Natural history of hepatic metastases from colorectal cancer--pathobiological pathways with clinical significance.

abstract：AIM:To demonstrate that caudate lobectomy is a valid treatment in cases of hepatocellular carcinoma (HCC) rupture in the caudate lobe based on our experience with the largest case series reported to date. METHODS:A retrospective study of eight patients presenting with spontaneous rupture and hemorrhage of HCC in the c...

journal_title：World journal of gastroenterology

authors： Hong DF,Liu YB,Peng SY,Pang JZ,Wang ZF,Cheng J,Shen GL,Zhang YB

更新日期：2015-07-14 00:00:00

abstract：AIM:To evaluate the feasibility of using multiphoton microscopy (MPM) to assess a tumor regression grading (TRG) system. METHODS:Fresh specimens from seven patients with colorectal carcinoma undergoing neoadjuvant radiochemotherapy at the Fujian Medical University Union Hospital were obtained immediately after proctec...

journal_title：World journal of gastroenterology

authors： Li LH,Chen ZF,Wang XF,Zhuo SM,Li HS,Jiang WZ,Guan GX,Chen JX

更新日期：2015-04-14 00:00:00

abstract：AIM:To investigate the effects of extended lymphadenectomy and postoperative chemotherapy on gastric cancer without lymph node metastasis. METHODS:Clinical data of 311 node-negative gastric cancer patients who underwent potentially curative gastrectomy with more than 15 lymph nodes resected, from January 2002 to Decem...

journal_title：World journal of gastroenterology

authors： Xue Q,Wang XN,Deng JY,Zhang RP,Liang H

更新日期：2013-09-07 00:00:00

abstract：AIM:To explore the preliminary identification of serum protein pattern models that may be novel potential biomarkers in the detection of gastric cancer. METHODS:A total of 130 serum samples, including 70 from patients with gastric cancer and 60 from healthy adults, were detected by surface-enhanced laser desorption an...

journal_title：World journal of gastroenterology

authors： Qian HG,Shen J,Ma H,Ma HC,Su YH,Hao CY,Xing BC,Huang XF,Shou CC

更新日期：2005-10-28 00:00:00

abstract：AIM:To investigate the correlation between the serum soluble intercellular adhesion molecule-1 (sICAM-1) and the clinicopathologic features and to evaluate the possible prognostic significance of sICAM-1 concentration in colorectal cancer. METHODS:A total of 56 patients (mean age 57.3 years) having transitional cell c...

journal_title：World journal of gastroenterology

authors： Kang X,Wang F,Xie JD,Cao J,Xian PZ

更新日期：2005-07-21 00:00:00

abstract：:Elastography-based liver stiffness measurement (LSM) is a non-invasive tool for estimating liver fibrosis but also provides an estimate for the severity of portal hypertension in patients with advanced chronic liver disease (ACLD). The presence of varices and especially of varices needing treatment (VNT) indicates dis...

journal_title：World journal of gastroenterology

authors： Paternostro R,Reiberger T,Bucsics T

更新日期：2019-01-21 00:00:00

abstract：AIM:To investigate the effects of exogenous melatonin on bacterial translocation and apoptosis in a rat ulcerative colitis model. METHODS:Rats were randomly assigned to three groups: group I: control, group II: experimental colitis, group III: colitis plus melatonin treatment. On d 11 after colitis, plasma tumor necro...

journal_title：World journal of gastroenterology

authors： Akcan A,Kucuk C,Sozuer E,Esel D,Akyildiz H,Akgun H,Muhtaroglu S,Aritas Y

更新日期：2008-02-14 00:00:00

abstract：AIM:To establish the prognosis and feasibility of en-bloc vascular resection of stage II pancreatic adenocarcinoma of the head and uncinate process. METHODS:We retrospectively analyzed 87 patients with stage II pancreatic adenocarcinoma, who were subjected to pancreaticoduodenectomy (PD) and pylorus-preserving PD (PPP...

journal_title：World journal of gastroenterology

authors： Chakravarty KD,Hsu JT,Liu KH,Yeh CN,Yeh TS,Hwang TL,Jan YY,Chen MF

更新日期：2010-02-28 00:00:00

abstract：AIM:To investigate the gastric emptying after bowel preparation to allow general anaesthesia. METHODS:A prospective, non-comparative, and non-randomized trial was performed and registered on Eudra CT database (2011-002953-80) and on www.trial.gov (NCT01398098). All patients had a validated indication for colonoscopy a...

journal_title：World journal of gastroenterology

authors： Coriat R,Polin V,Oudjit A,Henri F,Dhooge M,Leblanc S,Delchambre C,Esch A,Tabouret T,Barret M,Prat F,Chaussade S

更新日期：2014-10-07 00:00:00

abstract：AIM:To analyze the predictive factors for lymph node metastasis (LNM) in early gastric cancer (EGC). METHODS:Data from patients surgically treated for gastric cancers between January 1994 and December 2007 were retrospectively collected. Clinicopathological factors were analyzed to identify predictive factors for LNM....

journal_title：World journal of gastroenterology

authors： Sung CM,Hsu CM,Hsu JT,Yeh TS,Lin CJ,Chen TC,Su MY,Chiu CT

更新日期：2010-11-07 00:00:00

abstract：AIM:To investigate the anti-tumor mechanism of antisense oligodeoxynucleotide cantide against hTERT. METHODS:Tumor cells were cultured overnight and grown to 50-60 % confluence. HepG2 and SMMC-7721 were treated with cantide mixed with lipofectin, or lipofectin alone. After inducted for 6 h at 37 degrees, 10 % FCS in D...

journal_title：World journal of gastroenterology

authors： Du QY,Wang XB,Chen XJ,Zheng W,Wang SQ

更新日期：2003-09-01 00:00:00

abstract：:We report a case of intraductal papillary neoplasm of the bile duct (IPNB) that developed in a patient with primary sclerosing cholangitis. A 46-year-old woman was admitted to our hospital with obstructive jaundice. The liver function tests demonstrated increased serum liver enzyme levels. Computed tomography showed d...

journal_title：World journal of gastroenterology

authors： Hachiya H,Kita J,Shiraki T,Iso Y,Shimoda M,Kubota K

更新日期：2014-11-14 00:00:00

abstract：AIM:To compare the performance of the Da-an real-time hepatitis B virus (HBV) DNA assay and Abbott RealTime HBV assay. METHODS:HBV DNA standards as well as a total of 180 clinical serum samples from patients with chronic hepatitis B were measured using the Abbott and Da-an real-time polymerase chain reaction (PCR) ass...

journal_title：World journal of gastroenterology

authors： Qiu N,Li R,Yu JG,Yang W,Zhang W,An Y,Li T,Liu XE,Zhuang H

更新日期：2014-09-07 00:00:00

abstract：AIM:To elucidate the relationship between apoptotic protease activating factor-1 (Apaf-1) gene and gastric cancer. METHODS:Thirty-five postoperative cancer and adjacent normal tissue samples were collected in the present study. Expression of the Apaf-1 gene in these samples was analyzed by semi-quantitative RT-PCR. Lo...

journal_title：World journal of gastroenterology

authors： Wang HL,Bai H,Li Y,Sun J,Wang XQ

更新日期：2007-10-14 00:00:00

abstract：AIM:To investigate whether the apoptotic activities of 8-bromo-7-methoxychrysin (BrMC) involve reactive oxygen species (ROS) generation and c-Jun N-terminal kinase (JNK) activation in human hepatocellular carcinoma cells (HCC). METHODS:HepG2, Bel-7402 and L-02 cell lines were cultured in vitro and the apoptotic effect...

journal_title：World journal of gastroenterology

authors： Yang XH,Zheng X,Cao JG,Xiang HL,Liu F,Lv Y

更新日期：2010-07-21 00:00:00

abstract：AIM:To investigate the expression of leukemia related protein 16 (LRP16), and the possible relationship between LRP16 expression and clinicopathological indices in 336 gastric carcinoma patients. METHODS:Immunohistochemistry was used to detect LRP16 expression in 336 cases of paraffin-embedded gastric carcinoma tissue...

journal_title：World journal of gastroenterology

authors： Li YZ,Zhao P,Han WD

更新日期：2009-10-14 00:00:00

abstract：AIM:To test the Genval recommendations and the usefulness of a short trial of proton pump inhibitor (PPI) in the initial management and maintenance treatment of gastroesophageal reflux disease (GERD) patients. METHODS:Five hundred and seventy seven patients with heartburn were recruited. After completing a psychometri...

journal_title：World journal of gastroenterology

authors： Pace F,Riegler G,de Leone A,Dominici P,Grossi E,EMERGE Study Group.

更新日期：2011-03-07 00:00:00

abstract：AIM:To assess the efficacy and safety of a new treatment modality, cellular immune therapy based on personalized peptide vaccination (PPV-DC-CTL) combined with radiotherapy, for treating advanced hepatocellular carcinoma (HCC). METHODS:A total of nine patients with advanced HCC were enrolled. Multidisciplinary consult...

journal_title：World journal of gastroenterology

authors： Shen J,Wang LF,Zou ZY,Kong WW,Yan J,Meng FY,Chen FJ,Du J,Shao J,Xu QP,Ren HZ,Li RT,Wei J,Qian XP,Liu BR

更新日期：2017-08-07 00:00:00

abstract：AIM:To evaluate the rate of adverse events (AEs) during consecutive gastric and duodenal polypectomies in several Spanish centers. METHODS:Polypectomies of protruded gastric or duodenal polyps ≥ 5 mm using hot snare were prospectively included. Prophylactic measures of hemorrhage were allowed in predefined cases. AEs ...

journal_title：World journal of gastroenterology

authors： Córdova H,Argüello L,Loras C,Naranjo Rodríguez A,Riu Pons F,Gornals JB,Nicolás-Pérez D,Andújar Murcia X,Hernández L,Santolaria S,Leal C,Pons C,Pérez-Cuadrado-Robles E,García-Bosch O,Papo Berger M,Ulla Rocha JL,Sánchez-Mon

更新日期：2017-12-21 00:00:00

abstract：AIM:To assess the practice of caring for acute liver failure (ALF) patients in varying geographic locations and medical centers. METHODS:Members of the European Acute Liver Failure Consortium completed an 88-item questionnaire detailing management of ALF. Responses from 22 transplantation centers in 11 countries were ...

journal_title：World journal of gastroenterology

authors： Rabinowich L,Wendon J,Bernal W,Shibolet O

更新日期：2016-09-07 00:00:00

abstract：:Following the international guidelines criteria an adequate "diagnostic conclusion" of inflammatory bowel disease (IBD) can be achieved only if clinical, endoscopic and laboratory findings, together with sample technical adequacy and unequivocal histomorphological signs of the disease are available. Thus, a conclusive...

journal_title：World journal of gastroenterology

authors： Canavese G,Bassotti G,Astegiano M,Castellano I,Cassoni P,Sapino A,Villanacci V

更新日期：2013-01-21 00:00:00

abstract：:Colorectal cancer (CRC) is one of the commonest cancers with 1.2 million new cases diagnosed each year in the world. It remains the fourth most common cause of cancer-related mortality in the world and accounts for > 600000 cancer-related deaths each year. There have been significant advances in treatment of metastati...

journal_title：World journal of gastroenterology

authors： Khan K,Wale A,Brown G,Chau I

更新日期：2014-09-21 00:00:00

abstract：AIM:To evaluate the long-term efficacy and safety of endoscopic obliteration with Histoacryl(®) for treatment of gastric variceal bleeding and prophylaxis. METHODS:Between January 1994 and March 2010 at SoonChunHyang University Hospital, a total of 127 patients with gastric varices received Histoacryl(®) injections en...

journal_title：World journal of gastroenterology

authors： Kang EJ,Jeong SW,Jang JY,Cho JY,Lee SH,Kim HG,Kim SG,Kim YS,Cheon YK,Cho YD,Kim HS,Kim BS

更新日期：2011-03-21 00:00:00

abstract：AIM:Chemokines and their receptors are crucial for immune responses in HCV and HIV infection. RANTES gene polymorphisms lead to altered gene expression and influence the natural course of HIV infection. Therefore, these mutations may also affect the course of HIV/HCV coinfection. METHODS:We determined allele frequenci...

journal_title：World journal of gastroenterology

authors： Ahlenstiel G,Iwan A,Nattermann J,Bueren K,Rockstroh JK,Brackmann HH,Kupfer B,Landt O,Peled A,Sauerbruch T,Spengler U,Woitas RP

更新日期：2005-12-28 00:00:00

abstract：:It is one of the most important problems for general surgeons to decide which operation should be undertaken on patients with intra-abdominal infection, especially those with concomitant abdominal hypertension. Recently, closure techniques using prosthetic meshes in order to retain abdominal tension and to control sep...

journal_title：World journal of gastroenterology

authors： Tekin S,Tekin A,Kucukkartallar T,Cakir M,Kartal A

更新日期：2008-02-07 00:00:00

abstract：:Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease characterized by progressive fibroinflammatory destruction of the intra- and/or extrahepatic biliary ducts. While its features and disease course can be variable, most patients with PSC have concurrent inflammatory bowel disease and will eventual...

journal_title：World journal of gastroenterology

authors： Fung BM,Lindor KD,Tabibian JH

更新日期：2019-02-14 00:00:00

abstract：AIM:To investigate the therapeutic effects of mesenchymal stem cells (MSCs) transplanted intraperitoneally and intravenously in a murine model of colitis. METHODS:MSCs were isolated from C57BL/6 mouse adipose tissue. MSC cultures were analyzed according to morphology, cellular differentiation potential, and surface mo...

journal_title：World journal of gastroenterology

authors： Gonçalves Fda C,Schneider N,Pinto FO,Meyer FS,Visioli F,Pfaffenseller B,Lopez PL,Passos EP,Cirne-Lima EO,Meurer L,Paz AH

更新日期：2014-12-28 00:00:00

abstract：:Redox state constitutes an important background of numerous liver disorders. The redox state participates in the course of inflammatory, metabolic and proliferative liver diseases. Reactive oxygen species (ROS) are primarily produced in the mitochondria and in the endoplasmic reticulum of hepatocytes via the cytochrom...

journal_title：World journal of gastroenterology

authors： Cichoż-Lach H,Michalak A

更新日期：2014-07-07 00:00:00

abstract：AIM:To evaluate the prognostic power of different molecular data in liver cancer. METHODS:Cox regression screen and least absolute shrinkage and selection operator were performed to select significant prognostic variables. Then the concordance index was calculated to evaluate the prognostic power. For the combination ...

journal_title：World journal of gastroenterology

authors： Song YZ,Li X,Li W,Wang Z,Li K,Xie FL,Zhang F

更新日期：2018-07-28 00:00:00

abstract：AIM:To construct tree models for classification of diffuse large B-cell lymphomas (DLBCL) by chromosome copy numbers, to compare them with cDNA microarray classification, and to explore models of multi-gene, multi-step and multi-pathway processes of DLBCL tumorigenesis. METHODS:Maximum-weight branching and distance-ba...

journal_title：World journal of gastroenterology

authors： Jiang HY,Huang ZX,Zhang XF,Desper R,Zhao T

更新日期：2007-03-21 00:00:00