Effect of ligand of peroxisome proliferator-activated receptor gamma on the biological characters of hepatic stellate cells.

abstract：AIM:To evaluate the clinical relevance of each cofactor on clinical presentation of chronic hepatitis B. METHODS:Out of 1366 hepatitis B surface antigen (HBsAg) positive subjects consecutively observed in 79 Italian hospitals, 53 (4.3%) showed as the only cofactor hepatitis D virus (HDV) infection [hepatitis B virus (...

journal_title：World journal of gastroenterology

authors： Sagnelli E,Stroffolini T,Mele A,Imparato M,Sagnelli C,Coppola N,Almasio PL

更新日期：2012-04-14 00:00:00

abstract：:AIM:To clone core gene cDNA of Chinese hepatitis C virus (HCV) into eukaryotic expression vector cosmid pTM3 and to express HCV core antigen in HepG2 cells.METHODS:Core gene cDNA of HCV was introduced into eukaryotic expression vector cosmid pTM3.Using vaccinia virus/bacteriophage T7 hybrid expression system, HepG2 ce...

journal_title：World journal of gastroenterology

authors： Jiang RL,Lu QS,Luo KX

更新日期：2000-04-01 00:00:00

abstract：AIM:To investigate the antibacterial effects of a crude extract of maggots against Escherichia coli (E. coli) and the underlying mechanisms, and to separate and purify the crude extract of maggots to assess the antibacterial effects of the active ingredients in the crude extract. METHODS:Different concentrations of th...

journal_title：World journal of gastroenterology

authors： Ge QS,Zhang HM,Liu X,Wang SY,Lv DC,Li XD

更新日期：2015-02-07 00:00:00

abstract：BACKGROUND:The role of the Notch pathway in carcinogenesis and tumor progression has been demonstrated in many organs, including the colon. Accordingly, studies aimed at developing therapies targeting this pathway in various cancers require the identification of several factors that may play a role in regulating Notch-...

journal_title：World journal of gastroenterology

authors： Gonulcu SC,Unal B,Bassorgun IC,Ozcan M,Coskun HS,Elpek GO

更新日期：2020-07-14 00:00:00

abstract：AIM:To seek the X associated protein (XAP) with the constructed bait vector pAS2-1X from normal human liver cDNA library. METHODS:The X region of the HBV gene was amplied by PCR and cloned into the eukaryotic expression vector pAS2-1. The reconstituted plasmid pAS2-1X was transformed into the yeast cells and the expre...

journal_title：World journal of gastroenterology

authors： Wang XZ,Jiang XR,Chen XC,Chen ZX,Li D,Lin JY,Tao QM

更新日期：2002-02-01 00:00:00

abstract：AIM:To investigate the effects of extended lymphadenectomy and postoperative chemotherapy on gastric cancer without lymph node metastasis. METHODS:Clinical data of 311 node-negative gastric cancer patients who underwent potentially curative gastrectomy with more than 15 lymph nodes resected, from January 2002 to Decem...

journal_title：World journal of gastroenterology

authors： Xue Q,Wang XN,Deng JY,Zhang RP,Liang H

更新日期：2013-09-07 00:00:00

abstract：AIM:To investigate the frequency of occult hepatitis B, the clinical course of hepatitis B virus (HBV) reactivation and reverse seroconversion and associated risk factors in autologous hematopoietic stem cell transplantation (HSCT) recipients. METHODS:This study was conducted in 90 patients undergoing autologous HSCT....

journal_title：World journal of gastroenterology

authors： Ceneli O,Ozkurt ZN,Acar K,Rota S,Aki SZ,Yeğin ZA,Yağci M,Ozenirler S,Sucak GT

更新日期：2010-04-14 00:00:00

abstract：AIM:To evaluate the clinical outcomes and safety of anterior- and conventional-approach hepatectomy for patients with large liver tumors. METHODS:PubMed, EMBASE, Google Scholar and the Cochrane Library databases were searched for randomized controlled trials (RCTs) and controlled clinical trials comparing anterior-app...

journal_title：World journal of gastroenterology

authors： Li L,Wang HQ,Wang Q,Yang J,Yang JY

更新日期：2014-12-07 00:00:00

abstract：:Endoscopic ultrasound (EUS)-guided biliary drainage is accepted as a less invasive, alternative treatment for patients in whom endoscopic retrograde cholangiopancreatography has failed. Most patients with malignant hilar obstruction undergo EUS-guided hepaticogastrostomy. The authors present the case of a 77-year-old ...

journal_title：World journal of gastroenterology

authors： Prachayakul V,Aswakul P

更新日期：2015-09-14 00:00:00

abstract：AIM:To prepare the chitosan-pmEpo nanoparticles and to study their ability for transcellular and paracellular transport across intestinal epithelia by oral administration. METHODS:ICR mice were fed with recombinant plasmid AAV-tetO-CMV-mEpo (containing mEpo gene) or pCMVbeta(containing LacZ gene), whether it was wrapp...

journal_title：World journal of gastroenterology

authors： Chen J,Yang WL,Li G,Qian J,Xue JL,Fu SK,Lu DR

更新日期：2004-01-01 00:00:00

abstract：AIM:To assess the clinical outcomes of pre-, pro- and synbiotics therapy in patients with acute pancreatitis. METHODS:The databases including Medline, Embase, the Cochrane Library, Web of Science and Chinese Biomedicine Database were searched for all relevant randomized controlled trials that studied the effects of pr...

journal_title：World journal of gastroenterology

authors： Zhang MM,Cheng JQ,Lu YR,Yi ZH,Yang P,Wu XT

更新日期：2010-08-21 00:00:00

abstract：:The Prague C and M Criteria have been developed for the objective endoscopic diagnosis of Barrett's esophagus (BE). BE arises between the squamocolumnar junction and the gastroesophageal junction at the proximal margin of the gastric folds. In this study, we reported that 43.0% of the subjects examined were diagnosed ...

journal_title：World journal of gastroenterology

authors： Akiyama T,Sekino Y,Iida H,Koyama S,Gotoh E,Maeda S,Nakajima A,Inamori M

更新日期：2012-07-14 00:00:00

abstract：AIM:To highlight magnetic resonance enterography (MRE) for diagnosis of patients with refractory iron deficiency anemia and normal endoscopy results. METHODS:Fifty-three patients diagnosed with iron deficiency anemia refractory to treatment and normal gastroscopy and colonoscopy results were admitted to this prospecti...

journal_title：World journal of gastroenterology

authors： Cengic I,Tureli D,Aydin H,Bugdayci O,Imeryuz N,Tuney D

更新日期：2014-10-14 00:00:00

abstract：:Intratumoral heterogeneity including genetic and nongenetic mechanisms refers to biological differences amongst malignant cells originated within the same tumor. Both, cell differentiation hierarchy and stochasticity in gene expression and signaling pathways may result in phenotypic differences of cancer cells. Since ...

journal_title：World journal of gastroenterology

authors： Sipos F,Constantinovits M,Műzes G

更新日期：2014-03-14 00:00:00

abstract：AIM:To assess the outcome of patients, who underwent transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) and subsequently liver transplantation (OLT) irrespective of tumor size when no tumor progression was observed. METHODS:Records, imaging studies and pathology of 84 patients with HCC were revi...

journal_title：World journal of gastroenterology

authors： Obed A,Beham A,Püllmann K,Becker H,Schlitt HJ,Lorf T

更新日期：2007-02-07 00:00:00

abstract：AIM:To evaluate the predictive value of preoperative predictors for portal vein thrombosis (PVT) after splenectomy with periesophagogastric devascularization. METHODS:In this prospective study, 69 continuous patients with portal hypertension caused by hepatitis B cirrhosis underwent splenectomy with periesophagogastri...

journal_title：World journal of gastroenterology

authors： Zhang Y,Wen TF,Yan LN,Yang HJ,Deng XF,Li C,Wang C,Liang GL

更新日期：2012-04-21 00:00:00

abstract：:Crohn's disease (CD) is a chronic inflammatory condition that plagues millions all over the world. This debilitating bowel disease can start in early childhood and continue into late adulthood. Signs and symptoms are usually many and multiple tests are often required for the diagnosis and confirmation of this disease....

journal_title：World journal of gastroenterology

authors： Naser SA,Sagramsingh SR,Naser AS,Thanigachalam S

更新日期：2014-06-21 00:00:00

abstract：AIM:To assess the patient-reported outcomes (PROs) of pancreatic neuroendocrine tumor (PNET) patients. METHODS:Fifty-one consecutive patients (21 male, 30 female, 61.0 +/- 10.3 years) with proven PNETs were studied. An SF-12 questionnaire capable of exploring the physical (PCS) and mental (MCS) aspects of daily life w...

journal_title：World journal of gastroenterology

authors： Pezzilli R,Campana D,Morselli-Labate AM,Fabbri MC,Brocchi E,Tomassetti P

更新日期：2009-10-28 00:00:00

abstract：AIM:To study the influence of redox environment of Escherichia coli (E. coli) cytoplasm on disulfide bond formation of recombinant proteins. METHODS:Bovine fibroblast growth factor (BbFGF) was selected as a model of simple proteins with a single disulfide bond and free cysteines. Anti-HBsAg single-chain Fv (HBscFv), a...

journal_title：World journal of gastroenterology

authors： Xiong S,Wang YF,Ren XR,Li B,Zhang MY,Luo Y,Zhang L,Xie QL,Su KY

更新日期：2005-02-21 00:00:00

abstract：AIM:To investigate the effects of combined use of emodin and baicalein (CEB) at the cellular and organism levels in severe acute pancreatitis (SAP) and explore the underlying mechanism. METHODS:SAP was induced by retrograde infusion of 5% sodium taurocholate into the pancreatic duct in 48 male SD rats. Pancreatic hist...

journal_title：World journal of gastroenterology

authors： Li J,Zhou R,Bie BB,Huang N,Guo Y,Chen HY,Shi MJ,Yang J,Zhang J,Li ZF

更新日期：2018-01-07 00:00:00

abstract：AIM:To investigate the effects of early enteral nutrition (EEN) on the immune function and clinical outcome of patients with severe acute pancreatitis (SAP). METHODS:Patients were randomly allocated to receive EEN or delayed enteral nutrition (DEN). Enteral nutrition was started within 48 h after admission in EEN grou...

journal_title：World journal of gastroenterology

authors： Sun JK,Mu XW,Li WQ,Tong ZH,Li J,Zheng SY

更新日期：2013-02-14 00:00:00

abstract：:Intrahepatic clear cell cholangiocarcinoma is very rare - only 8 cases have been reported. A 56-year-old Japanese man with chronic hepatitis B infection was diagnosed with a 2.2 cm hepatocellular carcinoma on imaging, and hepatic segmentectomy was performed. Histopathologically, the tumor cells had copious clear cytop...

journal_title：World journal of gastroenterology

authors： Toriyama E,Nanashima A,Hayashi H,Abe K,Kinoshita N,Yuge S,Nagayasu T,Uetani M,Hayashi T

更新日期：2010-05-28 00:00:00

abstract：AIM:To evaluate the effects of DA-9701 on the gastric emptying of a solid meal using the ¹³C-octanoic acid breath test in a mouse model. METHODS:Male C57BL/6 mice aged > 8 wk and with body weights of 20-25 g were used in this study. The solid test meal consisted of 200 mg of egg yolk labeled with 1.5 L/g ¹³C-octanoic ...

journal_title：World journal of gastroenterology

authors： Lim CH,Choi MG,Park H,Baeg MK,Park JM

更新日期：2013-07-21 00:00:00

abstract：AIM:To investigate the role of reactive oxygen species (ROS) in ethanol-mediated cell death of polarized hepatic (WIF-B) cells. METHODS:In this work, WIF-B cultures were treated with pyrazole (inducer of cytochrome P4502E1, CYP2E1) and/or L-buthionine sulfoximine (BSO), a known inhibitor of hepatic glutathione (GSH), ...

journal_title：World journal of gastroenterology

authors： McVicker BL,Tuma PL,Kharbanda KK,Lee SM,Tuma DJ

更新日期：2009-06-07 00:00:00

abstract：:Duodenal polyps or lesions are uncommonly found on upper endoscopy. Duodenal lesions can be categorized as subepithelial or mucosally-based, and the type of lesion often dictates the work-up and possible therapeutic options. Subepithelial lesions that can arise in the duodenum include lipomas, gastrointestinal stromal...

journal_title：World journal of gastroenterology

authors： Gaspar JP,Stelow EB,Wang AY

更新日期：2016-01-14 00:00:00

abstract：AIM:To investigate whether Dihydromyricetin (DHM) inhibits cell proliferation and promotes apoptosis by downregulating Notch1 expression. METHODS:The correlation between Notch1 and Hes1 (a Notch1 target molecule) expression in hepatoma samples was confirmed by qRT-PCR. In addition, MTT assays, flow cytometry and TUNEL...

journal_title：World journal of gastroenterology

authors： Lu CJ,He YF,Yuan WZ,Xiang LJ,Zhang J,Liang YR,Duan J,He YH,Li MY

更新日期：2017-09-14 00:00:00

abstract：AIM:To analyze the clinicopathologic features and the prognosis of primary intestinal lymphoma. METHODS:Patients were included in the study based on standard diagnostic criteria for primary gastrointestinal lymphoma, and were treated at Sun Yat-sen University Cancer Centre between 1993 and 2008. RESULTS:The study com...

journal_title：World journal of gastroenterology

authors： Wang GB,Xu GL,Luo GY,Shan HB,Li Y,Gao XY,Li JJ,Zhang R

更新日期：2011-11-07 00:00:00

abstract：:There have been multiple NOD2/CARD15 genotype-phenotype analyses undertaken in patients with Crohn's disease since the gene's discovery in 2001. This review focuses on the major published series based upon their size and on the presence of specific clinical and genetic information provided in the published material fr...

journal_title：World journal of gastroenterology

authors： Radford-Smith G,Pandeya N

更新日期：2006-11-28 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) in children is becoming a major health concern. A "multiple-hit" pathogenetic model has been suggested to explain the progressive liver damage that occurs among children with NAFLD. In addition to the accumulation of fat in the liver, insulin resistance (IR) and oxidative stre...

journal_title：World journal of gastroenterology

authors： Clemente MG,Mandato C,Poeta M,Vajro P

更新日期：2016-09-28 00:00:00

abstract：AIM:To compare long-term occurrence of gastroesophageal reflux disease (GERD) between two different types of peroral endoscopic myotomy (POEM) for achalasia. METHODS:We included all patients with achalasia who underwent POEM at our hospital from August 2011 to October 2012 and had complete GERD evaluation with ≥ 3 yea...

journal_title：World journal of gastroenterology

authors： Wang XH,Tan YY,Zhu HY,Li CJ,Liu DL

更新日期：2016-11-14 00:00:00