Therapeutic procedures for submucosal tumors in the gastrointestinal tract.

Abstract:

:This review is part three of three and will present an update on the therapeutic options and procedures concerning gastrointestinal (GI) submucosal tumors (SMTs). The aim of this paper is to investigate the treatments of GI SMTs and to present a case of a gastrointestinal stromal tumor (GIST). Literature searches were performed to find information on therapy for GI SMTs. Based on these searches, the optimal therapeutic procedures could be outlined. The choice of treatment of localized tumors is endoscopic resection if possible or, alternatively, laparoscopic resection or surgical resection by an open procedure. However, benign SMTs should only be excised if symptoms are present, and GISTs should be treated with particular precautions. Irresectable or recurrent GISTs may be successfully treated with the tyrosine kinase inhibitor, imatinib.

journal_name

World J Gastroenterol

authors

Ponsaing LG,Hansen MB

doi

10.3748/wjg.v13.i24.3316

subject

Has Abstract

pub_date

2007-06-28 00:00:00

pages

3316-22

issue

24

eissn

1007-9327

issn

2219-2840

journal_volume

13

pub_type

杂志文章,评审
  • Management and associated factors of delayed perforation after gastric endoscopic submucosal dissection.

    abstract:AIM:To identify the actual clinical management and associated factors of delayed perforation after gastric endoscopic submucosal dissection (ESD). METHODS:A total of 4943 early gastric cancer (EGC) patients underwent ESD at our hospital between January 1999 and June 2012. We retrospectively assessed the actual managem...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i44.12635

    authors: Suzuki H,Oda I,Sekiguchi M,Abe S,Nonaka S,Yoshinaga S,Nakajima T,Saito Y

    更新日期:2015-11-28 00:00:00

  • Immunohistochemical assessment of NY-ESO-1 expression in esophageal adenocarcinoma resection specimens.

    abstract:AIM:To assess NY-ESO-1 expression in a cohort of esophageal adenocarcinomas. METHODS:A retrospective search of our tissue archive for esophageal resection specimens containing esophageal adenocarcinoma was performed, for cases which had previously been reported for diagnostic purposes, using the systematised nomenclat...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i14.4011

    authors: Hayes SJ,Hng KN,Clark P,Thistlethwaite F,Hawkins RE,Ang Y

    更新日期:2014-04-14 00:00:00

  • Intensive or not surveillance of patients with colorectal cancer after curative resection.

    abstract::It is common practice to follow patients with colorectal cancer for some years after resection and/or adjuvant treatment. Data are lacking about how often patients should be seen, what tests should be performed, and what surveillance strategy has a significant impact on patient outcome. Seven randomized trials have ad...

    journal_title:World journal of gastroenterology

    pub_type: 社论

    doi:10.3748/wjg.v16.i12.1427

    authors: Rosati G

    更新日期:2010-03-28 00:00:00

  • Factors that impact health-related quality of life in adults with celiac disease: a multicenter study.

    abstract:AIM:To evaluate the factors involved in the impairment of health-related quality of life (HRQOL) in patients with celiac disease. METHODS:A multicenter, cross-sectional prospective study was performed in patients with celiac disease who completed two HRQOL questionnaires: the gastrointestinal quality of life index (GI...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.14.46

    authors: Casellas F,Rodrigo L,Vivancos JL,Riestra S,Pantiga C,Baudet JS,Junquera F,Diví VP,Abadia C,Papo M,Gelabert J,Malagelada JR

    更新日期:2008-01-07 00:00:00

  • Successful treatment of giant rectal varices by modified percutaneous transhepatic obliteration with sclerosant: Report of a case.

    abstract::We present a female patient with continuous melena, diagnosed with rectal variceal bleeding. She had a history of esophageal varices, which were treated with endoscopic therapy. Five years after the treatment of esophageal varices, continuous melena occurred. Since colonoscopy showed that the melena was caused by gian...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i33.5408

    authors: Okazaki H,Higuchi K,Shiba M,Nakamura S,Wada T,Yamamori K,Machida A,Kadouchi K,Tamori A,Tominaga K,Watanabe T,Fujiwara Y,Nakamura K,Arakawa T

    更新日期:2006-09-07 00:00:00

  • Effect of fermented soy milk on the intestinal bacterial ecosystem.

    abstract:AIM:To investigate the effect of fermented soy milk on human ecosystem in the intestinal tract by way of examining the population of different microorganisms isolated from fecal samples. METHODS:A crossover experimental design was applied. Twenty-eight healthy adults completed this experiment. Each subject consumed 25...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3748/wjg.v11.i8.1225

    authors: Cheng IC,Shang HF,Lin TF,Wang TH,Lin HS,Lin SH

    更新日期:2005-02-28 00:00:00

  • Noninvasive assessment of liver fibrosis with combined serum aminotransferase/platelet ratio index and hyaluronic acid in patients with chronic hepatitis B.

    abstract:AIM:To construct a noninvasive assessment model consisting of routine laboratory data to predict significant fibrosis and cirrhosis in patients with chronic hepatitis B (CHB). METHODS:A total of 137 consecutive patients with CHB who underwent percutaneous liver biopsy were retrospectively analyzed. These patients were...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.7117

    authors: Zhang YX,Wu WJ,Zhang YZ,Feng YL,Zhou XX,Pan Q

    更新日期:2008-12-14 00:00:00

  • Chronic pancreatitis as presentation of Crohn's disease in a child.

    abstract::It is reported that a pancreatic disease may precede the diagnosis of inflammatory bowel disease (IBD) both in children and in adults. Idiopathic chronic pancreatitis, however, occasionally co-exists with the IBD, mainly at pediatric age. We report a case of a patient who progressively developed the features of a chro...

    journal_title:World journal of gastroenterology

    pub_type: 信件

    doi:10.3748/wjg.v19.i31.5204

    authors: Knafelz D,Panetta F,Monti L,Bracci F,Papadatou B,Torre G,Dall'Oglio L,Diamanti A

    更新日期:2013-08-21 00:00:00

  • Screening for pancreatic cancer in familial high-risk individuals: A systematic review.

    abstract:AIM:To analyze the benefits and harms of pancreatic cancer screening in familial high-risk individuals (HRIs). METHODS:Studies were identified by searching PubMed, EBSCO, ClinicalTrials.gov and the Cochrane database from database inception to June 2014. We also obtained papers from the reference lists of pertinent stu...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v21.i28.8678

    authors: Lu C,Xu CF,Wan XY,Zhu HT,Yu CH,Li YM

    更新日期:2015-07-28 00:00:00

  • High circulating tumor cell concentrations in a specific subtype of gastric cancer with diffuse bone metastasis at diagnosis.

    abstract:AIM:To clarify the biological feature contributing to gastric cancer with diffuse bone metastases at diagnosis. METHODS:The participants visited the Department of Clinical Oncology, Akita University Hospital, from January 2014 to August 2015. The selection criterion for gastric cancer with diffuse bone metastases at d...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i26.6083

    authors: Shimazu K,Fukuda K,Yoshida T,Inoue M,Shibata H

    更新日期:2016-07-14 00:00:00

  • Green tea and the risk of gastric cancer: epidemiological evidence.

    abstract::Gastric cancer (GC) is one of the leading causes of cancer death in the world. Numerous efforts are being made to find chemoprotective agents able to reduce its risk. Amongst these, green tea has been reported to have a protective effect against stomach cancer. This article aims to critically evaluate all epidemiologi...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.v19.i24.3713

    authors: Hou IC,Amarnani S,Chong MT,Bishayee A

    更新日期:2013-06-28 00:00:00

  • Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon.

    abstract::Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions are well established biological events which have an important role in not just normal tissue and organ development, but in the pathogenesis of diseases. Increasing evidence has established their presence in the human colon during colorectal carcinoge...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.v18.i7.601

    authors: Sipos F,Galamb O

    更新日期:2012-02-21 00:00:00

  • Prognostic value of innate and adaptive immunity in colorectal cancer.

    abstract::Colorectal cancer (CRC) remains one of the major public health problems throughout the world. Originally depicted as a multi-step dynamical disease, CRC develops slowly over several years and progresses through cytologically distinct benign and malignant states, from single crypt lesions through adenoma, to malignant ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v19.i2.174

    authors: Grizzi F,Bianchi P,Malesci A,Laghi L

    更新日期:2013-01-14 00:00:00

  • 1alpha, 25-dihydroxyvitamin D3 prevents DNA damage and restores antioxidant enzymes in rat hepatocarcinogenesis induced by diethylnitrosamine and promoted by phenobarbital.

    abstract:AIM:To investigate the chemopreventive effects of 1alpha, 25-dihydroxyvitamin D(3) in diethylnitrosamine induced, phenobarbital promoted rat hepatocarcinogenesis. METHODS:The rats were randomly divided into 6 different groups (A-F). Groups A, C and E rats received a single intraperitoneal (i.p.) injection of diethylni...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i9.1268

    authors: Banakar MC,Paramasivan SK,Chattopadhyay MB,Datta S,Chakraborty P,Chatterjee M,Kannan K,Thygarajan E

    更新日期:2004-05-01 00:00:00

  • Antifibrotic effects of green tea on in vitro and in vivo models of liver fibrosis.

    abstract:AIM:To examine the protective effect of green tea extract (GT) on hepatic fibrosis in vitro and in vivo in dimethylnitrosamine (DMN)-induced rats. METHODS:HSC-T6, a rat hepatic stellate cell line, was used as an in vitro assay system. Cell proliferation, collagen content, and type 1 collagen expression were examined i...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.5200

    authors: Kim HK,Yang TH,Cho HY

    更新日期:2009-11-07 00:00:00

  • Possible causes of central pontine myelinolysis after liver transplantation.

    abstract:AIM:To sum up the clinical characteristics of patients with central pontine myelinolysis (CPM) after orthotopic liver transplantation (OLT) and to document the possible causes of CPM. METHODS:Data of 142 patients undergoing OLT between January 1999 to May 2003 were analyzed retrospectively. Following risk factors duri...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i17.2540

    authors: Yu J,Zheng SS,Liang TB,Shen Y,Wang WL,Ke QH

    更新日期:2004-09-01 00:00:00

  • Protective effects of panax notoginseng saponin on dextran sulfate sodium-induced colitis in rats through phosphoinositide-3-kinase protein kinase B signaling pathway inhibition.

    abstract:BACKGROUND:Intestinal inflammation is a common digestive tract disease, which is usually treated with hormone medicines. Hormone medicines are effective to some extent, but long-term use of them may bring about many complications. AIM:To explore the protective effects of panax notoginseng saponin (PNS) against dextran...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v26.i11.1156

    authors: Lu QG,Zeng L,Li XH,Liu Y,Du XF,Bai GM,Yan X

    更新日期:2020-03-21 00:00:00

  • Zebrafish as a disease model for studying human hepatocellular carcinoma.

    abstract::Liver cancer is one of the world's most common cancers and the second leading cause of cancer deaths. Hepatocellular carcinoma (HCC), a primary hepatic cancer, accounts for 90%-95% of liver cancer cases. The pathogenesis of HCC consists of a stepwise process of liver damage that extends over decades, due to hepatitis,...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v21.i42.12042

    authors: Lu JW,Ho YJ,Yang YJ,Liao HA,Ciou SC,Lin LI,Ou DL

    更新日期:2015-11-14 00:00:00

  • Strangulated diaphragmatic hernia presenting clinically as pericarditis.

    abstract::A case of strangulation of the transverse colon in a traumatic left diaphragmatic hernia manifesting as pericarditis is reported. This is unusual because pericardial signs in traumatic diaphragmatic hernia have been previously described in association with direct pericardial injury. This is the only such case where el...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i9.1449

    authors: Makhija R,Akoh JA

    更新日期:2007-03-07 00:00:00

  • T cell immune response is correlated with fibrosis and inflammatory activity in hepatitis B cirrhotics.

    abstract:AIM:To explore the relationship among interferon-gamma (IFN-gamma) activity, fibrogenesis, T cell immune responses and hepatic inflammatory activity. METHODS:Peripheral blood samples from a total of 43 hepatitis B cirrhotic patients (LC) and 19 healthy controls (NC) were collected to measure their serum levels of IFN-...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i19.3015

    authors: Tang JT,Fang JY,Gu WQ,Li EL

    更新日期:2006-05-21 00:00:00

  • Effects of Changtai granules, a traditional compound Chinese medicine, on chronic trinitrobenzene sulfonic acid-induced colitis in rats.

    abstract:AIM:To study the effects of Changtai granules (CTG), a traditional compound Chinese medicine, on chronic trinitrobenzene sulfonic acid-induced colitis in rats. METHODS:Healthy adult Sprague-Dawley (SD) rats of both sexes, weighing 250-300 g, were employed in the present study. The rat colitis models were induced by 2,...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i23.3539

    authors: Cao YB,Zhang JD,Diao YY,Yan L,Wang DJ,Jia XM,Gao PH,Cheng MH,Xu Z,Wang Y,Jiang YY

    更新日期:2005-06-21 00:00:00

  • Superior mesenteric artery syndrome following scoliosis surgery: its risk indicators and treatment strategy.

    abstract:AIM:To investigate the risk indicators, pattern of clinical presentation and treatment strategy of superior mesenteric artery syndrome (SMAS) after scoliosis surgery. METHODS:From July 1997 to October 2003, 640 patients with adolescent scoliosis who had undergone surgical treatment were evaluated prospectively, and am...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i21.3307

    authors: Zhu ZZ,Qiu Y

    更新日期:2005-06-07 00:00:00

  • Duodenal variceal bleeding after balloon-occluded retrograde transverse obliteration: treatment with transjugular intrahepatic portosystemic shunt.

    abstract::We report a case of duodenal varix bleeding as a long term complication of balloon occluded retrograde transvenous obliteration (BRTO), which was successfully treated with a transjugular intrahepatic portosystemic shunt (TIPS). A 57-year-old man was admitted to the emergency room suffering from melena. He had undergon...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i22.2877

    authors: Kim MJ,Jang BK,Chung WJ,Hwang JS,Kim YH

    更新日期:2012-06-14 00:00:00

  • Unconjugated bilirubin alleviates experimental ulcerative colitis by regulating intestinal barrier function and immune inflammation.

    abstract:BACKGROUND:Unconjugated bilirubin (UCB) is generally considered toxic but has gained recent prominence for its anti-inflammatory properties. However, the effects of it on the interaction between intestinal flora and organisms and how it influences immune responses remain unresolved. AIM:To investigate the role of UCB ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v25.i15.1865

    authors: Zheng JD,He Y,Yu HY,Liu YL,Ge YX,Li XT,Li X,Wang Y,Guo MR,Qu YL,Qin XF,Jiang MS,Wang XH

    更新日期:2019-04-21 00:00:00

  • Contribution of mammalian target of rapamycin in the pathophysiology of cirrhotic cardiomyopathy.

    abstract:AIM:To explore the role of mammalian target of rapamycin (mTOR) in the pathogenesis of cirrhotic cardiomyopathy and the potential of rapamycin to improve this pathologic condition. METHODS:Male albino Wistar rats weighing 100-120 g were treated with tetrachloride carbon (CCl4) for 8 wk to induce cirrhosis. Subsequentl...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i19.4685

    authors: Saeedi Saravi SS,Ghazi-Khansari M,Ejtemaei Mehr S,Nobakht M,Mousavi SE,Dehpour AR

    更新日期:2016-05-21 00:00:00

  • Clear cell colitis: a form of microscopic colitis in children.

    abstract:AIM:To describe a new clinical and pathological subtype of microscopic colitis in children. METHODS:A selected group of children with abdominal pain, constipation and/or diarrhoea showing discrete or no macroscopic abnormalities on endoscopy was described. RESULTS:Multiple biopsies of colon showed large mononuclear c...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.231

    authors: Józefczuk J,Wozniewicz BM

    更新日期:2008-01-14 00:00:00

  • Treatment for superficial non-ampullary duodenal epithelial tumors.

    abstract::Because of the low prevalence of non-ampullary duodenal epithelial tumors (NADETs), standardized clinical management of sporadic superficial NADETs, including diagnosis, treatment, and follow-up, has not yet been established. Retrospective studies have revealed certain endoscopic findings suggestive of malignancy. Duo...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i35.12501

    authors: Kakushima N,Kanemoto H,Tanaka M,Takizawa K,Ono H

    更新日期:2014-09-21 00:00:00

  • Differences in characteristics of colorectal neoplasm between young and elderly Thais.

    abstract:AIM:To analyze the differences of clinical characteristics of colorectal neoplasm including polyps between the elderly and young Thai patients. METHODS:Colonoscopy database from December 2000 to October 2004 was retrospectively analyzed. There were 1822 eligible patients who underwent colonoscopy (with a mean age of 5...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i47.7684

    authors: Rerknimitr R,Ratanapanich W,Kongkam P,Kullavanijaya P

    更新日期:2006-12-21 00:00:00

  • Human papillomavirus does not have a causal role in colorectal carcinogenesis.

    abstract:AIM:To investigate the presence of human papillomavirus (HPV) DNA along with the integration, the quantification and the expression of the HPV16 in colorectal cancers. METHODS:A prospective series of colorectal tumors were genotyped for HPV DNA. The clinical and pathological variables of the HPV-positive tumors were c...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i1.342

    authors: Lorenzon L,Mazzetta F,Pilozzi E,Uggeri G,Torrisi MR,Ferri M,Ziparo V,French D

    更新日期:2015-01-07 00:00:00

  • Elevated risk for gastric adenocarcinoma can be predicted from histomorphology.

    abstract::The number of patients with gastric cancer has more than doubled since 1985 in developing countries. Thus, the questions of whether it can be predicted from gastritis morphology, who is at risk and who has a lower risk of developing gastric carcinoma are raised. H pylori-infection leads to erosions, ulcerations, carci...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v12.i38.6109

    authors: Vieth M,Stolte M

    更新日期:2006-10-14 00:00:00