N-acetylcysteine attenuates oxidative stress and liver pathology in rats with non-alcoholic steatohepatitis.

abstract：:More than 30 years after the discovery of human hepatitis B virus (HBV) this virus remains to be one of the major global health problems. In infected adolescents or adults, 5%-10% will lead to a chronic carrier state, whereas in infected neonates up to 90% develop chronicity. It is estimated that about 370 million peo...

journal_title：World journal of gastroenterology

authors： Glebe D

更新日期：2007-01-07 00:00:00

abstract：AIM:To demonstrate that caudate lobectomy is a valid treatment in cases of hepatocellular carcinoma (HCC) rupture in the caudate lobe based on our experience with the largest case series reported to date. METHODS:A retrospective study of eight patients presenting with spontaneous rupture and hemorrhage of HCC in the c...

journal_title：World journal of gastroenterology

authors： Hong DF,Liu YB,Peng SY,Pang JZ,Wang ZF,Cheng J,Shen GL,Zhang YB

更新日期：2015-07-14 00:00:00

abstract：AIM:To explore risk factors for lymph node metastases in early gastric cancer (EGC) and to confirm the appropriate range of lymph node dissection. METHODS:A total of 202 patients with EGC who underwent curative gastrectomy with lymphadenectomy in the Department of Surgery, Xinhua Hospital and Ruijin Hospital of Shangh...

journal_title：World journal of gastroenterology

authors： Ren G,Cai R,Zhang WJ,Ou JM,Jin YN,Li WH

更新日期：2013-05-28 00:00:00

abstract：:We describe herein a 68-year-old woman who was diagnosed with a quite rare entity of intraductal papillary mucinous neoplasms (IPMNs) occurring simultaneously in the left lateral lobe of liver and the tail of pancreas. Abdominal computed tomography and magnetic resonance cholangiopancreatography showed a cystic dilata...

journal_title：World journal of gastroenterology

authors： Xu XW,Li RH,Zhou W,Wang J,Zhang RC,Chen K,Mou YP

更新日期：2012-11-28 00:00:00

abstract：:In this paper, we summarize the main progresses made in our group in the field of the mechanism of pigment gallstone formation. It was found that after treatment with free radicals, bilirubin (BR) was changed into free radical itself, and a semiquinone free radical and a superoxide free radical bound with metal were r...

journal_title：World journal of gastroenterology

authors： Liu XT,Hu J

更新日期：2002-06-01 00:00:00

abstract：AIM:To examine the possible effects of honey supplementation on hepatic damage due to obstruction of the common bile duct in an experimental rat model. METHODS:The study was performed with 30 male rats divided into three groups: a sham group, an obstructive jaundice group, and an obstructive jaundice plus honey group....

journal_title：World journal of gastroenterology

authors： Erguder BI,Kilicoglu SS,Namuslu M,Kilicoglu B,Devrim E,Kismet K,Durak I

更新日期：2008-06-21 00:00:00

abstract：:During the last decades, further knowledge of hepatocellular carcinoma (HCC) molecular mechanisms has led to development of effective systemic treatments including tyrosine kinase inhibitors (TKIs) and immunotherapy. In this review, we describe first and second line systemic treatment options for advanced HCC. Several...

journal_title：World journal of gastroenterology

authors： Piñero F,Silva M,Iavarone M

更新日期：2020-04-28 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is the second most common cause of cancer death worldwide. It is broadly described that cyclooxygenase-2 (COX-2) is mainly overexpressed in CRC but less is known regarding post-translational modifications of this enzyme that may regulate its activity, intracellular localization and st...

journal_title：World journal of gastroenterology

authors： Prieto P,Jaén RI,Calle D,Gómez-Serrano M,Núñez E,Fernández-Velasco M,Martín-Sanz P,Alonso S,Vázquez J,Cerdán S,Peinado MÁ,Boscá L

更新日期：2019-01-28 00:00:00

abstract：AIM:To determine whether the expression profiles of EphB receptor and ephrin-B ligand can be used as markers for dysplastic/oncogenic transformation in gastric mucosa. METHODS:The protein expression and localization of EphB and ephrin-B in normal, ulcerated regenerating, and dysplastic gastric mucosa were examined in ...

journal_title：World journal of gastroenterology

authors： Uchiyama S,Saeki N,Ogawa K

更新日期：2015-01-14 00:00:00

abstract：AIM:To analyze RASSF6 expression in pancreatic ductal adenocarcinoma (PDAC) and to determine whether RASSF6 has an independent prognostic value in PDAC. METHODS:We studied RASSF6 expression in 96 histologically confirmed PDAC samples and 20 chronic pancreatitis specimens using immunohistochemistry and real-time quanti...

journal_title：World journal of gastroenterology

authors： Ye HL,Li DD,Lin Q,Zhou Y,Zhou QB,Zeng B,Fu ZQ,Gao WC,Liu YM,Chen RW,Li ZH,Chen RF

更新日期：2015-06-07 00:00:00

abstract：:Laparoscopic gastrectomy has been widely accepted as a standard alternative for the treatment of early-stage gastric adenocarcinoma because of its favorable short-term outcomes. Although controversies exist, such as establishing clear indications, proper preoperative staging, and oncologic safety, experienced surgeons...

journal_title：World journal of gastroenterology

authors： Son T,Hyung WJ

更新日期：2016-01-14 00:00:00

abstract：AIM:To analyze the effects of NF- kappa B inhibition by antioxidant pyrrolidine dithiocarbamate (PDTC) or TNF inhibitor pentoxifylline (PTX) on liver regeneration after partial hepatectomy (PH). METHODS:Saline, PDTC or PTX were injected 1 h before PH and rats were killed at 0.5 and 24 h after PH. Several control group...

journal_title：World journal of gastroenterology

authors： Laurent S,Horsmans Y,Stärkel P,Leclercq I,Sempoux C,Lambotte L

更新日期：2005-12-14 00:00:00

abstract：AIM:To assess the effectiveness of pancreatic stents for preventing pancreatitis in high-risk patients after endoscopic retrograde cholangiopancreatography (ERCP). METHODS:PubMed, Embase, Science Citation Index, and Cochrane Controlled Trials Register were searched to identify relevant trials published in English. Inc...

journal_title：World journal of gastroenterology

authors： Shi QQ,Ning XY,Zhan LL,Tang GD,Lv XP

更新日期：2014-06-14 00:00:00

abstract：:Unidimensional transient elastography (TE) is a noninvasive technique, which has been increasingly used in the assessment of diffuse liver diseases. This paper focuses on reviewing the existing data on the use of TE in the diagnosis of fibrosis and in monitoring disease progression in alcoholic liver disease, on the f...

journal_title：World journal of gastroenterology

authors： Lupsor-Platon M,Badea R

更新日期：2015-11-14 00:00:00

abstract：:We report a case of a 32-year-old woman with episodic right lower quadrant abdominal pain. With the diagnosis of either acute appendicitis or tubo-ovarian abscess, she was treated with antibiotics, which successfully relieved the pain and the inflammatory findings. She repeated the clinical condition a few times and a...

journal_title：World journal of gastroenterology

authors： Niwa H,Hiramatsu T

更新日期：2008-02-28 00:00:00

abstract：:In order to have an adequate view of the whole small intestine during capsule endoscopy, the preparation recommended consists of a clear liquid diet and an overnight fast. However, visualization of the small bowel during video capsule endoscopy can be impaired by intestinal contents. To improve mucosal visualization, ...

journal_title：World journal of gastroenterology

authors： Pons Beltrán V,Carretero C,Gonzalez-Suárez B,Fernandez-Urien I,Muñoz-Navas M

更新日期：2008-10-07 00:00:00

abstract：AIM:To study and provide data on the evolution of medical procedures and outcomes of patients suffering from perforated midgut diverticulitis. METHODS:Three data sources were used: the Medline and Google search engines were searched for case reports on one or more patients treated for perforated midgut diverticulitis ...

journal_title：World journal of gastroenterology

authors： Spasojevic M,Naesgaard JM,Ignjatovic D

更新日期：2012-09-14 00:00:00

abstract：:Colorectal cancer hepatic metastases represent the final stage of a multi-step biological process. This process starts with a series of mutations in colonic epithelial cells, continues with their detachment from the large intestine, dissemination through the blood and/or lymphatic circulation, attachment to the hepati...

journal_title：World journal of gastroenterology

authors： Paschos KA,Majeed AW,Bird NC

更新日期：2014-04-14 00:00:00

abstract：AIM:To observe the therapeutic effects of dexamethasone on rats with severe acute pancreatitis (SAP) and investigate the influences of dexamethasone on the inflammatory mediators and NF-kappaB expression in multiple organs of SAP rats as well as the mechanisms involved. METHODS:Ninety Sprague-Dawley (SD) rats with SAP...

journal_title：World journal of gastroenterology

authors： Zhang XP,Zhang L,Chen LJ,Cheng QH,Wang JM,Cai W,Shen HP,Cai J

更新日期：2007-01-28 00:00:00

abstract：:The efficacy of triple therapy for Helicobacter pylori infection has dramatically declined over the last decade, largely related to increasing clarithromycin resistance rates. From a microbiological standpoint, bismuth quadruple therapy is the ideal replacement since it combines drugs for which resistance does not imp...

journal_title：World journal of gastroenterology

authors： Molina-Infante J,Gisbert JP

更新日期：2014-08-14 00:00:00

abstract：AIM:Oxygen free radical mediated tissue damage is well established in pathogenesis of acute pancreatitis (AP). Whether nitric oxide (NO) plays a deleterious or a protective role is unknown. In alcohol-induced AP, we studied NO, lipooxidative damage and glutathione in pancreas, lung and circulation. METHODS:AP was indu...

journal_title：World journal of gastroenterology

authors： Andican G,Gelisgen R,Unal E,Tortum OB,Dervisoglu S,Karahasanoglu T,Burçak G

更新日期：2005-04-21 00:00:00

abstract：AIM:To study the inhibitory effects of a Shuangling Fuzheng anticancer preparation (SFAP) on the human gastric cancer cell line SGC-7901 in vitro as well as its immune-modulated effects in a cyclophosphamide-treated murine model. METHODS:MTT experiments and immunocytochemistry ABC experiments were performed for detect...

journal_title：World journal of gastroenterology

authors： Chen HS,Chen J,Cui DL,Zheng YY,Xu AH,Chen G,Jia LC

更新日期：2007-12-28 00:00:00

abstract：AIM:To assess the incidence and analyze the risk factors for Clostridium difficile-associated diarrhea (CDAD) after living donor liver transplantation (LDLT) in adult. METHODS:The microbiological data and medical records of 242 adult recipients that underwent LDLT at the Tokyo University Hospital were analyzed retrosp...

journal_title：World journal of gastroenterology

authors： Hashimoto M,Sugawara Y,Tamura S,Kaneko J,Matsui Y,Togashi J,Makuuch M

更新日期：2007-04-14 00:00:00

abstract：AIM:To assess the use of topical negative pressure (TNP) in the management of severe peritonitis. METHODS:This is a four-year prospective analysis from January 2005 to December 2008 of 20 patients requiring TNP following laparotomy for severe peritonitis. RESULTS:There were 11 males with an average age of (59.3 +/- 3...

journal_title：World journal of gastroenterology

authors： Amin AI,Shaikh IA

更新日期：2009-07-21 00:00:00

abstract：AIM:To investigate the biological effects of internal irradiation, and the therapeutic effectiveness was assessed of (131)I-labeled anti-epidermal growth factor receptor (EGFR) liposomes, derived from cetuximab, when used as a tumor-targeting carrier in a colorectal cancer mouse model. METHODS:We described the liposom...

journal_title：World journal of gastroenterology

authors： Li W,Ji YH,Li CX,Liu ZY,Li N,Fang L,Chang J,Tan J

更新日期：2016-04-14 00:00:00

abstract：AIM:To explore the cooperative effects of antisense oligonucleotide (ASON) of cell adhesion molecules and cimetidine on the expression of E-selectin and ICAM-1 in endothelial cells and their adhesion to tumor cells. METHODS:After treatment of endothelial cells with ASON and/or cimetidine and induction with TNF-alpha, ...

journal_title：World journal of gastroenterology

authors： Tang NH,Chen YL,Wang XQ,Li XJ,Yin FZ,Wang XZ

更新日期：2004-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection induces steatosis and is accompanied by multiple metabolic alterations including hyperuricemia, reversible hypocholesterolemia and insulin resistance. Total cholesterol, low-density lipoprotein-cholesterol and triglyceride levels are increased by peginterferon and ribavirin combinatio...

journal_title：World journal of gastroenterology

authors： Kanda T,Moriyama M

更新日期：2017-08-21 00:00:00

abstract：:Bowel preparation is a core issue in colonoscopy, as it is closely related to the quality of the procedure. Patients often find that bowel preparation is the most unpleasant part of the examination. It is widely accepted that the quality of cleansing must be excellent to facilitate detecting neoplastic lesions. In spi...

journal_title：World journal of gastroenterology

authors： Parra-Blanco A,Ruiz A,Alvarez-Lobos M,Amorós A,Gana JC,Ibáñez P,Ono A,Fujii T

更新日期：2014-12-21 00:00:00

abstract：:The management of intraductal papillary mucinous neoplasms (IPMN) is presently evolving as a result of the improved understanding of the natural history and biological behavior of the different pancreatic cystic neoplasms; and better preoperative diagnosis of these neoplasms due to advancement in preoperative diagnost...

journal_title：World journal of gastroenterology

authors： Goh BK

更新日期：2015-09-14 00:00:00

abstract：:A variety of inflammatory diseases of the colon, which can be differentiated from inflammatory bowel disease (IBD) and infectious colitis by their clinical, endoscopic and histological characteristics, are reported as non-IBD and non-infectious colitis. These diseases include microscopic colitis, ischemic colitis, seg...

journal_title：World journal of gastroenterology

authors： Koutroubakis IE

更新日期：2008-12-28 00:00:00