Ethanol and liver: recent insights into the mechanisms of ethanol-induced fatty liver.

abstract：:Giant duodenal ulcers (GDUs) are a subset of duodenal ulcers that have historically resulted in greater morbidity than usual duodenal ulcers. Until recently, few cases had been successfully treated with medical therapy. However, the widespread use of endoscopy, the introduction of H-2 receptor blockers and proton pump...

journal_title：World journal of gastroenterology

authors： Newton EB,Versland MR,Sepe TE

更新日期：2008-08-28 00:00:00

abstract：:Pancreatic cancer is a leading cause of cancer mortality and the incidence of this disease is expected to continue increasing. While patients with pancreatic cancer have traditionally faced a dismal prognosis, over the past several years various advances in diagnosis and treatment have begun to positively impact this ...

journal_title：World journal of gastroenterology

authors： Mohammed S,Van Buren G 2nd,Fisher WE

更新日期：2014-07-28 00:00:00

abstract：AIM:To assess the clinicopathologic characteristics, risk factors, and prognosis for synchronous multiple early gastric cancer (SMGC). METHODS:A total of 146 patients with SMGC and 1194 patients with single gastric cancer who had undergone gastrectomy between 1989 and 2008 were retrospectively analyzed to determine th...

journal_title：World journal of gastroenterology

authors： Isobe T,Hashimoto K,Kizaki J,Murakami N,Aoyagi K,Koufuji K,Akagi Y,Shirouzu K

更新日期：2013-11-07 00:00:00

abstract：AIM:To investigate the mechanisms of aspirin increasing the susceptibility of Helicobacter pylori (H pylori) to metronidazole. METHODS:H pylori reference strain 26695 and two metronidazole-resistant isolates of H pylori were included in this study. Strains were incubated in Brucella broth with or without aspirin (1 mm...

journal_title：World journal of gastroenterology

authors： Zhang XP,Wang WH,Tian Y,Gao W,Li J

更新日期：2009-02-28 00:00:00

abstract：:Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions are well established biological events which have an important role in not just normal tissue and organ development, but in the pathogenesis of diseases. Increasing evidence has established their presence in the human colon during colorectal carcinoge...

journal_title：World journal of gastroenterology

authors： Sipos F,Galamb O

更新日期：2012-02-21 00:00:00

abstract：:Human intestinal microbiota create a complex polymicrobial ecology. This is characterised by its high population density, wide diversity and complexity of interaction. Any dysbalance of this complex intestinal microbiome, both qualitative and quantitative, might have serious health consequence for a macro-organism, in...

journal_title：World journal of gastroenterology

authors： Bures J,Cyrany J,Kohoutova D,Förstl M,Rejchrt S,Kvetina J,Vorisek V,Kopacova M

更新日期：2010-06-28 00:00:00

abstract：AIM:Eph receptors and ephrin ligands play a pivotal role in development and tissue maintenance. Since previous data have indicated an involvement of ephrin-B2 in epithelial healing, we investigated the gene expression and downstream signaling pathways induced by ephrin-B mediated cell-cell signaling in intestinal epith...

journal_title：World journal of gastroenterology

authors： Hafner C,Meyer S,Hagen I,Becker B,Roesch A,Landthaler M,Vogt T

更新日期：2005-08-07 00:00:00

abstract：:This report describes a case of successful endoscopic management of intragastric penetrated adjustable gastric band in a patient with morbid obesity. The favorable course of the case described here demonstrates that adjustable gastric bands in the process of migration need not be removed surgically in patients who are...

journal_title：World journal of gastroenterology

authors： De Palma GD,Formato A,Pilone V,Rega M,Giuliano ME,Simeoli I,Forestieri P

更新日期：2006-07-07 00:00:00

abstract：:Acute liver failure is a rare and devastating clinical condition. At present, emergency liver transplantation is the only life-saving therapy in advanced cases, yet the feasibility of transplantation is affected by the presence of systemic inflammation, infection and resultant multi-organ failure. The importance of im...

journal_title：World journal of gastroenterology

authors： Donnelly MC,Hayes PC,Simpson KJ

更新日期：2016-07-14 00:00:00

abstract：AIM:To determine the expression of toll-like receptor 9 (TLR9) in pancreatic tumor and the effects of cytosine phosphate-guanosine oligodeoxynucleotides 2216 (CPG ODN2216) on biological behavior of pancreatic carcinoma cell line PANC-1 and explore their clinical significance. METHODS:The immunohistochemistry and Weste...

journal_title：World journal of gastroenterology

authors： Wu HQ,Wang B,Zhu SK,Tian Y,Zhang JH,Wu HS

更新日期：2011-02-28 00:00:00

abstract：AIM:To investigated the effects of urotensin II (UII) on hepatic insulin resistance in HepG2 cells and the potential mechanisms involved. METHODS:Human hepatoma HepG2 cells were cultured with or without exogenous UII for 24 h, in the presence or absence of 100 nmol/L insulin for the last 30 min. Glucose levels were de...

journal_title：World journal of gastroenterology

authors： Li YY,Shi ZM,Yu XY,Feng P,Wang XJ

更新日期：2016-07-07 00:00:00

abstract：:Foreign body ingestion is a common clinical problem in early childhood. However, it may occur even in adults, unknowingly. Most ingested foreign bodies entering the stomach pass through the gastrointestinal tract uneventfully. Here we report on a 13-year-old boy who presented with chronic abdominal pain, weight loss a...

journal_title：World journal of gastroenterology

authors： Müller KE,Arató A,Lakatos PL,Papp M,Veres G

更新日期：2013-06-28 00:00:00

abstract：AIM:To examine the effects of aspirin and enoxaparin on liver function, coagulation index and histopathology in a rat model of liver fibrosis. METHODS Forty-five male Sprague-Dawley rats were randomly divided into the control group (n = 5) and model group (n = 40). Thioacetamide (TAA) was used to induce liver fibrosis ...

journal_title：World journal of gastroenterology

authors： Li CJ,Yang ZH,Shi XL,Liu DL

更新日期：2017-09-21 00:00:00

abstract：AIM:To investigate the protective effect of stronger neo-minophafen C (SNMC) on fulminant hepatic failure (FHF) and its underlying mechanism. METHODS:A mouse model of FHF was established by intraperitoneal injection of galactosamine (D-Gal N) and lipopolysaccharide (LPS). The survival rate, liver function, inflammator...

journal_title：World journal of gastroenterology

authors： Yang BS,Ma YJ,Wang Y,Chen LY,Bi MR,Yan BZ,Bai L,Zhou H,Wang FX

更新日期：2007-01-21 00:00:00

abstract：AIM:To clarify the biological feature contributing to gastric cancer with diffuse bone metastases at diagnosis. METHODS:The participants visited the Department of Clinical Oncology, Akita University Hospital, from January 2014 to August 2015. The selection criterion for gastric cancer with diffuse bone metastases at d...

journal_title：World journal of gastroenterology

authors： Shimazu K,Fukuda K,Yoshida T,Inoue M,Shibata H

更新日期：2016-07-14 00:00:00

abstract：:Patients with inflammatory bowel disease are known to have a high demand of recurrent evaluation for therapy and disease activity. Further, the risk of developing cancer during the disease progression is increasing from year to year. New, mostly non-radiant, quick to perform and quantitative methods are challenging, c...

journal_title：World journal of gastroenterology

authors： Knieling F,Waldner MJ

更新日期：2016-07-07 00:00:00

abstract：:The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), may be complicated by colorectal cancer (CRC). In a recent population-based cohort study of 47 347 Danish patients with IBD by Tine Jess and colleagues 268 patients with UC and 70 patients with CD developed CRC during 30 years of ...

journal_title：World journal of gastroenterology

authors： Andersen V,Halfvarson J,Vogel U

更新日期：2012-08-21 00:00:00

abstract：:P21-activated kinases (PAKs) are central players in various oncogenic signaling pathways. The six PAK family members are classified into group I (PAK1-3) and group II (PAK4-6). Focus is currently shifting from group I PAKs to group II PAKs. Group II PAKs play important roles in many fundamental cellular processes, som...

journal_title：World journal of gastroenterology

authors： Shao YG,Ning K,Li F

更新日期：2016-01-21 00:00:00

abstract：:It has since long been known, from everyday experience as well as from animal and human studies, that psychological processes-both affective and cognitive-exert an influence on gastrointestinal sensorimotor function. More specifically, a link between psychological factors and visceral hypersensitivity has been suggest...

journal_title：World journal of gastroenterology

authors： Van Oudenhove L,Coen SJ,Aziz Q

更新日期：2007-07-07 00:00:00

abstract：AIM:To determine the gene expression profile data for the whole liver during development of dimethylni-trosamine (DMN)-induced hepatic fibrosis. METHODS:Marker genes were identified for different types of hepatic cells, including hepatic stellate cells (HSCs), Kupffer cells (including other inflammatory cells), and he...

journal_title：World journal of gastroenterology

authors： Takahara Y,Takahashi M,Wagatsuma H,Yokoya F,Zhang QW,Yamaguchi M,Aburatani H,Kawada N

更新日期：2006-10-28 00:00:00

abstract：AIM:To investigate DNA ploidy and expression of MMP-9, TIMP-2, and E-cadherin in gastric carcinoma and to explore the mechanism of invasion and metastasis of gastric carcinoma. METHODS:Immunohistochemical methods were used to detect the expressions of MMP-9, TIMP-2, and E-cadherin in 156 cases, including 99 cases of g...

journal_title：World journal of gastroenterology

authors： Zhang JF,Zhang YP,Hao FY,Zhang CX,Li YJ,Ji XR

更新日期：2005-09-28 00:00:00

abstract：:Pancreatic cancer is one of the deadliest cancers, ranking fourth among cancer-related deaths. Despite all the major molecular advances and treatment breakthroughs, mainly targeted therapies, the cornerstone treatment of metastatic pancreatic cancer (mPC) remains cytotoxic chemotherapy. In 2016, more than 40 years aft...

journal_title：World journal of gastroenterology

authors： Ghosn M,Ibrahim T,Assi T,El Rassy E,Kourie HR,Kattan J

更新日期：2016-12-14 00:00:00

abstract：AIM:Single nucleotide polymorphisms (SNPs) of uridine-diphosphoglucuro-nosyltransferase 1A7 (UGT1A7) gene are associated with the development of orolaryngeal cancer, hepatocellular carcinoma, and colorectal cancer. We performed this research to establish the techniques for determining UGT1A7 gene and basic data of this...

journal_title：World journal of gastroenterology

authors： Huang MJ,Yang SS,Lin MS,Huang CS

更新日期：2005-02-14 00:00:00

abstract：AIM:To prospectively investigate the detection rate of laterally spreading tumors (LSTs) of the colorectum by computed tomography (CT) colonography (CTC). METHODS:Patients with LSTs measuring ≥ 20 mm detected during colonoscopy were prospectively enrolled in the study. All patients underwent colonoscopy and subsequent...

journal_title：World journal of gastroenterology

authors： Togashi K,Utano K,Kijima S,Sato Y,Horie H,Sunada K,Lefor AT,Sugimoto H,Yasuda Y

更新日期：2014-12-14 00:00:00

abstract：AIM:To study the inhibitory effect of mononuclear bone marrow cell (BMC) transplantation on carbon tetrachloride (CCl(4)) -induced liver fibrosis in rats. METHODS:Rat liver fibrosis models were induced by CCl(4) and alcohol administration. After 8 wk, twenty rats were randomly allocated into treatment group (n = 10) a...

journal_title：World journal of gastroenterology

authors： Cao BQ,Lin JZ,Zhong YS,Huang SB,Lin N,Tang ZF,Chen R,Xiang P,Xu RY

更新日期：2007-03-28 00:00:00

abstract：AIM:To assess the etiology of chronic liver diseases (CLD) from 1998 to 2014 at the outpatient clinic of Gastroenterology of the main hospital in Northwest of Italy among those dedicated to hepatology. METHODS:A random sample of charts of patients referred to for increased liver enzymes between January 1998 and Decemb...

journal_title：World journal of gastroenterology

authors： Saracco GM,Evangelista A,Fagoonee S,Ciccone G,Bugianesi E,Caviglia GP,Abate ML,Rizzetto M,Pellicano R,Smedile A

更新日期：2016-09-28 00:00:00

abstract：:We report a patient with HBV-related hepatocellular carcinoma (HCC) and refractory ascites who had received a peritoneal-venous shunt (PVS) 1 year before liver transplantation. Urgent surgical intervention following bowel obstruction and failure of immunosuppression therapy. No intestinal obstruction was found during ...

journal_title：World journal of gastroenterology

authors： Lin CH,Yu JC,Chen TW,Chan DC,Chen CJ,Hsieh CB

更新日期：2005-09-14 00:00:00

abstract：AIM:To systematically investigate if cGMP/cGMP-dependent protein kinase G (PKG) signaling pathway may participate in dendroaspis natriuretic peptide (DNP)-induced relaxation of gastric circular smooth muscle. METHODS:The content of cGMP in guinea pig gastric antral smooth muscle tissue and perfusion solution were meas...

journal_title：World journal of gastroenterology

authors： Cai CY,Cai ZX,Gu XY,Shan LJ,Wang YX,Yin XZ,Qi QH,Guo HS

更新日期：2008-09-21 00:00:00

abstract：AIM:To construct tree models for classification of diffuse large B-cell lymphomas (DLBCL) by chromosome copy numbers, to compare them with cDNA microarray classification, and to explore models of multi-gene, multi-step and multi-pathway processes of DLBCL tumorigenesis. METHODS:Maximum-weight branching and distance-ba...

journal_title：World journal of gastroenterology

authors： Jiang HY,Huang ZX,Zhang XF,Desper R,Zhao T

更新日期：2007-03-21 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) encompasses a range of liver histology severity and outcomes in the absence of chronic alcohol use. The mildest form is simple steatosis in which triglycerides accumulate within hepatocytes. A more advanced form of NAFLD, non-alcoholic steatohepatitis, includes inflammation and...

journal_title：World journal of gastroenterology

authors： Pacifico L,Nobili V,Anania C,Verdecchia P,Chiesa C

更新日期：2011-07-14 00:00:00