Etiopathogenesis of primary biliary cirrhosis.

abstract：:We report a case of a 32-year-old woman with episodic right lower quadrant abdominal pain. With the diagnosis of either acute appendicitis or tubo-ovarian abscess, she was treated with antibiotics, which successfully relieved the pain and the inflammatory findings. She repeated the clinical condition a few times and a...

journal_title：World journal of gastroenterology

authors： Niwa H,Hiramatsu T

更新日期：2008-02-28 00:00:00

abstract：:Colonic perforation during endoscopic diagnostic or therapeutic procedures, represents an uncommon occurrence even if, together with haemorrhage, it is still the most common complication of colonoscopy, with an incidence ranging between 0.1% and 2% of all colonoscopic procedures. The ideal treatment in these cases rem...

journal_title：World journal of gastroenterology

authors： Barbagallo F,Castello G,Latteri S,Grasso E,Gagliardo S,La Greca G,Di Blasi M

更新日期：2007-05-28 00:00:00

abstract：AIM:To identify the scFv antibody fragments specific for hepatocellular carcinoma by biopanning from a large human naive scFv phage display library. METHODS:A large human naive scFv phage library was used to search for the specific targets by biopanning with the hepatocellular carcinoma cell line HepG2 for the positiv...

journal_title：World journal of gastroenterology

authors： Yu B,Ni M,Li WH,Lei P,Xing W,Xiao DW,Huang Y,Tang ZJ,Zhu HF,Shen GX

更新日期：2005-07-14 00:00:00

abstract：AIM:To investigate the relationship between glucose metabolism and glypican-3 (GPC3) expression in hepatocellular carcinoma (HCC). METHODS:Immunohistochemical staining of pathological samples for GPC3 and glucose transporter 1 (GLUT1), and whole-body 18F-FDG PET/CT for measuring tumour glucose uptake were performed in...

journal_title：World journal of gastroenterology

authors： Li YC,Yang CS,Zhou WL,Li HS,Han YJ,Wang QS,Wu HB

更新日期：2018-01-28 00:00:00

abstract：:Alcoholic patients have a high incidence of hepatitis C virus (HCV) infection. Alcohol consumption enhances the severity of the HCV disease course and worsens the outcome of chronic hepatitis C. The accumulation of virally infected cells in the liver is related to the HCV-induced inability of the immune system to reco...

journal_title：World journal of gastroenterology

authors： Osna NA

更新日期：2009-03-14 00:00:00

abstract：:Viable and non-viable pathological bacterial translocation promote a self-perpetuating circle of dysfunctional immune activation and systemic inflammation facilitating infections and organ failure in advanced cirrhosis. Bacterial infections and sepsis are now recognized as a distinct stage in the natural progression o...

journal_title：World journal of gastroenterology

authors： Bruns T,Zimmermann HW,Stallmach A

更新日期：2014-03-14 00:00:00

abstract：:AIM:To determine whether recombinant human epidermal growth factor (rhEGF) can protect gastric mucosa against ethanol induced injury in rats.METHOD: Fifty-four SD rats weighing 200g-500g each were divided into six groups after fasting for 24 hours.Three groups received different doses of oral rhEGF (30, 60 and 120&mgr...

journal_title：World journal of gastroenterology

authors： Xu CD,Gan RB,Chen SN,Jiang SH,Xu JY

更新日期：1998-10-01 00:00:00

abstract：AIM:To investigate the changes of gut microflora and endotoxin levels in rats with acute liver failure (ALF) induced by D-galactosamine (GalN). METHODS:Flora and endotoxin levels in the jejunum, ileum and colon in normal rats (group A) and rats with GalN -induced ALF were determined at 24 h (group B) or 48 h (group C)...

journal_title：World journal of gastroenterology

authors： Li LJ,Wu ZW,Xiao DS,Sheng JF

更新日期：2004-07-15 00:00:00

abstract：AIM:To compare biofeedback-guided pelvic floor exercise therapy (BFT) with the use of oral polyethylene glycol (PEG) for the treatment of obstructive defecation. METHODS:A total of 88 subjects were assigned to treatment with either BFT (n = 44) or oral PEG (n = 44). Constipation symptoms (including difficult evacuatio...

journal_title：World journal of gastroenterology

authors： Ba-Bai-Ke-Re MM,Wen NR,Hu YL,Zhao L,Tuxun T,Husaiyin A,Sailai Y,Abulimiti A,Wang YH,Yang P

更新日期：2014-07-21 00:00:00

abstract：:The limited efficacy of cytotoxic therapy for advanced biliary tract and gallbladder cancers emphasizes the need for novel and more effective medical treatment options. A better understanding of the specific biological features of these neoplasms led to the development of new targeted therapies, which take the abundan...

journal_title：World journal of gastroenterology

authors： Hopfner M,Schuppan D,Scherubl H

更新日期：2008-12-14 00:00:00

abstract：AIM:To study the nuclear microsatellite instability (nMSI) at BAT26 and mitochondrial microsatellite instability (mtMSI) in the occurrence and development of hepatocellular carcinoma and the relationship between nMSI and mtMSI. METHODS:nMSI was observed with PCR and mtMSI with PCR-SSCP in 52 cases of hepatocellular ca...

journal_title：World journal of gastroenterology

authors： Fang DC,Fang L,Wang RQ,Yang SM

更新日期：2004-02-01 00:00:00

abstract：AIM:To study the inhibitory effects of a Shuangling Fuzheng anticancer preparation (SFAP) on the human gastric cancer cell line SGC-7901 in vitro as well as its immune-modulated effects in a cyclophosphamide-treated murine model. METHODS:MTT experiments and immunocytochemistry ABC experiments were performed for detect...

journal_title：World journal of gastroenterology

authors： Chen HS,Chen J,Cui DL,Zheng YY,Xu AH,Chen G,Jia LC

更新日期：2007-12-28 00:00:00

abstract：:The coexistence of hepatocellular carcinoma (HCC) and non-Hodgkin's lymphoma (NHL) in the liver is rare. Reports show that these patients have cirrhotic livers or hepatitis virus infections before they develop HCC and NHL. We present a patient with hepatitis B virus infection who was transferred to our hospital with a...

journal_title：World journal of gastroenterology

authors： Lee MH,Lin YC,Cheng HT,Chuang WY,Huang HC,Kao HW

更新日期：2015-12-07 00:00:00

abstract：AIM:To understand CD133 promoter hypermethylation and expression in 32 colorectal cancer cell lines. METHODS:Nucleic acid was isolated from 32 colorectal cancer cell lines and CD133 expression levels were measured by reverse transcription-polymerase chain reaction (RT-PCR) and real-time PCR. Promoter methylation statu...

journal_title：World journal of gastroenterology

authors： Jeon YK,Kim SH,Choi SH,Kim KH,Yoo BC,Ku JL,Park JG

更新日期：2010-07-07 00:00:00

abstract：AIM:To analyze the Hepatitis C virus (HCV) genotype distribution and transmission risk factors in a population of unselected patients in Luxembourg. METHODS:Epidemiological information (gender, age and transmission risks) were collected from 802 patients newly diagnosed for hepatitis C and living in Luxembourg, among ...

journal_title：World journal of gastroenterology

authors： Roman F,Hawotte K,Struck D,Ternes AM,Servais JY,Arendt V,Hoffman P,Hemmer R,Staub T,Seguin-Devaux C,Schmit JC

更新日期：2008-02-28 00:00:00

abstract：AIM:To evaluate the efficacy and safety of traditional Chinese surgical treatment for anal fistulae with secondary tracks and abscess. METHODS:Sixty patients with intersphincteric or transsphincteric anal fistulas with secondary tracks and abscess were randomly divided into study group [suture dragging combined with p...

journal_title：World journal of gastroenterology

authors： Wang C,Lu JG,Cao YQ,Yao YB,Guo XT,Yin HQ

更新日期：2012-10-28 00:00:00

abstract：AIM:To investigate the mechanisms of anti-liver fibrosis actions of Fuzheng Huayu (FZHY) decoction, which acts to strengthen the body's resistance and promote blood circulation. METHODS:Ito cells were isolated from rats and cultured. Serum samples were collected from healthy (normal) rats after administration of FZHY ...

journal_title：World journal of gastroenterology

authors： Liu CH,Liu C,Liu P,Xu LM

更新日期：1997-12-15 00:00:00

abstract：:We report a patient with HBV-related hepatocellular carcinoma (HCC) and refractory ascites who had received a peritoneal-venous shunt (PVS) 1 year before liver transplantation. Urgent surgical intervention following bowel obstruction and failure of immunosuppression therapy. No intestinal obstruction was found during ...

journal_title：World journal of gastroenterology

authors： Lin CH,Yu JC,Chen TW,Chan DC,Chen CJ,Hsieh CB

更新日期：2005-09-14 00:00:00

abstract：AIM:To study the differential protein profile in serum of hepatitis B patients. METHODS:Serum samples were obtained from patients with chronic hepatitis B who were receiving peginterferon alfa-2b. The serum samples were subjected to albumin depletion and analyzed by two-dimensional gel electrophoresis (2-DE). Differen...

journal_title：World journal of gastroenterology

authors： Kuakarn S,SomParn P,Tangkijvanich P,Mahachai V,Thongboonkerd V,Hirankarn N

更新日期：2013-08-21 00:00:00

abstract：AIM:To discuss the rationality of extended radical resection (ERR) and to guide the surgical treatment of rectal cancer. METHODS:Total 211 patients who underwent ERR from 1981 to 1987 (follow-up rate of 94.8 %) were selected to study the patterns of lymphatic metastasis and therapeutic effect. The control group was ma...

journal_title：World journal of gastroenterology

authors： Dong XS,Xu HT,Yu ZW,Liu M,Cu BB,Zhao P,Wang XS

更新日期：2003-05-01 00:00:00

abstract：AIM:To determine the expression of c-fos in gastric myenteric plexus and spinal cord of rats with cervical spondylosis and its clinical significance. METHODS:A cervical spondylosis model was established in rats by destroying the stability of cervical posterior column, and the cord segments C(4-6) and gastric antrum we...

journal_title：World journal of gastroenterology

authors： Song PS,Kong KM,Niu CY,Qi WL,Wu LF,Wang XJ,Han W,Huang K,Chen ZF

更新日期：2005-01-28 00:00:00

abstract：AIM:To compare the performance of the Da-an real-time hepatitis B virus (HBV) DNA assay and Abbott RealTime HBV assay. METHODS:HBV DNA standards as well as a total of 180 clinical serum samples from patients with chronic hepatitis B were measured using the Abbott and Da-an real-time polymerase chain reaction (PCR) ass...

journal_title：World journal of gastroenterology

authors： Qiu N,Li R,Yu JG,Yang W,Zhang W,An Y,Li T,Liu XE,Zhuang H

更新日期：2014-09-07 00:00:00

abstract：AIM:To study the practical use of the model for end-stage liver disease (MELD) on clinic and assess its validity by the concordance (C)-statistic in predicting the prognosis of the patient with severe viral hepatitis. METHODS:One hundred and twenty-one patients were divided into plasma exchange group and non-plasma ex...

journal_title：World journal of gastroenterology

authors： Weng ZH,Cai SQ

更新日期：2005-02-14 00:00:00

abstract：:The treatment of alcoholic hepatitis remains one of the most debated topics in medicine and a field of continued research. In this review, we discuss the evolution of scoring systems, including the recent development of the Glasgow alcoholic hepatitis score, role of liver biopsy and current treatment interventions. St...

journal_title：World journal of gastroenterology

authors： Rongey C,Kaplowitz N

更新日期：2006-11-21 00:00:00

abstract：:This article is to offer a concise review on the use of cytoreductive surgery (CRS) plus intraperitoneal hyperthermic chemotherapy (IPHC) for the treatment of peritoneal carcinomatosis (PC). Traditionally, PC was treated with systemic chemotherapy alone with very poor response and a median survival of less than 6 mo. ...

journal_title：World journal of gastroenterology

authors： Al-Shammaa HA,Li Y,Yonemura Y

更新日期：2008-02-28 00:00:00

abstract：AIM:To investigate whether butyrate or glutamine enemas could diminish inflammation in experimental diversion colitis. METHODS:Wistar specific pathogen-free rats were submitted to a Hartmann's end colostomy and treated with enemas containing glutamine, butyrate, or saline. Enemas were administered twice a week in the ...

journal_title：World journal of gastroenterology

authors： Pacheco RG,Esposito CC,Müller LC,Castelo-Branco MT,Quintella LP,Chagas VL,de Souza HS,Schanaider A

更新日期：2012-08-28 00:00:00

abstract：AIM:To study the hemodynamics in the immediate post transplant period and compare patients with alcoholic vs viral cirrhosis. METHODS:Between 2000-2003, 38 patients were transplanted for alcoholic cirrhosis and 28 for postviral cirrhosis. Heart rate (HR), central venous pressure (CVP), mean arterial pressure (MAP), pu...

journal_title：World journal of gastroenterology

authors： Al-Hamoudi WK,Alqahtani S,Tandon P,Ma M,Lee SS

更新日期：2010-02-07 00:00:00

abstract：:Alterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. Many studies have identified a large number of upregulated oncogenic miRNAs and downregulated tumour-suppressor miRNAs in this type of cancer. In this review, we provide an overview of the role of mi...

journal_title：World journal of gastroenterology

authors： da Silva Oliveira KC,Thomaz Araújo TM,Albuquerque CI,Barata GA,Gigek CO,Leal MF,Wisnieski F,Rodrigues Mello Junior FA,Khayat AS,de Assumpção PP,Rodriguez Burbano RM,Smith MC,Calcagno DQ

更新日期：2016-09-21 00:00:00

abstract：AIM:To investigate the effect of epidural anaesthesia (EA) on pancreatic microcirculation during acute pancreatitis (AP). METHODS:AP was induced by injection of sodium taurocholate into the pancreatic duct of Sprague-Dawley rats. To realize EA, a catheter was introduced into the epidural space between T7 and T9 and bu...

journal_title：World journal of gastroenterology

authors： Demirag A,Pastor CM,Morel P,Jean-Christophe C,Sielenkämper AW,Güvener N,Mai G,Berney T,Frossard JL,Bühler LH

更新日期：2006-02-14 00:00:00

abstract：AIM:To investigate the association of nuclear morphometry and DNA content with resectability of pancreatic cancer. METHODS:A total of 36 patients with pancreatic adenocarcinoma were divided into resectable group and unresectable group. The nuclear morphometry and DNA contents of tumor cells were analyzed by IBAS autoi...

journal_title：World journal of gastroenterology

authors： He YC,Peng W,Qiao JG,Cao J,Chen JW

更新日期：2003-08-01 00:00:00