Differential expression of apoptosis related proteins and nitric oxide synthases in Epstein Barr associated gastric carcinomas.

abstract：AIM:To evaluate the efficacy of amantadine plus interferon-alpha and ribavirin in non-responder patients with chronic hepatitis C. METHODS:Twenty-six non-responder patients received the regimen of IFN-alpha-2a at a dose of 6 million units three times a week, 1 000-1 200 mg of ribavirin daily, and 200 mg of amantadine ...

journal_title：World journal of gastroenterology

authors： Oguz D,Cicek B,Filik L,Odemis B,Kilic M,Altintas E,Zengin N,Altiparmak E

更新日期：2005-01-28 00:00:00

abstract：AIM:To elucidate the effect of p27(KIP1) on cell cycle and apoptosis regulation in gastric carcinoma cells. METHODS:The whole length of p27(KIP1) cDNA was transfected into human gastric cancer cell line SCG7901 by lipofectamine. Expression of p27(KIP1) protein or mRNA was analyzed by Western blot and RNA dot blotting,...

journal_title：World journal of gastroenterology

authors： Zheng JY,Wang WZ,Li KZ,Guan WX,Yan W

更新日期：2005-12-07 00:00:00

abstract：:Cancer is currently one of the most important public health problems in the world. Pancreatic cancer is a fatal disease with poor prognosis. As in most other countries, the health burden of pancreatic cancer in China is increasing, with annual mortality rates almost equal to incidence rates. The increasing trend of pa...

journal_title：World journal of gastroenterology

authors： Lin QJ,Yang F,Jin C,Fu DL

更新日期：2015-07-14 00:00:00

abstract：AIM:To evaluate the treatment of pediatric functional chronic intestinal constipation (FCIC) with a probiotic goat yogurt. METHODS:A crossover double-blind formula-controlled trial was carried out on 59 students (age range: 5-15 years) of a public school in Belo Horizonte, MG, Brazil, presenting a FCIC diagnostic, acc...

journal_title：World journal of gastroenterology

authors： Guerra PV,Lima LN,Souza TC,Mazochi V,Penna FJ,Silva AM,Nicoli JR,Guimarães EV

更新日期：2011-09-14 00:00:00

abstract：:E2F family of transcription factors regulates various cellular functions related to cell cycle and apoptosis. Its individual members have traditionally been classified into activators and repressors, based on in vitro studies. However their contribution in human cancer is more complicated and difficult to predict. We ...

journal_title：World journal of gastroenterology

authors： Xanthoulis A,Tiniakos DG

更新日期：2013-06-07 00:00:00

abstract：AIM:To clarify the clinicopathological characteristics of small and large early invasive colorectal cancers (EI-CRCs), and to determine whether malignancy grade depends on size. METHODS:A total of 583 consecutive EI-CRCs treated by endoscopic mucosal resection or surgery at the National Cancer Center Hospital between ...

journal_title：World journal of gastroenterology

authors： Matsuda T,Saito Y,Fujii T,Uraoka T,Nakajima T,Kobayashi N,Emura F,Ono A,Shimoda T,Ikematsu H,Fu KI,Sano Y,Fujimori T

更新日期：2009-06-14 00:00:00

abstract：:Diarrhea after bariatric procedures, mainly those with malabsorptive elements including Roux-Y Gastric Bypass and Biliopancreatic Diversion, is common and an essential determinant of quality of life and micro- and macronutrient deficiencies. Bariatric surgery is the only sustainably successful method to address morbid...

journal_title：World journal of gastroenterology

authors： Borbély YM,Osterwalder A,Kröll D,Nett PC,Inglin RA

更新日期：2017-07-14 00:00:00

abstract：:Eosinophilic oesophagitis (EoE) is a chronic, antigen mediated disease of the disease of the oesophagus that may present in both adults and children. It is characterised by intermittent dysphagia, food bolus obstruction and weight loss. The pathogenesis is incompletely understood but is thought to culminate in poor co...

journal_title：World journal of gastroenterology

authors： Attwood SE,Wilson MS

更新日期：2013-02-14 00:00:00

abstract：AIM:To explore the relationship between α-fetoprotein (AFP) and various clinicopathological variables and different staging system of hepatocellular carcinoma (HCC) thoroughly. METHODS:A retrospective cohort study of consecutive patients diagnosed with HCC between January 2008 and December 2009 in West China Hospital ...

journal_title：World journal of gastroenterology

authors： Liu C,Xiao GQ,Yan LN,Li B,Jiang L,Wen TF,Wang WT,Xu MQ,Yang JY

更新日期：2013-03-21 00:00:00

abstract：AIM:To investigate the prognostic value of vascular endothelial growth factor messenger RNA (VEGF mRNA) in the peripheral blood (PB) of patients with hepatocellular carcinoma (HCC) undergoing curative resection. METHODS:Using a reverse-transcription polymerase chain reaction (RT-PCR)-based assay, VEGF mRNA in the PB w...

journal_title：World journal of gastroenterology

authors： Jeng KS,Sheen IS,Wang YC,Gu SL,Chu CM,Shih SC,Wang PC,Chang WH,Wang HY

更新日期：2004-03-01 00:00:00

abstract：:Cyclophosphamide is a potent cytotoxic agent used in many clinical settings. The main risks of cyclophosphamide therapy include hematological disorders, infertility, hemorrhagic cystitis and malignancies. Gastrointestinal side effects reported to date are often non-specific and not severe. We present the first case of...

journal_title：World journal of gastroenterology

authors： Yang LS,Cameron K,Papaluca T,Basnayake C,Jackett L,McKelvie P,Goodman D,Demediuk B,Bell SJ,Thompson AJ

更新日期：2016-10-21 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease that might affect up to one-third of the adult population in industrialised countries. NAFLD incorporates histologically and clinically different non-alcoholic entities; fatty liver (NAFL, steatosis hepatis) and steatohepatitis (NASH-characterised by...

journal_title：World journal of gastroenterology

authors： Firneisz G

更新日期：2014-07-21 00:00:00

abstract：:Colorectal cancer (CRC) remains one of the major public health problems throughout the world. Originally depicted as a multi-step dynamical disease, CRC develops slowly over several years and progresses through cytologically distinct benign and malignant states, from single crypt lesions through adenoma, to malignant ...

journal_title：World journal of gastroenterology

authors： Grizzi F,Bianchi P,Malesci A,Laghi L

更新日期：2013-01-14 00:00:00

abstract：AIM:To investigate the effects of exogenously mutated p27(kipl) (p27) on proliferation and apoptosis of human cholangiocarcinoma cell line, QBC(939)in vivo. METHODS:Adenviral vectors were used to transfect mutated p27 cDNA into human QBC(939)cell line. Expression of p27 was detected by RT-PCR. Western blot. Cell growt...

journal_title：World journal of gastroenterology

authors： Luo J,Chen YJ,Wang WY,Zou SQ

更新日期：2008-09-14 00:00:00

abstract：AIM:To examine the effect of Fusobacterium nucleatum (F. nucleatum) on the microenvironment of colonic neoplasms and the expression of inflammatory mediators and microRNAs (miRNAs). METHODS:Levels of F. nucleatum DNA, cytokine gene mRNA (TLR2, TLR4, NFKB1, TNF, IL1B, IL6 and IL8), and potentially interacting miRNAs (m...

journal_title：World journal of gastroenterology

authors： Proença MA,Biselli JM,Succi M,Severino FE,Berardinelli GN,Caetano A,Reis RM,Hughes DJ,Silva AE

更新日期：2018-12-21 00:00:00

abstract：BACKGROUND:It is unclear whether immune escape-associated mutations in the major hydrophilic region of hepatitis B virus surface antigen (HBsAg) are associated with nucleoside/nucleotide analog resistance. AIM:To evaluate the association between immune escape-associated mutations and nucleoside/nucleotide analog resis...

journal_title：World journal of gastroenterology

authors： Huang BX,Liu Y,Fan ZP,Si LL,Chen RJ,Wang J,Luo D,Wang FS,Xu DP,Liu XG

更新日期：2020-09-21 00:00:00

abstract：:Patients with long-standing inflammatory bowel disease (IBD) have an increased risk of developing colorectal cancer (CRC). Many of the molecular alterations responsible for sporadic colorectal cancer, namely chromosomal instability, microsatellite instability, and hypermethylation, also play a role in colitis-associat...

journal_title：World journal of gastroenterology

authors： Xie J,Itzkowitz SH

更新日期：2008-01-21 00:00:00

abstract：:An 85 year male patient complaining epigastric discomfort was admitted. From the esophagogastroduodenoscopy, three early gastric cancer (EGCa) lesions had been identified and these were diagnosed as adenocarcinoma with poorly differentiated cell type. The patient underwent operation. From the post-operative mapping, h...

journal_title：World journal of gastroenterology

authors： Seong H,Kim JI,Lee HJ,Kim HJ,Cho HJ,Kim HK,Cheung DY,Kim DJ,Kim W,Kim TJ

更新日期：2013-11-28 00:00:00

abstract：AIM:To assess the outcome of patients, who underwent transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) and subsequently liver transplantation (OLT) irrespective of tumor size when no tumor progression was observed. METHODS:Records, imaging studies and pathology of 84 patients with HCC were revi...

journal_title：World journal of gastroenterology

authors： Obed A,Beham A,Püllmann K,Becker H,Schlitt HJ,Lorf T

更新日期：2007-02-07 00:00:00

abstract：:Penicillium marneffei (P. marneffei) infection usually occurs with skin, bone marrow, lung or hepatic involvement. However, no cases of P. marneffei infection with chylous ascites have been reported thus far. In this report, we describe the first case of acquired immune deficiency syndrome (AIDS) which has been compli...

journal_title：World journal of gastroenterology

authors： Shen YZ,Wang ZY,Lu HZ

更新日期：2012-10-07 00:00:00

abstract：:The advances of laparoscopic surgery since the early 1990s have caused one of the largest technical revolutions in medicine since the detection of antibiotics (1922, Flemming), the discovery of DNA structure (1953, Watson and Crick), and solid organ transplantation (1954, Murray). Perseverance through a rocky start an...

journal_title：World journal of gastroenterology

authors： Kaiser AM

更新日期：2014-11-07 00:00:00

abstract：AIM:To perform a systematic review and meta-analysis for the diagnostic accuracy of in vivo lesion characterization in colonic inflammatory bowel disease (IBD), using optical imaging techniques, including virtual chromoendoscopy (VCE), dye-based chromoendoscopy (DBC), magnification endoscopy and confocal laser endomicr...

journal_title：World journal of gastroenterology

authors： Lord R,Burr NE,Mohammed N,Subramanian V

更新日期：2018-03-14 00:00:00

abstract：:Dysphagia associated with esophageal mechanical obstruction is usually related to malignant esophageal diseases. Benign lesions are rarely a cause for this type of dysphagia, and usually occur either as an intramural tumor or as an extrinsic compression. Mediastinal tuberculous lymphadenitis is rare in adults, and eve...

journal_title：World journal of gastroenterology

authors： Pimenta AP,Preto JR,Gouveia AM,Fonseca E,Pimenta MM

更新日期：2007-12-07 00:00:00

abstract：AIM:To investigate the expression of human telomerase reverse transcriptase gene (hTRT) in gastric cancer (GC) and its relevance with cell cycle regulators including P16INK4, cyclin and P53. METHODS:In situ hybridization (ISH) for hTRT mRNA was performed in 53 cases of gastric cancer and adjacent cancerous tissues. Im...

journal_title：World journal of gastroenterology

authors： Shao JC,Wu JF,Wang DB,Qin R,Zhang H

更新日期：2003-03-01 00:00:00

abstract：AIM:To assess the clinicopathological and biological significance of cripto in human colorectal cancer. METHODS:Real-time reverse-transcription polymerase chain reaction (PCR) was used to examine cripto mRNA levels in primary colon cancer and normal colon tissues as well as normal and metastatic lymph nodes from colon...

journal_title：World journal of gastroenterology

authors： Jiang PC,Zhu L,Fan Y,Zhao HL

更新日期：2013-12-14 00:00:00

abstract：AIM:To study the effect of rosiglitazone, which is a ligand of peroxisome proliferator-activated receptor gamma (PPARgamma), on the expression of PPARgamma in hepatic stellate cells (HSCs) and on the biological characteristics of HSCs. METHODS:The activated HSCs were divided into three groups: control group, 3 micromo...

journal_title：World journal of gastroenterology

authors： Guo YT,Leng XS,Li T,Peng JR,Song SH,Xiong LF,Qin ZZ

更新日期：2005-08-14 00:00:00

abstract：AIM:To elucidate the efficacy and safety of a split dose of midazolam in combination with meperidine for colonoscopy. METHODS:Eighty subjects undergoing outpatient colonoscopy were randomly assigned to group A or B. Group A (n = 40) received a split dose of midazolam in combination with meperidine. Group B (n = 40) re...

journal_title：World journal of gastroenterology

authors： Lee H,Kim JH

更新日期：2009-08-14 00:00:00

abstract：AIM:A circannual variation in the onset of several acute diseases, mostly dealing with cardiovascular system, has been reported. The present study was to verify the possible existence of a seasonal variability in the onset of acute pancreatitis. METHODS:All patients consecutively admitted to the Hospital of Ferrara, I...

journal_title：World journal of gastroenterology

authors： Gallerani M,Boari B,Salmi R,Manfredini R

更新日期：2004-11-15 00:00:00

abstract：AIM:To study the protective effect of Astragalus membranaceus on intestinal mucosa reperfusion injury and its mechanism after hemorrhagic shock in rats. METHODS:A total of 32 SD rats were randomly divided into four groups (n = 8, each group): normal group, model group, low dosage group (treated with 10 g/kg Astragalus...

journal_title：World journal of gastroenterology

authors： Hei ZQ,Huang HQ,Zhang JJ,Chen BX,Li XY

更新日期：2005-08-28 00:00:00

abstract：AIM:To compare ghrelin levels in plasma and gastric mucosa before and after Helicobacter pylori (H. pylori) treatment in children with H. pylori-associated functional dyspepsia. METHODS:Children with H. pylori-associated functional dyspepsia were enrolled in this study. H. pylori infection was confirmed by positive ba...

journal_title：World journal of gastroenterology

authors： Deng ZH,Chu B,Xu YZ,Zhang B,Jiang LR

更新日期：2012-09-28 00:00:00