New technologies in gastrointestinal research.

Abstract:

:This issue presents different new techniques aiming to increase our understanding of the gastrointestinal system and to improve treatment. The technologies cover selected methods to evoke and assess gut pain, new methods for imaging and physiological measurements, histochemistry, pharmacological modelling etc. There is no doubt that the methods will revolutionize the diagnostic approach in near future.

journal_name

World J Gastroenterol

authors

Drewes AM,Gregersen H

doi

10.3748/wjg.15.129

subject

Has Abstract

pub_date

2009-01-14 00:00:00

pages

129-30

issue

2

eissn

1007-9327

issn

2219-2840

journal_volume

15

pub_type

社论
  • Polymorphism of glutathione S-transferase mu 1 and theta 1 genes and hepatocellular carcinoma in southern Guangxi, China.

    abstract:AIM:Glutathione S-transferase mu 1 (GSTM1) and theta 1 (GSTT1) genes are involved in the metabolism of a wide range of carcinogens, but deletions of the genes are commonly found in the population. The present study was undertaken to evaluate the association between GSTM1 and GSTT1 gene polymorphisms and hepatocellular ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i2.272

    authors: Deng ZL,Wei YP,Ma Y

    更新日期:2005-01-14 00:00:00

  • Preliminary study on proteomics of gastric carcinoma and its clinical significance.

    abstract:AIM:To explore the preliminary identification of serum protein pattern models that may be novel potential biomarkers in the detection of gastric cancer. METHODS:A total of 130 serum samples, including 70 from patients with gastric cancer and 60 from healthy adults, were detected by surface-enhanced laser desorption an...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i40.6249

    authors: Qian HG,Shen J,Ma H,Ma HC,Su YH,Hao CY,Xing BC,Huang XF,Shou CC

    更新日期:2005-10-28 00:00:00

  • Quantitative analysis of transforming growth factor beta 1 mRNA in patients with alcoholic liver disease.

    abstract:AIM:To investigate the expression of the transforming growth factor beta 1(TGF-beta 1) mRNA in different stages of alcoholic liver disease (ALD) and its clinical value. METHODS:One hundred and seven male alcoholics were grouped by clinical findings into four groups: alcohol abusers without liver impairment (n =22), al...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v8.i2.379

    authors: Chen WX,Li YM,Yu CH,Cai WM,Zheng M,Chen F

    更新日期:2002-04-01 00:00:00

  • Protocol for laparoscopic cholecystectomy: Is it rocket science?

    abstract::Laparoscopic cholecystectomy (LC) does not require advanced techniques, and its performance has therefore rapidly spread worldwide. However, the rate of biliary injuries has not decreased. The concept of the critical view of safety (CVS) was first documented two decades ago. Unexpected injuries are principally due to ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i47.10287

    authors: Hori T,Oike F,Furuyama H,Machimoto T,Kadokawa Y,Hata T,Kato S,Yasukawa D,Aisu Y,Sasaki M,Kimura Y,Takamatsu Y,Naito M,Nakauchi M,Tanaka T,Gunji D,Nakamura K,Sato K,Mizuno M,Iida T,Yagi S,Uemoto S,Yoshimura T

    更新日期:2016-12-21 00:00:00

  • Hepatitis C virus genotypes distribution and transmission risk factors in Luxembourg from 1991 to 2006.

    abstract:AIM:To analyze the Hepatitis C virus (HCV) genotype distribution and transmission risk factors in a population of unselected patients in Luxembourg. METHODS:Epidemiological information (gender, age and transmission risks) were collected from 802 patients newly diagnosed for hepatitis C and living in Luxembourg, among ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.1237

    authors: Roman F,Hawotte K,Struck D,Ternes AM,Servais JY,Arendt V,Hoffman P,Hemmer R,Staub T,Seguin-Devaux C,Schmit JC

    更新日期:2008-02-28 00:00:00

  • Effectiveness of exercise in hepatic fat mobilization in non-alcoholic fatty liver disease: Systematic review.

    abstract:AIM:To investigate the efficacy of exercise interventions on hepatic fat mobilization in non-alcoholic fatty liver disease (NAFLD) patients. METHODS:Ovid-Medline, PubMed, EMBASE and Cochrane database were searched for randomized trials and prospective cohort studies in adults aged ≥ 18 which investigated the effects o...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i27.6318

    authors: Golabi P,Locklear CT,Austin P,Afdhal S,Byrns M,Gerber L,Younossi ZM

    更新日期:2016-07-21 00:00:00

  • The spirit of Henry Norman Bethune and gastroenterology.

    abstract::Henry Norman Bethune was a physician and surgeon from Canada. He had a highly impressive medical career in Montreal but did his most important work in China where he cared for soldiers on the battlefield. He died in 1939 and was recognized as a hero, but only much later received recognition in Canada. He was a skilled...

    journal_title:World journal of gastroenterology

    pub_type: 传,历史文章,杂志文章

    doi:10.3748/wjg.14.174

    authors: Freeman HJ

    更新日期:2008-01-14 00:00:00

  • Pre-hepatectomy type IV collagen 7S predicts post-hepatectomy liver failure and recovery.

    abstract:BACKGROUND:Liver resection is an effective treatment for benign and malignant liver tumors. However, a method for preoperative evaluation of hepatic reserve has not yet been established. Previously reported assessments of preoperative hepatic reserve focused only on liver failure in the early postoperative period and d...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v26.i7.725

    authors: Ishii M,Itano O,Shinoda M,Kitago M,Abe Y,Hibi T,Yagi H,Takeuchi A,Tsujikawa H,Abe T,Kitagawa Y

    更新日期:2020-02-21 00:00:00

  • Postprandial transduodenal bolus transport is regulated by complex peristaltic sequence.

    abstract:AIM:To study the relationship between the patterns of postprandial peristalsis and transduodenal bolus transport in healthy subjects. METHODS:Synchronous recording of chyme transport and peristaltic activity was performed during the fasting state and after administration of a test meal using a special catheter device ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i37.6008

    authors: Nguyen HN,Winograd R,Domingues GR,Lammert F

    更新日期:2006-10-07 00:00:00

  • Dynamic changes of key metabolites during liver fibrosis in rats.

    abstract:BACKGROUND:Fibrosis is the single most important predictor of significant morbidity and mortality in patients with chronic liver disease. Established non-invasive tests for monitoring fibrosis are lacking, and new biomarkers of liver fibrosis and function are needed. AIM:To depict the process of liver fibrosis and loo...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v25.i8.941

    authors: Yu J,He JQ,Chen DY,Pan QL,Yang JF,Cao HC,Li LJ

    更新日期:2019-02-28 00:00:00

  • Chemotherapy for transarterial chemoembolization in patients with unresectable hepatocellular carcinoma.

    abstract:AIM:To compare the efficacy of different chemotherapeutic agents during conventional transarterial chemoembolization (cTACE) in the treatment of unresectable hepatocellular carcinoma (HCC). METHODS:A retrospective review was undertaken of patients with unresectable HCC undergoing cTACE from May 2003 to November 2011. ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i31.10960

    authors: Wu J,Song L,Zhao DY,Guo B,Liu J

    更新日期:2014-08-21 00:00:00

  • Bacterial flora concurrent with Helicobacter pylori in the stomach of patients with upper gastrointestinal diseases.

    abstract:AIM:To investigate the non-Helicobacter pylori (H. pylori) bacterial flora concurrent with H. pylori infection. METHODS:A total of 103 gastric biopsy specimens from H. pylori positive patients were selected for bacterial culture. All the non-H. pylori bacterial isolates were identified by matrix-assisted laser desorpt...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i11.1257

    authors: Hu Y,He LH,Xiao D,Liu GD,Gu YX,Tao XX,Zhang JZ

    更新日期:2012-03-21 00:00:00

  • Improvement of type 2 diabetes mellitus after gastric cancer surgery: short-term outcome analysis after gastrectomy.

    abstract:AIM:To evaluate the effect of gastrectomy on diabetes control in patients with type 2 diabetes mellitus and early gastric cancer. METHODS:Data from 64 patients with early gastric cancer and type 2 diabetes mellitus were prospectively collected. All patients underwent curative gastrectomy (36 subtotal gastrectomy with ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i48.9410

    authors: An JY,Kim YM,Yun MA,Jeon BH,Noh SH

    更新日期:2013-12-28 00:00:00

  • Effects of autoantibodies against beta(1)-adrenoceptor in hepatitis virus myocarditis on action potential and L-type Ca(2+) currents.

    abstract:AIM:To investigate the effects of autoantibodies against beta(1)-adrenoceptor in hepatitis virus myocarditis on action potential and L-type Ca(2+) currents. METHODS:Fifteen samples of autoantibodies against beta(1)-adrenoceptor positive sera of patients with hepatitis virus myocarditis were obtained and IgGs were puri...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i8.1171

    authors: Liu K,Liao YH,Wang ZH,Li SL,Wang M,Zeng LL,Tang M

    更新日期:2004-04-15 00:00:00

  • Sub-classification of intermediate-stage (Barcelona Clinic Liver Cancer stage-B) hepatocellular carcinomas.

    abstract::Hepatocellular carcinoma (HCC), the fifth most common cancer in the world, shows increasing incidence worldwide. Curative treatments such as hepatectomy, liver transplantation, and radiofrequency ablation are applied in only 30%-60% of cases. Most remaining patients receive transarterial chemoembolization (TACE). Pati...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v21.i37.10604

    authors: Yamakado K,Hirota S

    更新日期:2015-10-07 00:00:00

  • Prognostic value of KIT mutation in gastrointestinal stromal tumors.

    abstract:AIM:To examine the prevalence and prognostic significance of C-kit gene mutation and analysis the correlation of C-kit gene mutation and the clinicalpathologic parameters of GISTs. METHODS:Eighty-two GISTs were studied for the mutation of C-kit gene by PCR-SSCP, DNA sequence. Statistical comparison were used to analys...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i25.3948

    authors: Liu XH,Bai CG,Xie Q,Feng F,Xu ZY,Ma DL

    更新日期:2005-07-07 00:00:00

  • Abdominal paracentesis drainage ameliorates severe acute pancreatitis in rats by regulating the polarization of peritoneal macrophages.

    abstract:AIM:To investigate the role of peritoneal macrophage (PM) polarization in the therapeutic effect of abdominal paracentesis drainage (APD) on severe acute pancreatitis (SAP). METHODS:SAP was induced by 5% Na-taurocholate retrograde injection in Sprague-Dawley rats. APD was performed by inserting a drainage tube with a ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v24.i45.5131

    authors: Liu RH,Wen Y,Sun HY,Liu CY,Zhang YF,Yang Y,Huang QL,Tang JJ,Huang CC,Tang LJ

    更新日期:2018-12-07 00:00:00

  • Difference in DRB1* gene polymorphisms between Han and Uyghur ulcerative colitis patients in China.

    abstract:AIM:To evaluate the association between HLA-DRB1 alleles and Han and Uyghur ulcerative colitis (UC) patients residing in the Xinjiang Uyghur Autonomous Region of China. METHODS:In this study, 102 UC patients (53 Han including 22 men and 31 women, and 49 Uyghur patients including 25 men and 24 women; aged 48.07 ± 15.83...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i17.2709

    authors: Aheman A,Gao F,Kuerbanjiang A,Li YX,Abuduhadeer M

    更新日期:2013-05-07 00:00:00

  • Towards curative therapy in gastric cancer: Faraway, so close!

    abstract::Although recent diagnostic and therapeutic advances have substantially improved the survival of patients with gastric cancer (GC), the overall prognosis is still poor. Surgery is the only curative treatment and should be performed in experienced centers. Due to high relapse following surgery, complementary and systemi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v21.i41.11609

    authors: Cravo M,Fidalgo C,Garrido R,Rodrigues T,Luz G,Palmela C,Santos M,Lopes F,Maio R

    更新日期:2015-11-07 00:00:00

  • Cryptogenic multifocal ulcerous stenosing enteritis: Radiologic features and clinical behavior.

    abstract:AIM:To investigate the characteristic radiologic findings of cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) which can be differentiated from other similar bowel disease and to assess their clinical behavior. METHODS:Twenty pathologically and clinically confirmed CMUSE patients (males:females = 8:12; mean ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i25.4615

    authors: Hwang J,Kim JS,Kim AY,Lim JS,Kim SH,Kim MJ,Kim MS,Song KD,Woo JY

    更新日期:2017-07-07 00:00:00

  • Diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index and liver stiffness measurement in hepatitis B virus-infected patients with persistently normal alanine aminotransferase.

    abstract:AIM:To assess the diagnostic value of FIB-4, aspartate aminotransferase-to-platelet ratio index (APRI), and liver stiffness measurement (LSM) in patients with hepatitis B virus infection who have persistently normal alanine transaminase (PNALT). METHODS:We enrolled 245 patients with chronic hepatitis B: 95 in PNALT gr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i31.5746

    authors: Tan YW,Zhou XB,Ye Y,He C,Ge GH

    更新日期:2017-08-21 00:00:00

  • Sexual health and fertility for individuals with inflammatory bowel disease.

    abstract::The impact of a chronic disease such as inflammatory bowel disease (IBD) on sexual functioning and body image can significantly impair the quality of life of patients. This review considers the sexual and fertility aspects of IBD patients and their daily management. Modern IBD healthcare management should include appr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v25.i36.5423

    authors: Leenhardt R,Rivière P,Papazian P,Nion-Larmurier I,Girard G,Laharie D,Marteau P

    更新日期:2019-09-28 00:00:00

  • Interruption of HBV intrauterine transmission: a clinical study.

    abstract:AIM:To investigate the effect of hepatitis B virus (HBV) specific immunoglobin (HBIG) and lamivudine on HBV intrauterine transmission in HBsAg positive pregnant women. METHODS:Each subject in the HBIG group (56 cases) was given 200 IU HBIG intramuscularly (im.) every 4 weeks from 28-week (wk) of gestation, while each ...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.v9.i7.1501

    authors: Li XM,Yang YB,Hou HY,Shi ZJ,Shen HM,Teng BQ,Li AM,Shi MF,Zou L

    更新日期:2003-07-01 00:00:00

  • Nimesulide inhibits proliferation via induction of apoptosis and cell cycle arrest in human gastric adenocarcinoma cell line.

    abstract:AIM:To evaluate the potential role of Nimesulide, a selective COX-2 inhibitor, in proliferation and apoptosis of gastric adenocarcinoma cells SGC7901. METHODS:Cell counts and MTT assay were used to quantify the influence of Nimesulide in the proliferation of SGC7901 cells. Transmission electron microscopy and flow cyt...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i5.915

    authors: Li JY,Wang XZ,Chen FL,Yu JP,Luo HS

    更新日期:2003-05-01 00:00:00

  • Enhanced expressions and activations of leukotriene C4 synthesis enzymes in D-galactosamine/lipopolysaccharide-induced rat fulminant hepatic failure model.

    abstract:AIM:To investigate the expression and activity of leukotriene C4 (LTC4) synthesis enzymes and their underlying relationship with cysteinyl leukotriene (cys-LT) generation in a rat fulminant hepatic failure (FHF) model induced by D-galactosamine/lipopolysaccharide (D-GalN/ LPS). METHODS:Rats were treated with D-GalN (3...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.2748

    authors: Ma KF,Yang HY,Chen Z,Qi LY,Zhu DY,Lou YJ

    更新日期:2008-05-07 00:00:00

  • Resolution of chronic hepatitis C following parasitosis.

    abstract::An inefficient cellular immune response likely leads to chronic hepatitis C virus (HCV) infection. Resolution of chronic HCV infection in the absence of treatment is a rare occurrence. We report the case of a 39-year old white male with a 17-year history of chronic HCV infection, who eradicated HCV following a serious...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i31.4268

    authors: Byrnes V,Chopra S,Koziel MJ

    更新日期:2007-08-21 00:00:00

  • Effect of Helicobacter pylori infection on gastric mucosal pathologic change and level of nitric oxide and nitric oxide synthase.

    abstract:AIM:To investigate the level of nitric oxide (NO) and nitrous oxide synthase (NOS) enzyme and its effect on gastric mucosal pathologic change in patients infected with Helicobacter pylori (H pylori), and to study the pathogenic mechanism of H pylori. METHODS:The mucosal tissues of gastric antrum were taken by endoscop...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i32.5029

    authors: Wang YF,Guo CL,Zhao LZ,Yang GA,Chen P,Wang HK

    更新日期:2005-08-28 00:00:00

  • Impact of small-for-size liver grafts on medium-term and long-term graft survival in living donor liver transplantation: A meta-analysis.

    abstract:BACKGROUND:Small-for-size grafts (SFSGs) in living donor liver transplantation (LDLT) could optimize donor postoperative outcomes and also expand the potential donor pool. Evidence on whether SFSGs would affect medium-term and long-term recipient graft survival is lacking. AIM:To evaluate the impact of small-for-size ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.3748/wjg.v25.i36.5559

    authors: Ma KW,Wong KHC,Chan ACY,Cheung TT,Dai WC,Fung JYY,She WH,Lo CM,Chok KSH

    更新日期:2019-09-28 00:00:00

  • Approach to the endoscopic resection of duodenal lesions.

    abstract::Duodenal polyps or lesions are uncommonly found on upper endoscopy. Duodenal lesions can be categorized as subepithelial or mucosally-based, and the type of lesion often dictates the work-up and possible therapeutic options. Subepithelial lesions that can arise in the duodenum include lipomas, gastrointestinal stromal...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i2.600

    authors: Gaspar JP,Stelow EB,Wang AY

    更新日期:2016-01-14 00:00:00

  • A patient with spinal metastasis from hepatocellular carcinoma discovered from neurological findings.

    abstract::Although spinal tumors are uncommon, they may reduce survival or cause serious functional disorders in the extremities. Metastatic spinal tumors from malignant tumors can induce symptoms of spinal cord compression, such as paraplegia, quadriplegia, and vesicorectal disturbance, which are aggravated with progression of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v13.i19.2758

    authors: Tamaki K,Shimizu I,Urata M,Kohno N,Fukuno H,Ito S,Sano N

    更新日期:2007-05-21 00:00:00