Is interferon-beta an alternative treatment for chronic hepatitis C?

abstract：BACKGROUND:Although previous studies have confirmed the feasibility of magnetic compression anastomosis (MCA), there is still a risk of long-term anastomotic stenosis. For traditional MCA devices, a large device is associated with great pressure, and eventually increased leakage. AIM:To develop a novel MCA device to s...

journal_title：World journal of gastroenterology

authors： Chen H,Ma T,Wang Y,Zhu HY,Feng Z,Wu RQ,Lv Y,Dong DH

更新日期：2020-11-14 00:00:00

abstract：:We report a rare case of a 74-year-old man with metachronous gallbladder cancer and bile duct cancer who underwent curative resection twice, with the operations nine years apart. At the age of 65 years, the patient underwent a cholecystectomy and resection of the liver bed for gallbladder cancer. This was a well-diffe...

journal_title：World journal of gastroenterology

authors： Joo HJ,Kim GH,Jeon WJ,Chae HB,Park SM,Youn SJ,Choi JW,Sung R

更新日期：2009-07-21 00:00:00

abstract：AIM:To determine the incidence of Epstein Barr virus associated gastric carcinoma (GC) in Brazil and compare the expressions of apoptosis related proteins and nitric oxide synthases between EBV positive and negative gastric carcinoma. METHODS:In situ hybridization of EBV-encoded small RNA-1 (EBER-1) and PCR was perfor...

journal_title：World journal of gastroenterology

authors： Begnami MD,Montagnini AL,Vettore AL,Nonogaki S,Brait M,Simoes-Sato AY,Seixas AQ,Soares FA

更新日期：2006-08-21 00:00:00

abstract：AIM:To evaluate the long-term efficacy of endoscopic resection (ER) for small (≤ 4.0 cm) gastric gastrointestinal stromal tumors (GISTs) originating from the muscularis propria layer. METHODS:Between June 2005 and February 2015, we retrospectively analyzed 229 consecutive patients with gastric MP-GISTs who underwent E...

journal_title：World journal of gastroenterology

authors： Zhang Y,Mao XL,Zhou XB,Yang H,Zhu LH,Chen G,Ye LP

更新日期：2018-07-21 00:00:00

abstract：:We herein report a case of bronchial bleeding after radical esophagectomy that was treated with lobectomy. A 65-year-old male who underwent subtotal esophagectomy with three-field lymph node dissection for esophageal carcinoma was referred to our hospital because of sudden hemoptysis. After the esophagectomy, bilatera...

journal_title：World journal of gastroenterology

authors： Kitajima T,Momose K,Lee S,Haruta S,Ueno M,Shinohara H,Fujimori S,Fujii T,Takei R,Kohno T,Udagawa H

更新日期：2015-03-21 00:00:00

abstract：:Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease characterized by progressive fibroinflammatory destruction of the intra- and/or extrahepatic biliary ducts. While its features and disease course can be variable, most patients with PSC have concurrent inflammatory bowel disease and will eventual...

journal_title：World journal of gastroenterology

authors： Fung BM,Lindor KD,Tabibian JH

更新日期：2019-02-14 00:00:00

abstract：AIM:To investigate the role of insulin-like growth factor binding protein-7 (IGFBP-7) in the activation and transdifferentiation of hepatic stellate cells (HSC) in vitro. METHODS:Rat HSC-T6 cells were cultured in separate dishes and treated with various concentration of transforming growth factor (TGF)-beta(1), IGFBP-...

journal_title：World journal of gastroenterology

authors： Liu LX,Huang S,Zhang QQ,Liu Y,Zhang DM,Guo XH,Han DW

更新日期：2009-07-14 00:00:00

abstract：:Duodenal duplication cysts are benign rare congenital anomalies reported mainly in the pediatric population, but seldom in adults. Symptoms depend on the type and location and can present as abdominal pain, distension, dysphagia or dyspepsia. They have been reported to be responsible for duodenal obstruction, pancreat...

journal_title：World journal of gastroenterology

authors： Ko SY,Ko SH,Ha S,Kim MS,Shin HM,Baeg MK

更新日期：2013-10-14 00:00:00

abstract：AIM:To investigate the chemopreventive effects of 1alpha, 25-dihydroxyvitamin D(3) in diethylnitrosamine induced, phenobarbital promoted rat hepatocarcinogenesis. METHODS:The rats were randomly divided into 6 different groups (A-F). Groups A, C and E rats received a single intraperitoneal (i.p.) injection of diethylni...

journal_title：World journal of gastroenterology

authors： Banakar MC,Paramasivan SK,Chattopadhyay MB,Datta S,Chakraborty P,Chatterjee M,Kannan K,Thygarajan E

更新日期：2004-05-01 00:00:00

abstract：AIM:To investigate the effect of activation of canonical Wnt signaling pathway on the proliferation and differentiation of hepatic oval cells in vitro. METHODS:WB-F344 cells were treated with recombinant Wnt3a (20, 40, 80, 160, 200 ng/mL) in serum-free medium for 24 h. Cell proliferation was measured by Brdu incorpora...

journal_title：World journal of gastroenterology

authors： Zhang Y,Li XM,Zhang FK,Wang BE

更新日期：2008-11-21 00:00:00

abstract：AIM:To evaluate the efficacy and safety of capsule oxymatrine in the treatment of chronic hepatitis B. METHODS:A randomised double-blind and placebo-controlled multicenter trial was conducted. Injection of oxymatrine was used as positive-control drug. A total of 216 patients with chronic hepatitis B entered the study ...

journal_title：World journal of gastroenterology

authors： Lu LG,Zeng MD,Mao YM,Li JQ,Wan MB,Li CZ,Chen CW,Fu QC,Wang JY,She WM,Cai X,Ye J,Zhou XQ,Wang H,Wu SM,Tang MF,Zhu JS,Chen WX,Zhang HQ

更新日期：2003-11-01 00:00:00

abstract：AIM:To analyze the modulation of gene expression profile associated with inhibition of liver regeneration in hepatitis B X (HBx)-expressing transgenic mice. METHODS:Microarray technology was performed on liver tissue obtained from 4 control (LacZ) and 4 transgenic mice (HBx-LacZ), 48 h after partial hepatectomy. The s...

journal_title：World journal of gastroenterology

authors： Sidorkiewicz M,Jais JP,Tralhao G,Morosan S,Giannini C,Brezillon N,Soussan P,Delpuech O,Kremsdorf D

更新日期：2008-01-28 00:00:00

abstract：AIM:To elucidate high mobility group-box 3 (HMGB3) protein expression in gastric adenocarcinoma, its potential prognostic relevance, and possible mechanism of action. METHODS:Ninety-two patients with gastric adenocarcinomas surgically removed entered the study. HMGB3 expression was determined by immunohistochemistry t...

journal_title：World journal of gastroenterology

authors： Tang HR,Luo XQ,Xu G,Wang Y,Feng ZJ,Xu H,Shi YW,Zhang Q,Wu LG,Xue CQ,Wang CW,Wu CY

更新日期：2012-12-28 00:00:00

abstract：BACKGROUND:Liver resection is an effective treatment for benign and malignant liver tumors. However, a method for preoperative evaluation of hepatic reserve has not yet been established. Previously reported assessments of preoperative hepatic reserve focused only on liver failure in the early postoperative period and d...

journal_title：World journal of gastroenterology

authors： Ishii M,Itano O,Shinoda M,Kitago M,Abe Y,Hibi T,Yagi H,Takeuchi A,Tsujikawa H,Abe T,Kitagawa Y

更新日期：2020-02-21 00:00:00

abstract：AIM:To analyze the literature on the use of Chinese herbal medicines for the treatment of cholecystitis. METHODS:The literature on treatment of cholecystitis with traditional Chinese medicines (TCM) was analyzed based on the principles and methods described by evidence-based medicine (EBM). Eight databases including M...

journal_title：World journal of gastroenterology

authors： Dong ZY,Wang GL,Liu X,Liu J,Zhu DZ,Ling CQ

更新日期：2012-04-14 00:00:00

abstract：AIM:To investigate the clinical utility of biological age (BA) measurement in screening colonoscopy for the detection of colorectal adenomas in the average-risk population. METHODS:A consecutive series of asymptomatic subjects aged ≥ 30 years who underwent colonoscopy in routine check-ups were enrolled. Colorectal ade...

journal_title：World journal of gastroenterology

authors： Kim SJ,Kim BJ,Kang H

更新日期：2017-10-07 00:00:00

abstract：AIM:To evaluate the impact of early steroid withdrawal on the incidence of rejection, tumor recurrence and complications after liver transplantation for advanced-stage hepatocellular carcinoma. METHODS:Fifty-four patients underwent liver transplantation for advanced-stage hepatocellular carcinoma from April 2003 to Ju...

journal_title：World journal of gastroenterology

authors： Chen ZS,He F,Zeng FJ,Jiang JP,Du DF,Liu B

更新日期：2007-10-21 00:00:00

abstract：:A 33-year-old woman who presented with epigastric discomfort and diarrhea underwent an abdominal ultrasound (US). This investigation and subsequent contrast-enhanced computed tomography, magnetic resonance imaging and endoscopic US with fine needle aspiration (FNA) revealed a 40 mm well-circumscribed mass in the uncin...

journal_title：World journal of gastroenterology

authors： Poves I,Burdío F,Iglesias M,Martínez-Serrano Mde L,Aguilar G,Grande L

更新日期：2009-09-14 00:00:00

abstract：AIM:To understand the complex reaction of gastric inflammation induced by Helicobacter pylori (H pylori) in a systematic manner using a protein interaction network. METHODS:The expression of genes significantly changed on microarray during H pylori infection was scanned from the web literary database and translated in...

journal_title：World journal of gastroenterology

authors： Kim KK,Kim HB

更新日期：2009-09-28 00:00:00

abstract：AIM:To explore the transcriptional gene expression profiles of HGF/SF-met signaling pathway in colorectal carcinoma to understand mechanisms of the signaling pathway at so gene level. METHODS:Total RNA was isolated from human colorectal carcinoma cell line LoVo treated with HGF/SF (80 ng/L) for 48 h. Fluorescent probe...

journal_title：World journal of gastroenterology

authors： Li XN,Ding YQ,Liu GB

更新日期：2003-08-01 00:00:00

abstract：AIM:To study the role of hepatic sinusoidal capillarization and perisinusoidal fibrosis in rats with alcohol-induced portal hypertension and to discuss the pathological mechanisms of alcohol-induced hepatic portal hypertension. METHODS:Fifty SD rats were divided into control group (n=20) and model group (n=30). Alcoho...

journal_title：World journal of gastroenterology

authors： Li J,Niu JZ,Wang JF,Li Y,Tao XH

更新日期：2005-11-07 00:00:00

abstract：AIM:To assess the safety of bismuth used in Helicobacter pylori (H pylori) eradication therapy regimens. METHODS:We conducted a systematic review and meta-analysis. MEDLINE and EMBASE were searched (up to October 2007) to identify randomised controlled trials comparing bismuth with placebo or no treatment, or bismuth ...

journal_title：World journal of gastroenterology

authors： Ford AC,Malfertheiner P,Giguere M,Santana J,Khan M,Moayyedi P

更新日期：2008-12-28 00:00:00

abstract：AIM:To evaluate the possible influences of HCV infection and relative antiviral treatment on seminal parameters and reproductive hormonal serum levels. METHODS:Ten male patients with HCV-related chronic hepatitis and 16 healthy male volunteers were studied. In all subjects seminal parameters (nemaspermic concentration...

journal_title：World journal of gastroenterology

authors： Durazzo M,Premoli A,Di Bisceglie C,Bertagna A,Faga E,Biroli G,Manieri C,Bo S,Pagano G

更新日期：2006-05-21 00:00:00

abstract：AIM:To examine the effect of Fusobacterium nucleatum (F. nucleatum) on the microenvironment of colonic neoplasms and the expression of inflammatory mediators and microRNAs (miRNAs). METHODS:Levels of F. nucleatum DNA, cytokine gene mRNA (TLR2, TLR4, NFKB1, TNF, IL1B, IL6 and IL8), and potentially interacting miRNAs (m...

journal_title：World journal of gastroenterology

authors： Proença MA,Biselli JM,Succi M,Severino FE,Berardinelli GN,Caetano A,Reis RM,Hughes DJ,Silva AE

更新日期：2018-12-21 00:00:00

abstract：:Proton pump inhibitors (PPIs) represent a milestone in the treatment of acid-related diseases, and are the mainstay in preventing upper gastrointestinal bleeding in high-risk patients treated with nonsteroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin. However, this beneficial effect does not extend to the ...

journal_title：World journal of gastroenterology

authors： Lué A,Lanas A

更新日期：2016-12-28 00:00:00

abstract：AIM:To assess the value of magnetic resonance elastography (MRE) in detecting advanced fibrosis/cirrhosis in autoimmune hepatitis (AIH). METHODS:In this retrospective study, 36 patients (19 treated and 17 untreated) with histologically confirmed AIH and liver biopsy performed within 3 mo of MRE were identified at a te...

journal_title：World journal of gastroenterology

authors： Wang J,Malik N,Yin M,Smyrk TC,Czaja AJ,Ehman RL,Venkatesh SK

更新日期：2017-02-07 00:00:00

abstract：:Liver transplantation has emerged as a life-saving treatment for several patients with acute liver failure, end stage liver disease and primary hepatic malignancies. However, long term immunosuppressive therapy aiming to reduce the risk of transplant rejection increases the incidence of several complications including...

journal_title：World journal of gastroenterology

authors： Dierickx D,Cardinaels N

更新日期：2015-10-21 00:00:00

abstract：AIM:To investigate the causes of missed diagnosis of early gastric cancer (EGC) or high-grade intraepithelial neoplasia (HGIN) in Chongqing, China. METHODS:The present study summarizes 103 cases of EGC/HGIN detected by esophagogastroduodenoscopy (EGD) and pathological analysis from January 2010 to December 2011. Dimet...

journal_title：World journal of gastroenterology

authors： Ren W,Yu J,Zhang ZM,Song YK,Li YH,Wang L

更新日期：2013-04-07 00:00:00

abstract：:Alcohol consumption and hepatitis C virus (HCV) infection have a synergic hepatotoxic effect, and the coexistence of these factors increases the risk of advanced liver disease. The main mechanisms of this effect are increased viral replication and altered immune response, although genetic predisposition may also play ...

journal_title：World journal of gastroenterology

authors： Novo-Veleiro I,Alvela-Suárez L,Chamorro AJ,González-Sarmiento R,Laso FJ,Marcos M

更新日期：2016-01-28 00:00:00

abstract：:A female patient with anemia and hypoalbuminemia was admitted to our hospital due to an over 20-year history of recurrent dizziness, fatigue and ankle edema. She was diagnosed as multiple chronic non-specific ulcer of the small intestine characterized by non-specific histology and persistent gastrointestinal bleeding....

journal_title：World journal of gastroenterology

authors： Chen Y,Ma WQ,Chen JM,Cai JT

更新日期：2010-02-14 00:00:00