Omeprazole induces gastric transmucosal permeability to the peptide bradykinin.

abstract：:Treatment of Helicobacter pylori (H. pylori) infection is paramount for the management of prevalent gastrointestinal disorders including peptic ulcer disease and gastric cancer. Due to the wide increase in prevalence of H. pylori resistance to antibiotics, clarithromycin-based triple therapies are not any more suitabl...

journal_title：World journal of gastroenterology

authors： Papastergiou V,Georgopoulos SD,Karatapanis S

更新日期：2014-08-07 00:00:00

abstract：AIM:To clarify the association of glypican-3 (GPC3) expression with Wnt and other growth signaling molecules in hepatocellular carcinoma (HCC). METHODS:Expression of GPC3, Wnt, matrix metalloproteinases (MMPs), sulfatase (SULF)1, SULF2, and other growth signaling molecules was analyzed in HCC cell lines and tissue sam...

journal_title：World journal of gastroenterology

authors： Akutsu N,Yamamoto H,Sasaki S,Taniguchi H,Arimura Y,Imai K,Shinomura Y

更新日期：2010-07-28 00:00:00

abstract：:Ulcerative colitis (UC) is an inflammatory destructive disease of the large intestine occurred usually in the rectum and lower part of the colon as well as the entire colon. Drug therapy is not the only choice for UC treatment and medical management should be as a comprehensive whole. Azulfidine, Asacol, Pentasa, Dipe...

journal_title：World journal of gastroenterology

authors： Xu CT,Meng SY,Pan BR

更新日期：2004-08-15 00:00:00

abstract：AIM:To make a retrospective analysis of endoscopy findings and clinicopathologic characteristics of colonic schistosomiasis in order to further improve our understanding of the disease and decrease its misdiagnosis. METHODS:Endoscopy findings and clinicopathologic characteristics of 46 intestinal schistosomiasis patie...

journal_title：World journal of gastroenterology

authors： Cao J,Liu WJ,Xu XY,Zou XP

更新日期：2010-02-14 00:00:00

abstract：AIM:To investigate the ultrastructure of oval cells in children with chronic hepatitis B, with special emphasis on their location in areas of collagen fibroplasia. METHODS:Morphological investigations were conducted on biopsy material obtained from 40 children, aged 3-16 years with chronic hepatitis B. The stage of fi...

journal_title：World journal of gastroenterology

authors： Sobaniec-Lotowska ME,Lotowska JM,Lebensztejn DM

更新日期：2007-06-07 00:00:00

abstract：AIM:To determine the prevalences of symptoms consistent with gastroesophageal reflux disease (GERD) and dyspepsia in South America. METHODS:A telephone survey was conducted among adult owners of land-based telephones in São Paulo, Brazil, using previously validated computer-assisted sampling and survey protocols. The ...

journal_title：World journal of gastroenterology

authors： do Rosário Dias de Oliveira Latorre M,Medeiros da Silva A,Chinzon D,Eisig JN,Dias-Bastos TR

更新日期：2014-12-14 00:00:00

abstract：:According to the main international clinical guidelines, the recommended treatment for locally-advanced rectal cancer is neoadjuvant chemoradiotherapy followed by surgery. However, doubts have been raised about the appropriate definition of clinical complete response (cCR) after neoadjuvant therapy and the role of sur...

journal_title：World journal of gastroenterology

authors： López-Campos F,Martín-Martín M,Fornell-Pérez R,García-Pérez JC,Die-Trill J,Fuentes-Mateos R,López-Durán S,Domínguez-Rullán J,Ferreiro R,Riquelme-Oliveira A,Hervás-Morón A,Couñago F

更新日期：2020-08-07 00:00:00

abstract：AIM:To investigate the roles of Fas signaling pathway in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells. METHODS:Human gastric cancer SGC-7901 cells were treated with VES at 5, 10, 20 mg x L(-1), succinic acid and vitamin E as vehicle control and condition media only as untreated (UT) con...

journal_title：World journal of gastroenterology

authors： Wu K,Li Y,Zhao Y,Shan YJ,Xia W,Yu WP,Zhao L

更新日期：2002-12-01 00:00:00

abstract：AIM:To investigate whether ANNs and LDA could recognize patients with ABG in a database, containing only clinical and biochemical variables, of a pool of patients with and without ABG, by selecting the most predictive variables and by reducing input data to the minimum. METHODS:Data was collected from 350 consecutive ...

journal_title：World journal of gastroenterology

authors： Lahner E,Grossi E,Intraligi M,Buscema M,Corleto VD,Delle Fave G,Annibale B

更新日期：2005-10-07 00:00:00

abstract：AIM:To investigate the pharmacological effects of rice flavone (5,4'-dihydroxy-3',5'-dimethoxy-7-O-beta-D-glucopyranosyloxy-flavone, RF) separated from panicle-differentiating to flowing rice on rat experimental hepatic injury. METHODS:Models of rat acute hepatic injury induced by carbon tetrachloride (CCl(4)) adminis...

journal_title：World journal of gastroenterology

authors： Xu DH,Mei XT,Chen Y,Li YM,Lv JY,Xu SB

更新日期：2005-03-28 00:00:00

abstract：:Duodenal polyps or lesions are uncommonly found on upper endoscopy. Duodenal lesions can be categorized as subepithelial or mucosally-based, and the type of lesion often dictates the work-up and possible therapeutic options. Subepithelial lesions that can arise in the duodenum include lipomas, gastrointestinal stromal...

journal_title：World journal of gastroenterology

authors： Gaspar JP,Stelow EB,Wang AY

更新日期：2016-01-14 00:00:00

abstract：AIM:To investigate the inhibitory effect and possible mechanism of action of schisandrin B in SC-B on gastric cancer cells in vitro. METHODS:SC-B consisted of schisandrin B, aloe-emodin, and Astragalus polysaccharides. Exponentially growing human gastric cancer SGC-7901 cells were divided into six treatment groups: (1...

journal_title：World journal of gastroenterology

authors： Liu XN,Zhang CY,Jin XD,Li YZ,Zheng XZ,Li L

更新日期：2007-12-28 00:00:00

abstract：AIM:To validate the clinical Rockall score in predicting outcomes (rebleeding, surgery and mortality) in elderly patients with acute upper gastrointestinal bleeding (AUGIB). METHODS:A retrospective analysis was undertaken in 341 patients admitted to the emergency room and Intensive Care Unit of Xuanwu Hospital of Capi...

journal_title：World journal of gastroenterology

authors： Wang CY,Qin J,Wang J,Sun CY,Cao T,Zhu DD

更新日期：2013-06-14 00:00:00

abstract：:Increased numbers of mucosa-associated Escherichia coli are observed in both of the major inflammatory bowel diseases, Crohn d' disease (CD) and ulcerative colitis (UC). A potential pathophysiological link between the presence of pathogenic invasive bacteria and genetic host susceptibility of patients with ileal CD is...

journal_title：World journal of gastroenterology

authors： Barnich N,Darfeuille-Michaud A

更新日期：2007-11-14 00:00:00

abstract：:We report a case of intraductal papillary neoplasm of the bile duct (IPNB) that developed in a patient with primary sclerosing cholangitis. A 46-year-old woman was admitted to our hospital with obstructive jaundice. The liver function tests demonstrated increased serum liver enzyme levels. Computed tomography showed d...

journal_title：World journal of gastroenterology

authors： Hachiya H,Kita J,Shiraki T,Iso Y,Shimoda M,Kubota K

更新日期：2014-11-14 00:00:00

abstract：AIM:To investigate the ability of histamine to modulate tryptase release from human colon mast cells and the potential mechanisms. METHODS:Enzymatically dispersed cells from human colons were challenged with histamine, anti-IgE or calcium ionophore A23187 (CI), and the cell supernatants after challenge were collected....

journal_title：World journal of gastroenterology

authors： He SH,Xie H

更新日期：2004-02-01 00:00:00

abstract：AIM:To counteract/reveal celecoxib-induced toxicity and NO system involvement. METHODS:Celecoxib (1 g/kg b.w. ip) was combined with therapy with stable gastric pentadecapeptide BPC 157 (known to inhibit these lesions, 10 μg/kg, 10 ng/kg, or 1 ng/kg ip) and L-arginine (100 mg/kg ip), as well as NOS blockade [N(G)-nitro...

journal_title：World journal of gastroenterology

authors： Drmic D,Kolenc D,Ilic S,Bauk L,Sever M,Zenko Sever A,Luetic K,Suran J,Seiwerth S,Sikiric P

更新日期：2017-08-07 00:00:00

abstract：AIM:To explore recent trends, modes of diagnosis, ethnic distribution and the mortality to incidence ratio of primary liver cancer by subtypes in England and Wales. METHODS:We obtained incidence (1979-2008) and mortality (1968-2008) data for primary liver cancer for England and Wales and calculated age-standardised in...

journal_title：World journal of gastroenterology

authors： Ladep NG,Khan SA,Crossey MM,Thillainayagam AV,Taylor-Robinson SD,Toledano MB

更新日期：2014-02-14 00:00:00

abstract：AIM:To find out whether a newly designed big cup nitinol stent is suitable for treatment of patients with gastric outlet obstruction resulting from gastric cancer. METHODS:The new stent is composed of a proximal big cup segment (20 mm in length and 48-55 mm in diameter), a middle part (60 mm in length and 20 mm in dia...

journal_title：World journal of gastroenterology

authors： Shi D,Liao SH,Geng JP

更新日期：2010-09-07 00:00:00

abstract：:Colorectal cancer (CRC) is the third most common cancer worldwide and, despite improved treatments, is still an important cause of cancer-related deaths. CRC encompasses a complex of diseases arising from a multi-step process of genetic and epigenetic events. Besides heterogeneity in the molecular and biological featu...

journal_title：World journal of gastroenterology

authors： Bertorelle R,Rampazzo E,Pucciarelli S,Nitti D,De Rossi A

更新日期：2014-02-28 00:00:00

abstract：:A 36-year-old male Asian immigrant with a history of hepatitis B and hepatitis C related unresectable hepatocellular carcinoma in the left lobe of the liver presented with hematemesis and severe anemia. He was diagnosed with a liver mass that was resected 8 years ago described as a benign tumor in his home country. He...

journal_title：World journal of gastroenterology

authors： Sayana H,Yousef O,Clarkston WK

更新日期：2013-11-14 00:00:00

abstract：AIM:To investigate the prevalence of gastroesophageal reflux disease (GERD) in patients with a laryngoscopic diagnosis of laryngopharyngeal reflux (LPR). METHODS:Between May 2011 and October 2011, 41 consecutive patients with laryngopharyngeal symptoms (LPS) and laryngoscopic diagnosis of LPR were empirically treated ...

journal_title：World journal of gastroenterology

authors： de Bortoli N,Nacci A,Savarino E,Martinucci I,Bellini M,Fattori B,Ceccarelli L,Costa F,Mumolo MG,Ricchiuti A,Savarino V,Berrettini S,Marchi S

更新日期：2012-08-28 00:00:00

abstract：AIM:To evaluate the efficacy of furazolidone-based triple and quadruple therapy in eradicating Helicobacter pylori (H. pylori) in a multi-center randomized controlled trial. METHODS:A total of 720 H. pylori positive patients with duodenal ulcer disease were enrolled at 10 different hospitals in Jiangxi province in Chi...

journal_title：World journal of gastroenterology

authors： Xie Y,Zhu Y,Zhou H,Lu ZF,Yang Z,Shu X,Guo XB,Fan HZ,Tang JH,Zeng XP,Wen JB,Li XQ,He XX,Ma JH,Liu DS,Huang CB,Xu NJ,Wang NR,Lu NH

更新日期：2014-08-28 00:00:00

abstract：:Autoimmune hepatitis (AIH) is a rare chronic inflammatory disease of the liver, which affects a group of patients who lost their immunological tolerance to antigens of the liver. It is clinically characterized by hypergammaglobulinemia, elevated liver enzymes, presence of autoantibodies and histological changes. Altho...

journal_title：World journal of gastroenterology

authors： Ferri Liu PM,de Miranda DM,Fagundes ED,Ferreira AR,Simões e Silva AC

更新日期：2013-07-28 00:00:00

abstract：AIM:To assess whether the use of fibrin sealant shortens the closure time of postoperative enterocutaneous fistulas (ECFs). METHODS:The prospective case-control study included 70 patients with postoperative ECFs with an output of < 500 mL/d, a fistulous tract of > 2 cm and without any local complication. They were div...

journal_title：World journal of gastroenterology

authors： Avalos-González J,Portilla-deBuen E,Leal-Cortés CA,Orozco-Mosqueda A,Estrada-Aguilar Mdel C,Velázquez-Ramírez GA,Ambriz-González G,Fuentes-Orozco C,Guzmán-Gurrola AE,González-Ojeda A

更新日期：2010-06-14 00:00:00

abstract：AIM:To compare the number of regulatory T-cells (Tregs) measured by flow cytometry with those obtained using a real-time quantitative PCR (qPCR) method in patients suffering from inflammatory bowel disease (IBD). METHODS:Tregs percentages obtained by both flow cytometry and qPCR methods in 35 adult IBD patients, 18 ou...

journal_title：World journal of gastroenterology

authors： Brandhorst G,Petrova DT,Weigand S,Eberle C,von Ahsen N,Schmitz J,Schultze FC,Raddatz D,Karaus M,Oellerich M,Walson PD

更新日期：2015-03-21 00:00:00

abstract：:A number of alterations have been found within the gut microbial profile of patients with inflammatory bowel diseases when compared with the healthy population; however, it is unclear whether such dysbiosis is the cause or simply the consequence of the disease state. In ulcerative colitis, the environment seems to pla...

journal_title：World journal of gastroenterology

authors： Sorrentino D

更新日期：2017-10-07 00:00:00

abstract：AIM:To elucidate cell proliferation in erosive reflux disease (ERD) and non-erosive reflux disease (NERD), we evaluated markers in squamous epithelial cells. METHODS:Thirty-four consecutive patients with gastroesophageal-reflux-disease-related symptoms (21 NERD and 13 ERD) were evaluated for the enrolment into the stu...

journal_title：World journal of gastroenterology

authors： Calabrese C,Montanaro L,Liguori G,Brighenti E,Vici M,Gionchetti P,Rizzello F,Campieri M,Derenzini M,Trerè D

更新日期：2011-10-28 00:00:00

abstract：AIM:To evaluate the feasibility and utility of confocal laser endomicroscopy (CLE) in the description of normal gastrointestinal (GI) mucosa and in the diagnosis of GI disorders in children, in comparison to histology. METHODS:Forty-four patients (19 female) median age 10.9 years (range 0.7-16.6 years) with suspected ...

journal_title：World journal of gastroenterology

authors： Venkatesh K,Cohen M,Evans C,Delaney P,Thomas S,Taylor C,Abou-Taleb A,Kiesslich R,Thomson M

更新日期：2009-05-14 00:00:00

abstract：AIM:To investigate the role of reactive oxygen species (ROS) in ethanol-mediated cell death of polarized hepatic (WIF-B) cells. METHODS:In this work, WIF-B cultures were treated with pyrazole (inducer of cytochrome P4502E1, CYP2E1) and/or L-buthionine sulfoximine (BSO), a known inhibitor of hepatic glutathione (GSH), ...

journal_title：World journal of gastroenterology

authors： McVicker BL,Tuma PL,Kharbanda KK,Lee SM,Tuma DJ

更新日期：2009-06-07 00:00:00