Interstitial cells of Cajal in the gut--a gastroenterologist's point of view.

abstract：AIM:To determine the frequency of HER2/neu protein overexpression in gastric (group A), small intestine (group B), and colorectal (group C) adenocarcinoma. METHODS:A descriptive, cross-sectional study was performed on 50 cases of gastrointestinal adenocarcinoma (stomach, small intestine, and colorectal); 11 from group...

journal_title：World journal of gastroenterology

authors： Farzand S,Siddique T,Saba K,Bukhari MH

更新日期：2014-05-21 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a highly invasive tumor that metastasizes hematogenously and lymphogenously to distant site. Frequent sites are lung, regional lymph node, bone, and adrenal gland. But metastasis to the gastrointestinal (GI) tract is rare, and most common site is stomach. Metastasis to the small intes...

journal_title：World journal of gastroenterology

authors： Kim HS,Shin JW,Kim GY,Kim YM,Cha HJ,Jeong YK,Jeong ID,Bang SJ,Kim DH,Park NH

更新日期：2006-03-28 00:00:00

abstract：AIM:To investigate GATA5, SFRP2, and ITGA4 methylation in plasma DNA as noninvasive biomarkers for colorectal cancer (CRC) or adenomas. METHODS:There were 57 CRC patients, 30 adenomas patients, and 47 control patients enrolled in this study. Methylation-specific polymerase chain reaction was used to determine the prom...

journal_title：World journal of gastroenterology

authors： Zhang X,Song YF,Lu HN,Wang DP,Zhang XS,Huang SL,Sun BL,Huang ZG

更新日期：2015-03-07 00:00:00

abstract：:Cancer is currently one of the most important public health problems in the world. Pancreatic cancer is a fatal disease with poor prognosis. As in most other countries, the health burden of pancreatic cancer in China is increasing, with annual mortality rates almost equal to incidence rates. The increasing trend of pa...

journal_title：World journal of gastroenterology

authors： Lin QJ,Yang F,Jin C,Fu DL

更新日期：2015-07-14 00:00:00

abstract：AIM:To evaluate the levels of preoperative serum matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in gastric cancer. METHODS:One hundred gastric cancer patients who underwent gastrectomy were enrolled in this study. The serum concentrations of MMP-1 and TIMP-1 in these patients a...

journal_title：World journal of gastroenterology

authors： Kemik O,Kemik AS,Sümer A,Dulger AC,Adas M,Begenik H,Hasirci I,Yilmaz O,Purisa S,Kisli E,Tuzun S,Kotan C

更新日期：2011-04-28 00:00:00

abstract：AIM:To study the epidemiology of gastric malignancies in Jordan as a model for Middle East countries where such data is scarce. METHODS:Pertinent epidemiological and clinicopathological data for 201 patients with gastric malignancy in north of Jordan between 1991 and 2001 were analyzed. RESULTS:Male: female ratio was...

journal_title：World journal of gastroenterology

authors： Bani-Hani KE,Yaghan RJ,Heis HA,Shatnawi NJ,Matalka II,Bani-Hani AM,Gharaibeh KA

更新日期：2004-08-01 00:00:00

abstract：AIM:To examine the potency of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) as a hepatic heme oxygenase-1 (HO-1) inducer and its regulation in HepG2 cells. METHODS:Expression of HO-1 and NF-E2-related factor 2 (Nrf2) and activation of mitogen-activated protein (MAP) kinases were analyzed by Western blot, immunofluore...

journal_title：World journal of gastroenterology

authors： Pae HO,Oh GS,Jeong SO,Jeong GS,Lee BS,Choi BM,Lee HS,Chung HT

更新日期：2006-01-14 00:00:00

abstract：AIM:To evaluate the clinical relevance of each cofactor on clinical presentation of chronic hepatitis B. METHODS:Out of 1366 hepatitis B surface antigen (HBsAg) positive subjects consecutively observed in 79 Italian hospitals, 53 (4.3%) showed as the only cofactor hepatitis D virus (HDV) infection [hepatitis B virus (...

journal_title：World journal of gastroenterology

authors： Sagnelli E,Stroffolini T,Mele A,Imparato M,Sagnelli C,Coppola N,Almasio PL

更新日期：2012-04-14 00:00:00

abstract：:Transplantation cannot be considered the most important therapeutic procedure for hepatocellular carcinoma (HCC). In France, no more than 2% of patients with HCC undergo a transplantation. Randomized controlled trial must assess the benefit to risk ratio of various potentially "curative" treatment procedures (transpla...

journal_title：World journal of gastroenterology

authors： Braillon A

更新日期：2009-11-14 00:00:00

abstract：AIM:To assess the efficiency of endoscopic trans-esophageal submucosal tunneling surgery (EESTS) technique for diseases located around the aorta ventralis. METHODS:Nine pigs were assigned to EESTs. The procedures were as follows: First, a long esophageal submucosal tunnel was established. Second, full-thickness myotom...

journal_title：World journal of gastroenterology

authors： Xiong Y,Chen QQ,Chai NL,Jiao SC,Ling Hu EQ

更新日期：2019-01-07 00:00:00

abstract：AIM:To assess the clinicopathological and biological significance of cripto in human colorectal cancer. METHODS:Real-time reverse-transcription polymerase chain reaction (PCR) was used to examine cripto mRNA levels in primary colon cancer and normal colon tissues as well as normal and metastatic lymph nodes from colon...

journal_title：World journal of gastroenterology

authors： Jiang PC,Zhu L,Fan Y,Zhao HL

更新日期：2013-12-14 00:00:00

abstract：AIM:To evaluate the predictive value of tissue transglutaminase (tTG) antibodies for villous atrophy in adult and pediatric populations to determine if duodenal biopsy can be avoided. METHODS:A total of 324 patients with celiac disease (CD; 97 children and 227 adults) were recruited prospectively at two tertiary cente...

journal_title：World journal of gastroenterology

authors： Vivas S,Ruiz de Morales JG,Riestra S,Arias L,Fuentes D,Alvarez N,Calleja S,Hernando M,Herrero B,Casqueiro J,Rodrigo L

更新日期：2009-10-14 00:00:00

abstract：:The main treatment of patients with non-alcoholic fatty liver disease (NAFLD) is life style modification including weight reduction and dietary regimen. Majority of patients are safely treated with this management and pharmacologic interventions are not recommended. However, a subgroup of NAFLD patients with non-alcoh...

journal_title：World journal of gastroenterology

authors： Eshraghian A

更新日期：2017-11-14 00:00:00

abstract：AIM:To investigate the relationship between glucose metabolism and glypican-3 (GPC3) expression in hepatocellular carcinoma (HCC). METHODS:Immunohistochemical staining of pathological samples for GPC3 and glucose transporter 1 (GLUT1), and whole-body 18F-FDG PET/CT for measuring tumour glucose uptake were performed in...

journal_title：World journal of gastroenterology

authors： Li YC,Yang CS,Zhou WL,Li HS,Han YJ,Wang QS,Wu HB

更新日期：2018-01-28 00:00:00

abstract：AIM:To investigate the clinical value of ultrasonographic diagnosis of biliary atresia (BA), a retrospective analysis of the sonogram of 20 children with BA was undertaken. METHODS:Ultrasonography (US) was performed in 20 neonates and infants with BA, which was confirmed with cholangiography by operation or abdominosc...

journal_title：World journal of gastroenterology

authors： Li SX,Zhang Y,Sun M,Shi B,Xu ZY,Huang Y,Mao ZQ

更新日期：2008-06-14 00:00:00

abstract：AIM:To investigate the prevalence of erectile dysfunction (ED) and its association with depression in patients with chronic viral hepatitis. METHODS:This single center cross-sectional study was conducted from August 2013 through January 2014. All outpatients with chronic viral hepatitis in our liver clinic between 18 ...

journal_title：World journal of gastroenterology

authors： Ma BO,Shim SG,Yang HJ

更新日期：2015-05-14 00:00:00

abstract：:We report a 31-year-old woman with Crohn's disease complicated by multiple stenoses and internal fistulas clinically misdiagnosed as small bowel endometriosis, due to the patient's perimenstrual symptoms of mechanical subileus for 3 years; at first monthly, but later continuous, and gradually increasing in severity. W...

journal_title：World journal of gastroenterology

authors： Teke Z,Aytekin FO,Atalay AO,Demirkan NC

更新日期：2008-01-07 00:00:00

abstract：AIM:To identify the incidence and etiology of anemia after gastrectomy in patients with long-term follow-up after gastrectomy for early gastric cancer. METHODS:The medical records of those patients with early gastric adenocarcinoma who underwent curative gastrectomy between January 2006 and October 2007 were reviewed....

journal_title：World journal of gastroenterology

authors： Lim CH,Kim SW,Kim WC,Kim JS,Cho YK,Park JM,Lee IS,Choi MG,Song KY,Jeon HM,Park CH

更新日期：2012-11-14 00:00:00

abstract：:Hepatitis C is recognized as a major threat to global public health. The current treatment of patients with chronic hepatitis C is the addition of ribavirin to interferon-based therapy which has limited efficacy, poor tolerability, and significant expense. New treatment options that are more potent and less toxic are ...

journal_title：World journal of gastroenterology

authors： Khattab MA

更新日期：2009-07-28 00:00:00

abstract：AIM:To investigate whether butyrate or glutamine enemas could diminish inflammation in experimental diversion colitis. METHODS:Wistar specific pathogen-free rats were submitted to a Hartmann's end colostomy and treated with enemas containing glutamine, butyrate, or saline. Enemas were administered twice a week in the ...

journal_title：World journal of gastroenterology

authors： Pacheco RG,Esposito CC,Müller LC,Castelo-Branco MT,Quintella LP,Chagas VL,de Souza HS,Schanaider A

更新日期：2012-08-28 00:00:00

abstract：:The diagnosis of early gastric cancer (EGC) is of great interest because its endoscopic and surgical treatment presents the best chance for a cure. With technical development, endoscopic submucosal dissection (ESD) has been widely performed for the curative treatment of EGC in Korea. Multinational studies of ESD for E...

journal_title：World journal of gastroenterology

authors： Cho WY,Cho JY,Chung IK,Kim JI,Jang JS,Kim JH

更新日期：2011-06-07 00:00:00

abstract：AIM:To investigate the risk association and compare the onset age of hepatocellular carcinoma (HCC) patients in Taiwan with different genotypes of MDM2-SNP309. METHODS:We analyzed MDM2-SNP309 genotypes from 58 patients with HCC and 138 cancer-free healthy controls consecutively. Genotyping of MDM2-SNP309 was conducted...

journal_title：World journal of gastroenterology

authors： Leu JD,Lin IF,Sun YF,Chen SM,Liu CC,Lee YJ

更新日期：2009-11-28 00:00:00

abstract：:Successful cannulation of the common bile duct may be difficult in patients in whom the papilla is located entirely within a diverticulum. In this study, we report successful biliary cannulation in three patients following intubation of the distal tip of the duodenoscope into the duodenal diverticulum and locating the...

journal_title：World journal of gastroenterology

authors： Wang BC,Shi WB,Zhang WJ,Gu J,Tao YJ,Wang YQ,Wang XF

更新日期：2012-12-28 00:00:00

abstract：AIM:To analyze the clinicopathologic characteristics and prognostic factors of rectal neuroendocrine tumors. METHODS:The records of 48 patients with rectal neuroendocrine tumors who were treated at the Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing, from March 2004 to September 2009 were r...

journal_title：World journal of gastroenterology

authors： Chi Y,Du F,Zhao H,Wang JW,Cai JQ

更新日期：2014-11-21 00:00:00

abstract：:The overall survival for patients with advanced hepatocellular carcinoma (HCC) is still limited. Although the multi-kinase inhibitor sorafenib has recently been approved for this disease, response rates are still low and patients often face dose-limiting toxicities which lead to a reduction in prognosis and treatment ...

journal_title：World journal of gastroenterology

authors： Wich C,Agaimy A,Strobel D,Wissniowski TT,Hartmann A,Ocker M

更新日期：2010-07-28 00:00:00

abstract：AIM:To investigate omeprazole-induced transepithelial gastric leak and its effects on the permeability of the peptides bradykinin and oxytocin. METHODS:Rat gastric corpus tissue was isolated and mounted in an Ussing chamber apparatus to evaluate the permeability of (3)H-bradykinin, (3)H-oxytocin, and (14)C-EDTA in the...

journal_title：World journal of gastroenterology

authors： Gabello M,Valenzano MC,Zurbach EP,Mullin JM

更新日期：2010-03-07 00:00:00

abstract：:P21-activated kinases (PAKs) are central players in various oncogenic signaling pathways. The six PAK family members are classified into group I (PAK1-3) and group II (PAK4-6). Focus is currently shifting from group I PAKs to group II PAKs. Group II PAKs play important roles in many fundamental cellular processes, som...

journal_title：World journal of gastroenterology

authors： Shao YG,Ning K,Li F

更新日期：2016-01-21 00:00:00

abstract：:Hepatitis B virus (HBV) is the leading cause of liver disease and infects an estimated 240 million people worldwide. It is characterised by a high degree of genetic heterogeneity because of the use of a reverse transcriptase during viral replication. The ten genotypes (A-J) that have been described so far further segr...

journal_title：World journal of gastroenterology

authors： Zehender G,Ebranati E,Gabanelli E,Sorrentino C,Lo Presti A,Tanzi E,Ciccozzi M,Galli M

更新日期：2014-06-28 00:00:00

abstract：AIM:To investigate the roles of the adipocytokines, ghrelin and leptin in gastric cancer cachexia. METHODS:Resistin, ghrelin, leptin, adiponectin, insulin and insulin-like growth factor (IGF-I), were measured in 30 healthy subjects, and 60 gastric cancer patients of which 30 suffered from cancer-induced cachexia and 3...

journal_title：World journal of gastroenterology

authors： Kerem M,Ferahkose Z,Yilmaz UT,Pasaoglu H,Ofluoglu E,Bedirli A,Salman B,Sahin TT,Akin M

更新日期：2008-06-21 00:00:00

abstract：AIM:To characterise the viral kinetics of enterovirus 71 (EV71). METHODS:In this study, human rhabdomyosarcoma (RD) cells were infected with EV71 at different multiplicity of infection (MOI). After infection, the cytopathic effect (CPE) was monitored and recorded using a phase contrast microscope associated with a CCD...

journal_title：World journal of gastroenterology

authors： Lu J,He YQ,Yi LN,Zan H,Kung HF,He ML

更新日期：2011-09-28 00:00:00