Epidemiology, demographic characteristics and prognostic predictors of ulcerative colitis.

Abstract:

:Ulcerative colitis (UC) is a chronic disease characterized by diffuse inflammation of the mucosa of the colon and rectum. The hallmark clinical symptom of UC is bloody diarrhea. The clinical course is marked by exacerbations and remissions, which may occur spontaneously or in response to treatment changes or intercurrent illnesses. UC is most commonly diagnosed in late adolescence or early adulthood, but it can occur at any age. The incidence of UC has increased worldwide over recent decades, especially in developing nations. In contrast, during this period, therapeutic advances have improved the life expectancy of patients, and there has been a decrease in the mortality rate over time. It is important to emphasize that there is considerable variability in the phenotypic presentation of UC. Within this context, certain clinical and demographic characteristics are useful in identifying patients who tend to have more severe evolution of the disease and a poor prognosis. In this group of patients, better clinical surveillance and more intensive therapy may change the natural course of the disease. The aim of this article was to review the epidemiology and demographic characteristics of UC and the factors that may be associated with its clinical prognosis.

journal_name

World J Gastroenterol

authors

da Silva BC,Lyra AC,Rocha R,Santana GO

doi

10.3748/wjg.v20.i28.9458

subject

Has Abstract

pub_date

2014-07-28 00:00:00

pages

9458-67

issue

28

eissn

1007-9327

issn

2219-2840

journal_volume

20

pub_type

杂志文章,评审
  • Pseudo-Meigs' syndrome secondary to metachronous ovarian metastases from transverse colon cancer.

    abstract::Pseudo-Meigs' syndrome associated with colorectal cancer is extremely rare. We report here a case of pseudo-Meigs' syndrome secondary to metachronous ovarian metastases from colon cancer. A 65-year-old female with a history of surgery for transverse colon cancer and peritoneal dissemination suffered from metachronous ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i18.4604

    authors: Kyo K,Maema A,Shirakawa M,Nakamura T,Koda K,Yokoyama H

    更新日期:2016-05-14 00:00:00

  • Construction and characterization of chimeric BHIV (BIV/HIV-1) viruses carrying the bovine immunodeficiency virus gag gene.

    abstract:AIM:To explore the possibility of the replacement of the gag gene between human immunodeficiency virus and bovine immunodeficiency virus, to achieve chimeric virions, and thereby gain a new kind of AIDS vaccine based on BHIV chimeric viruses. METHODS:A series of chimeric BHIV proviral DNAs differing in the replacement...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i17.2609

    authors: Zhu YX,Liu C,Liu XL,Qiao WT,Chen QM,Zeng Y,Geng YQ

    更新日期:2005-05-07 00:00:00

  • Gardenia jasminoides attenuates hepatocellular injury and fibrosis in bile duct-ligated rats and human hepatic stellate cells.

    abstract:AIM:To investigate the anti-hepatofibrotic effects of Gardenia jasminoides in liver fibrosis. METHODS:Male Sprague-Dawley rats underwent common bile duct ligation (BDL) for 14 d and were treated with Gardenia jasminoides by gavage. The effects of Gardenia jasminoides on liver fibrosis and the detailed molecular mechan...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i48.7158

    authors: Chen YH,Lan T,Li J,Qiu CH,Wu T,Gou HJ,Lu MQ

    更新日期:2012-12-28 00:00:00

  • New technologies in gastrointestinal research.

    abstract::This issue presents different new techniques aiming to increase our understanding of the gastrointestinal system and to improve treatment. The technologies cover selected methods to evoke and assess gut pain, new methods for imaging and physiological measurements, histochemistry, pharmacological modelling etc. There i...

    journal_title:World journal of gastroenterology

    pub_type: 社论

    doi:10.3748/wjg.15.129

    authors: Drewes AM,Gregersen H

    更新日期:2009-01-14 00:00:00

  • Living-related liver transplantation for multiple liver metastases from rectal carcinoid tumor: a case report.

    abstract::A 42-year-old woman was admitted to our hospital because of multiple liver tumors detected by ultrasonography. Colonoscopy revealed submucosal tumor in the rectum, which was considered the primary lesion. Endoscopic mucosal resection followed by histopathological examination revealed that the tumor was carcinoid. The ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i11.1805

    authors: Nakajima Y,Takagi H,Sohara N,Sato K,Kakizaki S,Nomoto K,Suzuki H,Suehiro T,Shimura T,Asao T,Kuwano H,Mori M,Nishikura K

    更新日期:2006-03-21 00:00:00

  • Associations between NOD2/CARD15 genotype and phenotype in Crohn's disease--Are we there yet?

    abstract::There have been multiple NOD2/CARD15 genotype-phenotype analyses undertaken in patients with Crohn's disease since the gene's discovery in 2001. This review focuses on the major published series based upon their size and on the presence of specific clinical and genetic information provided in the published material fr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审

    doi:10.3748/wjg.v12.i44.7097

    authors: Radford-Smith G,Pandeya N

    更新日期:2006-11-28 00:00:00

  • Diagnosis and treatment of benign multicystic peritoneal mesothelioma.

    abstract::Benign multicystic peritoneal mesothelioma (BMPM) is a rare cystic mesothelial lesion that occurs predominantly in reproductive aged women. A 56-year-old Caucasian male was admitted to our surgical department with a chief complaint of a painful mass in his right lower abdomen for almost 2 years. The physical examinati...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i39.6689

    authors: Wang TB,Dai WG,Liu DW,Shi HP,Dong WG

    更新日期:2013-10-21 00:00:00

  • Gastrointestinal perforation in metastatic colorectal cancer patients with peritoneal metastases receiving bevacizumab.

    abstract:AIM:To investigate the safety and efficacy of adding bevacizumab to first-line chemotherapy in metastatic colorectal cancer patients with peritoneal disease. METHODS:We compared rates of gastrointestinal perforation in patients with metastatic colorectal cancer and peritoneal disease receiving first-line chemotherapy ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i17.5352

    authors: Roohullah A,Wong HL,Sjoquist KM,Gibbs P,Field K,Tran B,Shapiro J,Mckendrick J,Yip D,Nott L,Gebski V,Ng W,Chua W,Price T,Tebbutt N,Chantrill L

    更新日期:2015-05-07 00:00:00

  • Transient elastography improves detection of liver cirrhosis compared to routine screening tests.

    abstract:AIM:To investigate the diagnostic significance of transient elastography (TE) in a daily routine clinical setting in comparison to clinical signs, laboratory parameters and ultrasound. METHODS:TE, ultrasound, laboratory parameters and cutaneous liver signs were assessed in 291 consecutive patients with chronic liver d...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i3.953

    authors: Göbel T,Schadewaldt-Tümmers J,Greiner L,Poremba C,Häussinger D,Erhardt A

    更新日期:2015-01-21 00:00:00

  • Laparoscopic liver resection: wedge resections to living donor hepatectomy, are we heading in the right direction?

    abstract::Despite inception over 15 years ago and over 3000 completed procedures, laparoscopic liver resection has remained mainly in the domain of selected centers and enthusiasts. Requirement of extensive open liver resection (OLR) experience, in-depth understanding of anatomy and considerable laparoscopic technical expertise...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i37.13369

    authors: Cherian PT,Mishra AK,Kumar P,Sachan VK,Bharathan A,Srikanth G,Senadhipan B,Rela MS

    更新日期:2014-10-07 00:00:00

  • ARC syndrome with high GGT cholestasis caused by VPS33B mutations.

    abstract::Arthrogryposis, renal dysfunction and cholestasis (ARC) syndrome (OMIM 208085) is an autosomal recessive disorder that is caused by mutations in 2 interacting genes VPS33B and VIPAS39. Mutations in VPS33B gene account for most cases of ARC. As low or normal gamma-glutamyl transpeptidase (GGT) activity has been describ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i16.4830

    authors: Wang JS,Zhao J,Li LT

    更新日期:2014-04-28 00:00:00

  • Autoantibodies against MMP-7 as a novel diagnostic biomarker in esophageal squamous cell carcinoma.

    abstract:AIM:To evaluate the diagnostic values of serum autoantibodies against matrix metalloproteinase-7 (MMP-7) in patients with esophageal squamous cell carcinoma (ESCC). METHODS:The MMP-7 cDNA was cloned from ESCC tissues, and MMP-7 was expressed and purified from a prokaryotic system. MMP-7 autoantibodies were then measur...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i10.1373

    authors: Zhou JH,Zhang B,Kernstine KH,Zhong L

    更新日期:2011-03-14 00:00:00

  • Construction of targeted plasmid vector pcDNA3.1-Egr.1p-p16 and its expression in pancreatic cancer JF305 cells induced by radiation in vitro.

    abstract:AIM:To construct pcDNA3.1-Egr.1p-p16 recombinant plasmid and investigate the expression of p16 in pancreatic cancer JF305 cells induced by radiation and the feasibility of gene radiotherapy for pancreatic carcinoma. METHODS:Human p16 cDNA was ligated to the downstream of Egr-1 promotor to construct pcDNA3.1-Egr.1p-p16...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i31.4214

    authors: Ma HB,Wang XJ,Di ZL,Xia H,Li Z,Liu J,Ma J,Kang HF,Wu CM,Bai MH

    更新日期:2007-08-21 00:00:00

  • International guidelines for the management of pancreatic intraductal papillary mucinous neoplasms.

    abstract::The management of intraductal papillary mucinous neoplasms (IPMN) is presently evolving as a result of the improved understanding of the natural history and biological behavior of the different pancreatic cystic neoplasms; and better preoperative diagnosis of these neoplasms due to advancement in preoperative diagnost...

    journal_title:World journal of gastroenterology

    pub_type: 社论

    doi:10.3748/wjg.v21.i34.9833

    authors: Goh BK

    更新日期:2015-09-14 00:00:00

  • Efficacy and safety of gemcitabine-based chemotherapies in biliary tract cancer: a meta-analysis.

    abstract:AIM:To investigate the efficacy and safety of gemcitabine (Gem)-based combination chemotherapies for the treatment of advanced biliary tract cancer. METHODS:Clinical trials were identified by searching scientific literature databases (PubMed, EMBASE and the Cochrane Library) for studies published between 1975 and 2013...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审

    doi:10.3748/wjg.v20.i47.18001

    authors: Liu H,Zhang QD,Li ZH,Zhang QQ,Lu LG

    更新日期:2014-12-21 00:00:00

  • Role of mucosal dendritic cells in inflammatory bowel disease.

    abstract::The gastrointestinal innate and adaptive immune system continuously faces the challenge of potent stimuli from the commensal microflora and food constituents. These local immune responses require a tight control, the outcome of which is in most cases the induction of tolerance. Local T cell immunity is an important co...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.14.5138

    authors: Niess JH

    更新日期:2008-09-07 00:00:00

  • A unique case of collagenous colitis presenting as protein-losing enteropathy successfully treated with prednisolone.

    abstract::A 76-year-old woman with a 5-mo history of recurrent diarrhea and generalized edema was admitted to our hospital. Colonoscopy revealed edematous mucosa, and histopathological examination was compatible with collagenous colitis. Protein leakage from the colon, particularly in the ascending portion, was identified on 99...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.6083

    authors: Sano S,Yamagami K,Tanaka A,Nishio M,Nakamura T,Kubo Y,Inoue T,Ueda W,Okawa K,Yoshioka K

    更新日期:2008-10-21 00:00:00

  • Autoimmune pancreatitis: a review.

    abstract::Autoimmune pancreatitis has emerged over the last 40 years from a proposed concept to a well established and recognized entity. As an efficient mimicker of pancreatic carcinoma, its early and appropriate recognition are crucial. With mounting understanding of its pathogenesis and natural history, significant advances ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v13.i47.6327

    authors: Zandieh I,Byrne MF

    更新日期:2007-12-21 00:00:00

  • Catheter tract implantation metastases associated with percutaneous biliary drainage for extrahepatic cholangiocarcinoma.

    abstract:AIM:To estimate the incidence of catheter tract implantation metastasis among patients undergoing percutaneous transhepatic biliary drainage (PTBD) for extrahepatic cholangiocarcinoma, and to provide data regarding the management of this unusual complication of PTBD by reviewing cases reported in the literature. METHO...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i44.7024

    authors: Sakata J,Shirai Y,Wakai T,Nomura T,Sakata E,Hatakeyama K

    更新日期:2005-11-28 00:00:00

  • Fenofibrate for patients with asymptomatic primary biliary cirrhosis.

    abstract:AIM:Primary biliary cirrhosis (PBC) is a chronic, cholestatic disease of autoimmune etiology, the histology of which shows a destruction of the intrahepatic bile duct and portal inflammation. Ursodeoxycholic acid (UDCA) is now used as a first-line drug for asymptomatic PBC (aPBC) because it is reported that UDCA decrea...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.v10.i6.894

    authors: Dohmen K,Mizuta T,Nakamuta M,Shimohashi N,Ishibashi H,Yamamoto K

    更新日期:2004-03-15 00:00:00

  • Overexpression of c-fos in Helicobacter pylori-induced gastric precancerosis of Mongolian gerbil.

    abstract:AIM:To explore dysregulation of c-fos in several human malignancies, and to further investigate the role of c-fos in Helicobacter pylori (H. pylori)-induced gastric precancerosis. METHODS:Four-week-old male Mongolian gerbils were employed in the study. 0.5 mL 1X10(8) cfu/L suspension of H. pylori NCTC 11 637 in Brucel...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i3.521

    authors: Yang YL,Xu B,Song YG,Zhang WD

    更新日期:2003-03-01 00:00:00

  • Enterolithiasis.

    abstract::Enterolithiasis or formation of gastrointestinal concretions is an uncommon medical condition that develops in the setting of intestinal stasis in the presence of the intestinal diverticula, surgical enteroanastomoses, blind pouches, afferent loops, incarcerated hernias, small intestinal tumors, intestinal kinking fro...

    journal_title:World journal of gastroenterology

    pub_type: 历史文章,杂志文章,评审

    doi:10.3748/wjg.v20.i47.17819

    authors: Gurvits GE,Lan G

    更新日期:2014-12-21 00:00:00

  • Peritoneal carcinomatosis of colorectal origin: Incidence, prognosis and treatment options.

    abstract::Peritoneal carcinomatosis (PC) is one manifestation of metastatic colorectal cancer (CRC). Tumor growth on intestinal surfaces and associated fluid accumulation eventually result in bowel obstruction and incapacitating levels of ascites, which profoundly affect the quality of life for affected patients. PC appears res...

    journal_title:World journal of gastroenterology

    pub_type: 社论

    doi:10.3748/wjg.v18.i39.5489

    authors: Klaver YL,Lemmens VE,Nienhuijs SW,Luyer MD,de Hingh IH

    更新日期:2012-10-21 00:00:00

  • Comorbidity in inflammatory bowel disease.

    abstract::Patients with inflammatory bowel disease (IBD) can be affected by other unrelated diseases. These are called comorbid conditions, and can include any secondary health problem that affects a person suffering from a primary or main disease, and which is neither linked physiopathologically to the primary condition, nor i...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v17.i22.2723

    authors: Román AL,Muñoz F

    更新日期:2011-06-14 00:00:00

  • Anal metastasis from recurrent breast lobular carcinoma: a case report.

    abstract::We report a case of isolated gastrointestinal metastasis from breast lobular carcinoma, which mimicked primary anal cancer. In July 2000, an 88-year-old woman presented with infiltrating lobular cancer (pT1/G2/N2). The patient received postoperative radiotherapy and hormonal therapy. Four years later, she presented wi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.1388

    authors: Puglisi M,Varaldo E,Assalino M,Ansaldo G,Torre G,Borgonovo G

    更新日期:2009-03-21 00:00:00

  • Relationship between serum calcium and CA 19-9 levels in colorectal cancer.

    abstract:AIM:To examine the calcium metabolism of colorectal cancer (CRC) in patients with colorectal cancer and control patients. METHODS:Seventy newly diagnosed CRC patients were included. The healthy control group was age and gender matched (n=32). Particular attention was devoted to the relationship between serum calcium o...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i13.1890

    authors: Fuszek P,Lakatos P,Tabak A,Papp J,Nagy Z,Takacs I,Horvath HC,Lakatos PL,Speer G

    更新日期:2004-07-01 00:00:00

  • Pulmonary manifestations of inflammatory bowel disease.

    abstract::Extraintestinal manifestations of inflammatory bowel disease (IBD) are a systemic illness that may affect up to half of all patients. Among the extraintestinal manifestations of IBD, those involving the lungs are relatively rare and often overlooked. However, there is a wide array of such manifestations, spanning from...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i37.13501

    authors: Ji XQ,Wang LX,Lu DG

    更新日期:2014-10-07 00:00:00

  • Clinical management of acute liver failure: Results of an international multi-center survey.

    abstract:AIM:To assess the practice of caring for acute liver failure (ALF) patients in varying geographic locations and medical centers. METHODS:Members of the European Acute Liver Failure Consortium completed an 88-item questionnaire detailing management of ALF. Responses from 22 transplantation centers in 11 countries were ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v22.i33.7595

    authors: Rabinowich L,Wendon J,Bernal W,Shibolet O

    更新日期:2016-09-07 00:00:00

  • Therapeutic plasma exchange in patients with hyperlipidemic pancreatitis.

    abstract:AIM:To clarify the effectiveness of plasma exchange by comparing the mortality and morbidity before and after the intervention of plasma exchange. METHODS:Plasma exchange has been available as an optional therapy for hyperlipidemic pancreatitis since August 1999 in our hospital. The patients were assorted into 2 group...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.v10.i15.2272

    authors: Chen JH,Yeh JH,Lai HW,Liao CS

    更新日期:2004-08-01 00:00:00

  • Inflammatory bowel disease associated neoplasia: A surgeon's perspective.

    abstract::Inflammatory bowel disease (IBD) is associated with increased risk of colorectal cancer (CRC). The risk is known to increase with longer duration of the disease, family history of CRC, and history of primary sclerosing cholangitis. The diagnosis of the neoplastic changes associated with IBD is difficult owing to the h...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i3.961

    authors: Althumairi AA,Lazarev MG,Gearhart SL

    更新日期:2016-01-21 00:00:00