Pleiotropic effects of statins in the diseases of the liver.

abstract：AIM:To investigate the gastrin secreting cells (G cells) and the somatostatin secreting cells (D cells) of antral mucosa in rats at the ultrastructural level. METHODS:Revised immunoelectron microscopic technique was used to detect the G cells and D cells in rat antral mucosa through gastrin and somatostatin antibodies...

journal_title：World journal of gastroenterology

authors： Sun FP,Song YG

更新日期：2003-12-01 00:00:00

abstract：:A number of alterations have been found within the gut microbial profile of patients with inflammatory bowel diseases when compared with the healthy population; however, it is unclear whether such dysbiosis is the cause or simply the consequence of the disease state. In ulcerative colitis, the environment seems to pla...

journal_title：World journal of gastroenterology

authors： Sorrentino D

更新日期：2017-10-07 00:00:00

abstract：AIM:To determine the expression characteristics of connective tissue growth factor (CTGF/CCN2) in human hepatocellular carcinoma (HCC) in histology and to elucidate the roles of CCN2 on hepatoma cell cycle progression and metastasis in vitro. METHODS:Liver samples from 36 patients (who underwent hepatic resection for ...

journal_title：World journal of gastroenterology

authors： Xiu M,Liu YH,Brigstock DR,He FH,Zhang RJ,Gao RP

更新日期：2012-12-21 00:00:00

abstract：:AIM:To determine whether recombinant human epidermal growth factor (rhEGF) can protect gastric mucosa against ethanol induced injury in rats.METHOD: Fifty-four SD rats weighing 200g-500g each were divided into six groups after fasting for 24 hours.Three groups received different doses of oral rhEGF (30, 60 and 120&mgr...

journal_title：World journal of gastroenterology

authors： Xu CD,Gan RB,Chen SN,Jiang SH,Xu JY

更新日期：1998-10-01 00:00:00

abstract：AIM:To investigate the diagnostic accuracy of acoustic radiation force impulse (ARFI) imaging as a noninvasive method for the assessment of liver fibrosis in chronic hepatitis C (CHC) patients. METHODS:We performed a prospective blind comparison of ARFI elastography, APRI index and FibroMax in a consecutive series of ...

journal_title：World journal of gastroenterology

authors： Fierbinteanu-Braticevici C,Andronescu D,Usvat R,Cretoiu D,Baicus C,Marinoschi G

更新日期：2009-11-28 00:00:00

abstract：AIM:To investigate the association of seven single nucleotide polymorphisms (SNPs) of the IL23R gene with the clinical picture of ulcerative colitis (UC). METHODS:Genomic DNA samples of 131 patients (66 males, 65 females, mean age 55.4 ± 15.8 years) with Caucasian origin, diagnosed with UC were investigated. The diagn...

journal_title：World journal of gastroenterology

authors： Fischer S,Kövesdi E,Magyari L,Csöngei V,Hadzsiev K,Melegh B,Hegyi P,Sarlós P

更新日期：2017-01-21 00:00:00

abstract：AIM:To carry out a hospital-based case-control study to investigate risk factors for intrahepatic cholangiocarcinoma (ICC) in China. METHODS:A total of 312 ICC cases and 438 matched controls were included in the study. The presence of diabetes mellitus, hypertension, hepatolithiasis, primary sclerosing cholangitis, li...

journal_title：World journal of gastroenterology

authors： Zhou YM,Yin ZF,Yang JM,Li B,Shao WY,Xu F,Wang YL,Li DQ

更新日期：2008-01-28 00:00:00

abstract：BACKGROUND:Small-for-size grafts (SFSGs) in living donor liver transplantation (LDLT) could optimize donor postoperative outcomes and also expand the potential donor pool. Evidence on whether SFSGs would affect medium-term and long-term recipient graft survival is lacking. AIM:To evaluate the impact of small-for-size ...

journal_title：World journal of gastroenterology

authors： Ma KW,Wong KHC,Chan ACY,Cheung TT,Dai WC,Fung JYY,She WH,Lo CM,Chok KSH

更新日期：2019-09-28 00:00:00

abstract：BACKGROUND:The Korea National Cancer Screening Program currently provides screening for colorectal cancer (CRC) for adults older than 50 years with no upper age limit. In general, people are likely to only pay attention to the benefits of cancer screening and to neglect its risks. Most consider the benefits of cancer s...

journal_title：World journal of gastroenterology

authors： Luu XQ,Lee K,Lee YY,Suh M,Kim Y,Choi KS

更新日期：2020-07-21 00:00:00

abstract：AIM:Non-bioartificial liver has been applied to clinic for quite a long time, but the reported efficacy has been very different. The aim of this study was to compare the efficacy and safety of hemoperfusion adsorption, plasma exchange and plasma exchange plus hemoperfusion adsorption in treatment of severe viral hepati...

journal_title：World journal of gastroenterology

authors： He NH,Wang YJ,Wang ZW,Liu J,Li JJ,Liu GD,Wang YM

更新日期：2004-04-15 00:00:00

abstract：AIM:To investigate whether illness severity has an impact on gastric residual volume (GRV) in medical critically ill patients. METHODS:Medical intensive care unit (ICU) patients requiring nasogastric feeding were enrolled. Sequential Organ Failure Assessment (SOFA) score was assessed immediately preceding the start of...

journal_title：World journal of gastroenterology

authors： Hsu CW,Sun SF,Lee DL,Lin SL,Wong KF,Huang HH,Li HJ

更新日期：2011-04-21 00:00:00

abstract：AIM:To determine the in vivo and in vivo effects of cysteamine (CS) on expression and activity of H(+)-K(+)-ATPase of gastric mucosal cells in weaning piglets. METHODS:Eighteen litters of newborn Xinhuai piglets were employed in the in vivo experiment and allocated to control and treatment groups. From 12 d of age (D1...

journal_title：World journal of gastroenterology

authors： Shi ZM,Du GM,Wei XH,Zhang L,Chen J,Zhao RQ

更新日期：2005-11-14 00:00:00

abstract：:The paper provides a basic review of intestinal microflora and its importance in liver diseases. The intestinal microflora has many important functions, above all to maintain the microbial barrier against established as well as potential pathogens. Furthermore, it influences the motility and perfusion of the intestina...

journal_title：World journal of gastroenterology

authors： Lata J,Jurankova J,Kopacova M,Vitek P

更新日期：2011-06-28 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) encompasses a range of liver histology severity and outcomes in the absence of chronic alcohol use. The mildest form is simple steatosis in which triglycerides accumulate within hepatocytes. A more advanced form of NAFLD, non-alcoholic steatohepatitis, includes inflammation and...

journal_title：World journal of gastroenterology

authors： Pacifico L,Nobili V,Anania C,Verdecchia P,Chiesa C

更新日期：2011-07-14 00:00:00

abstract：AIM:To investigate the role of peritoneal macrophage (PM) polarization in the therapeutic effect of abdominal paracentesis drainage (APD) on severe acute pancreatitis (SAP). METHODS:SAP was induced by 5% Na-taurocholate retrograde injection in Sprague-Dawley rats. APD was performed by inserting a drainage tube with a ...

journal_title：World journal of gastroenterology

authors： Liu RH,Wen Y,Sun HY,Liu CY,Zhang YF,Yang Y,Huang QL,Tang JJ,Huang CC,Tang LJ

更新日期：2018-12-07 00:00:00

abstract：BACKGROUND:The human microRNA 375 (MIR375) is significantly downregulated in human colorectal cancer (CRC) and we have previously shown that MIR375 is a CRC-associated miRNA. The metadherin (MTDH) is a candidate target gene of MIR375. AIM:To investigate the interaction and function between MIR375 and MTDH in human CRC...

journal_title：World journal of gastroenterology

authors： Han SH,Mo JS,Park WC,Chae SC

更新日期：2019-11-28 00:00:00

abstract：AIM:To evaluate the impact of therapeutic education on adherence to antiviral treatment and sustained virological response (SVR) in a real-life setting in genotype 2/3 hepatitis C, as there are few adherence data in genotype 2/3 infection, even from randomized trials. METHODS:This prospective survey included genotype ...

journal_title：World journal of gastroenterology

authors： Cacoub P,Ouzan D,Melin P,Lang JP,Rotily M,Fontanges T,Varastet M,Chousterman M,Marcellin P

更新日期：2008-10-28 00:00:00

abstract：:Alterations of normal function of interstitial cells of Cajal (ICC) are reported in many intestinal disorders. Diagnosis of their involvement is rare (infrequent), but necessary to propose a specific treatment. This article reviews the place of ICC in the pathogenesis of achalasia, gastroesophageal reflux disease, inf...

journal_title：World journal of gastroenterology

authors： Negreanu LM,Assor P,Mateescu B,Cirstoiu C

更新日期：2008-11-07 00:00:00

abstract：AIM:To evaluate the effects of omeprazole on gastric mechanosensitivity in humans. METHODS:A double lumen polyvinyl tube with a plastic bag was introduced into the stomach of healthy volunteers under fluorography and connected to a barostat device. Subjects were then positioned so they were sitting comfortably, and th...

journal_title：World journal of gastroenterology

authors： Iida A,Kaneko H,Konagaya T,Funaki Y,Tokudome K,Izawa S,Tamura Y,Mizuno M,Ogasawara N,Sasaki M,Kasugai K

更新日期：2012-10-21 00:00:00

abstract：AIM:To investigate the effects of herbal compound 861 (Cpd 861) on cell proliferation in human hepatic stellate cells (LX-2) and human hepatocellular liver carcinoma cells (HepG2), and expression of alpha-smooth muscle actin (alpha-SMA) in LX-2 cells. METHODS:LX-2 and HepG2 cells were incubated with various concentrat...

journal_title：World journal of gastroenterology

authors： Wang L,Wang J,Wang BE,Xiao PG,Qiao YJ,Tan XH

更新日期：2004-10-01 00:00:00

abstract：AIM:To study the expression of vascular endothelial growth factor A (VEGF-A) and VEGF-C and to determine whether the presence of VEGF-A and VEGF-C was associated with the clinicopathologic characteristics of pancreatic cancer. METHODS:VEGF-A and VEGF-C mRNA transcripts were examined by Northern blot in 6 human pancrea...

journal_title：World journal of gastroenterology

authors： Tang RF,Wang SX,Peng L,Wang SX,Zhang M,Li ZF,Zhang ZM,Xiao Y,Zhang FR

更新日期：2006-01-14 00:00:00

abstract：AIM:Inducible nitric oxide synthase (iNOS) plays a central role in the pathway of reactive oxygen and nitrogen species metabolism when Helicobacter pylori (H pylori) infection occurs in humans. iNOS Ser(608)Leu allele, a novel genetic polymorphism (C/T) occurring within exon 16 of the iNOS reductase domain, may have a ...

journal_title：World journal of gastroenterology

authors： Shen J,Wang RT,Wang LW,Xu YC,Wang XR

更新日期：2004-11-15 00:00:00

abstract：:Solitary fibrous tumors are predominantly benign and are most commonly found in the thoracic cavity and pleura; while reports exist in the literature of malignant solitary fibrous tumors and those located in extrathoracic organs, these cases are considered extremely rare. Herein, a case is reported of a malignant soli...

journal_title：World journal of gastroenterology

authors： Jakob M,Schneider M,Hoeller I,Laffer U,Kaderli R

更新日期：2013-06-07 00:00:00

abstract：AIM:To study the effects of palmatine, a known inhibitor on delayed rectifier potassium current and L-type calcium current (I(Ca,L)) in guinea pig ventricular myocytes, on the potassium and calcium currents in isolated rat hepatocytes. METHODS:Tight-seal whole-cell patch-clamp techniques were performed to investigate ...

journal_title：World journal of gastroenterology

authors： Wang F,Zhou HY,Cheng L,Zhao G,Zhou J,Fu LY,Yao WX

更新日期：2003-02-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) results from a complex series of interactions between susceptibility genes, the environment, and the immune system. Recently, some studies provided strong evidence that the process of autophagy affects several aspects of mucosal immune responses. Autophagy is a cellular stress response...

journal_title：World journal of gastroenterology

authors： Iida T,Onodera K,Nakase H

更新日期：2017-03-21 00:00:00

abstract：:Patients with inflammatory bowel disease (IBD) can be affected by other unrelated diseases. These are called comorbid conditions, and can include any secondary health problem that affects a person suffering from a primary or main disease, and which is neither linked physiopathologically to the primary condition, nor i...

journal_title：World journal of gastroenterology

authors： Román AL,Muñoz F

更新日期：2011-06-14 00:00:00

abstract：AIM:To investigate protective effects and molecular mechanisms of green tea polyphenols (GTP) on non-alcoholic fatty liver disease (NAFLD) in Zucker fatty (ZF) rats. METHODS:Male ZF rats were fed a high-fat diet (HFD) for 2 wk then treated with GTP (200 mg/kg) or saline (5 mL/kg) for 8 wk, with Zucker lean rat as thei...

journal_title：World journal of gastroenterology

authors： Tan Y,Kim J,Cheng J,Ong M,Lao WG,Jin XL,Lin YG,Xiao L,Zhu XQ,Qu XQ

更新日期：2017-06-07 00:00:00

abstract：:Since the development of uncovered self-expanding metal stents (SEMS) in the 1990s, endoscopic stents have evolved dramatically. Application of new materials and new designs has expanded the indications for enteral SEMS. At present, enteral stents are considered the first-line modality for palliative care, and numerou...

journal_title：World journal of gastroenterology

authors： Kim EJ,Kim YJ

更新日期：2016-01-14 00:00:00

abstract：:Endoclip migration into the common bile duct following laparoscopic cholecystectomy (LC) is an extremely rare complication. Migrated endoclip into the common bile duct can cause obstruction, serve as a nidus for stone formation, and cause cholangitis. We report a case of obstructive jaundice and acute biliary pancreat...

journal_title：World journal of gastroenterology

authors： Dolay K,Alis H,Soylu A,Altaca G,Aygun E

更新日期：2007-12-21 00:00:00

abstract：AIM:To determine the incidence of peripheral fractures in patients with celiac disease (CD) and the effect of treatment on fracture risk. METHODS:We compared the incidence and risk of peripheral fractures before and after diagnosis between a cohort of 265 patients who had been diagnosed with CD at least 5 years before...

journal_title：World journal of gastroenterology

authors： Sánchez MI,Mohaidle A,Baistrocchi A,Matoso D,Vázquez H,González A,Mazure R,Maffei E,Ferrari G,Smecuol E,Crivelli A,de Paula JA,Gómez JC,Pedreira S,Mauriño E,Bai JC

更新日期：2011-07-07 00:00:00