Importance of the surrounding colonic mucosa in distinguishing between hyperplastic and adenomatous polyps during acetic acid chromoendoscopy.

abstract：:The treatment of chronic hepatitis C (CHC) is still far from optimal, particularly for those subpopulations that do not respond to the standard combination therapy with Interferon-alpha (IFNalpha) plus ribavirin. Although in some cases the use of higher doses or longer treatment periods may be effective, these approac...

journal_title：World journal of gastroenterology

authors： Moreno-Otero R,Trapero-Marugán M,Gómez-Domínguez E,García-Buey L,Moreno-Monteagudo JA

更新日期：2006-05-07 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the fourth cause of cancer related mortality, and its incidence is rapidly increasing. Viral hepatitis, alcohol abuse, and exposure to hepatotoxins are major risk factors, but nonalcoholic fatty liver disease (NAFLD) associated with obesity, insulin resistance, and type 2 diabetes, is...

journal_title：World journal of gastroenterology

authors： Dongiovanni P,Romeo S,Valenti L

更新日期：2014-09-28 00:00:00

abstract：AIM:To evaluate the feasibility of using multiphoton microscopy (MPM) to assess a tumor regression grading (TRG) system. METHODS:Fresh specimens from seven patients with colorectal carcinoma undergoing neoadjuvant radiochemotherapy at the Fujian Medical University Union Hospital were obtained immediately after proctec...

journal_title：World journal of gastroenterology

authors： Li LH,Chen ZF,Wang XF,Zhuo SM,Li HS,Jiang WZ,Guan GX,Chen JX

更新日期：2015-04-14 00:00:00

abstract：:Peritoneal dissemination represents a devastating form of gastric cancer (GC) progression with a dismal prognosis. There is no effective therapy for this condition. The 5-year survival rate of patients with peritoneal dissemination is 2%, even including patients with only microscopic free cancer cells without macrosco...

journal_title：World journal of gastroenterology

authors： Kanda M,Kodera Y

更新日期：2016-08-14 00:00:00

abstract：AIM:To investigate the characteristics of slow electrical waves and the presence of transient receptor potential melastatin-type 7 (TRPM7) in the human gastrointestinal (GI) tract. METHODS:Conventional microelectrode techniques were used to record intracellular electrical responses from human GI smooth muscle tissue. ...

journal_title：World journal of gastroenterology

authors： Kim BJ,Park KJ,Kim HW,Choi S,Jun JY,Chang IY,Jeon JH,So I,Kim SJ

更新日期：2009-12-14 00:00:00

abstract：AIM:To report the outcome of Chinese patents with non-cystic adenocarcinoma in pancreatic body and tail (NCAPBT) after resection and to discuss its surgical strategy. METHODS:Resection of NCAPBT was performed in eight Chinese patients with complete clinical-pathological data in our hospital from January 2000 to May 20...

journal_title：World journal of gastroenterology

authors： Yan HC,Wu YL,Chen LR,Gao SL

更新日期：2006-09-21 00:00:00

abstract：AIM:To analyze the Hepatitis C virus (HCV) genotype distribution and transmission risk factors in a population of unselected patients in Luxembourg. METHODS:Epidemiological information (gender, age and transmission risks) were collected from 802 patients newly diagnosed for hepatitis C and living in Luxembourg, among ...

journal_title：World journal of gastroenterology

authors： Roman F,Hawotte K,Struck D,Ternes AM,Servais JY,Arendt V,Hoffman P,Hemmer R,Staub T,Seguin-Devaux C,Schmit JC

更新日期：2008-02-28 00:00:00

abstract：:Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. At the molecular level, GISTs can be categorized into two groups based on the causative oncogenic mutations. Approximately 85% of GISTs are caused by gain-of-function mutations in the tyrosine kinase receptor ...

journal_title：World journal of gastroenterology

authors： Zhao Y,Feng F,Guo QH,Wang YP,Zhao R

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:Anemia is considered a public health issue and is often caused by iron deficiency. Iron-deficiency anemia (IDA) often originates from blood loss from lesions in the gastrointestinal tract in men and postmenopausal women, and its prevalence among patients with gastrointestinal bleeding has been estimated to b...

journal_title：World journal of gastroenterology

authors： Cotter J,Baldaia C,Ferreira M,Macedo G,Pedroto I

更新日期：2020-12-07 00:00:00

abstract：AIM:To examine an increased risk of esophageal adenocarcinoma is restricted to patients who develop Barrett's esophagus or whether esophagitis per se is a risk factor for adenocarcinoma. METHODS:A population-based cohort of patients with histological evidence of esophagitis without Barrett's esophagus was constructed ...

journal_title：World journal of gastroenterology

authors： Murphy SJ,Anderson LA,Johnston BT,Fitzpatrick DA,Watson PR,Monaghan P,Murray LJ

更新日期：2005-12-14 00:00:00

abstract：AIM:To evaluate the effect of long-term treatment with leukocyte natural α-interferon (ln-α-IFN) plus ribavirin (RBV). METHODS:Forty-six patients with hepatitis C virus (HCV) recurrence received 3 MU three times a week of ln-α-IFN plus RBV for 1 mo; then, patients with good tolerability (n = 30) were switched to daily...

journal_title：World journal of gastroenterology

authors： Tamè M,Buonfiglioli F,Del Gaudio M,Lisotti A,Cecinato P,Colecchia A,Azzaroli F,D'Errico A,Arena R,Calvanese C,Quarneti C,Ballardini G,Pinna AD,Mazzella G

更新日期：2013-08-28 00:00:00

abstract：AIM:To evaluate the clinical usefulness of (18)F-fluorodeoxyglucose positron emission and computed tomography ((18)F-FDG PET/CT) in restaging of esophageal cancer after surgical resection and radiotherapy. METHODS:Between January 2007 and Aug 2008, twenty histopathologically diagnosed esophageal cancer patients underw...

journal_title：World journal of gastroenterology

authors： Sun L,Su XH,Guan YS,Pan WM,Luo ZM,Wei JH,Zhao L,Wu H

更新日期：2009-04-21 00:00:00

abstract：AIM:To study the effects of palmatine, a known inhibitor on delayed rectifier potassium current and L-type calcium current (I(Ca,L)) in guinea pig ventricular myocytes, on the potassium and calcium currents in isolated rat hepatocytes. METHODS:Tight-seal whole-cell patch-clamp techniques were performed to investigate ...

journal_title：World journal of gastroenterology

authors： Wang F,Zhou HY,Cheng L,Zhao G,Zhou J,Fu LY,Yao WX

更新日期：2003-02-01 00:00:00

abstract：:Functional gastrointestinal disorders (FGID) are heterogeneous disorders with a variety of clinical manifestations, primarily defined by signs and symptoms rather than a definite underlying cause. Their pathophysiology remains obscure and, although it is expected to differ according to the specific FGID, disruptions i...

journal_title：World journal of gastroenterology

authors： Koutouratsas T,Kalli T,Karamanolis G,Gazouli M

更新日期：2019-02-07 00:00:00

abstract：AIM:To investigate the expression of cyclooxygenase-2 (COX-2) in gastric cancer and its relation with the liver metastasis and prognosis. METHODS:Expression of COX-2 mRNA and protein was examined in gastric cancer and its paired substantial normal tissue by semi-quantitative reverse transcription-polymerase chain reac...

journal_title：World journal of gastroenterology

authors： Yu JR,Wu YJ,Qin Q,Lu KZ,Yan S,Liu XS,Zheng SS

更新日期：2005-08-21 00:00:00

abstract：AIM:To investigate the ability of hexahydrocurcumin (HHC) to enhance 5-fluorouracil (5-FU) in inhibiting the growth of HT-29 cells by focusing on cyclooxygenase (COX)-2 expression. METHODS:Antiproliferative effects of HHC and 5-FU, alone and in combination, on growth of HT-29 human colon cancer cells were assessed usi...

journal_title：World journal of gastroenterology

authors： Srimuangwong K,Tocharus C,Yoysungnoen Chintana P,Suksamrarn A,Tocharus J

更新日期：2012-05-21 00:00:00

abstract：:Hepatitis B virus (HBV) infection is still the most common cause of hepatocellular carcinoma and liver cirrhosis world wide. Recently, however, there has been quite dramatic improvement in the understanding of HBV associated liver disease and its treatment. It has become clear that high viral replication is a major ri...

journal_title：World journal of gastroenterology

authors： Tillmann HL

更新日期：2007-01-07 00:00:00

abstract：AIM:To investigate the resistance of Helicobacter pylori (H. pylori) to 6 commonly used antibiotics from 2000 to 2009 in Shanghai. METHODS:A total of 293 H. pylori strains were collected from 2000 to 2009 in Shanghai and tested for their susceptibility to metronidazole, clarithromycin, amoxicillin, furazolidone, levof...

journal_title：World journal of gastroenterology

authors： Sun QJ,Liang X,Zheng Q,Gu WQ,Liu WZ,Xiao SD,Lu H

更新日期：2010-10-28 00:00:00

abstract：AIM:To investigate the relationship between the methylation status in the SLIT2 and TGFB2 promoters and colonic inflammation in inflammatory bowel disease patients. METHODS:We evaluated the methylation status of 2 genes (SLIT2 and TGFB2) in 226 biopsies taken from 62 colonoscopies of 38 patients (29 ulcerative colitis...

journal_title：World journal of gastroenterology

authors： Lobatón T,Azuara D,Rodríguez-Moranta F,Loayza C,Sanjuan X,de Oca J,Fernández-Robles A,Guardiola J,Capellá G

更新日期：2014-08-14 00:00:00

abstract：AIM:Complete resection of the bile duct carcinoma is sometimes difficult by subepithelial spread in the duct wall or direct invasion of adjacent blood vessels. Nonresected extrahepatic bile duct carcinoma has a dismal prognosis, with a life expectancy of about 6 mo to 1 year. To improve the treatment results of locally...

journal_title：World journal of gastroenterology

authors： Kamisawa T,Tu Y,Egawa N,Karasawa K,Matsuda T,Tsuruta K,Okamoto A

更新日期：2005-07-21 00:00:00

abstract：:Significant disparities exist between genders for the development and progression of several gastro-intestinal (GI) diseases including cancer. Differences in incidence between men vs women for colon, gastric and hepatocellular cancers suggest a role for steroid sex hormones in regulation of GI carcinogenesis. Involvem...

journal_title：World journal of gastroenterology

authors： Sukocheva OA,Li B,Due SL,Hussey DJ,Watson DI

更新日期：2015-05-28 00:00:00

abstract：:AIM:To investigate the expression of somatostatin mRNA in various differentiated types of gastric carcinoma.METHODS: By using in situ hybridization and immunohistochemical techniques, the expression of somatostatin mRNA and somatostatin immunoreactivity in the normal gastric mucosa, the poorly, moderately and well-dif...

journal_title：World journal of gastroenterology

authors： Zhang QX,Dou YL,Shi XY,Ding Y

更新日期：1998-02-01 00:00:00

abstract：AIM:To determine the mechanical properties of anastomotic colonic tissue in experimental settings and therefore give a measure of wound healing. METHODS:Thirty-six male Wistar rats were used as experimental models of anastomotic tissue integrity. On the 5th post-operative day, the tensile strength was measured by appl...

journal_title：World journal of gastroenterology

authors： Ekmektzoglou KA,Zografos GC,Kourkoulis SK,Dontas IA,Giannopoulos PK,Marinou KA,Poulakou MV,Perrea DN

更新日期：2006-09-21 00:00:00

abstract：AIM:To investigate GATA5, SFRP2, and ITGA4 methylation in plasma DNA as noninvasive biomarkers for colorectal cancer (CRC) or adenomas. METHODS:There were 57 CRC patients, 30 adenomas patients, and 47 control patients enrolled in this study. Methylation-specific polymerase chain reaction was used to determine the prom...

journal_title：World journal of gastroenterology

authors： Zhang X,Song YF,Lu HN,Wang DP,Zhang XS,Huang SL,Sun BL,Huang ZG

更新日期：2015-03-07 00:00:00

abstract：AIM:To find and identify specific nuclear matrix proteins associated with proliferation and differentiation of carcinoma cells, which will be potential markers for cancer diagnosis and targets in cancer therapy. METHODS:Nuclear matrix proteins were selectively extracted from MGc80-3 cells treated with or without hexam...

journal_title：World journal of gastroenterology

authors： Zhao CH,Li QF

更新日期：2005-08-14 00:00:00

abstract：:Retroperitoneal fibrosis is a rare disease characterized by the development of inflammation and fibrosis in the soft tissues of the retroperitoneum and other abdominal organs. Retroperitoneal fibrosis can be of 2 types: idiopathic and secondary. The recently advocated concept and diagnostic criteria of immunoglobulin ...

journal_title：World journal of gastroenterology

authors： Fujimori N,Ito T,Igarashi H,Oono T,Nakamura T,Niina Y,Hijioka M,Lee L,Uchida M,Takayanagi R

更新日期：2013-01-07 00:00:00

abstract：AIM:To compare the efficacy and safety of single daily amikacin vs. cefotaxime in the 5-d treatment of spontaneous bacterial peritonitis (SBP). METHODS:Thirty-seven cirrhotic patients with SBP, 19 in group A and 18 in group B, were studied. Group A received 1 g of cefotaxime every 6 h, and group B received 500 mg of a...

journal_title：World journal of gastroenterology

authors： Chen TA,Lo GH,Lai KH,Lin WJ

更新日期：2005-11-21 00:00:00

abstract：AIM:To evaluate the outcome of chronic hepatitis B (CHB) in children with or without malignancies. METHODS:Twenty four children (15 boys and 9 girls) with malignancies, followed up by the pediatric gastroenterology outpatient clinic for CHB between January 2000 and December 2013, were enrolled in the study (Group 1). ...

journal_title：World journal of gastroenterology

authors： Usta M,Urgancı N,Yıldırmak ZY,Dogan Vural S

更新日期：2015-02-21 00:00:00

abstract：:Ingested fish bone induced intestinal perforations are seldom diagnosed preoperatively due to incomplete patient history taking and difficulties in image evidence identification. Most literature suggests early surgical intervention to prevent sepsis and complications resulting from fish bone migrations. We report the ...

journal_title：World journal of gastroenterology

authors： Kuo CC,Jen TK,Wen CH,Liu CP,Hsiao HS,Liu YC,Chen KH

更新日期：2012-11-07 00:00:00

abstract：:AIM:To infect mice with Helicobacter pylori and detect immune response against two form of H. pylori.METHODS:An isolate of H. pylori obtained from a patient with gastric cancer was used to infect mice. Fifty mice were divided into eight groups. Two groups served as negative control without any inoculation and internal...

journal_title：World journal of gastroenterology

authors： Hua JS,Bow H,Zheng PY,Yeoh GK,Ng CH,Lim GS

更新日期：1998-12-01 00:00:00