Dendroaspis natriuretic peptide relaxes gastric antral circular smooth muscle of guinea-pig through the cGMP/cGMP-dependent protein kinase pathway.

abstract：:Chronic groin pain (Inguinodynia) following inguinal hernia repair is a significant, though under-reported problem. Mild pain lasting for a few days is common following mesh inguinal hernia repair. However, moderate to severe pain persisting more than 3 mo after inguinal herniorrhaphy should be considered as pathologi...

journal_title：World journal of gastroenterology

authors： Hakeem A,Shanmugam V

更新日期：2011-04-14 00:00:00

abstract：:Recently, there have been reports from liver biopsies that showed the progression of liver fibrosis in liver transplant patients after the cessation of immunosuppression. Herein, we focused on activated hepatic stellate cells expressing alpha smooth muscle actin (α-SMA) to understand the correlation between immunosupp...

journal_title：World journal of gastroenterology

authors： Hirabaru M,Mochizuki K,Takatsuki M,Soyama A,Kosaka T,Kuroki T,Shimokawa I,Eguchi S

更新日期：2014-06-14 00:00:00

abstract：AIM:To investigate the potential effect of inhibitors of phosphodiesterase-5 (PDE-5) for therapy of portal hypertension in liver cirrhosis. METHODS:In the rat model of thioacetamide-induced liver fibrosis/cirrhosis the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) pathway was investigated. Expression and local...

journal_title：World journal of gastroenterology

authors： Schaffner D,Lazaro A,Deibert P,Hasselblatt P,Stoll P,Fauth L,Baumstark MW,Merfort I,Schmitt-Graeff A,Kreisel W

更新日期：2018-10-14 00:00:00

abstract：AIM:To identify the subset of patients with stage IB gastric cancer with an unfavorable prognosis. METHODS:Overall survival (OS) rates were examined in 103 patients with stage IB (T1N1M0 and T2N0M0) gastric cancer between January 2000 and December 2011. Univariate and multivariate analyses were performed to identify r...

journal_title：World journal of gastroenterology

authors： Aoyama T,Yoshikawa T,Fujikawa H,Hayashi T,Ogata T,Cho H,Yamada T,Hasegawa S,Tsuchida K,Yukawa N,Oshima T,Oba MS,Morita S,Rino Y,Masuda M

更新日期：2014-06-07 00:00:00

abstract：:Gallstone ileus is a rare disease and accounts for 1%-4% of all cases of mechanical intestinal obstruction. It usually occurs in the elderly with a female predominance and may result in a high mortality rate. Its diagnosis is difficult and early diagnosis could reduce the mortality. Surgery remains the mainstay of tre...

journal_title：World journal of gastroenterology

authors： Chou JW,Hsu CH,Liao KF,Lai HC,Cheng KS,Peng CY,Yang MD,Chen YF

更新日期：2007-02-28 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the fifth most common tumor worldwide. Multiple treatment options are available for HCC including curative resection, liver transplantation, radiofrequency ablation, trans-arterial chemoembolization, radioembolization and systemic targeted agent like sorafenib. The treatment of HCC de...

journal_title：World journal of gastroenterology

authors： Raza A,Sood GK

更新日期：2014-04-21 00:00:00

abstract：AIM:To evaluate the clinical outcomes of patients undergoing hepatectomy with hemihepatic vascular occlusion (HHO) compared with total hepatic inflow occlusion (THO). METHODS:Randomized controlled trials (RCTs) comparing hemihepatic vascular occlusion and total hepatic inflow occlusion were included by a systematic li...

journal_title：World journal of gastroenterology

authors： Wang HQ,Yang JY,Yan LN

更新日期：2011-07-14 00:00:00

abstract：AIM:To investigate the clinical value of ultrasonographic diagnosis of biliary atresia (BA), a retrospective analysis of the sonogram of 20 children with BA was undertaken. METHODS:Ultrasonography (US) was performed in 20 neonates and infants with BA, which was confirmed with cholangiography by operation or abdominosc...

journal_title：World journal of gastroenterology

authors： Li SX,Zhang Y,Sun M,Shi B,Xu ZY,Huang Y,Mao ZQ

更新日期：2008-06-14 00:00:00

abstract：AIM:To clarify the benefit of surgical excision for patients with extrahepatic metastases of hepatocellular carcinoma (HCC). METHODS:We retrospectively reviewed the medical records of 140 patients with pathologically proven extrahepatic metastases of HCC and evaluated the outcomes of those who had undergone surgical r...

journal_title：World journal of gastroenterology

authors： Chan KM,Yu MC,Wu TJ,Lee CF,Chen TC,Lee WC,Chen MF

更新日期：2009-11-21 00:00:00

abstract：AIM:To investigate whether enteroviral infection might trigger acute pancreatitis in patients made susceptible due to high alcohol consumption. METHODS:Patients with alcohol-induced acute pancreatitis were analyzed for signs of simultaneous or preceding enteroviral infection. We studied the serum samples of 40 patient...

journal_title：World journal of gastroenterology

authors： Khan J,Nordback I,Seppänen H,Lappalainen-Lehto R,Järvinen S,Oikarinen S,Tauriainen S,Räty S,Hyöty H,Sand J

更新日期：2013-06-28 00:00:00

abstract：:Synchronous occurrence of epithelial neoplasia and gastrointestinal stromal tumor (GIST) in the stomach is uncommon. Only rare cases have been reported in the literature. We present here a 60-year-old female case of synchronous occurrence of gastric high-level intraepithelial neoplasia and GIST with the features of 22...

journal_title：World journal of gastroenterology

authors： Mou YP,Xu XW,Xie K,Zhou W,Zhou YC,Chen K

更新日期：2010-10-21 00:00:00

abstract：AIM:To evaluate prospectively usefulness of fecal lactoferrin (Lf) and fecal hemoglobin (Hb) in the diagnosis of colorectal diseases. METHODS:Fecal Lf and Hb were measured using ELISA in 872 patients before they underwent colorectal endoscopy. RESULTS:Lf was positive in 18 (50%) of 36 patients with colorectal cancer,...

journal_title：World journal of gastroenterology

authors： Hirata I,Hoshimoto M,Saito O,Kayazawa M,Nishikawa T,Murano M,Toshina K,Wang FY,Matsuse R

更新日期：2007-03-14 00:00:00

abstract：:Although antagonists of tumor necrosis factor have resulted in major therapeutic benefits in inflammatory bowel disease, the magnitude and durability of response are variable. Similar to previously available drugs such as 5-aminosalicylates and immunomodulators, the therapeutic effect is not universal leaving many peo...

journal_title：World journal of gastroenterology

authors： Krishnareddy S,Swaminath A

更新日期：2014-02-07 00:00:00

abstract：BACKGROUND:Pit pattern classification using magnifying chromoendoscopy is the established method for diagnosing colorectal lesions. The Japan Narrow-band-imaging (NBI) Expert Team (JNET) classification is a novel NBI magnifying endoscopic classification that focuses on the vessel, and surface patterns. AIM:To determin...

journal_title：World journal of gastroenterology

authors： Zhang Y,Chen HY,Zhou XL,Pan WS,Zhou XX,Pan HH

更新日期：2020-10-28 00:00:00

abstract：AIM:To evaluate the efficacy and safety of HL tablet extracted from magnolia officinalis for treating patients with nonalcoholic fatty liver disease (NAFLD). METHODS:Seventy-four patients with NAFLD diagnosed by ultrasonography were randomly assigned to 3 groups given high dose (400 mg) HL tablet, low dose (133.4 mg) ...

journal_title：World journal of gastroenterology

authors： Jeong JY,Sohn JH,Baek YH,Cho YK,Kim Y,Kim H

更新日期：2017-08-28 00:00:00

abstract：:The use of thiopurines as immunosuppression for the treatment of refractory or chronic active inflammatory bowel disease is established for both Crohn's disease and ulcerative colitis. Nevertheless, many questions remain concerning the optimal treatment regimens of azathioprine, 6-mercaptopurine and thioguanine. We wi...

journal_title：World journal of gastroenterology

authors： Frei P,Biedermann L,Nielsen OH,Rogler G

更新日期：2013-02-21 00:00:00

abstract：AIM:To establish the transgenic mouse line harbouring complete hepatitis B virus (HBV) genome with mutant s gene (adr subtype). METHODS:Transgenic mice were generated by microinjecting HBV genome into fertilized eggs. Integration, expression, replication of HBV gene and histological changes in transgenic mice were est...

journal_title：World journal of gastroenterology

authors： Ge JH,Zhang LZ,Li JX,Liu H,Liu HM,He J,Yao YC,Yang YJ,Yu HY,Hu YP

更新日期：2004-11-01 00:00:00

abstract：AIM:To evaluate the diagnostic value and safety mainly regarding incidents of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for pancreatic cystic lesions (PCLs). METHODS:A total of 150 consecutive patients with suspected PCLs were prospectively enrolled from April 2015 to November 2016. We finally enro...

journal_title：World journal of gastroenterology

authors： Du C,Chai NL,Linghu EQ,Li HK,Sun YF,Xu W,Wang XD,Tang P,Yang J

更新日期：2017-08-14 00:00:00

abstract：:AIM:To evaluate hepatic energy charge levels of the patients with hepatoma after hepatic artery embolization and its relation to postoperative complications.METHODS:Sixty-nine patients with hepatoma were continuously measured for their arterial blood ketone body ratio (AKBR) and compared with their postoperative clini...

journal_title：World journal of gastroenterology

authors： Li L,Yan LN,Chen XL,Lu WS,Xie XD,Wu YT

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Fibrosis is the single most important predictor of significant morbidity and mortality in patients with chronic liver disease. Established non-invasive tests for monitoring fibrosis are lacking, and new biomarkers of liver fibrosis and function are needed. AIM:To depict the process of liver fibrosis and loo...

journal_title：World journal of gastroenterology

authors： Yu J,He JQ,Chen DY,Pan QL,Yang JF,Cao HC,Li LJ

更新日期：2019-02-28 00:00:00

abstract：AIM:To evaluate the effects of combined radiofrequency ablation and transcatheter arterial embolization with iodized oil on ablation time, maximum output, coagulation diameter, and portal angiography in a porcine liver model. METHODS:Radiofrequency ablation (RFA) was applied to in vivo livers of 10 normal pigs using a...

journal_title：World journal of gastroenterology

authors： Nakai M,Sato M,Sahara S,Kawai N,Tanihata H,Kimura M,Terada M

更新日期：2007-05-28 00:00:00

abstract：AIM:To determine the expression levels of gastrointestinal nesfatin-1 in ventromedial hypothalamic nucleus (VMH)-lesioned (obese) and ventrolateral hypothalamic nucleus (VLH)-lesioned (lean) rats that exhibit an imbalance in their energy metabolism and gastric mobility. METHODS:Male Wistar rats were randomly divided i...

journal_title：World journal of gastroenterology

authors： Tian ZB,Deng RJ,Sun GR,Wei LZ,Kong XJ,Ding XL,Jing X,Zhang CP,Ge YL

更新日期：2014-06-14 00:00:00

abstract：:Intense abdominal pain is a prominent feature of chronic pancreatitis and its treatment remains a major clinical challenge. Basic studies of pancreatic nerves and experimental human pain research have provided evidence that pain processing is abnormal in these patients and in many cases resembles that seen in neuropat...

journal_title：World journal of gastroenterology

authors： Olesen SS,Juel J,Graversen C,Kolesnikov Y,Wilder-Smith OH,Drewes AM

更新日期：2013-11-14 00:00:00

abstract：AIM:To explore the inducing effect of human mutant p27 gene on the apoptosis of the human gastric cancer cell line MKN-45 and its associated mechanisms. METHODS:The recombinant adenovirus Ad-p27mt was constructed to infect the human gastric cancer cell line MKN-45. Using flow cytometry, TUNEL assay and DNA fragment an...

journal_title：World journal of gastroenterology

authors： Zhu JS,Wang L,Cheng GQ,Li Q,Zhu ZM,Zhu L

更新日期：2005-12-21 00:00:00

abstract：AIM:To investigate the role of TIP30 in apoptotic signal pathway in hepatoblastoma cells and to provide a basis for TIP30 as a gene therapy candidate in the regression of hepatoblastoma cells. METHODS:Apoptosis of human hepatoblastoma cell lines HepG2 (p53 wild), Hep3B (p53 null) and PLC/RPF/5 (p53 mutant) infected wi...

journal_title：World journal of gastroenterology

authors： Shi M,Zhang X,Wang P,Zhang HW,Zhang BH,Wu MC

更新日期：2005-01-14 00:00:00

abstract：AIM:To investigate the effects of herbal compound 861 (Cpd 861) on cell proliferation in human hepatic stellate cells (LX-2) and human hepatocellular liver carcinoma cells (HepG2), and expression of alpha-smooth muscle actin (alpha-SMA) in LX-2 cells. METHODS:LX-2 and HepG2 cells were incubated with various concentrat...

journal_title：World journal of gastroenterology

authors： Wang L,Wang J,Wang BE,Xiao PG,Qiao YJ,Tan XH

更新日期：2004-10-01 00:00:00

abstract：:Video capsule endoscopy (CE) since its introduction 13 years back, has revolutionized our approach to small intestinal diseases. Obscure gastrointestinal bleed (OGIB) continues to be the most important indication for CE with a high sensitivity, specificity as well as positive and negative predictive values. It is best...

journal_title：World journal of gastroenterology

authors： Goenka MK,Majumder S,Goenka U

更新日期：2014-08-07 00:00:00

abstract：AIM:To investigate the expression of human telomerase reverse transcriptase gene (hTRT) in gastric cancer (GC) and its relevance with cell cycle regulators including P16INK4, cyclin and P53. METHODS:In situ hybridization (ISH) for hTRT mRNA was performed in 53 cases of gastric cancer and adjacent cancerous tissues. Im...

journal_title：World journal of gastroenterology

authors： Shao JC,Wu JF,Wang DB,Qin R,Zhang H

更新日期：2003-03-01 00:00:00

abstract：AIM:To evaluate when Helicobacter pylori (H. pylori) eradication therapy (ET) should be started in patients with peptic ulcer bleeding (PUB). METHODS:Clinical data concerning adults hospitalized with PUB were retrospectively collected and analyzed. Age, sex, type and stage of peptic ulcer, whether endoscopic therapy w...

journal_title：World journal of gastroenterology

authors： Yoon H,Lee DH,Jang ES,Kim J,Shin CM,Park YS,Hwang JH,Kim JW,Jeong SH,Kim N

更新日期：2015-02-28 00:00:00

abstract：AIM:To study the expression levels of E- selectin, integrin beta1 and immunoglobulin superfamily member-intercellular adhesion molecule-1 (ICAM-1) in human gastric carcinoma cells, and to explore the relationship between these three kinds of cell adhesion molecules and gastric carcinoma. METHODS:The serum contents of ...

journal_title：World journal of gastroenterology

authors： Ke JJ,Shao QS,Ling ZQ

更新日期：2006-06-14 00:00:00