Transfection of mEpo gene to intestinal epithelium in vivo mediated by oral delivery of chitosan-DNA nanoparticles.

abstract：:Portal hypertension, liver fibrosis, and angiosarcoma of the liver (ASL) have been reported among workers exposed to vinyl chloride monomer (VCM) since the 1970s. In 2007, the International Agency for Research on Cancer established the association of VCM with hepatocellular carcinoma (HCC), though only on the basis of...

journal_title：World journal of gastroenterology

authors： Fedeli U,Girardi P,Mastrangelo G

更新日期：2019-09-07 00:00:00

abstract：AIM:To present our experience with tuberculous peritonitis treated in our hospital from 2002-2007. METHODS:We reviewed the medical records of 9 children with tuberculous peritonitis. RESULTS:Nine patients (5 boys, 4 girls) of mean age 14.2 years were diagnosed with peritoneal tuberculosis. All patients presented with...

journal_title：World journal of gastroenterology

authors： Dinler G,Sensoy G,Helek D,Kalayci AG

更新日期：2008-12-21 00:00:00

abstract：:Endoscopic retrograde cholangiopancreatography (ERCP) is a state of the art diagnostic and therapeutic procedure for various pancreatic and biliary problems. In spite of the well-established safety of the procedure, there is still a risk of complications such as pancreatitis, cholangitis, bleeding and perforation. Air...

journal_title：World journal of gastroenterology

authors： Yilmaz B,Roach EC,Koklu S,Aydin O,Unlu O,Kilic YA

更新日期：2015-04-21 00:00:00

abstract：AIM:To analyze the current available evidence of Kudo's pit pattern classification for diagnosing colorectal neoplasms. METHODS:A search was performed on Pubmed/Embase to identify studies reporting the outcomes of the pit pattern classification in colorectal polyps. Retrieved records were evaluated and selected by two...

journal_title：World journal of gastroenterology

authors： Li M,Ali SM,Umm-a-OmarahGilani S,Liu J,Li YQ,Zuo XL

更新日期：2014-09-21 00:00:00

abstract：AIM:To determine whether bispectral index (BIS) monitoring is useful for propofol administration for deep sedation during endoscopic retrograde cholangiopancreatography (ERCP). METHODS:Fifty-nine consecutive patients with a variety of reasons for ERCP who underwent the procedure at least twice between 1 July 2010 and ...

journal_title：World journal of gastroenterology

authors： Jang SY,Park HG,Jung MK,Cho CM,Park SY,Jeon SW,Tak WY,Kweon YO,Kim SK,Jeon YH

更新日期：2012-11-21 00:00:00

abstract：AIM:To investigate the antioxidant effect of caffeic acid phenethyl ester (CAPE) in hepatic stellate cell-T6 (HSC-T6) cells cultured in vitro and the potential mechanisms. METHODS:HSC-T6 cells were cultured in vitro and treated with various concentrations of CAPE for 24, 48 and 72 h, respectively. Cell proliferation w...

journal_title：World journal of gastroenterology

authors： Yang N,Shi JJ,Wu FP,Li M,Zhang X,Li YP,Zhai S,Jia XL,Dang SS

更新日期：2017-02-21 00:00:00

abstract：AIM:To investigate the role of insulin-like growth factor binding protein-7 (IGFBP-7) in the activation and transdifferentiation of hepatic stellate cells (HSC) in vitro. METHODS:Rat HSC-T6 cells were cultured in separate dishes and treated with various concentration of transforming growth factor (TGF)-beta(1), IGFBP-...

journal_title：World journal of gastroenterology

authors： Liu LX,Huang S,Zhang QQ,Liu Y,Zhang DM,Guo XH,Han DW

更新日期：2009-07-14 00:00:00

abstract：AIM:To evaluate retrospectively the correlation between enhancement patterns on dynamic computed tomography (CT) and angiogenesis and fibrosis in pancreatic adenocarcinoma. METHODS:Twenty-three patients with pancreatic adenocarcinoma underwent dynamic CT and tumor resection. In addition to the absolute and relative en...

journal_title：World journal of gastroenterology

authors： Hattori Y,Gabata T,Matsui O,Mochizuki K,Kitagawa H,Kayahara M,Ohta T,Nakanuma Y

更新日期：2009-07-07 00:00:00

abstract：AIM:To investigate whether Dihydromyricetin (DHM) inhibits cell proliferation and promotes apoptosis by downregulating Notch1 expression. METHODS:The correlation between Notch1 and Hes1 (a Notch1 target molecule) expression in hepatoma samples was confirmed by qRT-PCR. In addition, MTT assays, flow cytometry and TUNEL...

journal_title：World journal of gastroenterology

authors： Lu CJ,He YF,Yuan WZ,Xiang LJ,Zhang J,Liang YR,Duan J,He YH,Li MY

更新日期：2017-09-14 00:00:00

abstract：:Colorectal cancer (CRC) is a common health problem, representing the third most commonly diagnosed cancer worldwide and causing a significant burden in terms of morbidity and mortality, with annual deaths estimated at 700000. The western way of life, that is being rapidly adopted in many regions of the world, is a wel...

journal_title：World journal of gastroenterology

authors： Hadjipetrou A,Anyfantakis D,Galanakis CG,Kastanakis M,Kastanakis S

更新日期：2017-09-07 00:00:00

abstract：:An appendiceal neurofibroma (ANF) is a rare neoplasm associated with neurofibromatosis type 1(NF-1), an inheritable neurocutaneous disorder that involves multiple systems including the intraabdominal organs. Appendiceal diverticulitis occasionally ruptures in the absence of intense abdominal pain, which can lead to se...

journal_title：World journal of gastroenterology

authors： Ozaki A,Tsukada M,Watanabe K,Tsubokura M,Kato S,Tanimoto T,Kami M,Ohira H,Kanazawa Y

更新日期：2015-09-07 00:00:00

abstract：:The severity of fecal incontinence widely varies and can have dramatic devastating impacts on a person's life. Fecal incontinence is common, though it is often under-reported by patients. In addition to standard treatment options, new treatments have been developed during the past decade to attempt to effectively trea...

journal_title：World journal of gastroenterology

authors： Van Koughnett JA,Wexner SD

更新日期：2013-12-28 00:00:00

abstract：:Inflammatory bowel disease is an important cause of gastrointestinal pathology in children and adolescents. The incidence of pediatric inflammatory bowel disease is increasing; therefore, it is important for the clinician to be aware of the presentation of this disease in the pediatric population. Laboratory tests, ra...

journal_title：World journal of gastroenterology

authors： Diefenbach KA,Breuer CK

更新日期：2006-05-28 00:00:00

abstract：AIM:To characterize AXL receptor tyrosine kinase (AXL) expression in relationship to tumor protein P53 (TP53 gene, p53 protein) and its role in tumor invasion and response to therapy. METHODS:We used 14 cell lines, including 3 isogenic pairs carrying mutant/knockout p53, to gain insight into the relationship between A...

journal_title：World journal of gastroenterology

authors： Abdel-Rahman WM,Al-Khayyal NA,Nair VA,Aravind SR,Saber-Ayad M

更新日期：2017-05-21 00:00:00

abstract：AIM:To examine the association between obesity-related adipokines (adiponectin, leptin, resistin, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) and colorectal cancer (CRC) risk. METHODS:Serum levels of adipokines were measured in 100 CRC patients and age- and sex-matched controls for the data analysis. Unc...

journal_title：World journal of gastroenterology

authors： Joshi RK,Kim WJ,Lee SA

更新日期：2014-06-28 00:00:00

abstract：:The anti-tumor necrosis factor (TNF)alpha medications demonstrate efficacy in the induction of remission and its maintenance in numerous chronic inflammatory conditions. With the increasing number of patients receiving anti-TNFalpha agents, however, less common adverse reactions will occur. Cutaneous eruptions complic...

journal_title：World journal of gastroenterology

authors： Salama M,Lawrance IC

更新日期：2009-09-21 00:00:00

abstract：:Metastases of esophageal carcinoma to the skeletal muscle are rare, but the incidence may be increasing because of better diagnosis resulting from widespread use of positron emission tomography/computed tomography (PET/CT). A cohort of 205 patients with esophageal carcinoma treated at our center who had PET/CT between...

journal_title：World journal of gastroenterology

authors： Cincibuch J,Mysliveček M,Melichar B,Neoral C,Metelková I,Zezulová M,Procházková-Študentová H,Flodr P,Zlevorová M,Aujeský R,Cwiertka K

更新日期：2012-09-21 00:00:00

abstract：:Epidemiological and clinical data point to a close association between chronic hepatitis B virus infection or chronic hepatitis C virus infection and development of hepatocellular carcinoma (HCC). HCC develops over several decades and is associated with fibrosis. This sequence suggests that persistent viral infection ...

journal_title：World journal of gastroenterology

authors： Murata M,Yoshida K,Yamaguchi T,Matsuzaki K

更新日期：2014-11-07 00:00:00

abstract：AIM:To evaluate ATP-binding cassette (ABC) transporters in colonic pathophysiology as they had recently been related to colorectal cancer (CRC) development. METHODS:Literature search was conducted on PubMed using combinations of the following terms: ABC transporters, ATP binding cassette transporter proteins, inflamma...

journal_title：World journal of gastroenterology

authors： Andersen V,Svenningsen K,Knudsen LA,Hansen AK,Holmskov U,Stensballe A,Vogel U

更新日期：2015-11-07 00:00:00

abstract：:Ulcerative colitis (UC) is a chronic inflammatory bowel condition characterised by a relapsing and remitting course. Symptom control has been the traditional mainstay of medical treatment. It is well known that histological inflammatory activity persists despite adequate symptom control and absence of endoscopic infla...

journal_title：World journal of gastroenterology

authors： Mohammed N,Subramanian V

更新日期：2016-11-14 00:00:00

abstract：BACKGROUND:Laparoscopy has been widely used in general surgical procedures, but total laparoscopic pancreaticoduodenectomy (TLPD) is still a complex and challenging surgery that is only performed in a small number of patients at a few large academic medical centers. Although the safety and feasibility of TLPD have been...

journal_title：World journal of gastroenterology

authors： Zhang H,Lan X,Peng B,Li B

更新日期：2019-10-07 00:00:00

abstract：AIM:To clarify the value of combined use of markers for the diagnosis of gallbladder cancer and prediction of its prognosis. METHODS:Serum cancer antigens (CA)199, CA242, carcinoembryonic antigen (CEA), and CA125 levels were measured in 78 patients with gallbladder cancer (GBC), 78 patients with benign gallbladder dis...

journal_title：World journal of gastroenterology

authors： Wang YF,Feng FL,Zhao XH,Ye ZX,Zeng HP,Li Z,Jiang XQ,Peng ZH

更新日期：2014-04-14 00:00:00

abstract：:During the last decades, further knowledge of hepatocellular carcinoma (HCC) molecular mechanisms has led to development of effective systemic treatments including tyrosine kinase inhibitors (TKIs) and immunotherapy. In this review, we describe first and second line systemic treatment options for advanced HCC. Several...

journal_title：World journal of gastroenterology

authors： Piñero F,Silva M,Iavarone M

更新日期：2020-04-28 00:00:00

abstract：AIM:To investigate genetic factors that might help define which Crohn's disease (CD) patients are likely to benefit from anti-tumor necrosis factor (TNF) therapy. METHODS:This was a prospective cohort study. Patients were recruited from a university digestive disease practice database. We included CD patients who rece...

journal_title：World journal of gastroenterology

authors： Netz U,Carter JV,Eichenberger MR,Dryden GW,Pan J,Rai SN,Galandiuk S

更新日期：2017-07-21 00:00:00

abstract：:Inflammatory bowel diseases (IBD) can be really considered to be systemic diseases since they are often associated with extraintestinal manifestations, complications, and other autoimmune disorders. Indeed, physicians who care for patients with ulcerative colitis and Crohn's disease, the two major forms of IBD, face a...

journal_title：World journal of gastroenterology

authors： Danese S,Semeraro S,Papa A,Roberto I,Scaldaferri F,Fedeli G,Gasbarrini G,Gasbarrini A

更新日期：2005-12-14 00:00:00

abstract：:Acute hepatic failure due to hepatitis B virus (HBV) can occur both during primary infection as well as after reactivation of chronic infection. Guidelines recommend considering antiviral therapy in both situations, although evidence supporting this recommendation is weak. Since HBV is not directly cytopathic, the mec...

journal_title：World journal of gastroenterology

authors： Bockmann JH,Dandri M,Lüth S,Pannicke N,Lohse AW

更新日期：2015-02-21 00:00:00

abstract：:Heterotopic pancreatic tissue within the stomach is rare and dysplasia within heterotopic pancreatic tissue is very rare. We present the first report of a patient with concurrent occurrence of heterotopic pancreas in the stomach with a gastrointestinal stromal tumour. ...

journal_title：World journal of gastroenterology

authors： Kaufman A,Storey D,Lee CS,Murali R

更新日期：2007-11-21 00:00:00

abstract：:Many epidemiological reports indicate that Helicobacter pylori (H pylori) infection plays an important role in gastric carcinogenesis. Several genetic and epigenetic alterations contribute to the initiation, promotion, and progression of the cancer cells in a multi-step manner. H pylori is known to induce chronic infl...

journal_title：World journal of gastroenterology

authors： Ito M,Tanaka S,Kamada T,Haruma K,Chayama K

更新日期：2006-01-07 00:00:00

abstract：AIM:To evaluate a laparoscopic approach to gallbladder lesions including polyps, wall-thickening lesions, and suspected T1 and T2 gallbladder cancer (GBC). METHODS:We performed 50 cases of laparoscopic whole-layer cholecystectomy (LCWL) and 13 cases of laparoscopic gallbladder bed resection (LCGB) for those gallbladde...

journal_title：World journal of gastroenterology

authors： Ome Y,Hashida K,Yokota M,Nagahisa Y,Okabe M,Kawamoto K

更新日期：2017-04-14 00:00:00

abstract：AIM:To investigate control of two different types of massive presacral bleeding according to the anatomy of the presacral venous system. METHODS:A retrospective review was performed in 1628 patients with middle or low rectal carcinoma who were treated surgically in the Department of Colorectal Surgery, Changhai Hospit...

journal_title：World journal of gastroenterology

authors： Lou Z,Zhang W,Meng RG,Fu CG

更新日期：2013-07-07 00:00:00