Sequencing of systemic treatment for hepatocellular carcinoma: Second line competitors.

abstract：AIM:To identify the diagnostic value of colonoscopy for diverticulosis as determined by barium enema. METHODS:A total of 65 patients with hematochezia who underwent colonoscopy and barium enema were analyzed, and the diagnostic value of colonoscopy for diverticula was assessed. The receiver operating characteristic ar...

journal_title：World journal of gastroenterology

authors： Niikura R,Nagata N,Shimbo T,Akiyama J,Uemura N

更新日期：2013-04-21 00:00:00

abstract：AIM:To study the influence of redox environment of Escherichia coli (E. coli) cytoplasm on disulfide bond formation of recombinant proteins. METHODS:Bovine fibroblast growth factor (BbFGF) was selected as a model of simple proteins with a single disulfide bond and free cysteines. Anti-HBsAg single-chain Fv (HBscFv), a...

journal_title：World journal of gastroenterology

authors： Xiong S,Wang YF,Ren XR,Li B,Zhang MY,Luo Y,Zhang L,Xie QL,Su KY

更新日期：2005-02-21 00:00:00

abstract：AIM:To investigate the association of seven single nucleotide polymorphisms (SNPs) of the IL23R gene with the clinical picture of ulcerative colitis (UC). METHODS:Genomic DNA samples of 131 patients (66 males, 65 females, mean age 55.4 ± 15.8 years) with Caucasian origin, diagnosed with UC were investigated. The diagn...

journal_title：World journal of gastroenterology

authors： Fischer S,Kövesdi E,Magyari L,Csöngei V,Hadzsiev K,Melegh B,Hegyi P,Sarlós P

更新日期：2017-01-21 00:00:00

abstract：AIM:To investigate the association between babA2 gene and peptic ulcer disease (PUD) and gastric cancer (GC) in Helicobacter pylori-infected populations. METHODS:We evaluated the relationship between babA2 and clinical outcomes (PUD and GC) using a meta-analysis. A literature search was performed using the PubMed and ...

journal_title：World journal of gastroenterology

authors： Chen MY,He CY,Meng X,Yuan Y

更新日期：2013-07-14 00:00:00

abstract：:Diarrhea after bariatric procedures, mainly those with malabsorptive elements including Roux-Y Gastric Bypass and Biliopancreatic Diversion, is common and an essential determinant of quality of life and micro- and macronutrient deficiencies. Bariatric surgery is the only sustainably successful method to address morbid...

journal_title：World journal of gastroenterology

authors： Borbély YM,Osterwalder A,Kröll D,Nett PC,Inglin RA

更新日期：2017-07-14 00:00:00

abstract：:Although gastroduodenal ulcers are common in solid organ transplant patients, there are few reports on multiple giant ulcers in the distal ileum and ileocecal valve caused by immunosuppressants Herein, we report on a liver transplant recipient and a renal transplant recipient with multiple large ulcers in the distal i...

journal_title：World journal of gastroenterology

authors： Guo YW,Gu HY,Abassa KK,Lin XY,Wei XQ

更新日期：2016-06-28 00:00:00

abstract：AIM:To seek the X associated protein (XAP) with the constructed bait vector pAS2-1X from normal human liver cDNA library. METHODS:The X region of the HBV gene was amplied by PCR and cloned into the eukaryotic expression vector pAS2-1. The reconstituted plasmid pAS2-1X was transformed into the yeast cells and the expre...

journal_title：World journal of gastroenterology

authors： Wang XZ,Jiang XR,Chen XC,Chen ZX,Li D,Lin JY,Tao QM

更新日期：2002-02-01 00:00:00

abstract：AIM:To compare the causes and clinical outcome of patients with acute upper gastrointestinal bleeding (AUGB) and a history of gastric surgery to those with AUGB but without a history of gastric surgery in the past. METHODS:The causes and clinical outcome were compared between 105 patients with AUGB and a history of ga...

journal_title：World journal of gastroenterology

authors： Nikolopoulou VN,Thomopoulos KC,Theocharis GI,Arvaniti VA,Vagianos CE

更新日期：2005-08-07 00:00:00

abstract：AIM:To determine whether increased blood flow of the liver can cause oxidative stress and hepatocyte damage, and to elaborate methods suitable for measuring the antioxidant defence during hepatic surgery on rat model. METHODS:In nembutal narcosis, the left lateral and the medial lobes of the liver were clipped for 45 ...

journal_title：World journal of gastroenterology

authors： Váli L,Taba G,Szentmihályi K,Fébel H,Kurucz T,Pallai Z,Kupcsulik P,Blázovics A

更新日期：2006-02-21 00:00:00

abstract：AIM:To study the response to infliximab in pediatric inflammatory bowel disease (IBD), as reflected in fecal calprotectin levels. METHODS:Thirty-six pediatric patients with IBD [23 Crohn's disease (CD), 13 ulcerative colitis (UC); median age 14 years] were treated with infliximab. Fecal calprotectin was measured at ba...

journal_title：World journal of gastroenterology

authors： Hämäläinen A,Sipponen T,Kolho KL

更新日期：2011-12-21 00:00:00

abstract：AIM:To study the effect of IGF-1/IGF-1R and gastrin/CCK-BR on carcinogenesis and development of human gastric carcinoma and to explore its mechanism and provide a credible theoretical foundation for early diagnosis and molecular therapy of gastric carcinoma. METHODS:mRNA expression levels of IGF-1/IGF-1R and gastrin/C...

journal_title：World journal of gastroenterology

authors： Zhao MD,Hu XM,Sun DJ,Zhang Q,Zhang YH,Meng W

更新日期：2005-06-07 00:00:00

abstract：:Weight loss supplements often contain powerful pharmacoactive ingredients with the potential to cause harm. Trials used to determine product safety and effectiveness, meanwhile, tend to be small, of short duration, and frequently lack financial conflict of interest disclosures. These factors could conspire to place co...

journal_title：World journal of gastroenterology

authors： Lobb A

更新日期：2010-10-14 00:00:00

abstract：:Irritable bowel syndrome (IBS) is an extremely prevalent but poorly understood gastrointestinal disorder. Consequently, there are no clear diagnostic markers to help diagnose the disorder and treatment options are limited to management of the symptoms. The concept of a dysregulated gut-brain axis has been adopted as a...

journal_title：World journal of gastroenterology

authors： Kennedy PJ,Cryan JF,Dinan TG,Clarke G

更新日期：2014-10-21 00:00:00

abstract：:Cancer patients have unique problems associated with hepatitis C virus (HCV) infection and treatment not seen in the general population. HCV infection poses additional challenges and considerations for the management of cancer, and vice versa. HCV infection also can lead to the development of cancer, particularly hepa...

journal_title：World journal of gastroenterology

authors： Borchardt RA,Torres HA

更新日期：2014-03-21 00:00:00

abstract：AIM:To investigate the effect of bile acid on the expression of histidine decarboxylase (HDC), which is a major enzyme involved in histamine production, and gene expression of gastric transcription factors upon cooperative activation. METHODS:HDC expression was examined by immunohistochemistry, reverse transcriptase p...

journal_title：World journal of gastroenterology

authors： Ku HJ,Kim HY,Kim HH,Park HJ,Cheong JH

更新日期：2014-01-07 00:00:00

abstract：AIM:To select the peptide mimicking the neutralization epitope of hepatitis E virus which bound to non-type-specific and conformational monoclonal antibodies (mAbs) 8C11 and 8H3 fromed 7-peptide phage display library, and expressed the peptide recombinant with HBcAg in E.coli, and to observe whether the recombinant HBc...

journal_title：World journal of gastroenterology

authors： Gu Y,Zhang J,Wang YB,Li SW,Yang HJ,Luo WX,Xia NS

更新日期：2004-06-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) ranges from simple steatosis to nonalcoholic steatohepatitis (NASH), leading to fibrosis and potentially cirrhosis, and it is one of the most common causes of liver disease worldwide. NAFLD is associated with other medical conditions such as metabolic syndrome, obesity, cardio...

journal_title：World journal of gastroenterology

authors： Schwenger KJ,Allard JP

更新日期：2014-02-21 00:00:00

abstract：AIM:To examine the possible effects of honey supplementation on hepatic damage due to obstruction of the common bile duct in an experimental rat model. METHODS:The study was performed with 30 male rats divided into three groups: a sham group, an obstructive jaundice group, and an obstructive jaundice plus honey group....

journal_title：World journal of gastroenterology

authors： Erguder BI,Kilicoglu SS,Namuslu M,Kilicoglu B,Devrim E,Kismet K,Durak I

更新日期：2008-06-21 00:00:00

abstract：AIM:To investigate the association between TP53 Arg72Pro polymorphism and esophageal cancer (EC) risk using meta-analysis. METHODS:All eligible studies published before March 1, 2010 were selected by searching PubMed using keywords "p53" or "TP53", "polymorphism" or "variation", "esophageal" and "cancer" or "carcinoma...

journal_title：World journal of gastroenterology

authors： Jiang DK,Yao L,Wang WZ,Peng B,Ren WH,Yang XM,Yu L

更新日期：2011-03-07 00:00:00

abstract：AIM:To develop a conditionally replicative gene-viral vector system called CNHK500-p53, which contains dual promoters within the E1 region, and combines the advantages of oncolytic virus and gene therapies for hepatocellular carcinoma (HCC). METHODS:CNHK500-p53 was constructed by using human telomerase reverse transcr...

journal_title：World journal of gastroenterology

authors： Zhao HC,Zhang Q,Yang Y,Lu MQ,Li H,Xu C,Chen GH

更新日期：2007-02-07 00:00:00

abstract：AIM:To hypothesize that beta-7 integrin affects cellular migration of both, lymphocytes and enterocytes. METHODS:The nucleoside analog BrdU was ip injected in beta-7-deficient mice (C57BL/6-Itgb(tmlcgn)/J) of male gender and age-matched male C57BL/J J mice (wild type) 4, 20, or 40 h before analysis. The total small in...

journal_title：World journal of gastroenterology

authors： Kaemmerer E,Kuhn P,Schneider U,Clahsen T,Jeon MK,Klaus C,Andruszkow J,Härer M,Ernst S,Schippers A,Wagner N,Gassler N

更新日期：2015-02-14 00:00:00

abstract：:This review focused in the perioperative management of patients with pancreatic cancer in order to improve the outcome of the disease. We consider that the most controversial points in pancreatic cancer management are jaundice management, vascular resection and neo-adjuvant therapy. Preoperative biliary drainage is re...

journal_title：World journal of gastroenterology

authors： Alamo JM,Marín LM,Suarez G,Bernal C,Serrano J,Barrera L,Gómez MA,Muntané J,Padillo FJ

更新日期：2014-10-21 00:00:00

abstract：:Acute liver failure is a rare presentation of hematologic malignancy. Acute on chronic liver failure (ACLF) is a newly recognized clinical entity that describes acute hepatic decompensation in persons with preexisting liver disease. Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin's lymphoma (NHL) wi...

journal_title：World journal of gastroenterology

authors： Siba Y,Obiokoye K,Ferstenberg R,Robilotti J,Culpepper-Morgan J

更新日期：2014-11-28 00:00:00

abstract：:INTRODUCTION:To intrestigate the relationship between tumor necrosis factor-alphaand liver fibrosis in patients with chronic liver disease.METHODS:Radioimmunoassay was made in 20 patients with mild chronic hepatitis(CMH),20 patients with severe chronic hepatitis(CSH),51 patients with liver cirrhosis(LC)and 32-normal p...

journal_title：World journal of gastroenterology

authors： Wang X,Chen YX,Xu CF,Zhao GN,Huang YX,Wang QL

更新日期：1998-02-01 00:00:00

abstract：AIM:To investigate the optimum period of treatment for post endoscopic submucosal dissection (ESD) ulcers. METHODS:Patients who underwent ESD for gastric cancer were randomized to two groups and treated with esomeprazole 20 mg per day for 4 wk (4W group) or 2 wk (2W group). At 4 wk after ESD, we measured the size of t...

journal_title：World journal of gastroenterology

authors： Arai M,Matsumura T,Okimoto K,Oyamada A,Saito K,Minemura S,Maruoka D,Tanaka T,Nakagawa T,Katsuno T,Yokosuka O

更新日期：2014-11-21 00:00:00

abstract：AIM:The significance of hepatitis C virus (HCV) serum titers has been examined in several clinical situations. There is much evidence that patients with a lower viral load have better response rates to anti-viral therapy compared to those with higher levels. Moreover, a direct association has been observed between seru...

journal_title：World journal of gastroenterology

authors： Anand BS,Velez M

更新日期：2004-08-15 00:00:00

abstract：AIM:To identify predictors for synchronous liver metastasis from resectable pancreatic ductal adenocarcinoma (PDAC) and assess unresectability of synchronous liver metastasis. METHODS:Retrospective records of PDAC patients with synchronous liver metastasis who underwent simultaneous resections of primary PDAC and sync...

journal_title：World journal of gastroenterology

authors： Shi HJ,Jin C,Fu DL

更新日期：2016-12-07 00:00:00

abstract：:We report a case of severe thrombocytopenia following pegylated interferon-alpha 2a (Peg-IFN-alpha 2a) treatment of hepatitis C virus infection and summarize the clinical characteristics of 16 cases of IFN-alpha induced severe thrombocytopenia and its immune-mediated mechanism. Discontinuation of IFN-alpha and early a...

journal_title：World journal of gastroenterology

authors： Li L,Han DK,Lu J

更新日期：2010-03-21 00:00:00

abstract：AIM:To study the outcome of patients undergoing surgical resection of the bowel for sustained radiation-induced damage intractable to conservative management. METHODS:During a 7-year period we operated on 17 cases (5 male, 12 female) admitted to our surgical department with intestinal radiation injury (IRI). They were...

journal_title：World journal of gastroenterology

authors： Perrakis N,Athanassiou E,Vamvakopoulou D,Kyriazi M,Kappos H,Vamvakopoulos NC,Nomikos I

更新日期：2011-09-21 00:00:00

abstract：BACKGROUND:Esophagomediastinal fistula is a very rare complication of tuberculosis in otherwise healthy adults, and mediastinal bronchial artery aneurysm is even rarer. In this case report, we describe a rare case of tuberculosis complication that presented with acute upper gastrointestinal (GI) bleeding. It also highl...

journal_title：World journal of gastroenterology

authors： Alharbi SR

更新日期：2019-05-07 00:00:00