Intraductal papillary neoplasm of the bile duct developing in a patient with primary sclerosing cholangitis: a case report.

abstract：:Alcoholic liver disease (ALD) is characterized by steatosis or fat deposition in the liver and inflammation, which leads to cirrhosis and hepatocellular carcinoma. Induction of target genes without involving changes in DNA sequence seems to contribute greatly to liver injury. Chromatin modifications including alterati...

journal_title：World journal of gastroenterology

authors： Mandrekar P

更新日期：2011-05-28 00:00:00

abstract：AIM:To investigate the clinical implications of hepatitis B virus (HBV) preS1 deletion. METHODS:We developed a fluorescence resonance energy transfer-based real-time polymerase chain reaction (RT-PCR) that can detect four genotypes (wild type, 15-bp, 18-bp and 21-bp deletion). The PCR method was used in two cohorts of...

journal_title：World journal of gastroenterology

authors： Lee SA,Kim KJ,Kim H,Choi WH,Won YS,Kim BJ

更新日期：2015-04-28 00:00:00

abstract：AIM:To investigate the clinical efficacy and toxic effects of neoadjuvant chemotherapy using docetaxel combined with oxaliplatin and fluorouracil for treating stage III/IV gastric cancer. METHODS:A total of 53 stage III/IV gastric cancer patients were enrolled into the study and treated with neoadjuvant chemotherapy. ...

journal_title：World journal of gastroenterology

authors： Yu YJ,Sun WJ,Lu MD,Wang FH,Qi DS,Zhang Y,Li PH,Huang H,You T,Zheng ZQ

更新日期：2014-12-28 00:00:00

abstract：AIM:To observe the effect of protocatechuic aldchyde on the proliferation of hepatic stellate cells (HSCs). METHODS:Liver fibrosis was induced in rats by carbon tetrachloride (CCl4). Then normal and fibrotic drug sera were extracted from rats. The effects of protocatechuic aldchyde, raw Radix Salvia miltiorrhiza and d...

journal_title：World journal of gastroenterology

authors： Lv T,Yao XX

更新日期：2006-04-14 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most frequent tumors worldwide. The majority of HCC cases occur in patients with chronic liver disease. Despite regular surveillance to detect small HCC in these patients, HCC is often diagnosed at an advanced stage. Because HCC is highly resistant to conventional systemic ...

journal_title：World journal of gastroenterology

authors： Shin JW,Chung YH

更新日期：2013-10-07 00:00:00

abstract：AIM:To assess the diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index (APRI), and liver stiffness measurement (LSM) in patients with hepatitis B virus infection who have persistently normal alanine transaminase (PNALT). METHODS:We enrolled 245 patients with chronic hepatitis B: 95 in PNALT gr...

journal_title：World journal of gastroenterology

authors： Tan YW,Zhou XB,Ye Y,He C,Ge GH

更新日期：2017-08-21 00:00:00

abstract：AIM:To determine whether any changes have occurred on the patterns of colorectal cancer in China. METHODS:Data from 21 Chinese articles published from 1980 to 1999, were used to analyze the time trend of colorectal cancer according to the patients' age at diagnosis, sex, the site of the tumor, stage, and the pathology...

journal_title：World journal of gastroenterology

authors： Li M,Gu J

更新日期：2005-08-14 00:00:00

abstract：:A 65-year-old man with cT1bN0M0 stage I middle thoracic esophageal cancer underwent subtotal esophagectomy and gastric tube reconstruction through the posterior mediastinal route after preoperative carbon-ion radiotherapy and chemotherapy in a clinical trial. Anastomotic leakage occurred, but it spontaneously improved...

journal_title：World journal of gastroenterology

authors： Uesato M,Kono T,Akutsu Y,Murakami K,Kagaya A,Muto Y,Nakano A,Aikawa M,Tamachi T,Amagai H,Arasawa T,Muto Y,Matsubara H

更新日期：2017-07-28 00:00:00

abstract：:Despite substantial efforts at early diagnosis, accurate staging and advanced treatments, esophageal cancer (EC) continues to be an ominous disease worldwide. Risk factors for esophageal carcinomas include obesity, gastroesophageal reflux disease, hard-alcohol use and tobacco smoking. Five-year survival rates have imp...

journal_title：World journal of gastroenterology

authors： DaVee T,Ajani JA,Lee JH

更新日期：2017-02-07 00:00:00

abstract：:Despite the recent advances in the therapeutic modalities, colorectal cancer (CRC) remains to be one of the most common causes of cancer-related death. CRC arises through accumulation of multiple genetic and epigenetic alterations that transform normal colonic epithelium into adenocarcinomas. Among crucial roles of ep...

journal_title：World journal of gastroenterology

authors： Sakai E,Nakajima A,Kaneda A

更新日期：2014-01-28 00:00:00

abstract：AIM:To elucidate the effect of angiogenesis inhibitor, Linomide, on tumor growth and metastasis in nude mice implanted with human gastric cancer. METHODS:A metastatic model of gastric cancer was established using orthotopic implantation of histologically intact tumor tissues into the gastric wall of nude mice. Linomid...

journal_title：World journal of gastroenterology

authors： Tao HQ,Lin YZ,Yin HR,Gu QL,Zhu ZG,Yao M

更新日期：1997-09-15 00:00:00

abstract：:Surgery represents the main curative therapeutic modality for gastric cancer, and it is occasionally considered for palliation as well as prophylaxis. Most frequently, surgical outcomes are conveyed in terms of oncological outcomes such as recurrence and survival. However, quality of life (QoL) is also important and s...

journal_title：World journal of gastroenterology

authors： McCall MD,Graham PJ,Bathe OF

更新日期：2016-01-21 00:00:00

abstract：:Chronic radiation proctopathy occurs in 5%-20% of patients following pelvic radiotherapy. Although many cases resolve spontaneously, some lead to chronic symptoms including diarrhea, tenesmus, urgency and persistent rectal bleeding with iron deficiency anemia requiring blood transfusions. Treatments for chronic radiat...

journal_title：World journal of gastroenterology

authors： Rustagi T,Mashimo H

更新日期：2011-11-07 00:00:00

abstract：AIM:To construct a DNA vaccine against extracellular domains 1-3 of fetal liver kinase-1 (flk-1), and to investigate its preventive and therapeutic effect against H22 cell in vivo. METHODS:Flk-1 DNA vaccine was produced by cloning extracellular domains 1-3 of flk-1 and by inserting the cloned gene into pcDNA3.1 (+). F...

journal_title：World journal of gastroenterology

authors： Lü F,Qin ZY,Yang WB,Qi YX,Li YM

更新日期：2004-07-15 00:00:00

abstract：AIM:To evaluate the functional aspect of esophageal motility in healthy subjects and in patients who were referred for esophageal function testing using multichannel intraluminal impedance-esophageal manometry (MII-EM), and to assess the clinical utility of MII-EM. METHODS:From September 2003 to January 2004, we perfo...

journal_title：World journal of gastroenterology

authors： Cho YK,Choi MG,Park JM,Oh JH,Paik CN,Lee JW,Lee IS,Kim SW,Chung IS

更新日期：2006-10-21 00:00:00

abstract：AIM:To find risk factors of lymph node metastasis (LNM) in early gastric cancer (EGC) and to find proper endoscopic therapy indication in EGC. METHODS:We retrospectively reviewed the 2270 patients who underwent curative operation for EGC from January 2001 to December 2008. EGC was defined as malignant lesions that do ...

journal_title：World journal of gastroenterology

authors： Park JH,Lee SH,Park JM,Park CS,Park KS,Kim ES,Cho KB

更新日期：2015-10-21 00:00:00

abstract：AIM:To investigate the anti-hepatofibrotic effects of Gardenia jasminoides in liver fibrosis. METHODS:Male Sprague-Dawley rats underwent common bile duct ligation (BDL) for 14 d and were treated with Gardenia jasminoides by gavage. The effects of Gardenia jasminoides on liver fibrosis and the detailed molecular mechan...

journal_title：World journal of gastroenterology

authors： Chen YH,Lan T,Li J,Qiu CH,Wu T,Gou HJ,Lu MQ

更新日期：2012-12-28 00:00:00

abstract：:Although primary gastrointestinal lymphoma is a rare malignancy, it can cause an intussusception in adults and can be a clinically challenging condition to manage. Intussusception could progress to life-threatening complications if left untreated or could delay chemotherapy if inappropriate surgical management is used...

journal_title：World journal of gastroenterology

authors： Yang TW,Lin YY,Tsuei YW,Chen YL,Huang CY,Hsu SD

更新日期：2016-05-21 00:00:00

abstract：:The etiology of inflammatory bowel disease (IBD) has not yet been clarified and immunosuppressive agents which non-specifically reduce inflammation and immunity have been used in the conventional therapies for IBD. Evidence indicates that a dysregulation of mucosal immunity in the gut of IBD causes an overproduction o...

journal_title：World journal of gastroenterology

authors： Nakamura K,Honda K,Mizutani T,Akiho H,Harada N

更新日期：2006-08-07 00:00:00

abstract：AIM:To test the effect of the dephytinization of three different commercial infant cereals on iron, calcium, and zinc bioavailability by estimating the uptake, retention, and transport by Caco-2 cells. METHODS:Both dephytinized (by adding an exogenous phytase) and non-dephytinized infant cereals were digested using an...

journal_title：World journal of gastroenterology

authors： Frontela C,Scarino ML,Ferruzza S,Ros G,Martínez C

更新日期：2009-04-28 00:00:00

abstract：:Foreign body ingestion is a common complaint in gastrointestinal clinics. It is usually not difficult to diagnose because most of the patients report a definitive history of accidental foreign body ingestion. However, in rare cases, patients do not have a clear history. Thus, the actual condition of the patient is dif...

journal_title：World journal of gastroenterology

authors： Lu YP,Yao M,Zhou XY,Huang B,Qi WB,Chen ZH,Xu LS

更新日期：2014-10-21 00:00:00

abstract：AIM:To describe a method for the transjugular intrahepatic portal systemic shunt (TIPS) placement performed with the aid of contrast-enhanced computed tomography (CECT) and three-dimensional reconstructed vascular images (3D RVIs), and to assess its safety and effectiveness. METHODS:Four hundred and ninety patients we...

journal_title：World journal of gastroenterology

authors： Qin JP,Tang SH,Jiang MD,He QW,Chen HB,Yao X,Zeng WZ,Gu M

更新日期：2015-08-28 00:00:00

abstract：AIM:To investigate mutation of serine protease 1-cationic trypsinogen (CT, PRSS1) gene in members of a Thai family with hereditary pancreatitis and pancreatic cancer. METHODS:Polymerase chain reaction and direct sequencing were performed to analyze the PRSS1 gene in two members of the family affected by pancreatitis. ...

journal_title：World journal of gastroenterology

authors： Pho-Iam T,Thongnoppakhun W,Yenchitsomanus PT,Limwongse C

更新日期：2005-03-21 00:00:00

abstract：:Biodegradable stents (BDSs) are an attractive option to avoid ongoing dilation or surgery in patients with benign stenoses of the small and large intestines. The experience with the currently the only BDS for endoscopic placement, made of Poly-dioxanone, have shown promising results. However some aspects should be imp...

journal_title：World journal of gastroenterology

authors： Lorenzo-Zúñiga V,Moreno-de-Vega V,Marín I,Boix J

更新日期：2014-03-07 00:00:00

abstract：:Occult hepatitis B virus (HBV) infection (OBI), alternatively defined as occult hepatitis B (OHB), is a challenging clinical entity. It is recognized by two main characteristics: absence of HBsAg, and low viral replication. The previous two decades have witnessed a remarkable progress in our understanding of OBI and i...

journal_title：World journal of gastroenterology

authors： Said ZN

更新日期：2011-04-21 00:00:00

abstract：AIM:To meta-analyse the European abstracts presented between 1997-2004 at the European H pylori Study Group, United European Gastroenterology Week meetings and World Congresses of Gastroenterology. METHODS:The abstracts of randomized/controlled prospective studies were classified into groups based on first-line eradic...

journal_title：World journal of gastroenterology

authors： Buzás GM,Józan J

更新日期：2006-09-07 00:00:00

abstract：:Video capsule endoscopy (CE) since its introduction 13 years back, has revolutionized our approach to small intestinal diseases. Obscure gastrointestinal bleed (OGIB) continues to be the most important indication for CE with a high sensitivity, specificity as well as positive and negative predictive values. It is best...

journal_title：World journal of gastroenterology

authors： Goenka MK,Majumder S,Goenka U

更新日期：2014-08-07 00:00:00

abstract：AIM:To describe the imaging features of solitary fibrous tumors (SFTs) in the abdomen and pelvis, and the clinical and pathologic correlations. METHODS:Fifteen patients with pathologically confirmed SFTs in the abdomen and pelvis were retrospectively studied with imaging techniques by two radiologists in consensus. Pa...

journal_title：World journal of gastroenterology

authors： Li XM,Reng J,Zhou P,Cao Y,Cheng ZZ,Xiao Y,Xu GH

更新日期：2014-05-07 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection is the most common cause of hepatic fibrosis and hepatocellular carcinoma (HCC), mainly as a result of chronic necroinflammatory liver disease. A characteristic feature of chronic hepatitis B infection, alcoholic liver disease and nonalcoholic fatty liver disease (NAFLD) is he...

journal_title：World journal of gastroenterology

authors： Shimizu I,Kohno N,Tamaki K,Shono M,Huang HW,He JH,Yao DF

更新日期：2007-08-28 00:00:00

abstract：:Ulcerative colitis (UC) is a chronic disease characterized by diffuse inflammation of the mucosa of the colon and rectum. The hallmark clinical symptom of UC is bloody diarrhea. The clinical course is marked by exacerbations and remissions, which may occur spontaneously or in response to treatment changes or intercurr...

journal_title：World journal of gastroenterology

authors： da Silva BC,Lyra AC,Rocha R,Santana GO

更新日期：2014-07-28 00:00:00