    abstract::Clostridium difficile (CD), specifically its toxins, have been implicated as a risk factor for exacerbation of the inflammatory process in up to 5% of patients with ulcerative colitis or Crohnos disease. Typical evidence of colonic changes with CD infection, including pseudomembranous exudate, are often not present; h...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.2794

    authors: Freeman HJ

    更新日期:2008-05-14 00:00:00

  • Impact of disease severity on gastric residual volume in critical patients.

    abstract:AIM:To investigate whether illness severity has an impact on gastric residual volume (GRV) in medical critically ill patients. METHODS:Medical intensive care unit (ICU) patients requiring nasogastric feeding were enrolled. Sequential Organ Failure Assessment (SOFA) score was assessed immediately preceding the start of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i15.2007

    authors: Hsu CW,Sun SF,Lee DL,Lin SL,Wong KF,Huang HH,Li HJ

    更新日期:2011-04-21 00:00:00

  • Bacterial flora concurrent with Helicobacter pylori in the stomach of patients with upper gastrointestinal diseases.

    abstract:AIM:To investigate the non-Helicobacter pylori (H. pylori) bacterial flora concurrent with H. pylori infection. METHODS:A total of 103 gastric biopsy specimens from H. pylori positive patients were selected for bacterial culture. All the non-H. pylori bacterial isolates were identified by matrix-assisted laser desorpt...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i11.1257

    authors: Hu Y,He LH,Xiao D,Liu GD,Gu YX,Tao XX,Zhang JZ

    更新日期:2012-03-21 00:00:00

  • Laparoscopic partial resection for hemangioma in the third portion of the duodenum.

    abstract::Benign duodenal tumors are rare and less common than malignant tumors. Furthermore, vascular lesions of the duodenum, including hemangiomas, are rare causes of gastrointestinal bleeding. This report describes a case with bleeding hemangiomas in the third portion of the duodenum and jejunum and their successful treatme...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i34.12341

    authors: Kanaji S,Nakamura T,Nishi M,Yamamoto M,Kanemitu K,Yamashiita K,Imanishi T,Sumi Y,Suzuki S,Tanaka K,Kakeji Y

    更新日期:2014-09-14 00:00:00