Advanced imaging techniques in the therapeutic response of transarterial chemoembolization for hepatocellular carcinoma.

Abstract:

:Hepatocellular carcinoma (HCC) is one of the major causes of morbidity and mortality in patients with chronic liver disease. Transarterial chemoembolization (TACE) can significantly improve the survival rate of patients with HCC and is the first treatment choice for patients who are not suitable for surgical resections. The evaluation of the response to TACE treatment affects not only the assessment of the therapy efficacy but also the development of the next step in the treatment plan. The use of imaging to examine changes in tumor volume to assess the response of solid tumors to treatment has been controversial. In recent years, the emergence of new imaging technology has made it possible to observe the response of tumors to treatment prior to any morphological changes. In this article, the advances in studies reporting the use of computed tomography perfusion imaging, diffusion-weighted magnetic resonance imaging (MRI), intravoxel incoherent motion, diffusion kurtosis imaging, magnetic resonance spectroscopy, magnetic resonance perfusion-weighted imaging, blood oxygen level-dependent MRI, positron emission tomography (PET)/computed tomography and PET/MRI to assess the TACE treatment response are reviewed.

journal_name

World J Gastroenterol

authors

Yang K,Zhang XM,Yang L,Xu H,Peng J

doi

10.3748/wjg.v22.i20.4835

subject

Has Abstract

pub_date

2016-05-28 00:00:00

pages

4835-47

issue

20

eissn

1007-9327

issn

2219-2840

journal_volume

22

pub_type

杂志文章,评审
  • Reduced antioxidant level and increased oxidative damage in intact liver lobes during ischaemia-reperfusion.

    abstract:AIM:To determine whether increased blood flow of the liver can cause oxidative stress and hepatocyte damage, and to elaborate methods suitable for measuring the antioxidant defence during hepatic surgery on rat model. METHODS:In nembutal narcosis, the left lateral and the medial lobes of the liver were clipped for 45 ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i7.1086

    authors: Váli L,Taba G,Szentmihályi K,Fébel H,Kurucz T,Pallai Z,Kupcsulik P,Blázovics A

    更新日期:2006-02-21 00:00:00

  • Synergistic effects of interferon-alpha in combination with chemoradiation on human pancreatic adenocarcinoma.

    abstract:AIM:To determine whether IFN-alpha is the agent that turns a slightly effective treatment (radiochemotherapy) into a potent therapy, we tested IFN-alpha for its synergistic properties. METHODS:Eight pancreatic carcinoma cell lines were treated with the single agents and combinations of these. The role of IFN-alpha reg...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i10.1521

    authors: Ma JH,Patrut E,Schmidt J,Knaebel HP,Büchler MW,Märten A

    更新日期:2005-03-14 00:00:00

  • Surveillance for hepatocellular carcinoma in chronic liver disease: evidence and controversies.

    abstract::Primary liver cancer is the sixth most common cancer in the world and the third cause of cancer-related death. Hepatocellular carcinoma (HCC) represents more than 90% of primary liver cancers and generally occurs in patients with underlying chronic liver disease such as viral hepatitis, hemochromatosis, primary biliar...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v19.i40.6744

    authors: van Meer S,de Man RA,Siersema PD,van Erpecum KJ

    更新日期:2013-10-28 00:00:00

  • Role of three-dimensional endoanal ultrasound in assessing the anal sphincter morphology of female patients with chronic proctalgia.

    abstract:AIM:To assess the role of three-dimensional endoanal ultrasound (3D-EAUS) for morphological assessment of the anal sphincter of female patients with chronic proctalgia (CP). METHODS:In this unmatched case control study, 30 consecutive female patients with CP and 25 normal women (control group) were enrolled. 3D-EAUS w...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i21.3900

    authors: Xue YH,Ding SQ,Ding YJ,Pan LQ

    更新日期:2017-06-07 00:00:00

  • Therapeutic proteasome inhibition in experimental acute pancreatitis.

    abstract:AIM:To establish the therapeutic potential of proteasome inhibition, we examined the therapeutic effects of MG132 (Z-Leu-Leu-Leu-aldehyde) in an experimental model of acute pancreatitis. METHODS:Pancreatitis was induced in rats by two hourly intraperitoneal (ip) injections of cholecystokinin octapeptide (CCK; 2 x 100 ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i33.4452

    authors: Letoha T,Fehér LZ,Pecze L,Somlai C,Varga I,Kaszaki J,Tóth G,Vizler C,Tiszlavicz L,Takács T

    更新日期:2007-09-07 00:00:00

  • Contribution of mammalian target of rapamycin in the pathophysiology of cirrhotic cardiomyopathy.

    abstract:AIM:To explore the role of mammalian target of rapamycin (mTOR) in the pathogenesis of cirrhotic cardiomyopathy and the potential of rapamycin to improve this pathologic condition. METHODS:Male albino Wistar rats weighing 100-120 g were treated with tetrachloride carbon (CCl4) for 8 wk to induce cirrhosis. Subsequentl...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i19.4685

    authors: Saeedi Saravi SS,Ghazi-Khansari M,Ejtemaei Mehr S,Nobakht M,Mousavi SE,Dehpour AR

    更新日期:2016-05-21 00:00:00

  • Current understanding concerning intestinal stem cells.

    abstract::In mammals, the intestinal epithelium is a tissue that contains two distinct pools of stem cells: active intestinal stem cells and reserve intestinal stem cells. The former are located in the crypt basement membrane and are responsible for maintaining epithelial homeostasis under intact conditions, whereas the latter ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i31.7099

    authors: Cui S,Chang PY

    更新日期:2016-08-21 00:00:00

  • Intensified intensity-modulated radiotherapy in anal cancer with prevalent HPV p16 positivity.

    abstract:AIM:To investigate the toxicity and response of intensity-modulated radiotherapy schedule intensified with a simultaneous integrated boost in anal canal cancer. METHODS:From March 2009 to March 2014, we retrospectively analyzed 41 consecutive patients treated with intensity-modulated radiotherapy (IMRT) and concurrent...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i37.10688

    authors: Belgioia L,Vagge S,Agnese D,Garelli S,Murialdo R,Fornarini G,Chiara S,Gallo F,Bacigalupo A,Corvò R

    更新日期:2015-10-07 00:00:00

  • Total flavone of Abelmoschus manihot suppresses epithelial-mesenchymal transition via interfering transforming growth factor-β1 signaling in Crohn's disease intestinal fibrosis.

    abstract:AIM:To explore the role and mechanism of total flavone of Abelmoschus manihot (TFA) on epithelial-mesenchymal transition (EMT) progress of Crohn's disease (CD) intestinal fibrosis. METHODS:First, CCK-8 assay was performed to assess TFA on the viability of intestinal epithelial (IEC-6) cells and select the optimal conc...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v24.i30.3414

    authors: Yang BL,Zhu P,Li YR,Xu MM,Wang H,Qiao LC,Xu HX,Chen HJ

    更新日期:2018-08-14 00:00:00

  • A case of hypereosinophilic syndrome presenting with intractable gastric ulcers.

    abstract::We report a rare case of hypereosinophilic syndrome (HES) presenting with intractable gastric ulcers. A 71-year-old man was admitted with epigastric pain. Initial endoscopic findings revealed multiple, active gastric ulcers in the gastric antrum. He underwent Helicobacter pylori (H pylori) eradication therapy followed...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.15.6129

    authors: Park TY,Choi CH,Yang SY,Oh IS,Song ID,Lee HW,Kim HJ,Do JH,Chang SK,Cho AR,Cha YJ

    更新日期:2009-12-28 00:00:00

  • Effect of alcohol consumption on liver stiffness measured by transient elastography.

    abstract:AIM:To determine the evolution of transient elastography (TE) in patients with alcoholic liver disease according to alcohol cessation or continuation. METHODS:We retrospectively selected in our local database all patients who had two TE between June 2005 and November 2010 with chronic alcohol excessive consumption and...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i4.516

    authors: Bardou-Jacquet E,Legros L,Soro D,Latournerie M,Guillygomarc'h A,Le Lan C,Brissot P,Guyader D,Moirand R

    更新日期:2013-01-28 00:00:00

  • Single nucleotide polymorphisms in the CDH17 gene of colorectal carcinoma.

    abstract:AIM:To investigate the relationship between c.343A>G and c.2216A>C polymorphism sites in the CDH17 gene and colorectal carcinoma. METHODS:Ninety-three non-consanguineous colorectal carcinoma patients admitted to the Department of Oncology at the First Affiliated Hospital of Zhengzhou University were included in this s...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i48.7251

    authors: Chen RY,Cao JJ,Chen J,Yang JP,Liu XB,Zhao GQ,Zhang YF

    更新日期:2012-12-28 00:00:00

  • Role of cenicriviroc in the management of nonalcoholic fatty liver disease.

    abstract::Nonalcoholic fatty liver disease (NAFLD) is the commonest chronic liver disease in high-income countries and is associated with increased morbidity and mortality. Macrophages appear to play an important role in the development and progression of hepatic fibrosis in patients with NAFLD. Accordingly, modulation of macro...

    journal_title:World journal of gastroenterology

    pub_type: 社论

    doi:10.3748/wjg.v24.i48.5415

    authors: Neokosmidis G,Tziomalos K

    更新日期:2018-12-28 00:00:00

  • Do the expressions of gap junction gene connexin messenger RNA in noncancerous liver remnants of patients with hepatocellular carcinoma correlate with postoperative recurrences?

    abstract:AIM:To investigate whether the changes of gap junction gene connexin messenger RNA in the noncancerous liver tissue of patients with hepatocellular carcinoma (HCC) could play a significant role in its postresection recurrence. METHODS:Seventy-nine consecutive patients having undergone curative resection for HCC entere...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i2.171

    authors: Sheen IS,Jeng KS,Shih SC,Kao CR,Wang PC,Chen CZ,Chang WH,Wang HY,Shyung LR

    更新日期:2005-01-14 00:00:00

  • alpha,beta-amyrin, a natural triterpenoid ameliorates L-arginine-induced acute pancreatitis in rats.

    abstract:AIM:To study the beneficial effects of triterpene alpha,beta-amyrin and the underlying mechanisms in an experimental pancreatitis model. METHODS:Acute pancreatitis was induced in five groups of rats (n = 8) by L-arginine (2 x 2.5 g/kg, intraperitoneal, 1 h apart) and 1 h later, they received a single oral dose of alph...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i34.4272

    authors: Melo CM,Carvalho KM,Neves JC,Morais TC,Rao VS,Santos FA,Brito GA,Chaves MH

    更新日期:2010-09-14 00:00:00

  • Eradication of Helicobacter pylori infection: which regimen first?

    abstract::Helicobacter pylori (H. pylori) is a well-known human pathogen that plays an essential role in the pathogenesis of chronic gastritis, peptic ulcer disease, and gastric malignancies. Although H. pylori is susceptible to several antimicrobials, this infection has proven challenging to cure because of the increasing prev...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i3.665

    authors: Federico A,Gravina AG,Miranda A,Loguercio C,Romano M

    更新日期:2014-01-21 00:00:00

  • Common bile duct obstruction due to fibrous pseudotumor of pancreas associated with retroperitoneal fibrosis: a case report.

    abstract::One 63-year-old woman, who presented with cholestatic jaundice due to common bile duct compression produced by primary retroperitoneal fibrosis, is studied. The patient was operated six years ago because of hydronephrosis, when the disease was first diagnosed. Magnetic resonance cholangiopancreatography (MRCP) reveale...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i20.3078

    authors: Zhao MF,Tian Y,Guo KJ,Ma ZG,Liao HH

    更新日期:2004-10-15 00:00:00

  • Effects of tetrandrine on gastric mucosa and liver in portal hypertensive rats.

    abstract:AIM:To study the effects of tetrandrine on portal hypertensive gastric mucosal lesions. METHODS:Portal hypertensive models were induced in Wistar rats by 60% CCl4 3 mL/kg body weight through subcutaneous injection, once every 4 d for 56 d. The animals were randomly divided into portal hypertension, tetrandrine and pro...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v3.i3.192

    authors: Mu Y,Shen YZ,Chu YF

    更新日期:1997-09-15 00:00:00

  • Effects of glutamine on intestinal permeability and bacterial translocation in TPN-rats with endotoxemia.

    abstract:AIM:To evaluate the protective effect and mechanism of glutamine on the intestinal barrier function in total parenteral nutrition (TPN) rats with trauma or endotoxemia. METHODS:To perform prospective, randomized and controlled animal experimentation of rats with surgical trauma, TPN and endotoxemia, thirty-four male, ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i6.1327

    authors: Ding LA,Li JS

    更新日期:2003-06-01 00:00:00

  • siRNA targeting of Cdx2 inhibits growth of human gastric cancer MGC-803 cells.

    abstract:AIM:To investigate the effects of small interference RNA (siRNA) targeting of Cdx2 on human gastric cancer MGC-803 cells in vitro and in vivo. METHODS:The recombinant pSilencer 4.1-Cdx2 siRNA plasmids were constructed and transfected into gastric cancer MGC-803 cells in vitro. The stable transfectants were selected. T...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i16.1903

    authors: Wang XT,Xie YB,Xiao Q

    更新日期:2012-04-28 00:00:00

  • Down-regulation of Hsp90 could change cell cycle distribution and increase drug sensitivity of tumor cells.

    abstract::AIM:To construct Hsp90 antisense RNA eukaryotic expression vector, transfect it into SGC7901 and SGC7901/VCR of MDR-type human gastric cancer cell lines, HCC7402 of human hepatic cancer and Ec109 of human esophageal cancer cell lines, and to study the cell cycle distribution of the gene transected cells and their resp...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v5.i3.199

    authors: Liu XL,Xiao B,Yu ZC,Guo JC,Zhao QC,Xu L,Shi YQ,Fan DM

    更新日期:1999-06-01 00:00:00

  • Vanishing bile duct syndrome in Hodgkin's lymphoma: A case report and literature review.

    abstract::Vanishing bile duct syndrome (VBDS) has been described in different pathologic conditions including infection, ischemia, adverse drug reactions, autoimmune diseases, allograft rejection, and humoral factors associated with malignancy. It is an acquired condition characterized by progressive destruction and loss of the...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v23.i2.366

    authors: Bakhit M,McCarty TR,Park S,Njei B,Cho M,Karagozian R,Liapakis A

    更新日期:2017-01-14 00:00:00

  • Anemia after gastrectomy for early gastric cancer: long-term follow-up observational study.

    abstract:AIM:To identify the incidence and etiology of anemia after gastrectomy in patients with long-term follow-up after gastrectomy for early gastric cancer. METHODS:The medical records of those patients with early gastric adenocarcinoma who underwent curative gastrectomy between January 2006 and October 2007 were reviewed....

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i42.6114

    authors: Lim CH,Kim SW,Kim WC,Kim JS,Cho YK,Park JM,Lee IS,Choi MG,Song KY,Jeon HM,Park CH

    更新日期:2012-11-14 00:00:00

  • Linc00675 is a novel marker of short survival and recurrence in patients with pancreatic ductal adenocarcinoma.

    abstract:AIM:To detect linc00675 expression in pancreatic ductal adenocarcinoma (PDAC), to analyze the relationship between the expression level of linc00675 and the clinical pathological characteristics, to explore the biological functions of linc00675, and to determine whether linc00675 has independent prognostic value in PDA...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i31.9348

    authors: Li DD,Fu ZQ,Lin Q,Zhou Y,Zhou QB,Li ZH,Tan LP,Chen RF,Liu YM

    更新日期:2015-08-21 00:00:00

  • Intraductal papillary mucinous carcinoma with atypical manifestations: report of two cases.

    abstract::Intraductal papillary mucinous neoplasms (IPMNs) are a well-characterized group of mucin-producing cystic neoplasms of the clear malignant potential type. We report here two cases of intraductal papillary mucinous carcinoma (IPMC) with atypical manifestations. In one case, we discussed a pseudomyxoma peritonei caused ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i10.1622

    authors: Lee SE,Jang JY,Yang SH,Kim SW

    更新日期:2007-03-14 00:00:00

  • Effect of intensive vs conventional insulin therapy on perioperative nutritional substrates metabolism in patients undergoing gastrectomy.

    abstract:AIM:To investigate the effect of intensive vs conventional insulin therapy on perioperative nutritional substrates metabolism in patients undergoing radical distal gastrectomy. METHODS:Within 24 h of intensive care unit management, patients with gastric cancer were enrolled after written informed consent and randomize...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3748/wjg.v18.i21.2695

    authors: Liu HC,Zhou YB,Chen D,Niu ZJ,Yu Y

    更新日期:2012-06-07 00:00:00

  • Influence of continuous veno-venous hemofiltration on the course of acute pancreatitis.

    abstract:AIM:To investigate whether continuous veno-venous hemofiltration (CVVH) in different filtration rate to eliminate cytokines would result in different efficiency in acute pancreatitis, whether the saturation time of filter membrane was related to different filtration rate, and whether the onset time of CVVH could influe...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3748/wjg.v11.i31.4815

    authors: Jiang HL,Xue WJ,Li DQ,Yin AP,Xin X,Li CM,Gao JL

    更新日期:2005-08-21 00:00:00

  • Methodology for high-quality studies on course and prognosis of inflammatory bowel disease.

    abstract::Inflammatory bowel diseases (IBDs) are characterized by a chronic course with an alternation of relapses and remissions. Questions about prognosis are important for the patient who wants to know how the disease will affect his/her life and also for clinicians to make management decisions. Correct selection of the pati...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v18.i29.3800

    authors: Modesto I,Perricone G,Orlando A,Cottone M

    更新日期:2012-08-07 00:00:00

  • Idiopathic neonatal pneumoperitoneum with favorable outcome: A case report and review.

    abstract::Neonatal pneumoperitoneum is a surgical emergency indicative of gastrointestinal perforation that requires immediate treatment to prevent death. There have been non-surgical conditions secondary to neonatal pneumoperitoneum (e.g., mechanical ventilation, pulmonary diseases and pneumatosis cystoides intestinalis) that ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v21.i20.6417

    authors: He TZ,Xu C,Ji Y,Sun XY,Liu M

    更新日期:2015-05-28 00:00:00

  • Value of α-fetoprotein in association with clinicopathological features of hepatocellular carcinoma.

    abstract:AIM:To explore the relationship between α-fetoprotein (AFP) and various clinicopathological variables and different staging system of hepatocellular carcinoma (HCC) thoroughly. METHODS:A retrospective cohort study of consecutive patients diagnosed with HCC between January 2008 and December 2009 in West China Hospital ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i11.1811

    authors: Liu C,Xiao GQ,Yan LN,Li B,Jiang L,Wen TF,Wang WT,Xu MQ,Yang JY

    更新日期:2013-03-21 00:00:00