Effects of betaine on ethanol-stimulated secretion of IGF-I and IGFBP-1 in rat primary hepatocytes: involvement of p42/44 MAPK activation.

abstract：AIM:To evaluate the role of RARalpha gene in mediating the growth inhibitory effect of all-trans retinoic acid (ATRA) on gastric cancer cells. METHODS:The expression levels of retinoic acid receptors (RARs) in gastric cancer cells were detected by Northern blot. Transient transfection and chlorophenicol acetyl transfe...

journal_title：World journal of gastroenterology

authors： Liu S,Wu Q,Chen ZM,Su WJ

更新日期：2001-10-01 00:00:00

abstract：AIM:To evaluate clinical presentation, etiology, complications and response to treatment in elderly patients with acute cholangitis. METHODS:Demographics, etiology of biliary obstruction, clinical features, complications and associated systemic diseases of 175 patients with acute cholangitis were recorded. Endoscopic ...

journal_title：World journal of gastroenterology

authors： Agarwal N,Sharma BC,Sarin SK

更新日期：2006-10-28 00:00:00

abstract：AIM:To clone and express the antigen of monoclonal antibody (MAb) PD4 for further investigation of its function. METHODS:MGC803 cDNA expression library was constructed and screened with PD4 as probes to clone the antigen. After failed in the library screening, immunoprecipitation and SDS-polyacrylamide gel electrophor...

journal_title：World journal of gastroenterology

authors： Ning JY,Sun GX,Huang S,Ma H,An P,Meng L,Song SM,Wu J,Shou CC

更新日期：2003-10-01 00:00:00

abstract：:Cholelithiasis occurs infrequently in the paediatric age group. Hereditary spherocytosis, sickle cell anaemia and thalassemia are the haemolytic disorders most commonly associated with development of gall stones in paediatric age group. The question is whether an isolated episode of haemolysis can cause gallstones. ...

journal_title：World journal of gastroenterology

authors： Kejariwal D

更新日期：2006-04-14 00:00:00

abstract：:AIM:To discuss the effect of surgical procedures on the prognosis of patients of bile duct cancer and their indications.METHODS:A retrospective analysis was made for 52 cases of hepatoportal bile duct cancer treated from January 1991 to December 1996. All the cases were classified according to the modified Bismuth-Cor...

journal_title：World journal of gastroenterology

authors： He XS,Huang JF,Liang LJ,Lu MD,Cao XH

更新日期：1999-04-01 00:00:00

abstract：:Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. The identification of colonic polyps can reduce CRC mortality through earlier diagnosis of cancers and the removal of polyps: the precursor lesion of CRC. Following the finding and removal of colonic polyps at an initial colonoscopy, some p...

journal_title：World journal of gastroenterology

authors： Bonnington SN,Rutter MD

更新日期：2016-02-14 00:00:00

abstract：BACKGROUND:Extrahepatic metastasis (EHM) of hepatocellular carcinoma (HCC) is associated with poor outcomes. However, the clinical features and risk factors of EHM of HCC after radiofrequency ablation (RFA) remain unclear. AIM:To elucidate the characteristics and risk factors of EHM after RFA for HCC. METHODS:From Ja...

journal_title：World journal of gastroenterology

authors： Yoon JH,Goo YJ,Lim CJ,Choi SK,Cho SB,Shin SS,Jun CH

更新日期：2020-08-28 00:00:00

abstract：:Acute pancreatitis (AP) is an acute inflammatory disease of the exocrine pancreas. In Japan, nationwide epidemiological surveys have been conducted every 4 to 5 years by the Research Committee of Intractable Pancreatic Diseases, under the support of the Ministry of Health, Labour, and Welfare of Japan. We reviewed the...

journal_title：World journal of gastroenterology

authors： Hamada S,Masamune A,Shimosegawa T

更新日期：2016-07-28 00:00:00

abstract：BACKGROUND:Laparoscopy has been widely used in general surgical procedures, but total laparoscopic pancreaticoduodenectomy (TLPD) is still a complex and challenging surgery that is only performed in a small number of patients at a few large academic medical centers. Although the safety and feasibility of TLPD have been...

journal_title：World journal of gastroenterology

authors： Zhang H,Lan X,Peng B,Li B

更新日期：2019-10-07 00:00:00

abstract：AIM:To explore the quantitative analysis of diffusion-weighted magnetic resonance imaging (DWMRI) in differential diagnosis of focal hepatic lesions. METHODS:DWMRI was performed in 149 hepatic lesions, including hepatocellular carcinoma (34 cases), hepatic metastases (37 cases), cavernous hemangioma (42 cases), hepati...

journal_title：World journal of gastroenterology

authors： Sun XJ,Quan XY,Huang FH,Xu YK

更新日期：2005-11-07 00:00:00

abstract：AIM:To induce the tolerance of rat liver allograft by dendritic cells (DCs) modified with NF-kappaB decoy oligodeoxynucleotides (ODNs). METHODS:Bone marrow (BM)-derived DCs from SD rats were propagated in the presence of GM-CSF or GM-CSF+IL-4 to obtain immature DCs or mature DCs. GM-CSF+IL-4-propagated DCs were treate...

journal_title：World journal of gastroenterology

authors： Xu MQ,Suo YP,Gong JP,Zhang MM,Yan LN

更新日期：2004-08-15 00:00:00

abstract：:Colorectal cancer incidence and mortality in patients younger than 50 years are increasing, but screening before the age of 50 is not offered in Europe. Advanced-stage diagnosis and mortality from colorectal cancer before 50 years of age are increasing. This is not a detection-bias effect; it is a real issue affecting...

journal_title：World journal of gastroenterology

authors： Mannucci A,Zuppardo RA,Rosati R,Leo MD,Perea J,Cavestro GM

更新日期：2019-06-07 00:00:00

abstract：AIM:To investigate the biological function of complete S protein and to look for proteins interacting with complete S protein in hepatocytes. METHODS:We constructed bait plasmid expressing complete S protein of HBV by cloning the gene of complete S protein into pGBKT7, then the recombinant plasmid DNA was transformed ...

journal_title：World journal of gastroenterology

authors： Bai GQ,Cheng J,Zhang SL,Huang YP,Wang L,Liu Y,Lin SM

更新日期：2005-07-07 00:00:00

abstract：AIM:To evaluate the value of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) level for predicting postoperative atrial fibrillation (AF) in patients undergoing surgery for esophageal carcinoma. METHODS:NT-proBNP levels were measured in 142 patients 24 h before and 1 h after surgery for esophageal carcinoma...

journal_title：World journal of gastroenterology

authors： Hou JL,Gao K,Li M,Ma JY,Shi YK,Wang Y,Zhao YF

更新日期：2008-04-28 00:00:00

abstract：AIM:To explore recent trends, modes of diagnosis, ethnic distribution and the mortality to incidence ratio of primary liver cancer by subtypes in England and Wales. METHODS:We obtained incidence (1979-2008) and mortality (1968-2008) data for primary liver cancer for England and Wales and calculated age-standardised in...

journal_title：World journal of gastroenterology

authors： Ladep NG,Khan SA,Crossey MM,Thillainayagam AV,Taylor-Robinson SD,Toledano MB

更新日期：2014-02-14 00:00:00

abstract：:A 41-year-old man presented with severe gastric ulceration 3 mo after beginning treatment with atorvastatin 20 mg once daily for hypercholesterolemia. The patient was not taking any ulcerogenic drugs and had no evidence of Helicobacter pylori infection. Proton pump inhibitor therapy was initiated and atorvastatin was ...

journal_title：World journal of gastroenterology

authors： El-Hajj II,Mourad FH,Shabb NS,Barada KA

更新日期：2005-05-28 00:00:00

abstract：:AIM:To explore the status of extrahepatic hepatitis C virus (HCV) infection and replication in hepatitis C patients,and its potential implication in HCV infection and pathogenicity.METHODS:By reverse-transcriptase poly-merase chain reaction (RT-PCR),in situ hybridization (ISH) and immunohis-tochemistry, HCV RNA, HCV r...

journal_title：World journal of gastroenterology

authors： Yan FM,Chen AS,Hao F,Zhao XP,Gu CH,Zhao LB,Yang DL,Hao LJ

更新日期：2000-12-01 00:00:00

abstract：:Eosinophilic oesophagitis (EoE) is a chronic, antigen mediated disease of the disease of the oesophagus that may present in both adults and children. It is characterised by intermittent dysphagia, food bolus obstruction and weight loss. The pathogenesis is incompletely understood but is thought to culminate in poor co...

journal_title：World journal of gastroenterology

authors： Attwood SE,Wilson MS

更新日期：2013-02-14 00:00:00

abstract：AIM:To evaluate the prognosis of type II diabetes mellitus (T2DM) after gastrectomy and related factors in gastric cancer patients. METHODS:403 gastric cancer patients with T2DM were studied, who underwent gastrectomy between May 2003 and September 2009. A review of medical records and telephone interviews was perform...

journal_title：World journal of gastroenterology

authors： Kim JW,Cheong JH,Hyung WJ,Choi SH,Noh SH

更新日期：2012-01-07 00:00:00

abstract：AIM:To investigate expression of microRNA (miRNA) and potential targets in chemotherapy resistant esophageal cancer cell lines. METHODS:An in-vitro model of acquired chemotherapy resistance in esophageal adeno- (EAC) and squamous cell carcinoma (ESCC) cells was used, and microRNA expression profiles for cisplatin or 5...

journal_title：World journal of gastroenterology

authors： Hummel R,Sie C,Watson DI,Wang T,Ansar A,Michael MZ,Van der Hoek M,Haier J,Hussey DJ

更新日期：2014-10-28 00:00:00

abstract：AIM:To investigate whether butyrate or glutamine enemas could diminish inflammation in experimental diversion colitis. METHODS:Wistar specific pathogen-free rats were submitted to a Hartmann's end colostomy and treated with enemas containing glutamine, butyrate, or saline. Enemas were administered twice a week in the ...

journal_title：World journal of gastroenterology

authors： Pacheco RG,Esposito CC,Müller LC,Castelo-Branco MT,Quintella LP,Chagas VL,de Souza HS,Schanaider A

更新日期：2012-08-28 00:00:00

abstract：AIM:To evaluate the safety of Curcuma aromatica oil gelatin microspheres (CAO-GMS) infused via hepatic artery against primary liver cancer. METHODS:The safety of CAO-GMS was evaluated in view of its acute toxicity in rats, long-term toxicity in Beagle dogs and general pharmacology in rats and mongrel dogs. RESULTS:Th...

journal_title：World journal of gastroenterology

authors： Deng SG,Wu ZF,Li WY,Yang ZG,Chang G,Meng FZ,Mo LL

更新日期：2004-09-15 00:00:00

abstract：:We report the first case of single port laparoscopic right hemicolectomy for advanced colon cancer. An abdominal 3 cm length incision was made via the umbilicus. A small wound retractor and a surgical glove were used as a single port. All soft tissue anterior to the superior mesenteric vein was completely removed and ...

journal_title：World journal of gastroenterology

authors： Choi SI,Lee KY,Park SJ,Lee SH

更新日期：2010-01-14 00:00:00

abstract：:AIM:To explore the risk factors of gallbladder stone recurrence.METHODS:A multifactorial analysis was made for 1058 patients in Shanghai area whose gallbladder stones disappeared after different kinds of nonsurgical therapy,including oral litholytic therapy, extracorporeal shock wave lithotripsy and percutaneous chole...

journal_title：World journal of gastroenterology

authors： Chen P,Wang BS,He LQ

更新日期：1999-02-01 00:00:00

abstract：AIM:To study the therapeutic effectiveness of intra-tumor injection of Xiao-Zhi-Ling(XZL) on transplanted hepatoma in rats. METHODS:Sixty rats were divided into 3 groups (groups S, X and E), 20 in each. Different drugs were injected into the implanted hepatoma (Group S with 0.2 ml saline as control, group X with 0.2 m...

journal_title：World journal of gastroenterology

authors： Lu Y,Wu LQ

更新日期：2003-09-01 00:00:00

abstract：:Sorafenib, a potent multikinase inhibitor, lead to a significant improvement in progression free survival and overall survival in patients with advanced hepatocellular carcinoma (HCC). Though sorafenib has proven its efficacy in advanced stage HCC, there are limited reports on the role of sorafenib allowing for curati...

journal_title：World journal of gastroenterology

authors： Park JG,Park SY,Lee HW

更新日期：2015-02-28 00:00:00

abstract：AIM:To evaluate the full-spectrum endoscopy (FUSE) colonoscopy system as the first report on the utility thereof in a Korean population. METHODS:We explored the efficacy of the FUSE colonoscopy in a retrospective, single-center feasibility study performed between February 1 and July 20, 2015. A total of 262 subjects (...

journal_title：World journal of gastroenterology

authors： Song JY,Cho YH,Kim MA,Kim JA,Lee CT,Lee MS

更新日期：2016-02-28 00:00:00

abstract：:Dilatation of the colon and the rectum, which is not attributable to aganglionosis, is a rare finding and can be the result of intractable chronic constipation. We report a rare case of a 29-year-old male patient with impressive megacolon, in whom Hirschsprung's or Chagas disease was ruled out. In the present case, di...

journal_title：World journal of gastroenterology

authors： Mecklenburg I,Leibig M,Weber C,Schmidbauer S,Folwaczny C

更新日期：2005-12-28 00:00:00

abstract：AIM:To evaluate the Z-line visualization by the PillCam SB2 using three different ingestion protocols. METHODS:Ninety consecutive patients undergoing small bowel capsule endoscopy (SBCE) between January and May 2008 were included in the study. They swallowed the capsule in the standing (Group A = 30), supine (Group B ...

journal_title：World journal of gastroenterology

authors： Fernandez-Urien I,Borobio E,Elizalde I,Irisarri R,Vila JJ,Urman JM,Jimenez J

更新日期：2010-01-07 00:00:00

abstract：AIM:To study the effect of rosiglitazone, which is a ligand of peroxisome proliferator-activated receptor gamma (PPARgamma), on the expression of PPARgamma in hepatic stellate cells (HSCs) and on the biological characteristics of HSCs. METHODS:The activated HSCs were divided into three groups: control group, 3 micromo...

journal_title：World journal of gastroenterology

authors： Guo YT,Leng XS,Li T,Peng JR,Song SH,Xiong LF,Qin ZZ

更新日期：2005-08-14 00:00:00