Outcomes and management of viral hepatitis and human immunodeficiency virus co-infection in liver transplantation.

Abstract:

:Liver transplantation for human immunodeficiency virus (HIV) positive patients with viral hepatitis co-infection is increasingly offered in many North American and European liver transplant centers. Prior studies have demonstrated acceptable post-transplant outcomes and no increased risk of HIV complications in patients co-infected with hepatitis B virus (HBV). However, liver transplantation in HIV positive patients with hepatitis C virus (HCV) has poorer outcomes overall, requiring careful selection of candidates. This review aims to summarize the published literature on outcomes after transplant in HIV patients with HBV or HCV related end-stage liver disease and recommendations for management. In particular the pre-transplant factors impacting outcomes in HCV/HIV co-infected candidates and importance of multidisciplinary management will be discussed.

journal_name

World J Gastroenterol

authors

Congly SE,Doucette KE,Coffin CS

doi

10.3748/wjg.v20.i2.414

subject

Has Abstract

pub_date

2014-01-14 00:00:00

pages

414-24

issue

2

eissn

1007-9327

issn

2219-2840

journal_volume

20

pub_type

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