Cortactin expression confers a more malignant phenotype to gastric cancer SGC-7901 cells.

abstract：AIM:To investigate the accuracy of endoscopic or biopsy diagnoses of superficial nonampullary duodenal epithelial tumors (NADETs). METHODS:Clinicopathological data were reviewed for 84 superficial NADETs from 74 patients who underwent surgery or endoscopic resection between September 2002 and August 2014 at a single p...

journal_title：World journal of gastroenterology

authors： Kakushima N,Kanemoto H,Sasaki K,Kawata N,Tanaka M,Takizawa K,Imai K,Hotta K,Matsubayashi H,Ono H

更新日期：2015-05-14 00:00:00

abstract：AIM:To describe the imaging features of solitary fibrous tumors (SFTs) in the abdomen and pelvis, and the clinical and pathologic correlations. METHODS:Fifteen patients with pathologically confirmed SFTs in the abdomen and pelvis were retrospectively studied with imaging techniques by two radiologists in consensus. Pa...

journal_title：World journal of gastroenterology

authors： Li XM,Reng J,Zhou P,Cao Y,Cheng ZZ,Xiao Y,Xu GH

更新日期：2014-05-07 00:00:00

abstract：AIM:To investigate the inhibitory effect of in vivo expression of expressing plasmid pCH510 of recombinant fibronectin polypeptide (CH50) on hepatocellular carcinoma and the improved therapeutic effect of pCH510 in combination with chemotherapeutic agents and Hsp70-H22 hepatocarcinoma antigen peptide on tumor. METHODS...

journal_title：World journal of gastroenterology

authors： Zhang GM,Yang Y,Huang B,Xiao H,Li D,Feng ZH

更新日期：2003-09-01 00:00:00

abstract：AIM:To investigate the mucosal protective effect and the mechanisms of action of the anti-ulcer drug irsogladine maleate in gastric injury induced by indomethacin in rats. METHODS:Gastric mucosal injury was induced in male Hos:Donryu rats by oral administration of indomethacin at a dose of 48 mg/kg. One hour before in...

journal_title：World journal of gastroenterology

authors： Zhang X,Tajima K,Kageyama K,Kyoi T

更新日期：2008-08-14 00:00:00

abstract：AIM:To evaluate attenuating properties of N-acetylcysteine (NAC) on oxidative stress and liver pathology in rats with non-alcoholic steatohepatitis (NASH). METHODS:Male Sprague-Dawley rats were randomly divided into three groups. Group 1 (control, n=8) was free accessed to regular dry rat chow (RC) for 6 wk. Group 2 (...

journal_title：World journal of gastroenterology

authors： Thong-Ngam D,Samuhasaneeto S,Kulaputana O,Klaikeaw N

更新日期：2007-10-14 00:00:00

abstract：AIM:To evaluate different methods in differentiating idiopathic neonatal hepatitis from biliary atresia. METHODS:Sixty-five infants with cholestatic jaundice and final diagnosis of idiopathic neonatal hepatitis and biliary atresia were studied prospectively from September 2003 to March 2006. A thorough history and phy...

journal_title：World journal of gastroenterology

authors： Dehghani SM,Haghighat M,Imanieh MH,Geramizadeh B

更新日期：2006-09-28 00:00:00

abstract：AIM:To evaluate the utility of measuring epigenetic alterations in pancreatic and biliary fluids in determining molecular markers for pancreatobiliary cancers. METHODS:DNA was extracted from undiluted pancreatic and biliary fluids. As a surrogate for a genome-wide hypomethylation assay, levels of long interspersed nuc...

journal_title：World journal of gastroenterology

authors： Kato N,Yamamoto H,Adachi Y,Ohashi H,Taniguchi H,Suzuki H,Nakazawa M,Kaneto H,Sasaki S,Imai K,Shinomura Y

更新日期：2013-03-21 00:00:00

abstract：BACKGROUND:Understanding the treatment landscape of inflammatory bowel diseases (IBD) is essential for improving disease management and patient outcomes. Brazil is the largest Latin American country, and it presents socioeconomic and health care differences across its geographical regions. This country has the highest ...

journal_title：World journal of gastroenterology

authors： Zaltman C,Parra RS,Sassaki LY,Santana GO,Ferrari MLA,Miszputen SJ,Amarante HMBS,Kaiser Junior RL,Flores C,Catapani WR,Parente JML,Bafutto M,Ramos O,Gonçalves CD,Guimaraes IM,da Rocha JJR,Feitosa MR,Feres O,Saad-Hossne

更新日期：2021-01-14 00:00:00

abstract：AIM:To investigate the possible mechanism by which hepatitis B virus X protein (HBx) mediates apoptosis of HepG2 cells. METHODS:HBx expression vector pcDNA3.1-X was transfected into HepG2 cells to establish an HBx high-expression cellular model as pcDNA3.1-X transfected group. The pcDNA3.1-X and pSilencer3.1-shHBX (HB...

journal_title：World journal of gastroenterology

authors： Tang RX,Kong FY,Fan BF,Liu XM,You HJ,Zhang P,Zheng KY

更新日期：2012-04-07 00:00:00

abstract：AIM:To investigate expression of microRNA (miRNA) and potential targets in chemotherapy resistant esophageal cancer cell lines. METHODS:An in-vitro model of acquired chemotherapy resistance in esophageal adeno- (EAC) and squamous cell carcinoma (ESCC) cells was used, and microRNA expression profiles for cisplatin or 5...

journal_title：World journal of gastroenterology

authors： Hummel R,Sie C,Watson DI,Wang T,Ansar A,Michael MZ,Van der Hoek M,Haier J,Hussey DJ

更新日期：2014-10-28 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is a disease in which excessive fat accumulates in the liver of a patient without a history of alcohol abuse. This disease includes simple steatosis and nonalcoholic steatohepatitis (NASH). NAFLD/NASH is recognized as a hepatic manifestation of metabolic syndrome. In recent yea...

journal_title：World journal of gastroenterology

authors： Takahashi Y,Fukusato T

更新日期：2010-11-14 00:00:00

abstract：AIM:To investigate the association between cytokine gene polymorphism and disease status in chronic hepatitis C genotype 3 by liver biopsy, ALT, HCV RNA levels and response to treatment. METHODS:Patients with chronic hepatitis C genotype 3 were analyzed for single nucleotide polymorphisms of interleukin (IL)-10, IL-1 ...

journal_title：World journal of gastroenterology

authors： Abbas Z,Moatter T,Hussainy A,Jafri W

更新日期：2005-11-14 00:00:00

abstract：:To review the implication of CXCR4 for gastrointestinal cancer, a "Pubmed" analysis was performed in order to evaluate the relevance of CXCR4 and its ligands for gastrointestinal cancers. Search terms applied were "cancer, malignoma, esophageal, gastric, colon, colorectal, hepatic, pancreatic, CXCR4, SDF-1alpha, and S...

journal_title：World journal of gastroenterology

authors： Schimanski CC,Galle PR,Moehler M

更新日期：2008-08-14 00:00:00

abstract：:Acute acalculous cholecystitis (AAC) is defined as an acute inflammation of the gallbladder in the absence of stones. We herein report a case of a young man who developed AAC after a Salmonella enteritidis gastrointestinal infection. ...

journal_title：World journal of gastroenterology

authors： Ruiz-Rebollo ML,Sánchez-Antolín G,García-Pajares F,Vallecillo-Sande MA,Fernández-Orcajo P,Velicia-Llames R,Caro-Patón A

更新日期：2008-11-07 00:00:00

abstract：AIM:To evaluate the efficacy and the safety of combined 5-Fluorouracil, irinotecan, bevacizumab and sirolimus in refractory advanced colorectal carcinoma. METHODS:We initiated a regimen with at day 1 an injection (iv) of bevacizumab at 5 mg/kg, followed by 180 mg/m(2) irinotecan, followed by Leucovorin 400 mg/m(2), fo...

journal_title：World journal of gastroenterology

authors： Ghiringhelli F,Guiu B,Chauffert B,Ladoire S

更新日期：2009-09-14 00:00:00

abstract：:Cyclophosphamide is a potent cytotoxic agent used in many clinical settings. The main risks of cyclophosphamide therapy include hematological disorders, infertility, hemorrhagic cystitis and malignancies. Gastrointestinal side effects reported to date are often non-specific and not severe. We present the first case of...

journal_title：World journal of gastroenterology

authors： Yang LS,Cameron K,Papaluca T,Basnayake C,Jackett L,McKelvie P,Goodman D,Demediuk B,Bell SJ,Thompson AJ

更新日期：2016-10-21 00:00:00

abstract：:Actinomycosis is a rare, chronic, spreading, suppurative, granulomatous and fibrosing infection. Actinomyces are normal inhabitants of the oral cavity and gastrointestinal tract. They rarely cause disease and are seldom reported as pathogens. Herein, we reported on a 69-year-old male patient who had undergone Whipple'...

journal_title：World journal of gastroenterology

authors： Hsu JT,Lo HC,Jan YY,Chen HM

更新日期：2005-03-21 00:00:00

abstract：AIM:To study the nuclear microsatellite instability (nMSI) at BAT26 and mitochondrial microsatellite instability (mtMSI) in the occurrence and development of hepatocellular carcinoma and the relationship between nMSI and mtMSI. METHODS:nMSI was observed with PCR and mtMSI with PCR-SSCP in 52 cases of hepatocellular ca...

journal_title：World journal of gastroenterology

authors： Fang DC,Fang L,Wang RQ,Yang SM

更新日期：2004-02-01 00:00:00

abstract：AIM:To identify the scFv antibody fragments specific for hepatocellular carcinoma by biopanning from a large human naive scFv phage display library. METHODS:A large human naive scFv phage library was used to search for the specific targets by biopanning with the hepatocellular carcinoma cell line HepG2 for the positiv...

journal_title：World journal of gastroenterology

authors： Yu B,Ni M,Li WH,Lei P,Xing W,Xiao DW,Huang Y,Tang ZJ,Zhu HF,Shen GX

更新日期：2005-07-14 00:00:00

abstract：:Crohn's disease is a chronic inflammatory granulomatous process that usually involves different sites in the intestinal tract. Genetic and environmental factors are thought to play a role in its etiology and pathogenesis. The disorder has a heterogeneous clinical expression and data from tertiary care settings have do...

journal_title：World journal of gastroenterology

authors： Freeman HJ

更新日期：2009-03-21 00:00:00

abstract：AIM:To identify preoperative predictive factors associated with malignancy of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. METHODS:Between April 1995 and April 2010, 129 patients underwent surgical resection for IPMNs at our institute and had confirmed pathologic diagnoses. The medical records wer...

journal_title：World journal of gastroenterology

authors： Lee JH,Lee KT,Park J,Bae SY,Lee KH,Lee JK,Jang KT,Heo JS,Choi SH,Choi DW,Rhee JC

更新日期：2010-11-14 00:00:00

abstract：:AIM:To evaluate a culture system for bile acid formation in primary human hepatocytes in comparison with HepG2 cells.METHODS:Hepatocytes were isolated from normal human liver tissue and we re cultured in serum-free William's E medium.The medium was collected and re newed every 24 h. Bile acids and their precursors in ...

journal_title：World journal of gastroenterology

authors： Einarsson C,Ellis E,Abrahamsson A,Ericzon BG,Bjorkhem I,Axelson M

更新日期：2000-08-01 00:00:00

abstract：AIM:To describe cases of gut perforation after orthotopic liver transplantation. METHODS:Data were collected from our center database and medical records. Six of 187 patients (3.2%) who underwent orthotopic liver transplantation from January to December 2005 developed gut perforation. All patients were male with an av...

journal_title：World journal of gastroenterology

authors： Xiong J,You S,He XS

更新日期：2007-04-14 00:00:00

abstract：:Unspecific abdominal complaints including bloating and irregular bowel movements may be caused by carbohydrate malabsorption syndromes, e.g., lactose and fructose malabsorption. These symptoms were investigated with hydrogen (H2) breath tests and correlated to carbohydrate malabsorption. During performing these H2-bre...

journal_title：World journal of gastroenterology

authors： Schnedl WJ,Kalmar P,Mangge H,Krause R,Wallner-Liebmann SJ

更新日期：2015-09-21 00:00:00

abstract：AIM:To evaluate the effects of betaine on the ethanol-induced secretion of IGF-I and IGFBP-1 using radioimmunoassay and Western blotting, respectively, in primary cultured rat hepatocytes. METHODS:Hepatocytes isolated from male Sprague-Dawley rats were incubated with various concentrations of ethanol and PD98059 proce...

journal_title：World journal of gastroenterology

authors： Lee MS,Kim MS,Park SY,Kang CW

更新日期：2006-03-21 00:00:00

abstract：AIM:To investigate the role of single nucleotide polymorphisms (SNPs) in CD24 gene in susceptibility and overall survival of gastric cancer (GC). METHODS:We genotyped 3 tagging SNPs of CD24-P-534 in the promoter region, P170 in the coding region of exon 2 and P1527 in the 3' untranslated region - using polymerase chai...

journal_title：World journal of gastroenterology

authors： Jia ZF,Wang LZ,Cao XY,Wang C,Cao DH,Wu X,You LL,Jin MS,Wang YP,Zhou BS,Jiang J

更新日期：2016-02-21 00:00:00

abstract：BACKGROUND:Epithelioid angiosarcoma is a vascular neoplasm that is among the most aggressive subtypes of sarcomas. Its involvement in the gastrointestinal tract is rare. We here report a case of multifocal gastrointestinal epithelioid angiosarcomas presenting with gastrointestinal bleeding. CASE SUMMARY:A 77-year-old ...

journal_title：World journal of gastroenterology

authors： Chen YW,Dong J,Chen WY,Dai YN

更新日期：2020-08-07 00:00:00

abstract：AIM:To evaluate the effects of DA-9701 on the gastric emptying of a solid meal using the ¹³C-octanoic acid breath test in a mouse model. METHODS:Male C57BL/6 mice aged > 8 wk and with body weights of 20-25 g were used in this study. The solid test meal consisted of 200 mg of egg yolk labeled with 1.5 L/g ¹³C-octanoic ...

journal_title：World journal of gastroenterology

authors： Lim CH,Choi MG,Park H,Baeg MK,Park JM

更新日期：2013-07-21 00:00:00

abstract：AIM:To review the cases reported in the literature, examined their clinicopathological features, and evaluated the efficacy of different therapeutic modalities for this rare condition. METHODS:A search of the MEDLINE database revealed 16 cases of pericarditis carcinomatosa (PC) originating from GC reported in the lite...

journal_title：World journal of gastroenterology

authors： Kobayashi M,Okabayashi T,Okamoto K,Namikawa T,Araki K

更新日期：2005-11-28 00:00:00

abstract：AIM:To clone and express the antigen of monoclonal antibody (MAb) PD4 for further investigation of its function. METHODS:MGC803 cDNA expression library was constructed and screened with PD4 as probes to clone the antigen. After failed in the library screening, immunoprecipitation and SDS-polyacrylamide gel electrophor...

journal_title：World journal of gastroenterology

authors： Ning JY,Sun GX,Huang S,Ma H,An P,Meng L,Song SM,Wu J,Shou CC

更新日期：2003-10-01 00:00:00