Two-week treatment with proton pump inhibitor is sufficient for healing post endoscopic submucosal dissection ulcers.

abstract：AIM:To determine short- and long-term outcomes of endoscopic submucosal dissection (ESD) using the stag beetle (SB) knife, a scissor-shaped device. METHODS:Seventy consecutive patients with 96 early esophageal neoplasms, who underwent ESD using a SB knife at Kure Medical Center and Chugoku Cancer Center, Japan, betwee...

journal_title：World journal of gastroenterology

authors： Kuwai T,Yamaguchi T,Imagawa H,Miura R,Sumida Y,Takasago T,Miyasako Y,Nishimura T,Iio S,Yamaguchi A,Kouno H,Kohno H,Ishaq S

更新日期：2018-04-21 00:00:00

abstract：AIM:To characterise the viral kinetics of enterovirus 71 (EV71). METHODS:In this study, human rhabdomyosarcoma (RD) cells were infected with EV71 at different multiplicity of infection (MOI). After infection, the cytopathic effect (CPE) was monitored and recorded using a phase contrast microscope associated with a CCD...

journal_title：World journal of gastroenterology

authors： Lu J,He YQ,Yi LN,Zan H,Kung HF,He ML

更新日期：2011-09-28 00:00:00

abstract：:Castleman's disease (CD) is a rare lymphoproliferative disorder of unknown etiology. Clinically, it occurs as a localized (unicentric) disease or as a systemic (multicentric) disease. Unicentric Castleman's disease (UCD) presents as a solitary mass and primarily affects the mediastinal, retroperitoneal, and cervical l...

journal_title：World journal of gastroenterology

authors： Lee HJ,Jeon HJ,Park SG,Park CY

更新日期：2015-02-07 00:00:00

abstract：AIM:To study the effect of hepatitis C virus nonstructural protein 3 c-terminal deleted protein (HCV NS3-5') on hepatocyte transformation and tumor development. METHODS:QSG7701 cells were transfected with plasmid pRcHCNS3-5' (expressing HCV NS3 c-terminal deleted protein) by lipofectamine and selected in G418. The exp...

journal_title：World journal of gastroenterology

authors： He QQ,Cheng RX,Sun Y,Feng DY,Chen ZC,Zheng H

更新日期：2003-03-01 00:00:00

abstract：:The origin of inflammatory bowel disease is unknown. Attempts have been made to isolate a microorganism that could explain the onset of inflammation, but no pathological agent has ever been identified. Johne's disease is a granulomatous chronic enteritis of cattle and sheep caused by Mycobacterium avium subspecies par...

journal_title：World journal of gastroenterology

authors： Liverani E,Scaioli E,Cardamone C,Dal Monte P,Belluzzi A

更新日期：2014-09-28 00:00:00

abstract：AIM:To identify the differentially over-expressed genes associated with β-catenin accumulation in nuclei of hepatocellular carcinoma (HCC) cells. METHODS:Differentially expressed genes were identified in radiation-induced B6C3 F1 mouse HCC cells by mRNA differential display, Northern blot and RT-PCR, respectively. Tot...

journal_title：World journal of gastroenterology

authors： Li YS,Liu M,Nakata Y,Tang HB

更新日期：2011-04-07 00:00:00

abstract：AIM:To investigate the effect of Clostridium difficile (C. difficile) infection in an interleukin 10-deficient (IL-10(-/-)) mouse model of inflammatory bowel disease. METHODS:Bone marrow-derived dendritic cells isolated from wild type (WT) and IL-10(-/-)mice were stimulated for 4 h with C. difficile toxin A (200 μg/mL...

journal_title：World journal of gastroenterology

authors： Kim MN,Koh SJ,Kim JM,Im JP,Jung HC,Kim JS

更新日期：2014-12-07 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the major causes of morbidity and mortality in patients with chronic liver disease. Transarterial chemoembolization (TACE) can significantly improve the survival rate of patients with HCC and is the first treatment choice for patients who are not suitable for surgical resection...

journal_title：World journal of gastroenterology

authors： Yang K,Zhang XM,Yang L,Xu H,Peng J

更新日期：2016-05-28 00:00:00

abstract：BACKGROUND:Progressive familial intrahepatic cholestasis (PFIC) encompasses a group of autosomal recessive disorders with high morbidity and mortality. Variants in the gene encoding tight junction protein-2 (TJP2) have been linked to PFIC type 4 (PFIC4), which predominantly presents in childhood. However, there are onl...

journal_title：World journal of gastroenterology

authors： Wei CS,Becher N,Friis JB,Ott P,Vogel I,Grønbæk H

更新日期：2020-02-07 00:00:00

abstract：AIM:To investigate biogenesis and intracellular localizations of clusterin to elucidate the potential molecular mechanisms implicated in tumorigenesis of esophageal mucosa. METHODS:Semi-quantitative RT-PCR for multi-region alteration analysis, Western blot for different transcriptional forms and immunohistochemical st...

journal_title：World journal of gastroenterology

authors： He HZ,Song ZM,Wang K,Teng LH,Liu F,Mao YS,Lu N,Zhang SZ,Wu M,Zhao XH

更新日期：2004-05-15 00:00:00

abstract：AIM:To observe the preventive effects of combined therapy of AMD (allantoin, metronidazolem and dexamethasone in combination) on intra-abdominal adhesion in dogs. METHODS:20 dogs of both sexes were used in this study. After laparotomy under anesthesia, 2 cm section of cecal end was clamped and ligated, then 1 cm cecum...

journal_title：World journal of gastroenterology

authors： Wang XC,Gui CQ,Zheng QS

更新日期：2003-03-01 00:00:00

abstract：AIM:To investigate the prognostic value of the model for end-stage liver disease (MELD) and three new MELD-based models combination with serum sodium in decompensated cirrhosis patients-the MELD with the incorporation of serum sodium (MELD-Na), the integrated MELD (iMELD), and the MELD to sodium (MESO) index. METHODS:...

journal_title：World journal of gastroenterology

authors： Jiang M,Liu F,Xiong WJ,Zhong L,Chen XM

更新日期：2008-11-14 00:00:00

abstract：:Folate deficiency and its association with cancer have been studied in the literature, but its clinical impact is still unknown. Folate deficiency and its result on gastric cancer is a mysterious part of oncology, with ongoing studies hopefully clarifying its impact on gastric cancer management. Lee et al studied fola...

journal_title：World journal of gastroenterology

authors： Alkan A,Mızrak D,Utkan G

更新日期：2015-04-07 00:00:00

abstract：AIM:To investigate the role of pre-core and basal core promoter (BCP) mutations before and after hepatitis B e antigen (HBeAg) seroconversion. METHODS:The proportion of pre-core (G1896A) and basal core promoter (A1762T and G1764A) mutant viruses and serum levels of hepatitis B virus (HBV) DNA, hepatitis B surface anti...

journal_title：World journal of gastroenterology

authors： Kamijo N,Matsumoto A,Umemura T,Shibata S,Ichikawa Y,Kimura T,Komatsu M,Tanaka E

更新日期：2015-01-14 00:00:00

abstract：:Data from genome wide association studies and geoepidemiological studies established that a combination of genetic predisposition and environmental stimulation is required for the loss of tolerance in primary biliary cholangitis (PBC). The serologic hallmark of PBC are the presence of high titer anti-mitochondrial aut...

journal_title：World journal of gastroenterology

authors： Wang J,Yang G,Dubrovsky AM,Choi J,Leung PS

更新日期：2016-01-07 00:00:00

abstract：:Hypertriglyceridemic pancreatitis (HTGP) accounts for up to 10% of acute pancreatitis presentations in non-pregnant individuals and is the third most common cause of acute pancreatitis after alcohol and gallstones. There are a number of retrospective studies and case reports that have suggested a role for apheresis an...

journal_title：World journal of gastroenterology

authors： Saleh MA,Mansoor E,Cooper GS

更新日期：2017-10-28 00:00:00

abstract：AIM:To characterize the protein files in blood from same patients with esophageal squamous cell carcinoma (ESCC) before and after operation at the high-incidence area for ESCC in Henan Province, China. METHODS:Two-dimensional electrophoresis, silver staining and ImageMaster 2-DE analysis software were applied to the d...

journal_title：World journal of gastroenterology

authors： An JY,Fan ZM,Zhuang ZH,Qin YR,Gao SS,Li JL,Wang LD

更新日期：2004-11-15 00:00:00

abstract：AIM:To unravel the differences between systematic inflammatory response syndrome (SIRS) of acute pancreatitis compared to the same syndrome in sepsis. METHODS:Twenty-five patients were enrolled, 12 with sepsis and 13 acute pancreatitis. After diagnosis 20 mL blood was sampled. Half were assayed for isolation of monocy...

journal_title：World journal of gastroenterology

authors： Koussoulas V,Tzivras M,Karagianni V,Spyridaki E,Plachouras D,Giamarellou H,Giamarellos-Bourboulis EJ

更新日期：2006-11-07 00:00:00

abstract：AIM:To explore the effects of peptide S-8300 from shark liver (S-8300) on liver function as well as in regulating immune functions in experimental injury models. METHODS:Mice were administered with different doses of S-8300 for four consecutive days, followed by mice injected with tetrachloromethane (CCl(4)) on d 3. T...

journal_title：World journal of gastroenterology

authors： Huang FJ,Lv ZB,Li Q,Wei LJ,Zhang L,Wu WT

更新日期：2005-03-28 00:00:00

abstract：AIM:To investigate markers for high-grade dysplasia for the optimal timing of liver transplantation in patients with primary sclerosing cholangitis (PSC). METHODS:Earlier data support a dysplasia-carcinoma sequence, even low- to high-grade dysplasia, in PSC-associated cholangiocarcinoma (CCA). Surveillance using endos...

journal_title：World journal of gastroenterology

authors： Boyd S,Vannas M,Jokelainen K,Isoniemi H,Mäkisalo H,Färkkilä MA,Arola J

更新日期：2017-09-07 00:00:00

abstract：:High-throughput short-read sequencing of exomes and whole cancer genomes in multiple human hepatocellular carcinoma (HCC) cohorts confirmed previously identified frequently mutated somatic genes, such as TP53, CTNNB1 and AXIN1, and identified several novel genes with moderate mutation frequencies, including ARID1A, AR...

journal_title：World journal of gastroenterology

authors： Gu DL,Chen YH,Shih JH,Lin CH,Jou YS,Chen CF

更新日期：2013-12-21 00:00:00

abstract：AIM:To introduce the combination method of radiochemoembolization for the treatment of selected hepatic metastases. METHODS:Twenty patients with biopsy proven hepatic metastases were selected from those who underwent transarterial radiochemoembolization, a novel combination protocol, between January 2009 and July 2010...

journal_title：World journal of gastroenterology

authors： Akhlaghpoor S,Aziz-Ahari A,Amoui M,Tolooee S,Poorbeigi H,Sheybani S

更新日期：2012-10-07 00:00:00

abstract：:A 76-year-old woman with a 5-mo history of recurrent diarrhea and generalized edema was admitted to our hospital. Colonoscopy revealed edematous mucosa, and histopathological examination was compatible with collagenous colitis. Protein leakage from the colon, particularly in the ascending portion, was identified on 99...

journal_title：World journal of gastroenterology

authors： Sano S,Yamagami K,Tanaka A,Nishio M,Nakamura T,Kubo Y,Inoue T,Ueda W,Okawa K,Yoshioka K

更新日期：2008-10-21 00:00:00

abstract：AIM:To investigate the effect of APOBEC3G mediated antiviral activity against hepatitis B virus (HBV) in cell cultures and replication competent HBV vector-based mouse model. METHODS:The mammalian hepatoma cells Huh7 and HepG2 were cotransfected with various amounts of CMV-driven expression vector encoding APOBEC3G an...

journal_title：World journal of gastroenterology

authors： Lei YC,Hao YH,Zhang ZM,Tian YJ,Wang BJ,Yang Y,Zhao XP,Lu MJ,Gong FL,Yang DL

更新日期：2006-07-28 00:00:00

abstract：AIM:To investigate the effect of a fat rich diet on non-steroidal anti-inflammatory drug (NSAID)-induced mucosal damage in the murine small intestine. METHODS:C57BL6 mice were fed 4 types of diets with or without indomethacin. One group was fed standard laboratory chow. The other groups were fed a fat diet consisting ...

journal_title：World journal of gastroenterology

authors： Ueda T,Hokari R,Higashiyama M,Yasutake Y,Maruta K,Kurihara C,Tomita K,Komoto S,Okada Y,Watanabe C,Usui S,Nagao S,Miura S

更新日期：2015-01-07 00:00:00

abstract：AIM:To examine whether a dose-up to 900 mg of ursodeoxycholic acid (UDCA) decreases transaminases in hepatitis C patients. METHODS:From January to December 2007, patients with chronic hepatitis C or compensated liver cirrhosis with hepatitis C virus (HCV) (43-80 years old) showing positive serum HCV-RNA who had alread...

journal_title：World journal of gastroenterology

authors： Sato S,Miyake T,Tobita H,Oshima N,Ishine J,Hanaoka T,Amano Y,Kinoshita Y

更新日期：2009-06-14 00:00:00

abstract：:Neurofibromas of the large bowel are very rare and usually are part of the colonic involvement in neurofibromatosis type 1 (Nf1, von Recklinghausen's disease). Solitary neurofibromas of the colon are extremely rare. We describe a case of an isolated neurofibroma that was found in the large bowel of a patient who suffe...

journal_title：World journal of gastroenterology

authors： Panteris V,Vassilakaki T,Vaitsis N,Elemenoglou I,Mylonakou I,Karamanolis DG

更新日期：2005-09-21 00:00:00

abstract：AIM:To assess the effectiveness of endoscopic full-thickness resection (EFR) and laparoscopic surgery in the treatment of gastric stromal tumors arising from the muscularis propria. METHODS:Out of 62 gastric stromal tumors arising from the muscularis propria, each > 1.5 cm in diameter, 32 were removed by EFR, and 30 w...

journal_title：World journal of gastroenterology

authors： Huang LY,Cui J,Wu CR,Zhang B,Jiang LX,Xian XS,Lin SJ,Xu N,Cao XL,Wang ZH

更新日期：2014-07-07 00:00:00

abstract：AIM:To characterize the biochemical and immunological properties of an experimental ISCOMS vaccine prepared from a novel therapeutic polypeptide based on T cell epitopes of HBsAg, and a heptatis B-ISCOMS was prepared and investigated. METHODS:An immunostimulating complexes(ISCOMS)-based vaccine containing a novel ther...

journal_title：World journal of gastroenterology

authors： Guan XJ,Guan XJ,Wu YZ,Jia ZC,Shi TD,Tang Y

更新日期：2002-04-01 00:00:00

abstract：:We report an extremely rare case where a mesenchymal differentiation, especially embryonal sarcoma, was demonstrated in cholangiocarcinoma. At autopsy, a yellowish-white tumor (15 cm x 12 cm) was found in the right hepatic lobe, and there were several daughter nodules in both hepatic lobes. Histologically, most of the...

journal_title：World journal of gastroenterology

authors： Sumiyoshi S,Kikuyama M,Matsubayashi Y,Kageyama F,Ide Y,Kobayashi Y,Nakamura H

更新日期：2007-02-07 00:00:00