Effect of insulin-sensitizing agents in combination with ezetimibe, and valsartan in rats with non-alcoholic fatty liver disease.

abstract：:To our knowledge, stercoral perforation of the colon is rarely seen with fewer than 90 cases reported in the literature till date. We explored the principles of management to prevent impending mortality in five patients with this condition. Five patients, two males and three females, whose median age was 64 years, had...

journal_title：World journal of gastroenterology

authors： Huang WS,Wang CS,Hsieh CC,Lin PY,Chin CC,Wang JY

更新日期：2006-01-21 00:00:00

abstract：AIM:To investigate the location alteration of Smad2 and Smad4 mRNAs in the liver during and after fibrogenesis in rats. METHODS:Eighty male Wistar rats weighing approximately 200 g each were used. The rat models of experimental hepatic fibrosis were established by injection with carbon tetrachloride (CCl4), normal rat...

journal_title：World journal of gastroenterology

authors： Liu Y,Wang LF,Zou HF,Song XY,Xu HF,Lin P,Zheng HH,Yu XG

更新日期：2006-03-14 00:00:00

abstract：:Intratumoral heterogeneity including genetic and nongenetic mechanisms refers to biological differences amongst malignant cells originated within the same tumor. Both, cell differentiation hierarchy and stochasticity in gene expression and signaling pathways may result in phenotypic differences of cancer cells. Since ...

journal_title：World journal of gastroenterology

authors： Sipos F,Constantinovits M,Műzes G

更新日期：2014-03-14 00:00:00

abstract：AIM:To examine the calcium metabolism of colorectal cancer (CRC) in patients with colorectal cancer and control patients. METHODS:Seventy newly diagnosed CRC patients were included. The healthy control group was age and gender matched (n=32). Particular attention was devoted to the relationship between serum calcium o...

journal_title：World journal of gastroenterology

authors： Fuszek P,Lakatos P,Tabak A,Papp J,Nagy Z,Takacs I,Horvath HC,Lakatos PL,Speer G

更新日期：2004-07-01 00:00:00

abstract：:Reduction of low-density lipoprotein-cholesterol through statin therapy has only modestly decreased coronary heart disease (CHD)-associated mortality in developed countries, which has prompted the search for alternative therapeutic strategies for CHD. Major efforts are now focused on therapies that augment high-densit...

journal_title：World journal of gastroenterology

authors： Temel RE,Brown JM

更新日期：2010-12-21 00:00:00

abstract：AIM:To compare the efficacy of different chemotherapeutic agents during conventional transarterial chemoembolization (cTACE) in the treatment of unresectable hepatocellular carcinoma (HCC). METHODS:A retrospective review was undertaken of patients with unresectable HCC undergoing cTACE from May 2003 to November 2011. ...

journal_title：World journal of gastroenterology

authors： Wu J,Song L,Zhao DY,Guo B,Liu J

更新日期：2014-08-21 00:00:00

abstract：AIM:To investigate the prognostic impact of the metastatic lymph node ratio (MLR) in advanced gastric cancer from the cardia and fundus. METHODS:Two hundred and thirty-six patients with gastric cancer from the cardia and fundus who underwent D2 curative resection were analyzed retrospectively. The correlations between...

journal_title：World journal of gastroenterology

authors： Huang CM,Lin BJ,Lu HS,Zhang XF,Li P,Xie JW

更新日期：2008-07-21 00:00:00

abstract：AIM:To assess the diagnostic value of a laparoscopic finding of a hepatic subcapsular spider-like telangiectasis (HSST) sign in biliary atresia. METHODS:A retrospective study was conducted first and then a validation set was used to investigate the value of an HSST sign in predicting biliary atresia (BA). In the retro...

journal_title：World journal of gastroenterology

authors： Zhou Y,Jiang M,Tang ST,Yang L,Zhang X,Yang DH,Xiong M,Li S,Cao GQ,Wang Y

更新日期：2017-10-21 00:00:00

abstract：AIM:To investigate and characterise patients with chronic hepatitis C virus (HCV) infection presenting with hepatocellular carcinoma (HCC) in the absence of cirrhosis. METHODS:Patients with chronic hepatitis C infection without cirrhosis presenting with HCC over a 2-year period were identified. The clinical case notes...

journal_title：World journal of gastroenterology

authors： Nash KL,Woodall T,Brown AS,Davies SE,Alexander GJ

更新日期：2010-08-28 00:00:00

abstract：AIM:To establish a visceral pain model via colorectal distension (CRD) and to evaluate the efficiency of behavioral responses of CRD by measuring the score of abdominal withdrawal reflex (AWR) in rats. METHODS:Thirty-eight male SD rats weighing 180-240 g were used to establish the visceral pain model. The rat was inse...

journal_title：World journal of gastroenterology

authors： Yang JP,Yao M,Jiang XH,Wang LN

更新日期：2006-05-07 00:00:00

abstract：AIM:Tumor angiogenesis has been shown to be promoted by vascular endothelial growth factor (VEGF) via stimulating endothelial cell proliferation, migration, and survival. Blockade of VEGF signaling by different means has been demonstrated to result in reduced tumor growth and suppression of tumor angiogenesis in distin...

journal_title：World journal of gastroenterology

authors： Schmitz V,Kornek M,Hilbert T,Dzienisowicz C,Raskopf E,Rabe C,Sauerbruch T,Qian C,Caselmann WH

更新日期：2005-07-28 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the major causes of morbidity and mortality in patients with chronic liver disease. Transarterial chemoembolization (TACE) can significantly improve the survival rate of patients with HCC and is the first treatment choice for patients who are not suitable for surgical resection...

journal_title：World journal of gastroenterology

authors： Yang K,Zhang XM,Yang L,Xu H,Peng J

更新日期：2016-05-28 00:00:00

abstract：:The aetiology of primary sclerosing cholangitis (PSC) is not known and controversy exists as to whether PSC should be denominated an autoimmune disease. A large number of autoantibodies have been detected in PSC patients, but the specificity of these antibodies is generally low, and the frequencies vary largely betwee...

journal_title：World journal of gastroenterology

authors： Hov JR,Boberg KM,Karlsen TH

更新日期：2008-06-28 00:00:00

abstract：:We here report a case of a 18-year-old man with a history of recurrent abdominal pain and a previous episode of severe acute pancreatitis. Abdominal ultrasonography, contrast enhanced multislice computer tomography, endoscopic retrograde cholangiopancreatography, endoscopic ultrasonography and magnetic resonance imagi...

journal_title：World journal of gastroenterology

authors： Guarise A,Faccioli N,Ferrari M,Romano L,Parisi A,Falconi M

更新日期：2006-03-14 00:00:00

abstract：:E2F family of transcription factors regulates various cellular functions related to cell cycle and apoptosis. Its individual members have traditionally been classified into activators and repressors, based on in vitro studies. However their contribution in human cancer is more complicated and difficult to predict. We ...

journal_title：World journal of gastroenterology

authors： Xanthoulis A,Tiniakos DG

更新日期：2013-06-07 00:00:00

abstract：AIM:To investigate the relationship between pathological oropharyngeal (OP) acid exposure and esophageal motility in patients with extra-esophageal syndromes. METHODS:In this prospective study we enrolled consecutive outpatients with extra-esophageal symptoms suspected to be related to gastroesophageal reflux disease ...

journal_title：World journal of gastroenterology

authors： Passaretti S,Mazzoleni G,Vailati C,Testoni PA

更新日期：2016-10-28 00:00:00

abstract：:Transplantation is the optimal treatment for end-stage organ failure, and modern immunosuppression has allowed important progress in short-term outcomes. However, immunosuppression poorly influences chronic rejection and elicits chronic toxicity in current clinical practice. Thus, a major goal in transplantation is to...

journal_title：World journal of gastroenterology

authors： Baroja-Mazo A,Revilla-Nuin B,Parrilla P,Martínez-Alarcón L,Ramírez P,Pons JA

更新日期：2016-09-14 00:00:00

abstract：:In this paper, we summarize the main progresses made in our group in the field of the mechanism of pigment gallstone formation. It was found that after treatment with free radicals, bilirubin (BR) was changed into free radical itself, and a semiquinone free radical and a superoxide free radical bound with metal were r...

journal_title：World journal of gastroenterology

authors： Liu XT,Hu J

更新日期：2002-06-01 00:00:00

abstract：AIM:gamma-glutamyl transpeptidase (GGT) has been reported as a virulence and colonizing factor of Helicobacter pylori (H pylori). This study examined the effect of GGT on the growth of H pylori. METHODS:Standard H pylori strain NCTC 11637 and 4 clinical isolates with different levels of GGT activity as measured by an ...

journal_title：World journal of gastroenterology

authors： Gong M,Ho B

更新日期：2004-10-15 00:00:00

abstract：:Patients with inflammatory bowel disease (IBD) can be affected by other unrelated diseases. These are called comorbid conditions, and can include any secondary health problem that affects a person suffering from a primary or main disease, and which is neither linked physiopathologically to the primary condition, nor i...

journal_title：World journal of gastroenterology

authors： Román AL,Muñoz F

更新日期：2011-06-14 00:00:00

abstract：AIM:To investigate the level of gastric ghrelin in stomach mucosa of dyspeptic patients in relation to Helicobacter pylori (H pylori) infection, bacterial cytotoxicity, topography and gender. METHODS:The study comprised 40 premenopausal women (19 H pylori positive) and 48 men (17 H pylori positive) with functional dys...

journal_title：World journal of gastroenterology

authors： Stec-Michalska K,Malicki S,Michalski B,Peczek L,Wisniewska-Jarosinska M,Nawrot B

更新日期：2009-11-21 00:00:00

abstract：:Helicobacter pylori (H. pylori) is a prevalent, worldwide, chronic infection. Choice of treatment can be modified according to antibiotic-resistance rates of H. pylori. The ideal therapeutic regimen for H. pylori infection should achieve an eradication rate of ≥ 80%. In some countries, triple therapy with a proton-pum...

journal_title：World journal of gastroenterology

authors： Alahdab YO,Kalayci C

更新日期：2014-05-14 00:00:00

abstract：:In colon cancer, classic disease staging remains the key prognosis and treatment determinant. Although adjuvant chemotherapy has an established role in stage III colon cancer patients, in stage II it is still a subject of controversy due to its restriction to a small subgroup of patients with high-risk histopathologic...

journal_title：World journal of gastroenterology

authors： Saridaki Z,Souglakos J,Georgoulias V

更新日期：2014-06-14 00:00:00

abstract：:The importance of the safety of healthy living liver donors is widely recognized during donor hepatectomy which is associated with blood loss, transfusion, and subsequent post-operative morbidity. Although the low central venous pressure (CVP) technique can still be effective, it may not be advantageous concerning the...

journal_title：World journal of gastroenterology

authors： Choi SS,Kim SH,Kim YK

更新日期：2015-12-07 00:00:00

abstract：:Over the past decade, research has shown that aberrant expression of microRNA (miRNA) is involved in colorectal cancer development and progression. MicroRNAs are small sequences of non-coding RNA that regulate expression of genes involved in important cellular functions, such as cell differentiation, multiplication, a...

journal_title：World journal of gastroenterology

authors： Hollis M,Nair K,Vyas A,Chaturvedi LS,Gambhir S,Vyas D

更新日期：2015-07-21 00:00:00

abstract：:A 70-year-old woman was found to have 2 cystic lesions in the head of the pancreas on abdominal ultrasonography during a routine medical examination. Endoscopic ultrasonography (EUS) and magnetic resonance cholangiopancreatography showed multilocular cysts in the head of the pancreas without dilation of the main pancr...

journal_title：World journal of gastroenterology

authors： Urata T,Naito Y,Izumi Y,Takekuma Y,Yokomizo H,Nagamine M,Fukuda S,Notohara K,Hifumi M

更新日期：2013-12-21 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. NAFLD includes a wide spectrum of liver conditions ranging from simple steatosis to nonalcoholic steatohepatitis and advanced hepatic fibrosis. NAFLD has been recognized as a hepatic manifestation of metabolic syndrome linked w...

journal_title：World journal of gastroenterology

authors： Fotbolcu H,Zorlu E

更新日期：2016-04-28 00:00:00

abstract：:Single-port laparoscopic surgery (SPLS) is proposed to be a step towards minimizing the invasiveness of surgery, and has since gained popularity in several surgical sub-specialties including hepatopancreatobiliary surgery. SPLS has since been applied to cholecystectomy, liver resection as well as pancreatectomy for a ...

journal_title：World journal of gastroenterology

authors： Chang SK,Lee KY

更新日期：2014-10-21 00:00:00

abstract：:Hepatitis C virus (HCV) infection disrupts the normal metabolism processes, but is also influenced by several of the host's metabolic factors. An obvious and significantly detrimental pathophysiological feature of HCV infection is insulin resistance in hepatic and peripheral tissues. Substantial research efforts have ...

journal_title：World journal of gastroenterology

authors： Kawaguchi Y,Mizuta T

更新日期：2014-03-21 00:00:00

abstract：AIM:To investigate the individual and combined effects of allopurinol and hyperbaric oxygen (HBO) therapy on biochemical and histopathological changes, oxidative stress, and bacterial translocation (BT) in the experimental rat acute pancreatitis (AP). METHODS:Eighty-five Sprague-Dawley rats were included in the study....

journal_title：World journal of gastroenterology

authors： Comert B,Isik AT,Aydin S,Bozoglu E,Unal B,Deveci S,Mas N,Cinar E,Mas MR

更新日期：2007-12-14 00:00:00