Traditional Chinese surgical treatment for anal fistulae with secondary tracks and abscess.

Abstract:

AIM:To evaluate the efficacy and safety of traditional Chinese surgical treatment for anal fistulae with secondary tracks and abscess. METHODS:Sixty patients with intersphincteric or transsphincteric anal fistulas with secondary tracks and abscess were randomly divided into study group [suture dragging combined with pad compression (SDPC)] and control group [fistulotomy (FSLT)]. In the SDPC group, the internal opening was excised and incisions at external openings were made for drainage. Silk sutures were put through every two incisions and knotted in loose state. The suture dragging process started from the first day after surgery and the pad compression process started when all sutures were removed as wound tissue became fresh and without discharge. In the FSLT group, the internal opening and all tracts were laid open and cleaned by normal saline postoperatively till all wounds healed. The time of healing, postoperative pain score (visual analogue scale), recurrence rate, patient satisfaction, incontinence evaluation and anorectal manometry before and after the treatment were examined. RESULTS:There were no significant differences between the two groups regarding age, gender and fistulae type. The time of healing was significantly shorter (24.33 d in SDPC vs 31.57 d in FSLT, P < 0.01) and the patient satisfaction score at 1 mo postoperative follow-up was significantly higher in the SDPC group (4.07 in SDPC vs 3.37 in FSLT, P < 0.05). The mean maximal postoperative pain scores were 5.83 ± 2.5 in SDPC vs 6.37 ± 2.33 in FSLT and the recurrence rates were 3.33 in SDPC vs 0 in FSLT. None of the patients in the two groups experienced liquid and solid fecal incontinence and lifestyle alteration postoperatively. The Wexner score after treatment of intersphincter fistulae were 0.17 ± 0.41 in SDPC vs 0.40 ± 0.89 in FSLT and trans-sphincter fistulae were 0.13 ± 0.45 in SDPC vs 0.56 ± 1.35 in FSLT. The maximal squeeze pressure and resting pressure declined after treatment in both groups. The maximal anal squeeze pressures after treatment were reduced (23.17 ± 3.73 Kpa in SDPC vs 22.74 ± 4.47 Kpa in FSLT) and so did the resting pressures (12.36 ± 2.15 Kpa in SDPC vs 11.71 ± 1.87 Kpa in FSLT), but there were neither significant differences between the two groups and nor significant differences before or after treatment. CONCLUSION:Traditional Chinese surgical treatment SDPC for anal fistulae with secondary tracks and abscess is safe, effective and less invasive.

journal_name

World J Gastroenterol

authors

Wang C,Lu JG,Cao YQ,Yao YB,Guo XT,Yin HQ

doi

10.3748/wjg.v18.i40.5702

subject

Has Abstract

pub_date

2012-10-28 00:00:00

pages

5702-8

issue

40

eissn

1007-9327

issn

2219-2840

journal_volume

18

pub_type

杂志文章,随机对照试验
  • Perivascular epithelioid cell tumour of the liver.

    abstract::Perivascular epithelioid cell tumour is not uncommon in the liver but seldom malignant. ...

    journal_title:World journal of gastroenterology

    pub_type: 评论,信件

    doi:10.3748/wjg.14.3105

    authors: Stenram U

    更新日期:2008-05-21 00:00:00

  • Mechanisms of resistance to anti-EGFR monoclonal antibody treatment in metastatic colorectal cancer.

    abstract::Metastatic colorectal cancer (mCRC) continues to be counted as a major health problem. The introduction of newer cytotoxics, irinotecan and oxaliplatin, has achieved a significant improvement in survival rates. Novel targeted therapies (bevacizumab, and cetuximab) in combination with most efficient chemotherapy regime...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v16.i10.1177

    authors: Saridaki Z,Georgoulias V,Souglakos J

    更新日期:2010-03-14 00:00:00

  • Cavernous hemangioma arising from the gastro-splenic ligament: a case report.

    abstract::We present a rare case of a 45-year-old woman who presented with epigastric pain associated with early satiety and weight loss. Imaging revealed a large intra-abdominal mass in the epigastrium. Despite intensive investigations, including ultrasound scanning, computed tomography, upper gastrointestinal endoscopy, and p...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.3831

    authors: Chin KF,Khair G,Babu PS,Morgan DR

    更新日期:2009-08-14 00:00:00

  • Multiple chronic non-specific ulcer of small intestine characterized by anemia and hypoalbuminemia.

    abstract::A female patient with anemia and hypoalbuminemia was admitted to our hospital due to an over 20-year history of recurrent dizziness, fatigue and ankle edema. She was diagnosed as multiple chronic non-specific ulcer of the small intestine characterized by non-specific histology and persistent gastrointestinal bleeding....

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i6.782

    authors: Chen Y,Ma WQ,Chen JM,Cai JT

    更新日期:2010-02-14 00:00:00

  • Prognostic significance of preoperative circulating vascular endothelial growth factor messenger RNA expression in resectable hepatocellular carcinoma: a prospective study.

    abstract:AIM:To investigate the prognostic value of vascular endothelial growth factor messenger RNA (VEGF mRNA) in the peripheral blood (PB) of patients with hepatocellular carcinoma (HCC) undergoing curative resection. METHODS:Using a reverse-transcription polymerase chain reaction (RT-PCR)-based assay, VEGF mRNA in the PB w...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i5.643

    authors: Jeng KS,Sheen IS,Wang YC,Gu SL,Chu CM,Shih SC,Wang PC,Chang WH,Wang HY

    更新日期:2004-03-01 00:00:00

  • Current treatment for colorectal liver metastases.

    abstract::Surgical resection offers the best opportunity for survival in patients with colorectal cancer metastatic to the liver, with five-year survival rates up to 58% in selected cases. However, only a minority are resectable at the time of diagnosis. Continuous research in this field aims at increasing the percentage of pat...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v17.i36.4067

    authors: Misiakos EP,Karidis NP,Kouraklis G

    更新日期:2011-09-28 00:00:00

  • Expression and purification of the complete PreS region of hepatitis B Virus.

    abstract:AIM:To express the complete PreS region of HBV in E.coli with good solubility and stability, and to establish an effective method for purification of the recombinant PreS protein. METHODS:The complete PreS region (PreS1 and PreS2) was fused into a series of tags including glutathione S-transferase (GST), dihydrofolate...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i20.3060

    authors: Deng Q,Kong YY,Xie YH,Wang Y

    更新日期:2005-05-28 00:00:00

  • Value of transient elastography for the prediction of variceal bleeding.

    abstract:AIM:To determine if liver stiffness (LS) measurements by means of transient elastography (TE) correlate with the presence of significant esophageal varices (EV) and if they can predict the occurrence of variceal bleeding. METHODS:We studied 1000 cases of liver cirrhosis divided into 2 groups: patients without EV or wi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i17.2206

    authors: Sporea I,Raţiu I,Sirli R,Popescu A,Bota S

    更新日期:2011-05-07 00:00:00

  • Relationship between bilirubin free radical and formation of pigment gallstone.

    abstract::In this paper, we summarize the main progresses made in our group in the field of the mechanism of pigment gallstone formation. It was found that after treatment with free radicals, bilirubin (BR) was changed into free radical itself, and a semiquinone free radical and a superoxide free radical bound with metal were r...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v8.i3.413

    authors: Liu XT,Hu J

    更新日期:2002-06-01 00:00:00

  • S100A4 silencing blocks invasive ability of esophageal squamous cell carcinoma cells.

    abstract:AIM:To investigate a potential role of S100A4 in esophagus squamous cell carcinoma metastasis (ESCCs). METHODS:Expression of S100A4 and E-cadherin were analyzed in frozen sections from ESCCs (metastasis, n = 28; non-metastasis, n = 20) by reverse transcription-polymerase chain reaction, quantitative polymerase chain r...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i9.915

    authors: Chen D,Zheng XF,Yang ZY,Liu DX,Zhang GY,Jiao XL,Zhao H

    更新日期:2012-03-07 00:00:00

  • Organoids of liver diseases: From bench to bedside.

    abstract::Understanding the occurrence, development, and treatment of liver diseases is the main goal of hepatopathology research. Liver diseases are not only diverse but also highly heterogeneous among individuals. At present, research on liver diseases is conducted mainly through cell culture, animal models, pathological spec...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v25.i16.1913

    authors: Wu LJ,Chen ZY,Wang Y,Zhao JG,Xie XZ,Chen G

    更新日期:2019-04-28 00:00:00

  • Expression of matrix metalloproteinases and tissue inhibitor metalloproteinases increases in X-irradiated rat ileum despite the disappearance of CD8a T cells.

    abstract:AIM:To investigate their expression and activity in the rat ileum after exposure to ionizing radiation along with that of the cellular effectors and molecular mediators involved in the regulation of MMPs. METHODS:Rats were exposed to a single 10-Gy dose of X-rays delivered to the abdomen. A combination of methods, suc...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i40.6312

    authors: Strup-Perrot C,Vozenin-Brotons MC,Vandamme M,Linard C,Mathé D

    更新日期:2005-10-28 00:00:00

  • MicroRNA profile in neosquamous esophageal mucosa following ablation of Barrett's esophagus.

    abstract:AIM:To investigate the microRNA expression profile in esophageal neosquamous epithelium from patients who had undergone ablation of Barrett's esophagus. METHODS:High throughput screening using TaqMan® Array Human MicroRNA quantitative PCR was used to determine expression levels of 754 microRNAs in distal esophageal mu...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i30.5508

    authors: Sreedharan L,Mayne GC,Watson DI,Bright T,Lord RV,Ansar A,Wang T,Kist J,Astill DS,Hussey DJ

    更新日期:2017-08-14 00:00:00

  • Adverse events with bismuth salts for Helicobacter pylori eradication: systematic review and meta-analysis.

    abstract:AIM:To assess the safety of bismuth used in Helicobacter pylori (H pylori) eradication therapy regimens. METHODS:We conducted a systematic review and meta-analysis. MEDLINE and EMBASE were searched (up to October 2007) to identify randomised controlled trials comparing bismuth with placebo or no treatment, or bismuth ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审

    doi:10.3748/wjg.14.7361

    authors: Ford AC,Malfertheiner P,Giguere M,Santana J,Khan M,Moayyedi P

    更新日期:2008-12-28 00:00:00

  • Alverine citrate induced acute hepatitis.

    abstract::Alverine citrate is a commonly used smooth muscle relaxant agent. A MEDLINE search on January 2004 revealed only 1 report implicating the hepatotoxicity of this agent. A 34-year-old woman was investigated because of the finding of elevated liver function tests on biochemical screening. Other etiologies of hepatitis we...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i15.2303

    authors: Arhan M,Koklu S,Koksal AS,Yolcu OF,Koruk S,Koruk I,Kayacetin E

    更新日期:2004-08-01 00:00:00

  • Sonographic fatty liver and hepatitis B virus carrier status: synergistic effect on liver damage in Taiwanese adults.

    abstract:AIM:To examine the epidemiology of hepatitis B virus carrier status (HBVC) and sonographic fatty liver (SFL) in Taiwanese adults, and to evaluate their possible interaction in inducing liver damage (LD). >From an epidemiological viewpoint, we analyzed previous studies which indicated that fatty liver sensitizes host im...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i12.1805

    authors: Lin YC,Hsiao ST,Chen JD

    更新日期:2007-03-28 00:00:00

  • MicroRNAs as therapeutic strategy for hepatitis B virus-associated hepatocellular carcinoma: current status and future prospects.

    abstract::Hepatocellular carcinoma (HCC) remains to be one of the top causing cancer-related deaths today. The majority of HCC cases are reported to be the result of chronic hepatitis B virus (HBV) infection. Current treatments for HBV-related HCC revolve around the use of drugs to inhibit viral replication, as a high level of ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i20.5973

    authors: Tan YL,Chen WN

    更新日期:2014-05-28 00:00:00

  • Clinical characteristics and prognostic factors of splenic abscess: a review of 67 cases in a single medical center of Taiwan.

    abstract:AIM:To analyze 67 cases of splenic abscess in a medical center of Taiwan during a period of 19 years. METHODS:From January 1986 to December 2004, a total of 67 patients with splenic abscess were enrolled for the retrospective study. The clinical characteristics, underlying diseases, organism spectra, therapeutic metho...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i3.460

    authors: Chang KC,Chuah SK,Changchien CS,Tsai TL,Lu SN,Chiu YC,Chen YS,Wang CC,Lin JW,Lee CM,Hu TH

    更新日期:2006-01-21 00:00:00

  • Hematologic manifestations of Helicobacter pylori infection.

    abstract::Helicobacter pylori (H. pylori) is the most common infection in humans, with a marked disparity between developed and developing countries. Although H. pylori infections are asymptomatic in most infected individuals, they are intimately related to malignant gastric conditions such as gastric cancer and gastric mucosa-...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i36.12818

    authors: Campuzano-Maya G

    更新日期:2014-09-28 00:00:00

  • 1,2,3,4,6-penta-O-galloyl-beta-D-glucose up-regulates heme oxygenase-1 expression by stimulating Nrf2 nuclear translocation in an extracellular signal-regulated kinase-dependent manner in HepG2 cells.

    abstract:AIM:To examine the potency of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) as a hepatic heme oxygenase-1 (HO-1) inducer and its regulation in HepG2 cells. METHODS:Expression of HO-1 and NF-E2-related factor 2 (Nrf2) and activation of mitogen-activated protein (MAP) kinases were analyzed by Western blot, immunofluore...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i2.214

    authors: Pae HO,Oh GS,Jeong SO,Jeong GS,Lee BS,Choi BM,Lee HS,Chung HT

    更新日期:2006-01-14 00:00:00

  • Diagnosis and treatment of iron-deficiency anemia in gastrointestinal bleeding: A systematic review.

    abstract:BACKGROUND:Anemia is considered a public health issue and is often caused by iron deficiency. Iron-deficiency anemia (IDA) often originates from blood loss from lesions in the gastrointestinal tract in men and postmenopausal women, and its prevalence among patients with gastrointestinal bleeding has been estimated to b...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v26.i45.7242

    authors: Cotter J,Baldaia C,Ferreira M,Macedo G,Pedroto I

    更新日期:2020-12-07 00:00:00

  • Enhanced electrogastrography: A realistic way to salvage a promise that was never kept?

    abstract:AIM:To enhance the clinical utility of electrogastrography (EGG), which has been recorded since 1922, but is clinically unutilized. METHODS:An innovative method to salvage the promise of EGG is proposed by introducing a preliminary procedure, while maintaining the electrodes, standardized equipment, and signal process...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i25.4517

    authors: Poscente MD,Mintchev MP

    更新日期:2017-07-07 00:00:00

  • Protective effect of melatonin against liver injury in mice induced by Bacillus Calmette-Guerin plus lipopolysaccharide.

    abstract:AIM:To investigate the effects and mechanisms of melatonin on immunological liver injury in mice. METHODS:A model of liver injury was induced by tail vein injection of Bacillus Calmette Guerin (BCG) and lipopolysaccharide (LPS) in mice. Kupffer cells and hepatocytes were isolated and cultured according to a modified t...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i18.2690

    authors: Wang H,Wei W,Shen YX,Dong C,Zhang LL,Wang NP,Yue L,Xu SY

    更新日期:2004-09-15 00:00:00

  • Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines.

    abstract:AIM:To investigate the growth inhibitory mechanism of four caged xanthones from Garcinia hanburyi in cholangiocarcinoma (CCA) KKU-100 and KKU-M156 cells. METHODS:Four caged xanthones, selected on the basis of their anticancer potency and chemical structure diversities (i.e. isomorellin, isomorellinol, forbesione and g...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i18.2235

    authors: Hahnvajanawong C,Boonyanugomol W,Nasomyon T,Loilome W,Namwat N,Anantachoke N,Tassaneeyakul W,Sripa B,Namwat W,Reutrakul V

    更新日期:2010-05-14 00:00:00

  • Cortactin expression confers a more malignant phenotype to gastric cancer SGC-7901 cells.

    abstract:AIM:To study the effects of cortactin on the tumor biology of SGC-7901 cells and identify the mechanism involved in the process. METHODS:Cell lines in which cortactin was stably overexpressed or knocked down as well as the respective control cell lines were established by standard molecular methods. The effects of cor...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i12.3287

    authors: Wei J,Zhao ZX,Li Y,Zhou ZQ,You TG

    更新日期:2014-03-28 00:00:00

  • How many cases of laryngopharyngeal reflux suspected by laryngoscopy are gastroesophageal reflux disease-related?

    abstract:AIM:To investigate the prevalence of gastroesophageal reflux disease (GERD) in patients with a laryngoscopic diagnosis of laryngopharyngeal reflux (LPR). METHODS:Between May 2011 and October 2011, 41 consecutive patients with laryngopharyngeal symptoms (LPS) and laryngoscopic diagnosis of LPR were empirically treated ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i32.4363

    authors: de Bortoli N,Nacci A,Savarino E,Martinucci I,Bellini M,Fattori B,Ceccarelli L,Costa F,Mumolo MG,Ricchiuti A,Savarino V,Berrettini S,Marchi S

    更新日期:2012-08-28 00:00:00

  • Huge undifferentiated carcinoma of the pancreas with osteoclast-like giant cells.

    abstract::Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells (OGCs) is very rare, less than 1% of all pancreatic malignancies, and shows worse prognosis than that of invasive ductal adenocarcinoma of the pancreas. We present a case of en bloc resection for a huge undifferentiated carcinoma with OGCs tha...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i10.2725

    authors: Jo S

    更新日期:2014-03-14 00:00:00

  • NOB1 is essential for the survival of RKO colorectal cancer cells.

    abstract:AIM:To determine the role of NOB1, a regulator of cell survival in yeast, in human colorectal cancer cells. METHODS:Lentivirus-mediated small interfering RNA (siRNA) was used to inhibit NOB1 expression in RKO human colorectal cancer cells in vitro and in vivo in a mouse xenograft model. The in vitro and in vivo knockd...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i3.868

    authors: He XW,Feng T,Yin QL,Jian YW,Liu T

    更新日期:2015-01-21 00:00:00

  • Patient-reported outcomes in subjects with neuroendocrine tumors of the pancreas.

    abstract:AIM:To assess the patient-reported outcomes (PROs) of pancreatic neuroendocrine tumor (PNET) patients. METHODS:Fifty-one consecutive patients (21 male, 30 female, 61.0 +/- 10.3 years) with proven PNETs were studied. An SF-12 questionnaire capable of exploring the physical (PCS) and mental (MCS) aspects of daily life w...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.5067

    authors: Pezzilli R,Campana D,Morselli-Labate AM,Fabbri MC,Brocchi E,Tomassetti P

    更新日期:2009-10-28 00:00:00

  • A review of Helicobacter pylori diagnosis, treatment, and methods to detect eradication.

    abstract::Helicobacter pylori (H. pylori) affects nearly half of the world's population and, thus, is one of the most frequent and persistent bacterial infections worldwide. H. pylori is associated with peptic ulcer disease, gastric ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer. Various diagnostic metho...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i6.1438

    authors: Garza-González E,Perez-Perez GI,Maldonado-Garza HJ,Bosques-Padilla FJ

    更新日期:2014-02-14 00:00:00