Clinicopathological significance of LRP16 protein in 336 gastric carcinoma patients.

abstract：:More than five years ago, the treatment of hepatitis C virus infection was revolutionized with the introduction of all-oral direct-acting antiviral (DAA) drugs. They proved highly efficient in curing patients with chronic hepatitis C (CHC), including patients with cirrhosis. The new DAA treatments were alleged to indu...

journal_title：World journal of gastroenterology

authors： Laursen TL,Sandahl TD,Kazankov K,George J,Grønbæk H

更新日期：2020-06-14 00:00:00

abstract：:Helicobacter pylori (H. pylori) is a well-known human pathogen that plays an essential role in the pathogenesis of chronic gastritis, peptic ulcer disease, and gastric malignancies. Although H. pylori is susceptible to several antimicrobials, this infection has proven challenging to cure because of the increasing prev...

journal_title：World journal of gastroenterology

authors： Federico A,Gravina AG,Miranda A,Loguercio C,Romano M

更新日期：2014-01-21 00:00:00

abstract：AIM:To investigate the role of nuclear factor-kappaB (NF-kappaB) inhibitor caffeic acid phenethy1 ester (CAPE) in the proliferation, collagen synthesis and apoptosis of hepatic stellate cells (HSCs) of rats. METHODS:The HSCs from rats were isolated and cultured in Dulbecco's Modified Eagle's Medium (DMEM) and treated ...

journal_title：World journal of gastroenterology

authors： Zhao WX,Zhao J,Liang CL,Zhao B,Pang RQ,Pan XH

更新日期：2003-06-01 00:00:00

abstract：AIM:To determine the association of circulating miR-125a/b expression with the risk and disease severity of Crohn's disease (CD), and with inflammatory cytokines. METHODS:Plasma samples were collected from patients with active CD (A-CD), or CD in remission (R-CD) and from healthy controls (HCs). The levels of the infl...

journal_title：World journal of gastroenterology

authors： Sun CM,Wu J,Zhang H,Shi G,Chen ZT

更新日期：2017-11-28 00:00:00

abstract：AIM:To evaluate the role of miniprobe ultrasonography under colonoscope in the diagnosis of submucosal tumor of the large intestine, and to determine its imaging characteristics. METHODS:Thirty-five patients with submucosal tumors of the large intestine underwent miniprobe ultrasonography under colonoscope. The diagno...

journal_title：World journal of gastroenterology

authors： Zhou PH,Yao LQ,Zhong YS,He GJ,Xu MD,Qin XY

更新日期：2004-08-15 00:00:00

abstract：AIM:To construct a DNA vaccine against extracellular domains 1-3 of fetal liver kinase-1 (flk-1), and to investigate its preventive and therapeutic effect against H22 cell in vivo. METHODS:Flk-1 DNA vaccine was produced by cloning extracellular domains 1-3 of flk-1 and by inserting the cloned gene into pcDNA3.1 (+). F...

journal_title：World journal of gastroenterology

authors： Lü F,Qin ZY,Yang WB,Qi YX,Li YM

更新日期：2004-07-15 00:00:00

abstract：AIM:To investigate the incidence, characteristics, and risk factors for hepatocellular carcinoma (HCC) in Chinese patients with primary biliary cirrhosis (PBC). METHODS:We reviewed the data of 52 PBC-associated HCC patients treated at Beijing 302 Hospital from January 2002 to December 2013 and analyzed its incidence a...

journal_title：World journal of gastroenterology

authors： Zhang XX,Wang LF,Jin L,Li YY,Hao SL,Shi YC,Zeng QL,Li ZW,Zhang Z,Lau GK,Wang FS

更新日期：2015-03-28 00:00:00

abstract：:Colorectal cancer metastasizes predictably, with liver predominance in most cases. Because liver involvement has been shown to be a major determinant of survival in this population, liver-directed therapies are increasingly considered even in cases where there is (limited) extrahepatic disease. Unfortunately, these pa...

journal_title：World journal of gastroenterology

authors： Sag AA,Selcukbiricik F,Mandel NM

更新日期：2016-03-21 00:00:00

abstract：AIM:To evaluate the proinflammatory effects and molecular mechanisms of interleukin (IL)-17 in intestinal epithelial cell line HT-29. METHODS:HT-29 cells were cultured with IL-17, tumor necrosis factor (TNF)-α, or the combination of both IL-17 and TNF-α. Real-time PCR and Western blot were used to measure the gene exp...

journal_title：World journal of gastroenterology

authors： Wang YL,Fang M,Wang XM,Liu WY,Zheng YJ,Wu XB,Tao R

更新日期：2014-12-21 00:00:00

abstract：AIM:To investigate the diagnostic significance of transient elastography (TE) in a daily routine clinical setting in comparison to clinical signs, laboratory parameters and ultrasound. METHODS:TE, ultrasound, laboratory parameters and cutaneous liver signs were assessed in 291 consecutive patients with chronic liver d...

journal_title：World journal of gastroenterology

authors： Göbel T,Schadewaldt-Tümmers J,Greiner L,Poremba C,Häussinger D,Erhardt A

更新日期：2015-01-21 00:00:00

abstract：:One 63-year-old woman, who presented with cholestatic jaundice due to common bile duct compression produced by primary retroperitoneal fibrosis, is studied. The patient was operated six years ago because of hydronephrosis, when the disease was first diagnosed. Magnetic resonance cholangiopancreatography (MRCP) reveale...

journal_title：World journal of gastroenterology

authors： Zhao MF,Tian Y,Guo KJ,Ma ZG,Liao HH

更新日期：2004-10-15 00:00:00

abstract：:Primary hepatic neuroendocrine carcinoma (NEC) with concurrent occurrence of hepatocellular carcinoma (HCC) of the liver is very rare. Only 8 cases have been reported in the literature. Concurrent occurrence of HCC and NEC in the liver is classified as combined type or collision type by histological distributional pat...

journal_title：World journal of gastroenterology

authors： Choi GH,Ann SY,Lee SI,Kim SB,Song IH

更新日期：2016-11-07 00:00:00

abstract：:Hepatitis C virus (HCV) infection induces steatosis and is accompanied by multiple metabolic alterations including hyperuricemia, reversible hypocholesterolemia and insulin resistance. Total cholesterol, low-density lipoprotein-cholesterol and triglyceride levels are increased by peginterferon and ribavirin combinatio...

journal_title：World journal of gastroenterology

authors： Kanda T,Moriyama M

更新日期：2017-08-21 00:00:00

abstract：:Cytomegalovirus (CMV) infection is a common complication after liver transplantation, and it is associated with multiple direct and indirect effects. Management of CMV infection and disease has evolved over the years, and clinical guidelines have been recently updated. Universal antiviral prophylaxis and a pre-emptive...

journal_title：World journal of gastroenterology

authors： Marcelin JR,Beam E,Razonable RR

更新日期：2014-08-21 00:00:00

abstract：AIM:To examine the expressions of matrix metalloproteinases-2 (MMP-2) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in rat fibrotic liver and in normal rat hepatic stellate cells, and to investigate the changes in their expressions in response to treatment with interleukin-10 (IL-10) and platelet-derived growth...

journal_title：World journal of gastroenterology

authors： Zhang LJ,Chen YX,Chen ZX,Huang YH,Yu JP,Wang XZ

更新日期：2004-09-01 00:00:00

abstract：AIM:To develop a potent and safe gene therapy for esophageal cancer. METHODS:An expression vector carrying fusion suicide gene (yCDglyTK) and shRNA against vascular endothelial growth factor (VEGF) was constructed and delivered into EC9706 esophageal cancer cells by calcium phosphate nanoparticles (CPNP). To achieve t...

journal_title：World journal of gastroenterology

authors： Liu T,Wu HJ,Liang Y,Liang XJ,Huang HC,Zhao YZ,Liao QC,Chen YQ,Leng AM,Yuan WJ,Zhang GY,Peng J,Chen YH

更新日期：2016-06-21 00:00:00

abstract：:Non-HFE hereditary haemochromatosis (HH) refers to a genetically heterogeneous group of iron overload disorders that are unlinked to mutations in the HFE gene. The four main types of non-HFE HH are caused by mutations in the hemojuvelin, hepcidin, transferrin receptor 2 and ferroportin genes. Juvenile haemochromatosis...

journal_title：World journal of gastroenterology

authors： Wallace DF,Subramaniam VN

更新日期：2007-09-21 00:00:00

abstract：AIM:To determine risk factors associated with hepatitis C virus (HCV) treatment failure after direct acting antivirals in patients with complex treatment histories. METHODS:All HCV mono-infected patients who received treatment at our institution were queried. Analysis was restricted to patients who previously failed t...

journal_title：World journal of gastroenterology

authors： Hartman J,Bichoupan K,Patel N,Chekuri S,Harty A,Dieterich D,Perumalswami P,Branch AD

更新日期：2015-11-21 00:00:00

abstract：:Iatrogenic bile duct injuries (IBDI) remain an important problem in gastrointestinal surgery. They are most frequently caused by laparoscopic cholecystectomy which is one of the commonest surgical procedures in the world. The early and proper diagnosis of IBDI is very important for surgeons and gastroenterologists, be...

journal_title：World journal of gastroenterology

authors： Jabłońska B,Lampe P

更新日期：2009-09-07 00:00:00

abstract：AIM:To evaluate the expressions of apoptotic signal proteins FADD, TRADD, FasL, Fas, and NFkappaB in gastric carcinoma tissues and their clinical significance. METHODS:Western blot immune trace method was adopted to detect the expressions of apoptotic signal proteins FADD, TRADD, FasL, Fas, and NFkappaB in 55 tissue s...

journal_title：World journal of gastroenterology

authors： Zhao XH,Gu SZ,Tian HG,Quan P,Pan BR

更新日期：2005-07-07 00:00:00

abstract：BACKGROUND:Systemic inflammation and nutrition status play an important role in cancer metastasis. The combined index of hemoglobin, albumin, lymphocyte, and platelet (HALP), consisting of haemoglobin, albumin, lymphocytes, and platelets, is considered as a novel marker to reflect both systemic inflammation and nutriti...

journal_title：World journal of gastroenterology

authors： Xu SS,Li S,Xu HX,Li H,Wu CT,Wang WQ,Gao HL,Jiang W,Zhang WH,Li TJ,Ni QX,Liu L,Yu XJ

更新日期：2020-02-28 00:00:00

abstract：:The occurrence of pancreatic pleural effusion, secondary to an internal pancreatic fistula, is a rare clinical syndrome and diagnosis is often missed. The key to the diagnosis is a dramatically elevated pleural fluid amylase. This pancreatic pleural effusion is also called a pancreatic pleural fistula. It is character...

journal_title：World journal of gastroenterology

authors： Jin SG,Chen ZY,Yan LN,Zeng Y

更新日期：2010-09-21 00:00:00

abstract：:The major type of human liver cancer is hepatocellular carcinoma (HCC), and there are currently many risk factors that contribute to this deadly disease. The majority of HCC occurrences are associated with chronic hepatitis viral infection, and hepatitis B viral (HBV) infection is currently a major health problem in E...

journal_title：World journal of gastroenterology

authors： Chiu AP,Tschida BR,Lo LH,Moriarity BS,Rowlands DK,Largaespada DA,Keng VW

更新日期：2015-11-14 00:00:00

abstract：:Liver transplantation for human immunodeficiency virus (HIV) positive patients with viral hepatitis co-infection is increasingly offered in many North American and European liver transplant centers. Prior studies have demonstrated acceptable post-transplant outcomes and no increased risk of HIV complications in patien...

journal_title：World journal of gastroenterology

authors： Congly SE,Doucette KE,Coffin CS

更新日期：2014-01-14 00:00:00

abstract：:We report the case of a 57-year-old man who was diagnosed with a large unresectable cholangiocarcinoma associated with 2 satellite nodules and without clear margins with the right hepatic vein. Despite 4 cycles of GEMOX (stopped due to a hypertransaminasemia believed to be due to gemcitabine) and 4 cycles of FOLFIRINO...

journal_title：World journal of gastroenterology

authors： Servajean C,Gilabert M,Piana G,Monges G,Delpero JR,Brenot I,Raoul JL

更新日期：2014-05-07 00:00:00

abstract：:Microsomal glutathione transferase (MGST1, EC 2.5.1.18) is a membrane bound glutathione transferase extensively studied for its ability to detoxify reactive intermediates, including metabolic electrophile intermediates and lipophilic hydroperoxides through its glutathione dependent transferase and peroxidase activitie...

journal_title：World journal of gastroenterology

authors： Schaffert CS

更新日期：2011-05-28 00:00:00

abstract：:Chronic intake of alcohol undoubtedly overwhelms the structural and functional capacity of the liver by initiating complex pathological events characterized by steatosis, steatohepatitis, hepatic fibrosis and cirrhosis. Subsequently, these initial pathological events are sustained and ushered into a more complex and p...

journal_title：World journal of gastroenterology

authors： Boye A,Zou YH,Yang Y

更新日期：2016-01-07 00:00:00

abstract：:The Da Vinci Surgical System may help to overcome some of the difficulties of laparoscopy for complicated abdominal surgery. The authors of this article present a case of robot-assisted, one-stage radical resection of three tumors, including robotic anterior resection for rectal cancer, segmental hepatectomy for liver...

journal_title：World journal of gastroenterology

authors： Xu JM,Wei Y,Wang XY,Fan H,Chang WJ,Ren L,Jiang W,Fan J,Qin XY

更新日期：2015-03-07 00:00:00

abstract：AIM:To evaluate the efficacy of short-term overlap lamivudine therapy with adefovir in patients with lamivudine-resistant and naive chronic hepatitis B, we compared patients receiving overlap therapy with those receiving adefovir alone. METHODS:Eighty patients who had received lamivudine treatment for various periods ...

journal_title：World journal of gastroenterology

authors： Nam SW,Bae SH,Lee SW,Kim YS,Kang SB,Choi JY,Cho SH,Yoon SK,Han JY,Yang JM,Lee YS

更新日期：2008-03-21 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the fourth cause of cancer related mortality, and its incidence is rapidly increasing. Viral hepatitis, alcohol abuse, and exposure to hepatotoxins are major risk factors, but nonalcoholic fatty liver disease (NAFLD) associated with obesity, insulin resistance, and type 2 diabetes, is...

journal_title：World journal of gastroenterology

authors： Dongiovanni P,Romeo S,Valenti L

更新日期：2014-09-28 00:00:00