Beta-7 integrin controls enterocyte migration in the small intestine.

abstract：:According to the main international clinical guidelines, the recommended treatment for locally-advanced rectal cancer is neoadjuvant chemoradiotherapy followed by surgery. However, doubts have been raised about the appropriate definition of clinical complete response (cCR) after neoadjuvant therapy and the role of sur...

journal_title：World journal of gastroenterology

authors： López-Campos F,Martín-Martín M,Fornell-Pérez R,García-Pérez JC,Die-Trill J,Fuentes-Mateos R,López-Durán S,Domínguez-Rullán J,Ferreiro R,Riquelme-Oliveira A,Hervás-Morón A,Couñago F

更新日期：2020-08-07 00:00:00

abstract：AIM:To evaluate the efficacy and safety of a hybrid bioartificial liver (HBAL) system in the treatment of acute liver failure. METHODS:Canine models with acute liver failure were introduced with intravenous administration of D-galactosamine. The animals were divided into: the HBAL treatment group (n = 8), in which the...

journal_title：World journal of gastroenterology

authors： Shi XL,Zhang Y,Chu XH,Han B,Gu JY,Xiao JQ,Tan JJ,Gu ZZ,Ren HZ,Yuan XW,Ding YT

更新日期：2012-07-28 00:00:00

abstract：:Neuroendocrine carcinoma (NEC) of the gallbladder is a rare subtype of gallbladder tumor. Here, we report two cases of NEC in two patients initially suspected to have gallbladder carcinoma. No specific symptoms or abnormal blood test results were observed preoperatively. Abdominal computed tomography scans indicated i...

journal_title：World journal of gastroenterology

authors： Chen H,Shen YY,Ni XZ

更新日期：2014-09-07 00:00:00

abstract：AIM:To elucidate the relationship between the microvessel count (MVC) by CD34 analyzed by immunohistochemical method and prognosis in hepatocellular carcinoma (HCC) patients who underwent hepatectomy based on our preliminary study. METHODS:We examined relationships between MVC and clinicopathological factors in 128 HC...

journal_title：World journal of gastroenterology

authors： Nanashima A,Nakayama T,Sumida Y,Abo T,Takeshita H,Shibata K,Hidaka S,Sawai T,Yasutake T,Nagayasu T

更新日期：2008-08-21 00:00:00

abstract：AIM:To investigate the possible involvement of 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase [1alpha-25(OH) (2) D(3)] in butyrate-induced differentiation in human intestinal cell line Caco-2 cells. METHODS:Caco-2 cells were incubated either with 3 mmol/L butyrate and 1 micromol/L 25(OH) (2) D(3) or with 1 micromol/L 1al...

journal_title：World journal of gastroenterology

authors： Schröder O,Turak S,Daniel C,Gaschott T,Stein J

更新日期：2005-12-07 00:00:00

abstract：AIM:To determine the association of circulating miR-125a/b expression with the risk and disease severity of Crohn's disease (CD), and with inflammatory cytokines. METHODS:Plasma samples were collected from patients with active CD (A-CD), or CD in remission (R-CD) and from healthy controls (HCs). The levels of the infl...

journal_title：World journal of gastroenterology

authors： Sun CM,Wu J,Zhang H,Shi G,Chen ZT

更新日期：2017-11-28 00:00:00

abstract：AIM:To construct pcDNA3.1-Egr.1p-p16 recombinant plasmid and investigate the expression of p16 in pancreatic cancer JF305 cells induced by radiation and the feasibility of gene radiotherapy for pancreatic carcinoma. METHODS:Human p16 cDNA was ligated to the downstream of Egr-1 promotor to construct pcDNA3.1-Egr.1p-p16...

journal_title：World journal of gastroenterology

authors： Ma HB,Wang XJ,Di ZL,Xia H,Li Z,Liu J,Ma J,Kang HF,Wu CM,Bai MH

更新日期：2007-08-21 00:00:00

abstract：:Ghrelin, as a kind of multifunctional protein polypeptide, is mainly produced in the fundus of the stomach and can promote occurrence and development of many tumors, including gastrointestinal tumors, which has been proved by the relevant researches. Most gastrointestinal stromal tumors (GISTs, about 80%), as the most...

journal_title：World journal of gastroenterology

authors： Zhu CZ,Liu D,Kang WM,Yu JC,Ma ZQ,Ye X,Li K

更新日期：2017-03-14 00:00:00

abstract：AIM:To investigate the efficacy of neoadjuvant chemoradiotherapy (NACRT) for resectability of locally advanced gastric cancer (LAGC). METHODS:Between November 2007 and January 2014, 29 patients with LAGC (clinically T3 with distal esophagus invasion/T4 or bulky regional node metastasis) that were treated with NACRT fo...

journal_title：World journal of gastroenterology

authors： Kim MS,Lim JS,Hyung WJ,Lee YC,Rha SY,Keum KC,Koom WS

更新日期：2015-03-07 00:00:00

abstract：AIM:To investigate the level of nitric oxide (NO) and nitrous oxide synthase (NOS) enzyme and its effect on gastric mucosal pathologic change in patients infected with Helicobacter pylori (H pylori), and to study the pathogenic mechanism of H pylori. METHODS:The mucosal tissues of gastric antrum were taken by endoscop...

journal_title：World journal of gastroenterology

authors： Wang YF,Guo CL,Zhao LZ,Yang GA,Chen P,Wang HK

更新日期：2005-08-28 00:00:00

abstract：:Angiosarcoma is a rare primary malignant neoplasm of the liver with a poor prognosis. Here, we report a case of a patient with a ruptured hepatic angiosarcoma which was treated by emergency catheter-directed embolization, followed by left-sided hemihepatectomy. ...

journal_title：World journal of gastroenterology

authors： Leowardi C,Hormann Y,Hinz U,Wente MN,Hallscheidt P,Flechtenmacher C,Buchler MW,Friess H,Schwarzbach MH

更新日期：2006-02-07 00:00:00

abstract：:It has been known that peripheral adverse event is caused by peripheral antimuscarinic action, from hyoscine butylbromide (Buscopan; Boehringer Ingelheim, Germany) used as a premedication for endoscopy. However, symptoms or signs associated with the central nervous system are rarely reported in the field of anesthesio...

journal_title：World journal of gastroenterology

authors： Lee H,Son HJ,Rhee PL,Kim JJ,Rhee JC

更新日期：2007-07-28 00:00:00

abstract：AIM:To assess numbers and case fatality of patients with upper gastrointestinal bleeding (UGIB), effects of deprivation and whether weekend presentation affected outcomes. METHODS:Data was obtained from Information Services Division (ISD) Scotland and National Records of Scotland (NRS) death records for a ten year per...

journal_title：World journal of gastroenterology

authors： Ahmed A,Armstrong M,Robertson I,Morris AJ,Blatchford O,Stanley AJ

更新日期：2015-10-14 00:00:00

abstract：:Alcoholic fatty liver disease (AFLD), a potentially pathologic condition, can progress to steatohepatitis, fibrosis, and cirrhosis, leading to an increased probability of hepatic failure and death. Alcohol induces fatty liver by increasing the ratio of reduced form of nicotinamide adenine dinucleotide to oxidized form...

journal_title：World journal of gastroenterology

authors： Liu J

更新日期：2014-10-28 00:00:00

abstract：BACKGROUND:Computed tomography (CT), liver stiffness measurement (LSM), and magnetic resonance imaging (MRI) are non-invasive diagnostic methods for esophageal varices (EV) and for the prediction of high-bleeding-risk EV (HREV) in cirrhotic patients. However, the clinical use of these methods is controversial. AIM:To ...

journal_title：World journal of gastroenterology

authors： Li Y,Li L,Weng HL,Liebe R,Ding HG

更新日期：2020-05-14 00:00:00

abstract：:Redox state constitutes an important background of numerous liver disorders. The redox state participates in the course of inflammatory, metabolic and proliferative liver diseases. Reactive oxygen species (ROS) are primarily produced in the mitochondria and in the endoplasmic reticulum of hepatocytes via the cytochrom...

journal_title：World journal of gastroenterology

authors： Cichoż-Lach H,Michalak A

更新日期：2014-07-07 00:00:00

abstract：AIM:To improve anti-inflammatory activity while reducing drug doses, we developed a nanoformulation carrying dexamethasone and butyrate. METHODS:Dexamethasone cholesteryl butyrate-solid lipid nanoparticles (DxCb-SLN) were obtained with the warm microemulsion method. The anti-inflammatory activity of this novel nanofor...

journal_title：World journal of gastroenterology

authors： Dianzani C,Foglietta F,Ferrara B,Rosa AC,Muntoni E,Gasco P,Della Pepa C,Canaparo R,Serpe L

更新日期：2017-06-21 00:00:00

abstract：AIM:To clarify the biological feature contributing to gastric cancer with diffuse bone metastases at diagnosis. METHODS:The participants visited the Department of Clinical Oncology, Akita University Hospital, from January 2014 to August 2015. The selection criterion for gastric cancer with diffuse bone metastases at d...

journal_title：World journal of gastroenterology

authors： Shimazu K,Fukuda K,Yoshida T,Inoue M,Shibata H

更新日期：2016-07-14 00:00:00

abstract：AIM:To examine the potency of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) as a hepatic heme oxygenase-1 (HO-1) inducer and its regulation in HepG2 cells. METHODS:Expression of HO-1 and NF-E2-related factor 2 (Nrf2) and activation of mitogen-activated protein (MAP) kinases were analyzed by Western blot, immunofluore...

journal_title：World journal of gastroenterology

authors： Pae HO,Oh GS,Jeong SO,Jeong GS,Lee BS,Choi BM,Lee HS,Chung HT

更新日期：2006-01-14 00:00:00

abstract：:Liver transplantation has emerged as a life-saving treatment for several patients with acute liver failure, end stage liver disease and primary hepatic malignancies. However, long term immunosuppressive therapy aiming to reduce the risk of transplant rejection increases the incidence of several complications including...

journal_title：World journal of gastroenterology

authors： Dierickx D,Cardinaels N

更新日期：2015-10-21 00:00:00

abstract：AIM:To observe the status of tumor-associated B(7) molecule mRNA expression in human colorectal cancer tissue by in situ hybridization. METHODS:The mRNA expression patterns of cancer-associated B(7-1),B(7)H(1),B(7)H(2),ICOS in 22 specimens of human colorectal cancer tissue were monitored by in situ hybridization (ISH)...

journal_title：World journal of gastroenterology

authors： Xiao JX,Bai PS,Lai BC,Li L,Zhu J,Wang YL

更新日期：2005-09-28 00:00:00

abstract：AIM:To establish the rapid, specific, and sensitive method for detecting O157:H7 with DNA microchips. METHODS:Specific oligonucleotide probes (26-28 nt) of bacterial antigenic and virulent genes of E. coli O157:H7 and other related pathogen genes were pre-synthesized and immobilized on a solid support to make microchi...

journal_title：World journal of gastroenterology

authors： Jin HY,Tao KH,Li YX,Li FQ,Li SQ

更新日期：2005-10-07 00:00:00

abstract：:The incidence of colorectal cancer (CRC) is on the rise, and the prognosis for patients with recurrent or metastatic disease is extremely poor. Although chemotherapy and radiation therapy can improve survival rates, it is imperative to integrate alternative strategies such as immunotherapy to improve outcomes for pati...

journal_title：World journal of gastroenterology

authors： Koido S,Ohkusa T,Homma S,Namiki Y,Takakura K,Saito K,Ito Z,Kobayashi H,Kajihara M,Uchiyama K,Arihiro S,Arakawa H,Okamoto M,Gong J,Tajiri H

更新日期：2013-12-14 00:00:00

abstract：AIM:To evaluate the utility of measuring epigenetic alterations in pancreatic and biliary fluids in determining molecular markers for pancreatobiliary cancers. METHODS:DNA was extracted from undiluted pancreatic and biliary fluids. As a surrogate for a genome-wide hypomethylation assay, levels of long interspersed nuc...

journal_title：World journal of gastroenterology

authors： Kato N,Yamamoto H,Adachi Y,Ohashi H,Taniguchi H,Suzuki H,Nakazawa M,Kaneto H,Sasaki S,Imai K,Shinomura Y

更新日期：2013-03-21 00:00:00

abstract：AIM:To explore molecular mechanism of nicotinamide adenine dinucleotide (NADH) antagonization against X-ray induced L02 cells damage. METHODS:L02 liver cells were cultured in RPMI 1640, exposed to X-ray irradiation and continued to culture in the presence or absence of NADH. Cellular viability was analyzed by routine ...

journal_title：World journal of gastroenterology

authors： Liu FQ,Zhang JR

更新日期：2003-08-01 00:00:00

abstract：AIM:To investigate the role of Delta-like ligand 4 (DLL4) on tumour growth in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) in vivo. METHODS:We suppressed DLL4 expression in an HBV expressing HCC cell line, HepG2.2.15 and analysed the growth ability of cells as subcutaneous tumours in nude mice. Th...

journal_title：World journal of gastroenterology

authors： Kunanopparat A,Issara-Amphorn J,Leelahavanichkul A,Sanpavat A,Patumraj S,Tangkijvanich P,Palaga T,Hirankarn N

更新日期：2018-09-14 00:00:00

abstract：BACKGROUND:Uric acid is the end product of purine metabolism. Previous studies have found that serum uric acid (SUA) levels are associated with the total cancer risk. However, due to the dual effect of uric acid on cancer, the relationship between the SUA levels and most specific-site cancer remains unclear. AIM:To in...

journal_title：World journal of gastroenterology

authors： Huang CF,Huang JJ,Mi NN,Lin YY,He QS,Lu YW,Yue P,Bai B,Zhang JD,Zhang C,Cai T,Fu WK,Gao L,Li X,Yuan JQ,Meng WB

更新日期：2020-11-28 00:00:00

abstract：:It is one of the most important problems for general surgeons to decide which operation should be undertaken on patients with intra-abdominal infection, especially those with concomitant abdominal hypertension. Recently, closure techniques using prosthetic meshes in order to retain abdominal tension and to control sep...

journal_title：World journal of gastroenterology

authors： Tekin S,Tekin A,Kucukkartallar T,Cakir M,Kartal A

更新日期：2008-02-07 00:00:00

abstract：AIM:To investigate the presence of human papillomavirus (HPV) DNA along with the integration, the quantification and the expression of the HPV16 in colorectal cancers. METHODS:A prospective series of colorectal tumors were genotyped for HPV DNA. The clinical and pathological variables of the HPV-positive tumors were c...

journal_title：World journal of gastroenterology

authors： Lorenzon L,Mazzetta F,Pilozzi E,Uggeri G,Torrisi MR,Ferri M,Ziparo V,French D

更新日期：2015-01-07 00:00:00

abstract：:The scientific framework concerning estrogen effects on different tissues has expanded enormously during the last decades, when estrogen receptor (ER) subtypes were identified. Estrogens are not only essential for the female reproductive system, but they also control fundamental functions in other tissues including th...

journal_title：World journal of gastroenterology

authors： Alvaro D,Mancino MG,Onori P,Franchitto A,Alpini G,Francis H,Glaser S,Gaudio E

更新日期：2006-06-14 00:00:00