Size does not determine the grade of malignancy of early invasive colorectal cancer.

abstract：:Tumors of the minor papilla of the duodenum are quite rare. We successfully and safely treated an 18-mm adenoma of the minor papilla associated with pancreas divisum using endoscopic papillectomy. A 64-year-old man was admitted to our hospital for treatment of an asymptomatic mass in the minor papilla detected by uppe...

journal_title：World journal of gastroenterology

authors： Kanamori A,Kumada T,Kiriyama S,Sone Y,Tanikawa M,Hisanaga Y,Toyoda H,Kawashima H,Itoh A,Hirooka Y,Goto H

更新日期：2009-03-07 00:00:00

abstract：AIM:To evaluate the prophylactic efficacy of hepatitis B immunoglobulin (HBIG) in combination with different nucleos(t)ide analogues. METHODS:A total of 5333 hepatitis B surface antigen-positive patients from the China Liver Transplant Registry database were enrolled between January 2000 and December 2009. Low-dose in...

journal_title：World journal of gastroenterology

authors： Shen S,Jiang L,Xiao GQ,Yan LN,Yang JY,Wen TF,Li B,Wang WT,Xu MQ,Wei YG

更新日期：2015-01-14 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the 10 most common cancers worldwide. There is no ideal treatment for HCC yet and many researchers are trying to improve the effects of treatment by changing therapeutic strategies. As the majority of human cancers seem to exhibit either abnormal p53 gene or disrupted p53 gene ...

journal_title：World journal of gastroenterology

authors： Guan YS,La Z,Yang L,He Q,Li P

更新日期：2007-02-21 00:00:00

abstract：:We report a case of hepatic choriocarcinoma in a man diagnosed at autopsy after a rapid downhill clinical course. The patient was a 49-year-old man who presented with acute right-sided abdominal pain. There were no masses palpable on physical examination. Radiographic findings showed large multi-nodular tumors mainly ...

journal_title：World journal of gastroenterology

authors： Sekine R,Hyodo M,Kojima M,Meguro Y,Suzuki A,Yokoyama T,Lefor AT,Hirota N

更新日期：2013-12-28 00:00:00

abstract：AIM:To determine the effect of chemotherapy on wound healing by giving early preoperative 5-fluorouracil (5-FU) to rats with colonic anastomoses. METHODS:Sixty Albino-Wistar male rats (median weight, 235 g) were used in this study. The rats were fed with standard laboratory food and given tap water ad libitum. The ani...

journal_title：World journal of gastroenterology

authors： Ozel L,Ozel MS,Toros AB,Kara M,Ozkan KS,Tellioglu G,Krand O,Koyuturk M,Berber I

更新日期：2009-09-07 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is a chronic progressive cholestatic granulomatous, and destructive inflammatory lesion of small intralobular and septal bile ducts, which is likely to be caused by an autoimmune mechanism with a the presence of serum antimitochondrial antibodies and a potential tendency to progress to ...

journal_title：World journal of gastroenterology

authors： Reshetnyak VI

更新日期：2015-07-07 00:00:00

abstract：:Despite progress in the treatment of advanced and metastatic pancreatic cancer (PC), the outcome of this disease remains dismal for the majority of patients. Given the moderate efficacy of treatment, prognostic factors may help to guide treatment decisions. Several trials identified baseline performance status as an i...

journal_title：World journal of gastroenterology

authors： Boeck S,Hinke A,Wilkowski R,Heinemann V

更新日期：2007-01-14 00:00:00

abstract：:A female patient with anemia and hypoalbuminemia was admitted to our hospital due to an over 20-year history of recurrent dizziness, fatigue and ankle edema. She was diagnosed as multiple chronic non-specific ulcer of the small intestine characterized by non-specific histology and persistent gastrointestinal bleeding....

journal_title：World journal of gastroenterology

authors： Chen Y,Ma WQ,Chen JM,Cai JT

更新日期：2010-02-14 00:00:00

abstract：:Metastatic colorectal cancer (mCRC) continues to be counted as a major health problem. The introduction of newer cytotoxics, irinotecan and oxaliplatin, has achieved a significant improvement in survival rates. Novel targeted therapies (bevacizumab, and cetuximab) in combination with most efficient chemotherapy regime...

journal_title：World journal of gastroenterology

authors： Saridaki Z,Georgoulias V,Souglakos J

更新日期：2010-03-14 00:00:00

abstract：AIM:To investigate the molecular mechanism and functional consequences of heme oxygenase-1 (HO-1) activation by lansoprazole in endothelial cells and macrophages. METHODS:Expression of HO-1 mRNA was analyzed by Northern blotting. Western blotting was used to determine the HO-1 and ferritin protein levels. NADPH-depend...

journal_title：World journal of gastroenterology

authors： Schulz-Geske S,Erdmann K,Wong RJ,Stevenson DK,Schröder H,Grosser N

更新日期：2009-09-21 00:00:00

abstract：:Bacterial infections are a leading cause of morbidity and mortality among solid organ transplant recipients. Over the last two decades, various multidrug-resistant (MDR) pathogens have emerged as relevant causes of infection in this population. Although this fact reflects the spread of MDR pathogens in health care fac...

journal_title：World journal of gastroenterology

authors： Santoro-Lopes G,de Gouvêa EF

更新日期：2014-05-28 00:00:00

abstract：:Endoscopic mucosal resection (EMR) allows the removal of flat or sessile lesions, laterally spreading tumors, and carcinoma of the colon or the rectum limited to the mucosa or the superficial submucosa. Acute appendicitis is the most common abdominal emergency requiring emergency surgery, and it is also a rare complic...

journal_title：World journal of gastroenterology

authors： Nemoto Y,Tokuhisa J,Shimada N,Gomi T,Maetani I

更新日期：2015-07-21 00:00:00

abstract：:Transforming growth factor-beta (TGF-beta), a prototype of multifunctional cytokine, is a key regulator of extracellular matrix (ECM) assembly and remodeling. Specifically, TGF-beta isoforms have the ability to induce the expression of ECM proteins in mesenchymal cells, and to stimulate the production of protease inhi...

journal_title：World journal of gastroenterology

authors： Verrecchia F,Mauviel A

更新日期：2007-06-14 00:00:00

abstract：:Hepatitis C virus (HCV) infection is estimated to affect 130-150 million people globally which corresponds to 2%-3% of the total world population. It remains the leading indication for liver transplant worldwide and has been demonstrated to negatively impact both patient and graft survival following non-hepatic organ ...

journal_title：World journal of gastroenterology

authors： Belga S,Doucette KE

更新日期：2016-01-28 00:00:00

abstract：:The KRAS oncogene is mutated in approximately 35%-45% of colorectal cancers, and KRAS mutational status testing has been highlighted in recent years. The most frequent mutations in this gene, point substitutions in codons 12 and 13, were validated as negative predictors of response to anti-epidermal growth factor rece...

journal_title：World journal of gastroenterology

authors： Tan C,Du X

更新日期：2012-10-07 00:00:00

abstract：AIM:To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs) therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a systematic search of MEDLINE/PubMed and seven other databases through January 1990 to March 2017 for published studies that evaluated the associatio...

journal_title：World journal of gastroenterology

authors： Trifan A,Stanciu C,Girleanu I,Stoica OC,Singeap AM,Maxim R,Chiriac SA,Ciobica A,Boiculese L

更新日期：2017-09-21 00:00:00

abstract：AIM:To evaluate the possible influences of HCV infection and relative antiviral treatment on seminal parameters and reproductive hormonal serum levels. METHODS:Ten male patients with HCV-related chronic hepatitis and 16 healthy male volunteers were studied. In all subjects seminal parameters (nemaspermic concentration...

journal_title：World journal of gastroenterology

authors： Durazzo M,Premoli A,Di Bisceglie C,Bertagna A,Faga E,Biroli G,Manieri C,Bo S,Pagano G

更新日期：2006-05-21 00:00:00

abstract：AIM:Survivin, a recently identified member of the inhibitor of apoptosis protein family, is expressed during development and in various human cancers. However, its expression in normal tissues and clinical relevance in cancers are still debated. In the present study, we analyzed the expression of the survivin gene in h...

journal_title：World journal of gastroenterology

authors： Wang ZN,Xu HM,Jiang L,Zhou X,Lu C,Zhang X

更新日期：2004-11-01 00:00:00

abstract：AIM:To examine whether high-flow nasal oxygen (HFNO) availability influences the use of general anesthesia (GA) in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS) and associated outcomes. METHODS:In this retrospective study, patients were stratified into 3 eras...

journal_title：World journal of gastroenterology

authors： Schumann R,Natov NS,Rocuts-Martinez KA,Finkelman MD,Phan TV,Hegde SR,Knapp RM

更新日期：2016-12-21 00:00:00

abstract：:We report a 31-year-old woman with Crohn's disease complicated by multiple stenoses and internal fistulas clinically misdiagnosed as small bowel endometriosis, due to the patient's perimenstrual symptoms of mechanical subileus for 3 years; at first monthly, but later continuous, and gradually increasing in severity. W...

journal_title：World journal of gastroenterology

authors： Teke Z,Aytekin FO,Atalay AO,Demirkan NC

更新日期：2008-01-07 00:00:00

abstract：AIM:To improve anti-inflammatory activity while reducing drug doses, we developed a nanoformulation carrying dexamethasone and butyrate. METHODS:Dexamethasone cholesteryl butyrate-solid lipid nanoparticles (DxCb-SLN) were obtained with the warm microemulsion method. The anti-inflammatory activity of this novel nanofor...

journal_title：World journal of gastroenterology

authors： Dianzani C,Foglietta F,Ferrara B,Rosa AC,Muntoni E,Gasco P,Della Pepa C,Canaparo R,Serpe L

更新日期：2017-06-21 00:00:00

abstract：AIM:To determine whether oral glutathione (GSH) administration can alleviate the effects of fasting-induced intestinal atrophy in the small intestinal mucosa. METHODS:Rats were divided into eight groups. One group was fed ad libitum, another was fed ad libitum and received oral GSH, and six groups were administrated s...

journal_title：World journal of gastroenterology

authors： Uchida H,Nakajima Y,Ohtake K,Ito J,Morita M,Kamimura A,Kobayashi J

更新日期：2017-09-28 00:00:00

abstract：:Aggressive cytoreduction can prolong survival in patients with unresectable liver metastases (LM) from neuroendocrine neoplasms (NEN), and minimally invasive, liver-directed therapies are gaining increasing interest. Catheter-based treatments are used in disseminated disease, whereas ablation techniques are usually in...

journal_title：World journal of gastroenterology

authors： Sartori S,Bianchi L,Di Vece F,Tombesi P

更新日期：2020-06-21 00:00:00

abstract：AIM:To establish an animal model with human hepatocyte-repopulated liver for the study of liver cancer metastasis. METHODS:Cell transplantation into mouse livers was conducted using alpha-fetoprotein (AFP)-producing human gastric cancer cells (h-GCCs) and h-hepatocytes as donor cells in a transgenic mouse line express...

journal_title：World journal of gastroenterology

authors： Fujiwara S,Fujioka H,Tateno C,Taniguchi K,Ito M,Ohishi H,Utoh R,Ishibashi H,Kanematsu T,Yoshizato K

更新日期：2012-08-07 00:00:00

abstract：AIM:To evaluate attenuating properties of N-acetylcysteine (NAC) on oxidative stress and liver pathology in rats with non-alcoholic steatohepatitis (NASH). METHODS:Male Sprague-Dawley rats were randomly divided into three groups. Group 1 (control, n=8) was free accessed to regular dry rat chow (RC) for 6 wk. Group 2 (...

journal_title：World journal of gastroenterology

authors： Thong-Ngam D,Samuhasaneeto S,Kulaputana O,Klaikeaw N

更新日期：2007-10-14 00:00:00

abstract：:The use of non-steroidal anti-inflammatory drugs (NSAIDs) is widespread worldwide thanks to their analgesic, anti-inflammatory and antipyretic effects. However, even more attention is placed upon the recurrence of digestive system complications in the course of their use. Recent data suggests that the complications of...

journal_title：World journal of gastroenterology

authors： Utzeri E,Usai P

更新日期：2017-06-14 00:00:00

abstract：AIM:To investigate the effect of epigallocatechin gallate (EGCG) on structural changes of gut microbiota in colorectal carcinogenesis. METHODS:An azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced colitis mouse model was established. Forty-two female FVB/N mice were randomly divided into the following three group...

journal_title：World journal of gastroenterology

authors： Wang X,Ye T,Chen WJ,Lv Y,Hao Z,Chen J,Zhao JY,Wang HP,Cai YK

更新日期：2017-12-14 00:00:00

abstract：AIM:To analyze 67 cases of splenic abscess in a medical center of Taiwan during a period of 19 years. METHODS:From January 1986 to December 2004, a total of 67 patients with splenic abscess were enrolled for the retrospective study. The clinical characteristics, underlying diseases, organism spectra, therapeutic metho...

journal_title：World journal of gastroenterology

authors： Chang KC,Chuah SK,Changchien CS,Tsai TL,Lu SN,Chiu YC,Chen YS,Wang CC,Lin JW,Lee CM,Hu TH

更新日期：2006-01-21 00:00:00

abstract：:The prevalence of anemia across studies on patients with inflammatory bowel disease (IBD) is high (30%). Both iron deficiency (ID) and anemia of chronic disease contribute most to the development of anemia in IBD. The prevalence of ID is even higher (45%). Anemia and ID negatively impact the patient's quality of life....

journal_title：World journal of gastroenterology

authors： Muñoz M,Gómez-Ramírez S,García-Erce JA

更新日期：2009-10-07 00:00:00

abstract：:The number of hepatitis C virus (HCV) infection cases is relatively low in children. This low number may be connected with the lack of screening tests and the asymptomatic course of infection. Currently, mother-to-infant transmission is the most common cause of HCV infection amongst children in developed countries. It...

journal_title：World journal of gastroenterology

authors： Pawlowska M,Domagalski K,Pniewska A,Smok B,Halota W,Tretyn A

更新日期：2015-10-14 00:00:00