Enigmatic origin of hepatitis B virus: an ancient travelling companion or a recent encounter?

abstract：BACKGROUND:Esophageal cancer is one of the most common cancers around the world, and it has high incidence and mortality rates. The conventional therapy for esophageal cancer is radiotherapy, although its effect is highly limited by the resistance of esophageal cancer cells. Thus, strong radiosensitizers can be very cr...

journal_title：World journal of gastroenterology

authors： Qiu ZH,Zhang WW,Zhang HH,Jiao GH

更新日期：2019-05-28 00:00:00

abstract：AIM:To discuss the rationality of extended radical resection (ERR) and to guide the surgical treatment of rectal cancer. METHODS:Total 211 patients who underwent ERR from 1981 to 1987 (follow-up rate of 94.8 %) were selected to study the patterns of lymphatic metastasis and therapeutic effect. The control group was ma...

journal_title：World journal of gastroenterology

authors： Dong XS,Xu HT,Yu ZW,Liu M,Cu BB,Zhao P,Wang XS

更新日期：2003-05-01 00:00:00

abstract：:Bowel preparation is a core issue in colonoscopy, as it is closely related to the quality of the procedure. Patients often find that bowel preparation is the most unpleasant part of the examination. It is widely accepted that the quality of cleansing must be excellent to facilitate detecting neoplastic lesions. In spi...

journal_title：World journal of gastroenterology

authors： Parra-Blanco A,Ruiz A,Alvarez-Lobos M,Amorós A,Gana JC,Ibáñez P,Ono A,Fujii T

更新日期：2014-12-21 00:00:00

abstract：AIM:To study immune response induced by foreign plasmid DNA after oral administration in mice. METHODS:Mice were orally administered with 200 mug of plasmid pcDNA3 once and spleen was isolated 4 h and 18 h after administration. Total RNA was extracted from spleen and gene expression profile of BALB/c mice spleen was a...

journal_title：World journal of gastroenterology

authors： Liu JW,Cheng J

更新日期：2007-07-28 00:00:00

abstract：AIM:To investigate the correlation between the serum soluble intercellular adhesion molecule-1 (sICAM-1) and the clinicopathologic features and to evaluate the possible prognostic significance of sICAM-1 concentration in colorectal cancer. METHODS:A total of 56 patients (mean age 57.3 years) having transitional cell c...

journal_title：World journal of gastroenterology

authors： Kang X,Wang F,Xie JD,Cao J,Xian PZ

更新日期：2005-07-21 00:00:00

abstract：:Over the past decade, research has shown that aberrant expression of microRNA (miRNA) is involved in colorectal cancer development and progression. MicroRNAs are small sequences of non-coding RNA that regulate expression of genes involved in important cellular functions, such as cell differentiation, multiplication, a...

journal_title：World journal of gastroenterology

authors： Hollis M,Nair K,Vyas A,Chaturvedi LS,Gambhir S,Vyas D

更新日期：2015-07-21 00:00:00

abstract：AIM:To investigate the influence of remote ischemic preconditioning (RIPC) on anastomotic integrity. METHODS:Sixty male Wistar rats were randomized to six groups. The control group (n = 10) had an end-to-end ileal anastomosis without RIPC. The preconditioned groups (n = 34) varied in time of ischemia and time of reper...

journal_title：World journal of gastroenterology

authors： Holzner PA,Kulemann B,Kuesters S,Timme S,Hoeppner J,Hopt UT,Marjanovic G

更新日期：2011-03-14 00:00:00

abstract：:Cytomegalovirus (CMV) infection is a common complication after liver transplantation, and it is associated with multiple direct and indirect effects. Management of CMV infection and disease has evolved over the years, and clinical guidelines have been recently updated. Universal antiviral prophylaxis and a pre-emptive...

journal_title：World journal of gastroenterology

authors： Marcelin JR,Beam E,Razonable RR

更新日期：2014-08-21 00:00:00

abstract：AIM:To assess the diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index (APRI), and liver stiffness measurement (LSM) in patients with hepatitis B virus infection who have persistently normal alanine transaminase (PNALT). METHODS:We enrolled 245 patients with chronic hepatitis B: 95 in PNALT gr...

journal_title：World journal of gastroenterology

authors： Tan YW,Zhou XB,Ye Y,He C,Ge GH

更新日期：2017-08-21 00:00:00

abstract：AIM:To investigate the effect of quercetin supplementation on the myenteric neurons and glia in the cecum of diabetic rats. METHODS:Total preparations of the muscular tunic were prepared from the ceca of twenty-four rats divided into the following groups: control (C), control supplemented with quercetin (200 mg/kg que...

journal_title：World journal of gastroenterology

authors： Ferreira PE,Lopes CR,Alves AM,Alves ÉP,Linden DR,Zanoni JN,Buttow NC

更新日期：2013-10-14 00:00:00

abstract：:We report a case of hepatocellular carcinoma (HCC) occurring in a patient with Crohn's disease (CD) without chronic hepatitis or liver cirrhosis, and review the clinicopathological features of HCC in CD patients. A 37-year-old Japanese man with an 8-year history of CD and a medication history of azathioprine underwent...

journal_title：World journal of gastroenterology

authors： Ishida M,Naka S,Shiomi H,Tsujikawa T,Andoh A,Nakahara T,Saito Y,Kurumi Y,Takikita-Suzuki M,Kojima F,Hotta M,Tani T,Fujiyama Y,Okabe H

更新日期：2010-07-07 00:00:00

abstract：:Primary rectal lymphoma is a rare presentation of gastrointestinal lymphomas. Its clinical presentation is indistinguishable from that of rectal carcinoma. Although surgical resection is often technically feasible, optimal therapy for colorectal lymphoma has not yet been identified. We report a case of primary rectal ...

journal_title：World journal of gastroenterology

authors： Bilsel Y,Balik E,Yamaner S,Bugra D

更新日期：2005-01-21 00:00:00

abstract：AIM:To clarify the expression and role of Ephrin receptor A4 (EphA4) in gastric cancer in relation to clinicopathological characteristics and the expression of fibroblast growth factor receptor 1 (FGFR1) and ephrin ligands. METHODS:Eleven gastric carcinoma cell lines, 24 paired surgical fresh specimens of gastric aden...

journal_title：World journal of gastroenterology

authors： Oki M,Yamamoto H,Taniguchi H,Adachi Y,Imai K,Shinomura Y

更新日期：2008-10-07 00:00:00

abstract：AIM:To compare the causes and clinical outcome of patients with acute upper gastrointestinal bleeding (AUGB) and a history of gastric surgery to those with AUGB but without a history of gastric surgery in the past. METHODS:The causes and clinical outcome were compared between 105 patients with AUGB and a history of ga...

journal_title：World journal of gastroenterology

authors： Nikolopoulou VN,Thomopoulos KC,Theocharis GI,Arvaniti VA,Vagianos CE

更新日期：2005-08-07 00:00:00

abstract：AIM:To make a retrospective analysis of endoscopy findings and clinicopathologic characteristics of colonic schistosomiasis in order to further improve our understanding of the disease and decrease its misdiagnosis. METHODS:Endoscopy findings and clinicopathologic characteristics of 46 intestinal schistosomiasis patie...

journal_title：World journal of gastroenterology

authors： Cao J,Liu WJ,Xu XY,Zou XP

更新日期：2010-02-14 00:00:00

abstract：AIM:To describe the significant over-expression of fibroblast growth factor receptor 3 (FGFR3), which is a signal transduction and cell proliferation related gene in hepatocellular carcinoma (HCC). METHODS:Following DNA microarray, Northern blot and quantitative real-time PCR were employed to confirm FGFR3 expression ...

journal_title：World journal of gastroenterology

authors： Qiu WH,Zhou BS,Chu PG,Chen WG,Chung C,Shih J,Hwu P,Yeh C,Lopez R,Yen Y

更新日期：2005-09-14 00:00:00

abstract：AIM:To validate the clinical Rockall score in predicting outcomes (rebleeding, surgery and mortality) in elderly patients with acute upper gastrointestinal bleeding (AUGIB). METHODS:A retrospective analysis was undertaken in 341 patients admitted to the emergency room and Intensive Care Unit of Xuanwu Hospital of Capi...

journal_title：World journal of gastroenterology

authors： Wang CY,Qin J,Wang J,Sun CY,Cao T,Zhu DD

更新日期：2013-06-14 00:00:00

abstract：AIM:To investigate the value of ultrasound elastography combined with serological indexes in diagnosing liver fibrosis and assessing its severity. METHODS:A total of 338 chronic hepatitis B (CHB) patients were divided into a disease group (patients with hepatic fibrosis) and control group (subjects without hepatic fib...

journal_title：World journal of gastroenterology

authors： Xu B,Zhou NM,Cao WT,Li XJ

更新日期：2018-10-07 00:00:00

abstract：AIM:To investigate usefulness of adherence to gastro-esophageal reflux disease (GERD) guideline established by the Spanish Association of Gastroenterology. METHODS:Prospective, observational and multicentre study of 301 patients with typical symptoms of GERD who should be managed in accordance with guidelines and were...

journal_title：World journal of gastroenterology

authors： Mearin F,Ponce J,Ponce M,Balboa A,González MA,Zapardiel J

更新日期：2012-09-21 00:00:00

abstract：:Helicobacter pylori (H. pylori) affects nearly half of the world's population and, thus, is one of the most frequent and persistent bacterial infections worldwide. H. pylori is associated with peptic ulcer disease, gastric ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer. Various diagnostic metho...

journal_title：World journal of gastroenterology

authors： Garza-González E,Perez-Perez GI,Maldonado-Garza HJ,Bosques-Padilla FJ

更新日期：2014-02-14 00:00:00

abstract：AIM:To determine whether bispectral index (BIS) monitoring is useful for propofol administration for deep sedation during endoscopic retrograde cholangiopancreatography (ERCP). METHODS:Fifty-nine consecutive patients with a variety of reasons for ERCP who underwent the procedure at least twice between 1 July 2010 and ...

journal_title：World journal of gastroenterology

authors： Jang SY,Park HG,Jung MK,Cho CM,Park SY,Jeon SW,Tak WY,Kweon YO,Kim SK,Jeon YH

更新日期：2012-11-21 00:00:00

abstract：:Mesenteric venous thrombosis (MVT) is a rare but life threatening form of bowel ischemia. It is implicated in 6%-9% of all cases of acute mesenteric ischemia. The proportion of patients with primary (or idiopathic) MVT varies from 0% to 49%, with a decrease in frequency secondary to more recent availability of newer i...

journal_title：World journal of gastroenterology

authors： Karmacharya P,Aryal MR,Donato A

更新日期：2013-11-21 00:00:00

abstract：:A primary clear cell adenocarcinoma of the colon is a rare oncologic entity. We herein report a case of such a tumor of the sigmoid colon in a 71-year-old woman who was successfully treated by an endoscopic polypectomy in our hospital. We also reviewed the published reports regarding cases of primary clear cell tumors...

journal_title：World journal of gastroenterology

authors： Soga K,Konishi H,Tatsumi N,Konishi C,Nakano K,Wakabayashi N,Mitsufuji S,Kataoka K,Okanoue T,Mukaisho K,Hattori T

更新日期：2008-02-21 00:00:00

abstract：:Pancreatic cancer is one of the deadliest cancers, ranking fourth among cancer-related deaths. Despite all the major molecular advances and treatment breakthroughs, mainly targeted therapies, the cornerstone treatment of metastatic pancreatic cancer (mPC) remains cytotoxic chemotherapy. In 2016, more than 40 years aft...

journal_title：World journal of gastroenterology

authors： Ghosn M,Ibrahim T,Assi T,El Rassy E,Kourie HR,Kattan J

更新日期：2016-12-14 00:00:00

abstract：AIM:To evaluate virological response to adefovir (ADV) monotherapy and emergence of ADV-resistant mutations in lamivudine (LAM)-resistant chronic hepatitis B patients. METHODS:Seventy-seven patients with documented LAM resistance who were treated with 10 mg/d ADV for > 96 wk were analyzed for ADV resistance. RESULTS:...

journal_title：World journal of gastroenterology

authors： Sinn DH,Lee HIe,Gwak GY,Choi MS,Koh KC,Paik SW,Yoo BC,Lee JH

更新日期：2011-08-14 00:00:00

abstract：BACKGROUND:Intestinal inflammation is a common digestive tract disease, which is usually treated with hormone medicines. Hormone medicines are effective to some extent, but long-term use of them may bring about many complications. AIM:To explore the protective effects of panax notoginseng saponin (PNS) against dextran...

journal_title：World journal of gastroenterology

authors： Lu QG,Zeng L,Li XH,Liu Y,Du XF,Bai GM,Yan X

更新日期：2020-03-21 00:00:00

abstract：AIM:To examine the expression of activin A, a member of the transforming growth factor (TGFbeta) superfamily, recently has been reported to be overexpressed in liver cirrhosis, in the course of carbon tetrachloride-induced rat hepatic fibrosis. METHODS:Hepatic fibrosis was induced in rats by subcutaneous injections of...

journal_title：World journal of gastroenterology

authors： Huang X,Li DG,Wang ZR,Wei HS,Cheng JL,Zhan YT,Zhou X,Xu QF,Li X,Lu HM

更新日期：2001-02-01 00:00:00

abstract：AIM:To elucidate the role and alterations of syndecan-1 and E-cadherin expression in different cellular phenotypes of differentiated-type gastric cancers (DGCs). METHODS:A total of 120 DGCs at an early stage, and their adjacent mucosa, were studied both by immunohistochemistry. Syndecan-1 and E-cadherin were assessed ...

journal_title：World journal of gastroenterology

authors： Huang MF,Zhu YQ,Chen ZF,Xiao J,Huang X,Xiong YY,Yang GF

更新日期：2005-05-21 00:00:00

abstract：:AIM:To explore the risk factors of gallbladder stone recurrence.METHODS:A multifactorial analysis was made for 1058 patients in Shanghai area whose gallbladder stones disappeared after different kinds of nonsurgical therapy,including oral litholytic therapy, extracorporeal shock wave lithotripsy and percutaneous chole...

journal_title：World journal of gastroenterology

authors： Chen P,Wang BS,He LQ

更新日期：1999-02-01 00:00:00

abstract：:Liver resection for hepatocellular carcinoma (HCC) is currently known to be a safer procedure than it was before because of technical advances and improvement in postoperative patient management and remains the first-line treatment for HCC in compensated cirrhosis. The aim of this review is to assess current indicatio...

journal_title：World journal of gastroenterology

authors： Gaillard M,Tranchart H,Dagher I

更新日期：2014-05-07 00:00:00