Hypoestoxide inhibits tumor growth in the mouse CT26 colon tumor model.

abstract：:Primary biliary cirrhosis (PBC) is an autoimmune disease of the liver characterized by progressive bile duct destruction eventually leading to cirrhosis and liver failure. The serological hallmark of the disease is the presence of circulating antimitochondrial antibodies (AMA). These reflect the presence of autoreacti...

journal_title：World journal of gastroenterology

authors： Lleo A,Invernizzi P,Mackay IR,Prince H,Zhong RQ,Gershwin ME

更新日期：2008-06-07 00:00:00

abstract：AIM:To assess the clinicopathological and biological significance of cripto in human colorectal cancer. METHODS:Real-time reverse-transcription polymerase chain reaction (PCR) was used to examine cripto mRNA levels in primary colon cancer and normal colon tissues as well as normal and metastatic lymph nodes from colon...

journal_title：World journal of gastroenterology

authors： Jiang PC,Zhu L,Fan Y,Zhao HL

更新日期：2013-12-14 00:00:00

abstract：AIM:To investigate the roles of the adipocytokines, ghrelin and leptin in gastric cancer cachexia. METHODS:Resistin, ghrelin, leptin, adiponectin, insulin and insulin-like growth factor (IGF-I), were measured in 30 healthy subjects, and 60 gastric cancer patients of which 30 suffered from cancer-induced cachexia and 3...

journal_title：World journal of gastroenterology

authors： Kerem M,Ferahkose Z,Yilmaz UT,Pasaoglu H,Ofluoglu E,Bedirli A,Salman B,Sahin TT,Akin M

更新日期：2008-06-21 00:00:00

abstract：AIM:To determine the frequencies of HGV and TTV infections in serum and saliva samples of non-hepatitis patients with oral diseases in Hangzhou area, and to understand the correlation between detected results of HGV RNA and/or TTV DNA in sera and in saliva from the same patients. METHODS:RT-nested PCR for HGV RNA dete...

journal_title：World journal of gastroenterology

authors： Yan J,Chen LL,Lou YL,Zhong XZ

更新日期：2002-10-01 00:00:00

abstract：AIM:To investigate the molecular mechanism for regulation of cholesterol metabolism by hepatitis C virus (HCV) core protein in HepG2 cells. METHODS:HCV genotype 1b core protein was cloned and expressed in HepG2 cells. The cholesterol content was determined after transfection. The expression of sterol regulatory elemen...

journal_title：World journal of gastroenterology

authors： Li M,Wang Q,Liu SA,Zhang JQ,Ju W,Quan M,Feng SH,Dong JL,Gao P,Cheng J

更新日期：2015-04-21 00:00:00

abstract：AIM:To explore a safe and efficient strategy of tumor therapy using anti-angiogenetic agents. METHODS:Endostatin gene with a signal sequence of human IgGgamma chain was amplified by PCR and cloned into pVAX1 plasmid which was the only vector authorized by FDA in clinical trial to construct a recombinant plasmid named ...

journal_title：World journal of gastroenterology

authors： Ma CH,Zhang Y,Wang XY,Gao LF,Liu H,Guo C,Liu SX,Cao YL,Zhang LN,Sun WS

更新日期：2004-10-01 00:00:00

abstract：:Rescue antiviral treatment for patients with resistance to preexisting nucleos(t)ide analogues remains a clinical challenge. The correct choice of a first-line treatment of high potency and with a high genetic barrier to achieve sustained long-term suppression of viral replication provides the best chance of preventin...

journal_title：World journal of gastroenterology

authors： Bang KB,Kim HJ

更新日期：2014-09-07 00:00:00

abstract：BACKGROUND:Increasing levels of antibiotic resistance have reduced the Helicobacter pylori (H. pylori) eradication rates afforded by the standard triple therapy. Thus, 2-wk first-line four-drug regimens must be considered. AIM:To analyze the eradication rates of modified bismuth-containing quadruple therapy (mBCQT) an...

journal_title：World journal of gastroenterology

authors： Kim SJ,Chung JW,Woo HS,Kim SY,Kim JH,Kim YJ,Kim KO,Kwon KA,Park DK

更新日期：2019-12-14 00:00:00

abstract：:Inflammatory bowel disease (IBD) is associated with increased risk of colorectal cancer (CRC). The risk is known to increase with longer duration of the disease, family history of CRC, and history of primary sclerosing cholangitis. The diagnosis of the neoplastic changes associated with IBD is difficult owing to the h...

journal_title：World journal of gastroenterology

authors： Althumairi AA,Lazarev MG,Gearhart SL

更新日期：2016-01-21 00:00:00

abstract：AIM:To investigate whether Dihydromyricetin (DHM) inhibits cell proliferation and promotes apoptosis by downregulating Notch1 expression. METHODS:The correlation between Notch1 and Hes1 (a Notch1 target molecule) expression in hepatoma samples was confirmed by qRT-PCR. In addition, MTT assays, flow cytometry and TUNEL...

journal_title：World journal of gastroenterology

authors： Lu CJ,He YF,Yuan WZ,Xiang LJ,Zhang J,Liang YR,Duan J,He YH,Li MY

更新日期：2017-09-14 00:00:00

abstract：:Patients with inflammatory bowel disease are known to have a high demand of recurrent evaluation for therapy and disease activity. Further, the risk of developing cancer during the disease progression is increasing from year to year. New, mostly non-radiant, quick to perform and quantitative methods are challenging, c...

journal_title：World journal of gastroenterology

authors： Knieling F,Waldner MJ

更新日期：2016-07-07 00:00:00

abstract：AIM:To analyze the differences of clinical characteristics of colorectal neoplasm including polyps between the elderly and young Thai patients. METHODS:Colonoscopy database from December 2000 to October 2004 was retrospectively analyzed. There were 1822 eligible patients who underwent colonoscopy (with a mean age of 5...

journal_title：World journal of gastroenterology

authors： Rerknimitr R,Ratanapanich W,Kongkam P,Kullavanijaya P

更新日期：2006-12-21 00:00:00

abstract：AIM:To test the effect of the dephytinization of three different commercial infant cereals on iron, calcium, and zinc bioavailability by estimating the uptake, retention, and transport by Caco-2 cells. METHODS:Both dephytinized (by adding an exogenous phytase) and non-dephytinized infant cereals were digested using an...

journal_title：World journal of gastroenterology

authors： Frontela C,Scarino ML,Ferruzza S,Ros G,Martínez C

更新日期：2009-04-28 00:00:00

abstract：AIM:To highlight magnetic resonance enterography (MRE) for diagnosis of patients with refractory iron deficiency anemia and normal endoscopy results. METHODS:Fifty-three patients diagnosed with iron deficiency anemia refractory to treatment and normal gastroscopy and colonoscopy results were admitted to this prospecti...

journal_title：World journal of gastroenterology

authors： Cengic I,Tureli D,Aydin H,Bugdayci O,Imeryuz N,Tuney D

更新日期：2014-10-14 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver. It is the second leading cause of cancer-related deaths worldwide, with a very poor prognosis. In the United States, there has been only minimal improvement in the prognosis for HCC patients over the past 15 years. Details of the molecu...

journal_title：World journal of gastroenterology

authors： Ogunwobi OO,Harricharran T,Huaman J,Galuza A,Odumuwagun O,Tan Y,Ma GX,Nguyen MT

更新日期：2019-05-21 00:00:00

abstract：:The liver is the commonest site of distant metastasis of colorectal cancer and nearly half of the patients with colorectal cancer ultimately develop liver involved during the course of their diseases. Surgery is the only therapy that offers the possibility of cure for patients with hepatic metastatic diseases. Five-ye...

journal_title：World journal of gastroenterology

authors： Liu LX,Zhang WH,Jiang HC

更新日期：2003-02-01 00:00:00

abstract：:AIM:To investigate the incidence and management of nutritional deficiencies following a gastrectomy.METHODS:A gastrectomy population of 227 patients in London was followed up for 30 years after operation to detect and treat nutritional deficiencies.RESULTS:By the end of the first decade iron deficiency was the commone...

journal_title：World journal of gastroenterology

authors： Tovey FI,Hobsley M

更新日期：2000-02-01 00:00:00

abstract：AIM:Trace elements (TE) metabolism is altered in inflammatory bowel diseases. TE (zinc and copper) are constituents of antioxidant enzymes. Iron is involved in the pathogenesis of chronic inflammation. The aim was to evaluate zinc and copper status and the effects of iron manipulation in experimental colitis. METHODS:...

journal_title：World journal of gastroenterology

authors： Barollo M,D'Inca R,Scarpa M,Medici V,Cardin R,Bortolami M,Ruffolo C,Angriman I,Sturniolo GC

更新日期：2005-07-28 00:00:00

abstract：:Liver cancer is one of the world's most common cancers and the second leading cause of cancer deaths. Hepatocellular carcinoma (HCC), a primary hepatic cancer, accounts for 90%-95% of liver cancer cases. The pathogenesis of HCC consists of a stepwise process of liver damage that extends over decades, due to hepatitis,...

journal_title：World journal of gastroenterology

authors： Lu JW,Ho YJ,Yang YJ,Liao HA,Ciou SC,Lin LI,Ou DL

更新日期：2015-11-14 00:00:00

abstract：AIM:To identify risk factors to help predict which patients are likely to fail to appear for an endoscopic procedure. METHODS:This was a retrospective, chart review, cohort study in a Canadian, tertiary care, academic, hospital-based endoscopy clinic. Patients included were: those undergoing esophagogastroduodenoscopy...

journal_title：World journal of gastroenterology

authors： Wong VK,Zhang HB,Enns R

更新日期：2009-06-21 00:00:00

abstract：AIM:To examine the effect of Fusobacterium nucleatum (F. nucleatum) on the microenvironment of colonic neoplasms and the expression of inflammatory mediators and microRNAs (miRNAs). METHODS:Levels of F. nucleatum DNA, cytokine gene mRNA (TLR2, TLR4, NFKB1, TNF, IL1B, IL6 and IL8), and potentially interacting miRNAs (m...

journal_title：World journal of gastroenterology

authors： Proença MA,Biselli JM,Succi M,Severino FE,Berardinelli GN,Caetano A,Reis RM,Hughes DJ,Silva AE

更新日期：2018-12-21 00:00:00

abstract：AIM:To investigate whether composite yogurt with acacia dietary fiber and Bifidobacterium lactis (B. lactis) has additive effects in irritable bowel syndrome (IBS). METHODS:A total of 130 patients were randomly allocated to consume, twice daily for 8 wk, either the composite yogurt or the control product. The composit...

journal_title：World journal of gastroenterology

authors： Min YW,Park SU,Jang YS,Kim YH,Rhee PL,Ko SH,Joo N,Kim SI,Kim CH,Chang DK

更新日期：2012-09-07 00:00:00

abstract：:Alterations of normal function of interstitial cells of Cajal (ICC) are reported in many intestinal disorders. Diagnosis of their involvement is rare (infrequent), but necessary to propose a specific treatment. This article reviews the place of ICC in the pathogenesis of achalasia, gastroesophageal reflux disease, inf...

journal_title：World journal of gastroenterology

authors： Negreanu LM,Assor P,Mateescu B,Cirstoiu C

更新日期：2008-11-07 00:00:00

abstract：AIM:To investigate and elucidate the molecular mechanism that regulates inducible expression of CD69 by Helicobacter pylori (H. pylori) infection. METHODS:The expression levels of CD69 in a T-cell line, Jurkat, primary human peripheral blood mononuclear cells (PBMCs), and CD4+ T cells, were assessed by immunohistochem...

journal_title：World journal of gastroenterology

authors： Mori N,Ishikawa C,Senba M

更新日期：2011-08-28 00:00:00

abstract：AIM:To explore the relation between heparanase (HPA) and nm23-H1 in hepatocellular carcinoma (HCC), and whether they could be used as valuable markers in predicting post-operative metastasis and recurrence of HCC. METHODS:Reverse transcription-polymerase chain reaction and immunohistochemistry (S-P method) were used t...

journal_title：World journal of gastroenterology

authors： Liu YB,Gao SL,Chen XP,Peng SY,Fang HQ,Wu YL,Peng CH,Tang Z,Xu B,Wang JW,Deng GL,Li HJ,Feng XD,Qian HR

更新日期：2005-03-07 00:00:00

abstract：AIM:To explore the relationship of clinicopathological features and the distribution of neutrophils in the tumor microenvironment with the prognosis of cholangiocarcinoma. METHODS:Two hundred and fifty-four formalin-fixed and paraffin embedded tissue blocks were analyzed, including tissues from cholangiocarcinoma (n =...

journal_title：World journal of gastroenterology

authors： Mao ZY,Zhu GQ,Xiong M,Ren L,Bai L

更新日期：2015-04-28 00:00:00

abstract：AIM:To identify predictors for synchronous liver metastasis from resectable pancreatic ductal adenocarcinoma (PDAC) and assess unresectability of synchronous liver metastasis. METHODS:Retrospective records of PDAC patients with synchronous liver metastasis who underwent simultaneous resections of primary PDAC and sync...

journal_title：World journal of gastroenterology

authors： Shi HJ,Jin C,Fu DL

更新日期：2016-12-07 00:00:00

abstract：BACKGROUND:In recent decades, an increasing number of patients have received minimally invasive intervention for infected pancreatic necrosis (IPN) because of the benefits in reducing postoperative multiple organ failure and mortality. However, there are limited published data regarding infection recurrence after treat...

journal_title：World journal of gastroenterology

authors： Gao CC,Li J,Cao F,Wang XH,Li A,Wang Z,Li F

更新日期：2020-06-14 00:00:00

abstract：AIM:To explore the diffusion gradient b-factor that optimizes both apparent diffusion coefficient (ADC) measurement and contrast-to-noise (CNR) for assessing tumor response to transarterial chemoembolization (TACE) in a rabbit model. METHODS:Twelve New Zealand white rabbits bearing VX2 tumors in the liver were treated...

journal_title：World journal of gastroenterology

authors： Jiang ZX,Peng WJ,Li WT,Tang F,Liu SY,Qu XD,Wang JH,Lu HF

更新日期：2008-10-14 00:00:00

abstract：AIM:To evaluate the expressions of apoptotic signal proteins FADD, TRADD, FasL, Fas, and NFkappaB in gastric carcinoma tissues and their clinical significance. METHODS:Western blot immune trace method was adopted to detect the expressions of apoptotic signal proteins FADD, TRADD, FasL, Fas, and NFkappaB in 55 tissue s...

journal_title：World journal of gastroenterology

authors： Zhao XH,Gu SZ,Tian HG,Quan P,Pan BR

更新日期：2005-07-07 00:00:00