Abstract:
:Clostridium difficile (CD), specifically its toxins, have been implicated as a risk factor for exacerbation of the inflammatory process in up to 5% of patients with ulcerative colitis or Crohnos disease. Typical evidence of colonic changes with CD infection, including pseudomembranous exudate, are often not present; however, a severe clinical course may result, including precipitation of toxic colitis and toxic megacolon. Recently, hypervirulent CD strains have been reported raising concern for a more severe disease process in patients with underlying inflammatory bowel disease. Moreover, small bowel involvement or CD enteritis has been increasingly described, usually in those with a history of a prior colectomy or total proctocolectomy for prior severe and extensive inflammatory bowel disease. Finally, refractory or treatment-resistant pouchitis may occur with CD infection.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Freeman HJdoi
10.3748/wjg.14.2794subject
Has Abstractpub_date
2008-05-14 00:00:00pages
2794-6issue
18eissn
1007-9327issn
2219-2840journal_volume
14pub_type
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journal_title:World journal of gastroenterology
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
doi:10.3748/wjg.v8.i5.908
更新日期:2002-10-01 00:00:00
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journal_title:World journal of gastroenterology
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pub_type: 杂志文章,评审
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journal_title:World journal of gastroenterology
pub_type: 杂志文章,评审
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更新日期:2001-08-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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