Prognostic value of KIT mutation in gastrointestinal stromal tumors.

abstract：AIM:To explore the grade and stage of pathology and the relationship between grading and staging of hepatic fibrosis and noninvasive diagnostic parameters. METHODS:Inflammatory activity and fibrosis of consecutive liver biopsies from 200 patients with chronic liver disease were determined according to the Diagnostic C...

journal_title：World journal of gastroenterology

authors： Lu LG,Zeng MD,Wan MB,Li CZ,Mao YM,Li JQ,Qiu DK,Cao AP,Ye J,Cai X,Chen CW,Wang JY,Wu SM,Zhu JS,Zhou XQ

更新日期：2003-11-01 00:00:00

abstract：AIM:To evaluate the diagnostic value of gadobenate dimeglumine (Gd-BOPTA)-enhanced hepatocyte-phase magnetic resonance imaging (MRI) in evaluating hepatic fibrosis and hepatitis. METHODS:Hepatocyte-phase images of Gd-BOPTA-enhanced MRI were retrospectively evaluated in 76 patients with chronic liver disease. These pat...

journal_title：World journal of gastroenterology

authors： Li XM,Chen Z,Xiao EH,Shang QL,Ma C

更新日期：2017-05-07 00:00:00

abstract：AIM:To investigate the effects of guggulsterone on the proliferation and apoptosis of human hepatoma HepG2 cells in vitro and relevant mechanisms. METHODS:Human hepatocellular carcinoma HepG2 cells and normal human liver L-02 cells were treated with different concentrations of guggulsterone (5-100 μmol/L) for 24-72 h....

journal_title：World journal of gastroenterology

authors： Shi JJ,Jia XL,Li M,Yang N,Li YP,Zhang X,Gao N,Dang SS

更新日期：2015-12-21 00:00:00

abstract：:Endoscopic mucosal resection (EMR) allows the removal of flat or sessile lesions, laterally spreading tumors, and carcinoma of the colon or the rectum limited to the mucosa or the superficial submucosa. Acute appendicitis is the most common abdominal emergency requiring emergency surgery, and it is also a rare complic...

journal_title：World journal of gastroenterology

authors： Nemoto Y,Tokuhisa J,Shimada N,Gomi T,Maetani I

更新日期：2015-07-21 00:00:00

abstract：:Transplantation cannot be considered the most important therapeutic procedure for hepatocellular carcinoma (HCC). In France, no more than 2% of patients with HCC undergo a transplantation. Randomized controlled trial must assess the benefit to risk ratio of various potentially "curative" treatment procedures (transpla...

journal_title：World journal of gastroenterology

authors： Braillon A

更新日期：2009-11-14 00:00:00

abstract：AIM:To explore the inducing effect of human mutant p27 gene on the apoptosis of the human gastric cancer cell line MKN-45 and its associated mechanisms. METHODS:The recombinant adenovirus Ad-p27mt was constructed to infect the human gastric cancer cell line MKN-45. Using flow cytometry, TUNEL assay and DNA fragment an...

journal_title：World journal of gastroenterology

authors： Zhu JS,Wang L,Cheng GQ,Li Q,Zhu ZM,Zhu L

更新日期：2005-12-21 00:00:00

abstract：AIM:To investigate the dynamic features of insulin-like growth factor-I receptor (IGF-IR) expression in rat hepatocarcinogenesis, and the relationship between IGF-IR and hepatocytes malignant transformation at mRNA or protein level. METHODS:Hepatoma models were made by inducing with 2-fluorenylacetamide (2-FAA) on mal...

journal_title：World journal of gastroenterology

authors： Yan XD,Yao M,Wang L,Zhang HJ,Yan MJ,Gu X,Shi Y,Chen J,Dong ZZ,Yao DF

更新日期：2013-09-28 00:00:00

abstract：AIM:To investigate changes in vasoactive intestinal polypeptide (VIP) and corticotrophin releasing factor (CRF) in the plasma and duodenum of chronic stress-induced depressed rats and the effects of fluoxetine hydrochloride (fluoxetine) treatment on depression-induced changes in VIP and CRF. METHODS:A Sprague-Dawley r...

journal_title：World journal of gastroenterology

authors： Huang YL,Yu JP,Wang GH,Chen ZH,Wang Q,Xiao L

更新日期：2007-12-07 00:00:00

abstract：:Non-HFE hereditary haemochromatosis (HH) refers to a genetically heterogeneous group of iron overload disorders that are unlinked to mutations in the HFE gene. The four main types of non-HFE HH are caused by mutations in the hemojuvelin, hepcidin, transferrin receptor 2 and ferroportin genes. Juvenile haemochromatosis...

journal_title：World journal of gastroenterology

authors： Wallace DF,Subramaniam VN

更新日期：2007-09-21 00:00:00

abstract：:Ulcerative colitis (UC) is an inflammatory destructive disease of the large intestine occurred usually in the rectum and lower part of the colon as well as the entire colon. Drug therapy is not the only choice for UC treatment and medical management should be as a comprehensive whole. Azulfidine, Asacol, Pentasa, Dipe...

journal_title：World journal of gastroenterology

authors： Xu CT,Meng SY,Pan BR

更新日期：2004-08-15 00:00:00

abstract：AIM:To clarify the role of serum anti-Helicobacter pylori (H. pylori) antibody titers in gastric cancer. METHODS:In this cross-sectional study, the effect of patients' baseline characteristics and endoscopic findings on their serum antibody titers were assessed. We evaluated consecutive patients who underwent esophago...

journal_title：World journal of gastroenterology

authors： Toyoshima O,Nishizawa T,Sakitani K,Yamakawa T,Takahashi Y,Yamamichi N,Hata K,Seto Y,Koike K,Watanabe H,Suzuki H

更新日期：2018-09-21 00:00:00

abstract：AIM:To evaluate the agreement of multichannel intraluminal impedance-pH monitoring (MII-pHM) and gastroesophageal reflux scintigraphy (GES) for the diagnosis of gastroesophageal reflux disease. METHODS:Seventy-five consecutive patients with suspected gastroesophageal reflux disease (GERD) underwent 24-h combined MII-p...

journal_title：World journal of gastroenterology

authors： Uslu Kızılkan N,Bozkurt MF,Saltık Temizel IN,Demir H,Yüce A,Caner B,Özen H

更新日期：2016-11-21 00:00:00

abstract：BACKGROUND:The management strategies for recurrent ampullary adenoma after endoscopic papillectomy are still controversial. Patients with the recurrent papillary lesions need to receive repetitive endoscopic interventions due to the limitations of conventional endoscopic techniques. AIM:To assess the feasibility, effi...

journal_title：World journal of gastroenterology

authors： Wang ZK,Liu F,Wang Y,Wang XD,Tang P,Li W

更新日期：2020-10-07 00:00:00

abstract：AIM:To evaluate the effect of the natural diterpenoid, hypoestoxide (HE) on the growth of established colon cancer in mice. METHODS:The CT26.WT mouse colon carcinoma cell line was grown and expanded in vitro. Following the expansion, BALB/c mice were inoculated s.c. with viable tumor cells. After the tumors had establ...

journal_title：World journal of gastroenterology

authors： Ojo-Amaize EA,Cottam HB,Oyemade OA,Okogun JI,Nchekwube EJ

更新日期：2007-09-14 00:00:00

abstract：:The occurrence of pancreatic pleural effusion, secondary to an internal pancreatic fistula, is a rare clinical syndrome and diagnosis is often missed. The key to the diagnosis is a dramatically elevated pleural fluid amylase. This pancreatic pleural effusion is also called a pancreatic pleural fistula. It is character...

journal_title：World journal of gastroenterology

authors： Jin SG,Chen ZY,Yan LN,Zeng Y

更新日期：2010-09-21 00:00:00

abstract：AIM:To compare the efficacy and safety of single daily amikacin vs. cefotaxime in the 5-d treatment of spontaneous bacterial peritonitis (SBP). METHODS:Thirty-seven cirrhotic patients with SBP, 19 in group A and 18 in group B, were studied. Group A received 1 g of cefotaxime every 6 h, and group B received 500 mg of a...

journal_title：World journal of gastroenterology

authors： Chen TA,Lo GH,Lai KH,Lin WJ

更新日期：2005-11-21 00:00:00

abstract：:A Killian-Jamieson diverticulum (KJD) is an unfamiliar and rare cervical esophageal diverticulum. This diverticulum originates on the anterolateral wall of the proximal cervical esophagus through a muscular gap (the Killian-Jamieson space) below the cricopharyngeal muscle and lateral to the longitudinal muscle of the ...

journal_title：World journal of gastroenterology

authors： Lee CK,Chung IK,Park JY,Lee TH,Lee SH,Park SH,Kim HS,Kim SJ

更新日期：2008-11-14 00:00:00

abstract：:We report a case of isolated gastrointestinal metastasis from breast lobular carcinoma, which mimicked primary anal cancer. In July 2000, an 88-year-old woman presented with infiltrating lobular cancer (pT1/G2/N2). The patient received postoperative radiotherapy and hormonal therapy. Four years later, she presented wi...

journal_title：World journal of gastroenterology

authors： Puglisi M,Varaldo E,Assalino M,Ansaldo G,Torre G,Borgonovo G

更新日期：2009-03-21 00:00:00

abstract：AIM:To improve the technique of tissue microarray (tissue chip). METHODS:A new tissue microarraying method was invented with a common microscope installed with a special holing needle, a sampling needle, and a special box fixing paraffin blocks on the microscope slide carrier. With the movement of microscope tube and ...

journal_title：World journal of gastroenterology

authors： Dan HL,Zhang YL,Zhang Y,Wang YD,Lai ZS,Yang YJ,Cui HH,Jian YT,Geng J,Ding YQ,Guo CH,Zhou DY

更新日期：2004-02-15 00:00:00

abstract：AIM:To evaluate the protective effect of NF-kappaB decoy oligodeoxynucleotides (ODNs) on ischemia/reperfusion (I/R) injury in rat liver graft. METHODS:Orthotopic syngeneic rat liver transplantation was performed with 3 h of cold preservation of liver graft in University of Wisconsin solution containing phosphorothioat...

journal_title：World journal of gastroenterology

authors： Xu MQ,Shuai XR,Yan ML,Zhang MM,Yan LN

更新日期：2005-11-28 00:00:00

abstract：BACKGROUND:The digestive tract is the maximal immunizing tissue in the body, and mucosal integrity and functional status of the gut is very important to maintain a healthy organism. Severe infection is one of the most common causes of gastrointestinal dysfunction, and the pathogenesis is closely related to endotoxemia ...

journal_title：World journal of gastroenterology

authors： Wang W,Sun M,Zheng YL,Sun LY,Qu SQ

更新日期：2019-06-21 00:00:00

abstract：AIM:To test whether ethanol feeding could induce Toll-like receptor 4 (TLR4) responses, assess the hepatoprotective effect of betaine and its inhibitive effect on TLR4 in animal models of alcoholic liver injury. METHODS:Forty-eight female Sprague-Dawley rats were randomly divided into four groups as control, model, lo...

journal_title：World journal of gastroenterology

authors： Shi QZ,Wang LW,Zhang W,Gong ZJ

更新日期：2010-02-21 00:00:00

abstract：AIM:To study the expression of a disintegrin and metalloproteinase 17 (ADAM17) mRNA in hepatocellular carcinoma (HCC) and to evaluate the relationship between ADAM17 mRNA expression and clinicopathological features of HCC. METHODS:Hepatocellular carcinomas (HCC) from 31 cases were divided into small HCC (SHCC), nodula...

journal_title：World journal of gastroenterology

authors： Ding X,Yang LY,Huang GW,Wang W,Lu WQ

更新日期：2004-09-15 00:00:00

abstract：AIM:To evaluate whether Helicobacter pylori (H. pylori) eradication therapy benefits patients with functional dyspepsia (FD). METHODS:Randomized controlled trials (RCTs) investigating the efficacy and safety of H. pylori eradication therapy for patients with functional dyspepsia published in English (up to May 2015) w...

journal_title：World journal of gastroenterology

authors： Du LJ,Chen BR,Kim JJ,Kim S,Shen JH,Dai N

更新日期：2016-03-28 00:00:00

abstract：AIM:To investigate the protective effect of stronger neo-minophafen C (SNMC) on fulminant hepatic failure (FHF) and its underlying mechanism. METHODS:A mouse model of FHF was established by intraperitoneal injection of galactosamine (D-Gal N) and lipopolysaccharide (LPS). The survival rate, liver function, inflammator...

journal_title：World journal of gastroenterology

authors： Yang BS,Ma YJ,Wang Y,Chen LY,Bi MR,Yan BZ,Bai L,Zhou H,Wang FX

更新日期：2007-01-21 00:00:00

abstract：:Video capsule endoscopy (CE) since its introduction 13 years back, has revolutionized our approach to small intestinal diseases. Obscure gastrointestinal bleed (OGIB) continues to be the most important indication for CE with a high sensitivity, specificity as well as positive and negative predictive values. It is best...

journal_title：World journal of gastroenterology

authors： Goenka MK,Majumder S,Goenka U

更新日期：2014-08-07 00:00:00

abstract：AIM:To examine the clinicopathologic features of elderly patients with gastric carcinoma and to investigate the relationship between prognosis and age. METHODS:We reviewed the hospital records of 2,014 patients with gastric carcinoma retrospectively to compare the clinicopathologic findings in elderly (age >70 years) ...

journal_title：World journal of gastroenterology

authors： Kim DY,Joo JK,Ryu SY,Park YK,Kim YJ,Kim SK

更新日期：2005-01-07 00:00:00

abstract：AIM:To investigate the accuracy of serum alanine aminotransferase (ALT) in diagnosing lamivudine resistance and factors that contributed to abnormal serum ALT. METHODS:This was a retrospective study of chronic hepatitis B patients on lamivudine therapy who were followed for 3-mo with liver function tests and hepatitis...

journal_title：World journal of gastroenterology

authors： Lim LG,Aung MO,Seet BL,Tan C,Dan YY,Lee YM,Sutedja DS,Fernandes M,Lee GH,Koay E,Lim SG

更新日期：2010-10-07 00:00:00

abstract：AIM:Granuloma is considered the hallmark of microscopic diagnosis in Crohn's disease (CD), but granulomas can be detected in only 21-60% of CD patients. The aim of this study was to evaluate the frequency of granulomas by multiple endoscopic biopsies in patients with CD and to examine whether group of patients with or ...

journal_title：World journal of gastroenterology

authors： Molnár T,Tiszlavicz L,Gyulai C,Nagy F,Lonovics J

更新日期：2005-05-28 00:00:00

abstract：AIM:To investigate the effect of synbiotics, i.e. probiotics and prebiotics mixture, on the gut microbial ecology and digestive enzyme activities in rats. METHODS:Forty-eight SD rats weighing about 280 g were used in this study. Rats were divided into three groups according to the contents of probiotics and prebiotics...

journal_title：World journal of gastroenterology

authors： Yang SC,Chen JY,Shang HF,Cheng TY,Tsou SC,Chen JR

更新日期：2005-12-21 00:00:00