Characteristics and prognosis of synchronous multiple early gastric cancer.

Abstract:

AIM:To assess the clinicopathologic characteristics, risk factors, and prognosis for synchronous multiple early gastric cancer (SMGC). METHODS:A total of 146 patients with SMGC and 1194 patients with single gastric cancer who had undergone gastrectomy between 1989 and 2008 were retrospectively analyzed to determine their clinicopathologic characteristics and postoperative survival. Tumors were classified into groups on the basis of location and histology. Smoking habits were evaluated using the Brinkman index. Clinical and pathological factors were compared using either Fisher's exact test or Pearson's χ(2) test. Logistic regression analysis was performed to identify independent risk factors. Survival rate was calculated using the Kaplan-Meier method. RESULTS:SMGCs accounted for 10.9% of gastric cancer cases and occurred predominantly in elderly male patients with a family history of gastric cancer who were both smokers and drinkers. These tumors were typically macroscopically elevated and histologically differentiated. There were no significant differences between SMGC and single gastric cancer patients with respect to tumor location, tumor size, lymph node metastasis, the number of metastatic lymph nodes, venous invasion, or tumor stage (P = 0.052, P = 0.347, P = 0.595, P = 0.805, P = 0.559, and P = 0.408, respectively). Further, there was no significant difference in postoperative survival between the patient groups (P = 0.200). Of the 146 SMGC patients, a single patient had remnant cancer. CONCLUSION:A careful preoperative endoscopy is necessary for patients who are at high risk of SMGC, and minimally invasive treatment may be indicated in some cases.

journal_name

World J Gastroenterol

authors

Isobe T,Hashimoto K,Kizaki J,Murakami N,Aoyagi K,Koufuji K,Akagi Y,Shirouzu K

doi

10.3748/wjg.v19.i41.7154

subject

Has Abstract

pub_date

2013-11-07 00:00:00

pages

7154-9

issue

41

eissn

1007-9327

issn

2219-2840

journal_volume

19

pub_type

杂志文章
  • Risk factors associated with inflammatory bowel disease: A multicenter case-control study in Brazil.

    abstract:BACKGROUND:The etiology of inflammatory bowel disease (IBD) is unknown, but it is believed to be multifactorial. The hygiene hypothesis proposes that better hygiene conditions would lead to less infectious disease during childhood and favor the development of immune-mediated diseases. AIM:To test the hygiene hypothesi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v26.i25.3611

    authors: Salgado VCL,Luiz RR,Boéchat NLF,Leão IS,Schorr BDC,Parente JML,Lima DC,Silveira Júnior ES,Silva GOS,Almeida NP,Vieira A,de Bueno MLQ,Chebli JM,Bertges ÉR,Brugnara LMDC,Junqueira Neto C,Campbell SBG,Discacciati LL,Céza

    更新日期:2020-07-07 00:00:00

  • Nimesulide inhibits proliferation via induction of apoptosis and cell cycle arrest in human gastric adenocarcinoma cell line.

    abstract:AIM:To evaluate the potential role of Nimesulide, a selective COX-2 inhibitor, in proliferation and apoptosis of gastric adenocarcinoma cells SGC7901. METHODS:Cell counts and MTT assay were used to quantify the influence of Nimesulide in the proliferation of SGC7901 cells. Transmission electron microscopy and flow cyt...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i5.915

    authors: Li JY,Wang XZ,Chen FL,Yu JP,Luo HS

    更新日期:2003-05-01 00:00:00

  • Resection of the uncinate process of the pancreas due to a ganglioneuroma.

    abstract::A 33-year-old woman who presented with epigastric discomfort and diarrhea underwent an abdominal ultrasound (US). This investigation and subsequent contrast-enhanced computed tomography, magnetic resonance imaging and endoscopic US with fine needle aspiration (FNA) revealed a 40 mm well-circumscribed mass in the uncin...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.4334

    authors: Poves I,Burdío F,Iglesias M,Martínez-Serrano Mde L,Aguilar G,Grande L

    更新日期:2009-09-14 00:00:00

  • Cyclophosphamide-associated enteritis: A rare association with severe enteritis.

    abstract::Cyclophosphamide is a potent cytotoxic agent used in many clinical settings. The main risks of cyclophosphamide therapy include hematological disorders, infertility, hemorrhagic cystitis and malignancies. Gastrointestinal side effects reported to date are often non-specific and not severe. We present the first case of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i39.8844

    authors: Yang LS,Cameron K,Papaluca T,Basnayake C,Jackett L,McKelvie P,Goodman D,Demediuk B,Bell SJ,Thompson AJ

    更新日期:2016-10-21 00:00:00

  • Complete radiotherapy response in rectal cancer: A review of the evidence.

    abstract::Complete response to chemoradiotherapy for rectal cancer is becoming a common clinical entity. Techniques to diagnose complete response and how to survey these patients without operative intervention are still unclear. We review the most recent evidence. Barriers to firm conclusions regarding this are heterogeneity of...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.v22.i2.467

    authors: Couch DG,Hemingway DM

    更新日期:2016-01-14 00:00:00

  • Assessment of the hepatic microvascular changes in liver cirrhosis by perfusion computed tomography.

    abstract:AIM:To assess the hepatic microvascular parameters in patients with liver cirrhosis by perfusion computed tomography (CT). METHODS:Perfusion CT was performed in 29 patients without liver disease (control subjects) and 39 patients with liver cirrhosis, including 22 patients with compensated cirrhosis and 17 patients wi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.3532

    authors: Chen ML,Zeng QY,Huo JW,Yin XM,Li BP,Liu JX

    更新日期:2009-07-28 00:00:00

  • Parameters of a severe disease course in ulcerative colitis.

    abstract:AIM:To detect high risk patients with a progressive disease course of ulcerative colitis (UC) requiring immunosuppressive therapy (IT). METHODS:A retrospective, multicenter analysis of 262 UC patients from eight German tertiary inflammatory bowel disease centres was performed. Patients were divided into two groups dep...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v20.i35.12574

    authors: Stallmach A,Nickel L,Lehmann T,Bokemeyer B,Bürger M,Hüppe D,Kruis W,Nikolaus S,Preiss JC,Sturm A,Teich N,Schmidt C

    更新日期:2014-09-21 00:00:00

  • Primary hepatic choriocarcinoma in a 49-year-old man: report of a case.

    abstract::We report a case of hepatic choriocarcinoma in a man diagnosed at autopsy after a rapid downhill clinical course. The patient was a 49-year-old man who presented with acute right-sided abdominal pain. There were no masses palpable on physical examination. Radiographic findings showed large multi-nodular tumors mainly ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i48.9485

    authors: Sekine R,Hyodo M,Kojima M,Meguro Y,Suzuki A,Yokoyama T,Lefor AT,Hirota N

    更新日期:2013-12-28 00:00:00

  • Massive upper gastrointestinal hemorrhage due to invasive hepatocellular carcinoma and hepato-gastric fistula.

    abstract::A 36-year-old male Asian immigrant with a history of hepatitis B and hepatitis C related unresectable hepatocellular carcinoma in the left lobe of the liver presented with hematemesis and severe anemia. He was diagnosed with a liver mass that was resected 8 years ago described as a benign tumor in his home country. He...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v19.i42.7472

    authors: Sayana H,Yousef O,Clarkston WK

    更新日期:2013-11-14 00:00:00

  • Peliosis hepatis complicated by portal hypertension following renal transplantation.

    abstract::Peliosis hepatis is a rare benign disease, but in last years the number of identified cases has increased. This disease is known to be sometimes accompanied by hepatocellular carcinoma. In the recent article, Yu et al describe a case of liver peliosis, characterized by an increased proliferative index. Therefore, addi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v26.i34.5220

    authors: Demyashkin G,Zatsepina M

    更新日期:2020-09-14 00:00:00

  • T cell immune response is correlated with fibrosis and inflammatory activity in hepatitis B cirrhotics.

    abstract:AIM:To explore the relationship among interferon-gamma (IFN-gamma) activity, fibrogenesis, T cell immune responses and hepatic inflammatory activity. METHODS:Peripheral blood samples from a total of 43 hepatitis B cirrhotic patients (LC) and 19 healthy controls (NC) were collected to measure their serum levels of IFN-...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i19.3015

    authors: Tang JT,Fang JY,Gu WQ,Li EL

    更新日期:2006-05-21 00:00:00

  • Importance of the surrounding colonic mucosa in distinguishing between hyperplastic and adenomatous polyps during acetic acid chromoendoscopy.

    abstract:AIM:To examine the characteristics of colonic polyps, where it is difficult to distinguish adenomatous polyps from hyperplastic polyps, with the aid of acetic acid chromoendoscopy. METHODS:Acetic acid spray was applied to colonic polyps smaller than 10 mm before complete excision. Endoscopic images were taken before a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.1903

    authors: Kim JH,Lee SY,Kim BK,Choe WH,Kwon SY,Sung IK,Park HS,Jin CJ

    更新日期:2008-03-28 00:00:00

  • Segregation analysis of hepatocellular carcinoma in a moderately high-incidence area of East China.

    abstract:AIM:To explore the mode of inheritance of hepatocellular carcinoma (HCC) in a moderately high-incidence area of East China. METHODS:A pedigree survey was conducted in 210 families (3315 individuals) ascertained through 210 HCC probands in Haimen, Jiangsu Province. Simple segregation analysis was conducted using SEGRAN...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i11.2428

    authors: Cai RL,Meng W,Lu HY,Lin WY,Jiang F,Shen FM

    更新日期:2003-11-01 00:00:00

  • Hepatocellular carcinoma with chronic B-type hepatitis complicated by autoimmune hemolytic anemia: a case report.

    abstract::A 57-year-old man consulted a local hospital because of a persistent slight fever. At the age of 37 years he was diagnosed having B-type hepatitis, but left the liver dysfunction untreated. Twenty years later, he was diagnosed having chronic hepatitis B, hepatocellular carcinoma (HCC) and macrocytic anemia, and referr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i32.4401

    authors: Okada T,Kubota K,Kita J,Kato M,Sawada T

    更新日期:2007-08-28 00:00:00

  • Differences in characteristics of colorectal neoplasm between young and elderly Thais.

    abstract:AIM:To analyze the differences of clinical characteristics of colorectal neoplasm including polyps between the elderly and young Thai patients. METHODS:Colonoscopy database from December 2000 to October 2004 was retrospectively analyzed. There were 1822 eligible patients who underwent colonoscopy (with a mean age of 5...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i47.7684

    authors: Rerknimitr R,Ratanapanich W,Kongkam P,Kullavanijaya P

    更新日期:2006-12-21 00:00:00

  • Seek protein which can interact with hepatitis B virus X protein from human liver cDNA library by yeast two-hybrid system.

    abstract:AIM:To seek the X associated protein (XAP) with the constructed bait vector pAS2-1X from normal human liver cDNA library. METHODS:The X region of the HBV gene was amplied by PCR and cloned into the eukaryotic expression vector pAS2-1. The reconstituted plasmid pAS2-1X was transformed into the yeast cells and the expre...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v8.i1.95

    authors: Wang XZ,Jiang XR,Chen XC,Chen ZX,Li D,Lin JY,Tao QM

    更新日期:2002-02-01 00:00:00

  • Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis.

    abstract:AIM:To investigate whether butyrate or glutamine enemas could diminish inflammation in experimental diversion colitis. METHODS:Wistar specific pathogen-free rats were submitted to a Hartmann's end colostomy and treated with enemas containing glutamine, butyrate, or saline. Enemas were administered twice a week in the ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i32.4278

    authors: Pacheco RG,Esposito CC,Müller LC,Castelo-Branco MT,Quintella LP,Chagas VL,de Souza HS,Schanaider A

    更新日期:2012-08-28 00:00:00

  • Outcomes for jejunal interposition reconstruction compared with Roux-en-Y anastomosis: A meta-analysis.

    abstract:AIM:To compare the clinical outcomes between jejunal interposition reconstruction and Roux-en-Y anastomosis after total gastrostomy in patients with gastric cancer. METHODS:A systematic literature search was conducted by two independent researchers on PubMed, EMBASE, the Cochrane Library, Google Scholar, and other Eng...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审

    doi:10.3748/wjg.v21.i10.3093

    authors: Fan KX,Xu ZF,Wang MR,Li DT,Yang XS,Guo J

    更新日期:2015-03-14 00:00:00

  • Three-dimensional morphometric analysis for hepatectomy of centrally located hepatocellular carcinoma: a pilot study.

    abstract:AIM:To describe a three-dimensional model (3DM) to accurately reconstruct anatomic relationships of centrally located hepatocellular carcinomas (HCCs). METHODS:From March 2013 to July 2014, reconstructions and visual simulations of centrally located HCCs were performed in 39 patients using a 3D subject-based computed ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i15.4607

    authors: Tian F,Wu JX,Rong WQ,Wang LM,Wu F,Yu WB,An SL,Liu FQ,Feng L,Bi C,Liu YH

    更新日期:2015-04-21 00:00:00

  • Contribution of mononuclear bone marrow cells to carbon tetrachloride-induced liver fibrosis in rats.

    abstract:AIM:To study the inhibitory effect of mononuclear bone marrow cell (BMC) transplantation on carbon tetrachloride (CCl(4)) -induced liver fibrosis in rats. METHODS:Rat liver fibrosis models were induced by CCl(4) and alcohol administration. After 8 wk, twenty rats were randomly allocated into treatment group (n = 10) a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i12.1851

    authors: Cao BQ,Lin JZ,Zhong YS,Huang SB,Lin N,Tang ZF,Chen R,Xiang P,Xu RY

    更新日期:2007-03-28 00:00:00

  • Combination of three-gene immunohistochemical panel and magnetic resonance imaging-detected extramural vascular invasion to assess prognosis in non-advanced rectal cancer patients.

    abstract:AIM:To identify a small, clinically applicable immunohistochemistry (IHC) panel that could be combined with magnetic resonance imaging (MRI)-detected extramural vascular invasion (EMVI) for assessment of prognosis concerning the non-advanced rectal cancer patients prior to operation. METHODS:About 329 patients with pa...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i38.8576

    authors: Li XF,Jiang Z,Gao Y,Li CX,Shen BZ

    更新日期:2016-10-14 00:00:00

  • Mitochondrial uncoupling protein 2 expression in colon cancer and its clinical significance.

    abstract:AIM:To detect the expression of mitochondrial uncoupling protein 2 (UCP2) in colon cancer and analyze the relation between UCP2 expression and clinical pathological features of colon cancer. METHODS:Fifteen colon tissue samples and 15 its adjacent tissue samples were obtained from colon cancer patients during surgical...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i45.5773

    authors: Kuai XY,Ji ZY,Zhang HJ

    更新日期:2010-12-07 00:00:00

  • Diagnosis and management of pancreatic neuroendocrine tumor in von Hippel-Lindau disease.

    abstract::The pancreatic manifestations seen in patients with von Hippel-Lindau (VHL) disease are subdivided into 2 categories: pancreatic neuroendocrine tumors (NET), and cystic lesions, including simple cyst and serous cystadenoma. The VHL-associated cystic lesions are generally asymptomatic and do not require any treatment, ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i36.4515

    authors: Tamura K,Nishimori I,Ito T,Yamasaki I,Igarashi H,Shuin T

    更新日期:2010-09-28 00:00:00

  • Organoids of liver diseases: From bench to bedside.

    abstract::Understanding the occurrence, development, and treatment of liver diseases is the main goal of hepatopathology research. Liver diseases are not only diverse but also highly heterogeneous among individuals. At present, research on liver diseases is conducted mainly through cell culture, animal models, pathological spec...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v25.i16.1913

    authors: Wu LJ,Chen ZY,Wang Y,Zhao JG,Xie XZ,Chen G

    更新日期:2019-04-28 00:00:00

  • Contrast enhanced computed tomography and reconstruction of hepatic vascular system for transjugular intrahepatic portal systemic shunt puncture path planning.

    abstract:AIM:To describe a method for the transjugular intrahepatic portal systemic shunt (TIPS) placement performed with the aid of contrast-enhanced computed tomography (CECT) and three-dimensional reconstructed vascular images (3D RVIs), and to assess its safety and effectiveness. METHODS:Four hundred and ninety patients we...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i32.9623

    authors: Qin JP,Tang SH,Jiang MD,He QW,Chen HB,Yao X,Zeng WZ,Gu M

    更新日期:2015-08-28 00:00:00

  • Intralesional steroid is beneficial in benign refractory esophageal strictures: A meta-analysis.

    abstract:AIM:To analyze the effect of intralesional steroid injections in addition to endoscopic dilation of benign refractory esophageal strictures. METHODS:A comprehensive search was performed in three databases from inception to 10 April 2017 to identify trials, comparing the efficacy of endoscopic dilation to dilation comb...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.3748/wjg.v24.i21.2311

    authors: Szapáry L,Tinusz B,Farkas N,Márta K,Szakó L,Meczker Á,Hágendorn R,Bajor J,Vincze Á,Gyöngyi Z,Mikó A,Csupor D,Hegyi P,Erőss B

    更新日期:2018-06-07 00:00:00

  • Surgical treatment for liver cancer.

    abstract::Primary liver cancer is amongst the commonest tumors worldwide, particularly in parts of the developing world, and is increasing in incidence. Over the past three decades, surgical hepatic resection has evolved from a high risk, resource intensive procedure with limited application, to a safe and commonly performed op...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v16.i8.927

    authors: Tsim NC,Frampton AE,Habib NA,Jiao LR

    更新日期:2010-02-28 00:00:00

  • Is endoscopic ultrasound examination necessary in the management of esophageal cancer?

    abstract::Despite substantial efforts at early diagnosis, accurate staging and advanced treatments, esophageal cancer (EC) continues to be an ominous disease worldwide. Risk factors for esophageal carcinomas include obesity, gastroesophageal reflux disease, hard-alcohol use and tobacco smoking. Five-year survival rates have imp...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v23.i5.751

    authors: DaVee T,Ajani JA,Lee JH

    更新日期:2017-02-07 00:00:00

  • Current treatment for colorectal liver metastases.

    abstract::Surgical resection offers the best opportunity for survival in patients with colorectal cancer metastatic to the liver, with five-year survival rates up to 58% in selected cases. However, only a minority are resectable at the time of diagnosis. Continuous research in this field aims at increasing the percentage of pat...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v17.i36.4067

    authors: Misiakos EP,Karidis NP,Kouraklis G

    更新日期:2011-09-28 00:00:00

  • A review of Helicobacter pylori diagnosis, treatment, and methods to detect eradication.

    abstract::Helicobacter pylori (H. pylori) affects nearly half of the world's population and, thus, is one of the most frequent and persistent bacterial infections worldwide. H. pylori is associated with peptic ulcer disease, gastric ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer. Various diagnostic metho...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i6.1438

    authors: Garza-González E,Perez-Perez GI,Maldonado-Garza HJ,Bosques-Padilla FJ

    更新日期:2014-02-14 00:00:00